Advances in Hydrogen/Deuterium Exchange Mass Spectrometry and the Pursuit of Challenging Biological Systems
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Title
Advances in Hydrogen/Deuterium Exchange Mass Spectrometry and the Pursuit of Challenging Biological Systems
Authors
Keywords
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Journal
CHEMICAL REVIEWS
Volume -, Issue -, Pages -
Publisher
American Chemical Society (ACS)
Online
2021-09-08
DOI
10.1021/acs.chemrev.1c00279
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- (2021) Haofeng Sun et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Effects of Temperature and Relative Humidity in D2O on Solid-state Hydrogen Deuterium Exchange Mass Spectrometry (ssHDX-MS)
- (2021) Rishabh Tukra et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
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- (2021) Shaunak Raval et al. ANALYTICAL CHEMISTRY
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- (2021) Juan P. Rincon Pabon et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Epitope and Paratope Mapping by HDX-MS Combined with SPR Elucidates the Difference in Bactericidal Activity of Two Anti-NadA Monoclonal Antibodies
- (2021) Laura R. Grauslund et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
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- (2021) Nicole D. Wagner et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
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- (2021) Bradley B. Stocks et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets
- (2021) Palur V Raghuvamsi et al. eLife
- HDXmodeller: an online webserver for high-resolution HDX-MS with auto-validation
- (2021) Ramin Ekhteiari Salmas et al. Communications Biology
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- (2021) Clint Vorauer et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Recommendations for the Propagation of Uncertainty in Hydrogen Exchange-Mass Spectrometric Measurements
- (2021) David D. Weis JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Mapping binding epitopes of monoclonal antibodies targeting major histocompatibility complex class I chain-related A (MICA) with hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry
- (2020) Richard Y.-C. Huang et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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- (2020) Eric Largy et al. ANALYTICAL CHEMISTRY
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- (2020) Richard T. Bradshaw et al. BIOPHYSICAL JOURNAL
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- (2020) Kevin B Dagbay et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2020) Sang-Min Lee et al. JOURNAL OF MOLECULAR BIOLOGY
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- (2020) Amit K. Singh et al. JOURNAL OF MOLECULAR BIOLOGY
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- (2020) Kate Groves et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
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- (2020) Kjetil Hansen et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
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- (2020) James Mullahoo et al. METHODS
- Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS
- (2020) Yangyang Bian et al. Nature Communications
- Bacterial Hsp70 resolves misfolded states and accelerates productive folding of a multi-domain protein
- (2020) Rahmi Imamoglu et al. Nature Communications
- The Order-Disorder Continuum: Linking Predictions of Protein Structure and Disorder through Molecular Simulation
- (2020) Claire C. Hsu et al. Scientific Reports
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- (2020) Moshe Giladi et al. Frontiers in Pharmacology
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- (2020) Zhongqi Zhang ANALYTICAL CHEMISTRY
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- (2020) Chris Barton et al. ANALYTICAL CHEMISTRY
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- (2020) Daniel T. Weltz Wollenberg et al. ANALYTICAL CHEMISTRY
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- (2020) Mengru Mira Zhang et al. ANALYTICAL CHEMISTRY
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- (2020) Laura Corrales-Guerrero et al. NUCLEIC ACIDS RESEARCH
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- (2020) John R. Engen et al. TRENDS IN BIOCHEMICAL SCIENCES
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- (2020) Weronika Puchała et al. BIOINFORMATICS
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- (2020) Anna Skorupska et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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- (2020) Xiaoshan Shi et al. JOURNAL OF CELL BIOLOGY
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- (2020) Zachary J. Hauseman et al. MOLECULAR CELL
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- (2020) Rajashekar Kammari et al. MOLECULAR PHARMACEUTICS
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- (2020) Ryan J. Lumpkin et al. Nature Communications
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- (2020) Huanming Wu et al. REVIEWS IN ANALYTICAL CHEMISTRY
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- (2020) Michael J. Watson et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
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- (2019) Sneha R. Kabaria et al. ANALYTICA CHIMICA ACTA
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- (2019) Samantha D Heitz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2019) Marc B. Taraban et al. MAGNETIC RESONANCE IN CHEMISTRY
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- (2019) Yue Shen et al. ANALYTICAL CHEMISTRY
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- (2019) Darya Urusova et al. Nature Microbiology
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- Reference Parameters for Protein Hydrogen Exchange Rates
- (2018) David Nguyen et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Quantitative analysis of glycation and its impact on antigen binding
- (2018) Jingjie Mo et al. mAbs
- Mass spectrometry-enabled structural biology of membrane proteins
- (2018) Antonio N. Calabrese et al. METHODS
- Hydrogen-deuterium exchange mass spectrometry reveals folding and allostery in protein-protein interactions
- (2018) Cesar A. Ramirez-Sarmiento et al. METHODS
- MS-based conformation analysis of recombinant proteins in design, optimization and development of biopharmaceuticals
- (2018) Devrishi Goswami et al. METHODS
- Contemporary hydrogen deuterium exchange mass spectrometry
- (2018) Irina Oganesyan et al. METHODS
- Probing the Conformation of an IgG1 Monoclonal Antibody in Lyophilized Solids Using Solid-State Hydrogen–Deuterium Exchange with Mass Spectrometric Analysis (ssHDX-MS)
- (2018) Ehab M. Moussa et al. MOLECULAR PHARMACEUTICS
- Effects of Drying Process on an IgG1 Monoclonal Antibody Using Solid-State Hydrogen Deuterium Exchange with Mass Spectrometric Analysis (ssHDX-MS)
- (2018) Ehab M. Moussa et al. PHARMACEUTICAL RESEARCH
- Comparative Analyses of Data Independent Acquisition Mass Spectrometric Approaches: DIA, WiSIM-DIA, and Untargeted DIA
- (2018) Frank Koopmans et al. PROTEOMICS
- Conformational analysis of complex protein states by hydrogen/deuterium exchange mass spectrometry (HDX-MS): Challenges and emerging solutions
- (2018) Esben Trabjerg et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus
- (2018) Estefania Fernandez et al. mBio
- Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
- (2018) Rosi Fassler et al. Jove-Journal of Visualized Experiments
- Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT
- (2018) Patrick S. Merkle et al. Science Advances
- Epitope Mapping by HDX-MS Elucidates the Surface Coverage of Antigens Associated with High Blocking Efficiency of Antibodies to Birch Pollen Allergen
- (2018) Qian Zhang et al. ANALYTICAL CHEMISTRY
- Ordered opening of LDL receptor binding domain of human apolipoprotein E3 revealed by hydrogen/deuterium exchange mass spectrometry and fluorescence spectroscopy
- (2018) Liping Yang et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin
- (2018) Abhishek Bandyopadhyay et al. JOURNAL OF MOLECULAR BIOLOGY
- Interpreting Hydrogen-Deuterium Exchange Events in Proteins Using Atomistic Simulations: Case Studies on Regulators of G-protein Signaling Proteins
- (2018) Hossein Mohammadiarani et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Prediction of the Presence of a Seventh Ankyrin Repeat in IκBε from Homology Modeling Combined with Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)
- (2018) Kristen M. Ramsey et al. PROTEIN SCIENCE
- Light-Driven Domain Mechanics of a Minimal Phytochrome Photosensory Module Studied by EPR
- (2018) Tufa E. Assafa et al. STRUCTURE
- Thiol-ene Microfluidic Chip for Performing Hydrogen/Deuterium Exchange of Proteins at Subsecond Time Scales
- (2018) Rasmus R. Svejdal et al. ANALYTICAL CHEMISTRY
- Hydrogen–Deuterium Exchange Epitope Mapping Reveals Distinct Neutralizing Mechanisms for Two Monoclonal Antibodies against Diphtheria Toxin
- (2018) Shaolong Zhu et al. BIOCHEMISTRY
- Accurate Prediction of Amide Exchange in the Fast Limit Reveals Thrombin Allostery
- (2018) Phineus R.L. Markwick et al. BIOPHYSICAL JOURNAL
- Tri-arginine exosite patch of caspase-6 recruits substrates for hydrolysis
- (2018) Derek J. MacPherson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The ubiquitin ligase SspH1 from Salmonella uses a modular and dynamic E3 domain to catalyze substrate ubiquitylation
- (2018) Matt Cook et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Evidence for a Partially Stalled γ Rotor in F1-ATPase from Hydrogen–Deuterium Exchange Experiments and Molecular Dynamics Simulations
- (2018) Angela Murcia Rios et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Quantitative Evaluation of Native Protein Folds and Assemblies by Hydrogen Deuterium Exchange Mass Spectrometry (HDX-MS)
- (2018) Matthew J. Harris et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- POPPeT: a New Method to Predict the Protection Factor of Backbone Amide Hydrogens
- (2018) Jürgen Claesen et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- High-Resolution HDX-MS of Cytochrome c Using Pepsin/Fungal Protease Type XIII Mixed Bed Column
- (2018) Yoshitomo Hamuro et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Human stress-inducible Hsp70 has a high propensity to form ATP-dependent antiparallel dimers that are differentially regulated by co-chaperone binding
- (2018) Filip Trcka et al. MOLECULAR & CELLULAR PROTEOMICS
- Impact of Tryptophan Oxidation in Complementarity-Determining Regions of Two Monoclonal Antibodies on Structure-Function Characterized by Hydrogen-Deuterium Exchange Mass Spectrometry and Surface Plasmon Resonance
- (2018) Tyler Hageman et al. PHARMACEUTICAL RESEARCH
- Uncovering metastability and disassembly hotspots in whole viral particles
- (2018) Ranita Ramesh et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- HDX-MS reveals orthosteric and allosteric changes in apolipoprotein-D structural dynamics upon binding of progesterone
- (2018) Claudia S. Kielkopf et al. PROTEIN SCIENCE
- Protein Dynamics Revealed by Hydrogen Deuterium Exchange Mass Spectrometry: Correlation between Experiments and Simulation
- (2018) Liwen Huang et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Hydrogen-Deuterium Exchange Coupled to Top- and Middle-Down Mass Spectrometry Reveals Histone Tail Dynamics before and after Nucleosome Assembly
- (2018) Kelly R. Karch et al. STRUCTURE
- Direct protein-lipid interactions shape the conformational landscape of secondary transporters
- (2018) Chloe Martens et al. Nature Communications
- Calcium sensing by the STIM1 ER-luminal domain
- (2018) Aparna Gudlur et al. Nature Communications
- The sweet spot for biologics: recent advances in characterization of biotherapeutic glycoproteins
- (2017) Róisín O’Flaherty et al. Expert Review of Proteomics
- IL-1 Family Cytokines Use Distinct Molecular Mechanisms to Signal through Their Shared Co-receptor
- (2017) Sebastian Günther et al. IMMUNITY
- Co(II) and Ni(II) binding of theEscherichia colitranscriptional repressor RcnR orders its N terminus, alters helix dynamics, and reduces DNA affinity
- (2017) Hsin-Ting Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hydrogen–deuterium exchange reveals long-range dynamical allostery in soybean lipoxygenase
- (2017) Adam R. Offenbacher et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Detection of lipid-induced structural changes of the Marburg virus matrix protein VP40 using hydrogen/deuterium exchange-mass spectrometry
- (2017) Kaveesha J. Wijesinghe et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conformational characterization of nerve growth factor-β reveals that its regulatory pro-part domain stabilizes three loop regions in its mature part
- (2017) Esben Trabjerg et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Subzero Celsius separations in three-zone temperature controlled hydrogen deuterium exchange mass spectrometry
- (2017) Thomas E. Wales et al. JOURNAL OF CHROMATOGRAPHY A
- Structural Implications for the Formation and Function of the Complement Effector Protein iC3b
- (2017) Malvina Papanastasiou et al. JOURNAL OF IMMUNOLOGY
- Engineering Aglycosylated IgG Variants with Wild-Type or Improved Binding Affinity to Human Fc Gamma RIIA and Fc Gamma RIIIAs
- (2017) Tiffany F. Chen et al. JOURNAL OF MOLECULAR BIOLOGY
- Application of Dual Protease Column for HDX-MS Analysis of Monoclonal Antibodies
- (2017) Sasidhar N. Nirudodhi et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Structural Dynamics of the GW182 Silencing Domain Including its RNA Recognition motif (RRM) Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry
- (2017) Maja K. Cieplak-Rotowska et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Determination of Equine Cytochrome c Backbone Amide Hydrogen/Deuterium Exchange Rates by Mass Spectrometry Using a Wider Time Window and Isotope Envelope
- (2017) Yoshitomo Hamuro JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Regio-Selective Intramolecular Hydrogen/Deuterium Exchange in Gas-Phase Electron Transfer Dissociation
- (2017) Yoshitomo Hamuro JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Online Hydrogen-Deuterium Exchange Traveling Wave Ion Mobility Mass Spectrometry (HDX-IM-MS): a Systematic Evaluation
- (2017) Adam Cryar et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Characterization of Pre-F-GCN4t, a Modified Human Respiratory Syncytial Virus Fusion Protein Stabilized in a Noncleaved Prefusion Conformation
- (2017) Normand Blais et al. JOURNAL OF VIROLOGY
- Suppressing allostery in epitope mapping experiments using millisecond hydrogen / deuterium exchange mass spectrometry
- (2017) Bin Deng et al. mAbs
- Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex
- (2017) Ming-Yuan Su et al. MOLECULAR CELL
- Solid-State Hydrogen–Deuterium Exchange Mass Spectrometry: Correlation of Deuterium Uptake and Long-Term Stability of Lyophilized Monoclonal Antibody Formulations
- (2017) Balakrishnan S. Moorthy et al. MOLECULAR PHARMACEUTICS
- Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site
- (2017) Eva-Maria Strauch et al. NATURE BIOTECHNOLOGY
- Folding of apomyoglobin: Analysis of transient intermediate structure during refolding using quick hydrogen deuterium exchange and NMR
- (2017) Chiaki NISHIMURA PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Conformational dynamics of a neurotransmitter:sodium symporter in a lipid bilayer
- (2017) Suraj Adhikary et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ligand-induced conformational dynamics of theEscherichia coliNa+/H+antiporter NhaA revealed by hydrogen/deuterium exchange mass spectrometry
- (2017) Martin Lorenz Eisinger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional importance of stripping in NFκB signaling revealed by a stripping-impaired IκBα mutant
- (2017) Holly E. Dembinski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Helical structure, stability, and dynamics in human apolipoprotein E3 and E4 by hydrogen exchange and mass spectrometry
- (2017) Palaniappan S. Chetty et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ligand-induced allostery in the interaction of thePseudomonas aeruginosaheme binding protein with heme oxygenase
- (2017) Daniel J. Deredge et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Conformational dynamics of 1-deoxy-d-xylulose 5-phosphate synthase on ligand binding revealed by H/D exchange MS
- (2017) Jieyu Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Soft interactions and volume exclusion by polymeric crowders can stabilize or destabilize transient structure in disordered proteins depending on polymer concentration
- (2017) Farai I. Rusinga et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA
- (2017) Ian Mitchelle S. de Vera et al. STRUCTURE
- Epitope and Paratope Mapping Reveals Temperature-Dependent Alterations in the Dengue-Antibody Interface
- (2017) Xin-Xiang Lim et al. STRUCTURE
- Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation
- (2017) Joyce J. W. Wong et al. Nature Communications
- HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions
- (2017) Jie Zheng et al. Nature Communications
- Conformational changes in intact dengue virus reveal serotype-specific expansion
- (2017) Xin-Xiang Lim et al. Nature Communications
- Structural disorder and induced folding within two cereal, ABA stress and ripening (ASR) proteins
- (2017) Karama Hamdi et al. Scientific Reports
- Dynamics and ligand-induced conformational changes in human prolyl oligopeptidase analyzed by hydrogen/deuterium exchange mass spectrometry
- (2017) Alexandra Tsirigotaki et al. Scientific Reports
- Computational method allowing Hydrogen-Deuterium Exchange Mass Spectrometry at single amide Resolution
- (2017) Chris Gessner et al. Scientific Reports
- Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization
- (2017) Alba Torrents de la Peña et al. Cell Reports
- Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6
- (2017) Nina Kerres et al. Cell Reports
- Time-resolved ElectroSpray Ionization Hydrogen-deuterium Exchange Mass Spectrometry for Studying Protein Structure and Dynamics
- (2017) Cristina Lento et al. Jove-Journal of Visualized Experiments
- Exploring the Sequence-based Prediction of Folding Initiation Sites in Proteins
- (2017) Daniele Raimondi et al. Scientific Reports
- Application of amide hydrogen/deuterium exchange mass spectrometry for epitope mapping in human cystatin C
- (2016) Martyna Prądzińska et al. AMINO ACIDS
- Hydrogen deuterium exchange mass spectrometry in biopharmaceutical discovery and development – A review
- (2016) Bin Deng et al. ANALYTICA CHIMICA ACTA
- Two-Site Evaluation of the Repeatability and Precision of an Automated Dual-Column Hydrogen/Deuterium Exchange Mass Spectrometry Platform
- (2016) David J. Cummins et al. ANALYTICAL CHEMISTRY
- Understanding the Impact of Methionine Oxidation on the Biological Functions of IgG1 Antibodies Using Hydrogen/Deuterium Exchange Mass Spectrometry
- (2016) Jingjie Mo et al. ANALYTICAL CHEMISTRY
- An Asymmetric Runaway Domain Swap Antithrombin Dimer as a Key Intermediate for Polymerization Revealed by Hydrogen/Deuterium-Exchange Mass Spectrometry
- (2016) Morten Beck Trelle et al. ANALYTICAL CHEMISTRY
- Automated Strong Cation-Exchange Cleanup To Remove Macromolecular Crowding Agents for Protein Hydrogen Exchange Mass Spectrometry
- (2016) Farai I. Rusinga et al. ANALYTICAL CHEMISTRY
- Removal of N-Linked Glycosylations at Acidic pH by PNGase A Facilitates Hydrogen/Deuterium Exchange Mass Spectrometry Analysis of N-Linked Glycoproteins
- (2016) Pernille Foged Jensen et al. ANALYTICAL CHEMISTRY
- Protein Folding—How and Why: By Hydrogen Exchange, Fragment Separation, and Mass Spectrometry
- (2016) S. Walter Englander et al. Annual Review of Biophysics
- Membrane Interactions, Ligand-Dependent Dynamics, and Stability of Cytochrome P4503A4 in Lipid Nanodiscs
- (2016) Nicholas A. Treuheit et al. BIOCHEMISTRY
- Evidence of Allosteric Enzyme Regulation via Changes in Conformational Dynamics: A Hydrogen/Deuterium Exchange Investigation of Dihydrodipicolinate Synthase
- (2016) Modupeola A. Sowole et al. BIOCHEMISTRY
- Probing the Impact of Local Structural Dynamics of Conformational Epitopes on Antibody Recognition
- (2016) Yu Liang et al. BIOCHEMISTRY
- Effect of Fc-Glycan Structure on the Conformational Stability of IgG Revealed by Hydrogen/Deuterium Exchange and Limited Proteolysis
- (2016) Jing Fang et al. BIOCHEMISTRY
- Comparative higher-order structure analysis of antibody biosimilars using combined bottom-up and top-down hydrogen-deuterium exchange mass spectrometry
- (2016) Jingxi Pan et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- MEMHDX: An interactive tool to expedite the statistical validation and visualization of large HDX-MS datasets
- (2016) Véronique Hourdel et al. BIOINFORMATICS
- Binding of NF κ B Appears to Twist the Ankyrin Repeat Domain of I κ B α
- (2016) Morten Beck Trelle et al. BIOPHYSICAL JOURNAL
- Early Folding Events, Local Interactions, and Conservation of Protein Backbone Rigidity
- (2016) Rita Pancsa et al. BIOPHYSICAL JOURNAL
- Conformational insight into multi-protein signaling assemblies by hydrogen–deuterium exchange mass spectrometry
- (2016) Rane A Harrison et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Mapping of the Allosteric Site in Cholesterol Hydroxylase CYP46A1 for Efavirenz, a Drug That Stimulates Enzyme Activity
- (2016) Kyle W. Anderson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Efficient Qualitative and Quantitative Determination of Antigen-induced Immune Responses
- (2016) Danlin Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biophysical Evidence for Intrinsic Disorder in the C-terminal Tails of the Epidermal Growth Factor Receptor (EGFR) and HER3 Receptor Tyrosine Kinases
- (2016) Theodore R. Keppel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- H7N9 influenza virus neutralizing antibodies that possess few somatic mutations
- (2016) Natalie J. Thornburg et al. JOURNAL OF CLINICAL INVESTIGATION
- Structural Stability and Local Dynamics in Disease-Causing Mutants of Human Apolipoprotein A-I: What Makes the Protein Amyloidogenic?
- (2016) Madhurima Das et al. JOURNAL OF MOLECULAR BIOLOGY
- Structural Dynamics in Ras and Related Proteins upon Nucleotide Switching
- (2016) Rane A. Harrison et al. JOURNAL OF MOLECULAR BIOLOGY
- Pathogenic Mutations within the Disordered Palindromic Region of the Prion Protein Induce Structure Therein and Accelerate the Formation of Misfolded Oligomers
- (2016) A.T. Sabareesan et al. JOURNAL OF MOLECULAR BIOLOGY
- Rapid Conformational Analysis of Protein Drugs in Formulation by Hydrogen/Deuterium Exchange Mass Spectrometry
- (2016) Zeinab E. Nazari et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- A Residue-Resolved Bayesian Approach to Quantitative Interpretation of Hydrogen–Deuterium Exchange from Mass Spectrometry: Application to Characterizing Protein–Ligand Interactions
- (2016) Daniel J. Saltzberg et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Protein species-specific characterization of conformational change induced by multisite phosphorylation
- (2016) Jingxi Pan et al. Journal of Proteomics
- Real-time HD Exchange Kinetics of Proteins from Buffered Aqueous Solution with Electrothermal Supercharging and Top-Down Tandem Mass Spectrometry
- (2016) Catherine C. Going et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Tuning a High Transmission Ion Guide to Prevent Gas-Phase Proton Exchange During H/D Exchange MS Analysis
- (2016) Miklos Guttman et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Characterization of Aggregation Propensity of a Human Fc-Fusion Protein Therapeutic by Hydrogen/Deuterium Exchange Mass Spectrometry
- (2016) Richard Y.-C. Huang et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Conformational Analysis of Proteins in Highly Concentrated Solutions by Dialysis-Coupled Hydrogen/Deuterium Exchange Mass Spectrometry
- (2016) Damian Houde et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Epitope-Independent Purification of Native-Like Envelope Trimers from Diverse HIV-1 Isolates
- (2016) Hans P. Verkerke et al. JOURNAL OF VIROLOGY
- Changes in Structure and Antigenicity of HIV-1 Env Trimers Resulting from Removal of a Conserved CD4 Binding Site-Proximal Glycan
- (2016) Yu Liang et al. JOURNAL OF VIROLOGY
- Computational methods and challenges in hydrogen/deuterium exchange mass spectrometry
- (2016) Jürgen Claesen et al. MASS SPECTROMETRY REVIEWS
- On-tissue Direct Monitoring of Global Hydrogen/Deuterium Exchange by MALDI Mass Spectrometry: Tissue Deuterium Exchange Mass Spectrometry (TDXMS)
- (2016) Jusal Quanico et al. MOLECULAR & CELLULAR PROTEOMICS
- Six alternative proteases for mass spectrometry–based proteomics beyond trypsin
- (2016) Piero Giansanti et al. Nature Protocols
- Heavy lessons in protein allostery
- (2016) Lars Konermann NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV
- (2016) M Gordon Joyce et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Investigating the Role of Artemin Glycosylation
- (2016) Qiu Danwen et al. PHARMACEUTICAL RESEARCH
- Epitope Mapping of a Monoclonal Antibody Directed against Neisserial Heparin Binding Antigen Using Next Generation Sequencing of Antigen-Specific Libraries
- (2016) Maria Domina et al. PLoS One
- Cytochromecfolds through foldon-dependent native-like intermediates in an ordered pathway
- (2016) Wenbing Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Load-dependent destabilization of the γ-rotor shaft in FOF1ATP synthase revealed by hydrogen/deuterium-exchange mass spectrometry
- (2016) Siavash Vahidi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Broadly neutralizing epitopes in thePlasmodium vivaxvaccine candidate Duffy Binding Protein
- (2016) Edwin Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanism of Lipid Binding of Human Apolipoprotein E3 by Hydrogen/Deuterium Exchange/Mass Spectrometry and Fluorescence Polarization
- (2016) Charina S. Fabilane et al. PROTEIN AND PEPTIDE LETTERS
- Conformational characterization of the intrinsically disordered protein Chibby: Interplay between structural elements in target recognition
- (2016) Ryan C. Killoran et al. PROTEIN SCIENCE
- Using hydrogen deuterium exchange mass spectrometry to engineer optimized constructs for crystallization of protein complexes: Case study of PI4KIIIβ with Rab11
- (2016) Melissa L. Fowler et al. PROTEIN SCIENCE
- Higher-order structural interrogation of antibodies using middle-down hydrogen/deuterium exchange mass spectrometry
- (2016) Jingxi Pan et al. Chemical Science
- Heavy lessons in protein allostery
- (2016) Lars Konermann NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV
- (2016) M Gordon Joyce et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mapping light-driven conformational changes within the photosensory module of plant phytochrome B
- (2016) Silke von Horsten et al. Scientific Reports
- Predicting Allosteric Effects from Orthosteric Binding in Hsp90-Ligand Interactions: Implications for Fragment-Based Drug Design
- (2016) Arun Chandramohan et al. PLoS Computational Biology
- High Resolution Mapping of Bactericidal Monoclonal Antibody Binding Epitopes on Staphylococcus aureus Antigen MntC
- (2016) Alexey V. Gribenko et al. PLoS Pathogens
- The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain
- (2016) Simon Mysling et al. eLife
- Blue light-induced LOV domain dimerization enhances the affinity of Aureochrome 1a for its target DNA sequence
- (2016) Udo Heintz et al. eLife
- The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding
- (2016) Simon Mysling et al. eLife
- Membrane-Associated Conformation of HIV-1 Nef Investigated with Hydrogen Exchange Mass Spectrometry at a Langmuir Monolayer
- (2015) Gregory F. Pirrone et al. ANALYTICAL CHEMISTRY
- Recombinant Nepenthesin II for Hydrogen/Deuterium Exchange Mass Spectrometry
- (2015) Menglin Yang et al. ANALYTICAL CHEMISTRY
- Probing the Conformational and Functional Consequences of Disulfide Bond Engineering in Growth Hormone by Hydrogen–Deuterium Exchange Mass Spectrometry Coupled to Electron Transfer Dissociation
- (2015) Signe T. Seger et al. ANALYTICAL CHEMISTRY
- Determination of Histidine pKa Values in the Propeptides of Furin and Proprotein Convertase 1/3 Using Histidine Hydrogen–Deuterium Exchange Mass Spectrometry
- (2015) Johannes Elferich et al. ANALYTICAL CHEMISTRY
- Antibody Structural Integrity of Site-Specific Antibody-Drug Conjugates Investigated by Hydrogen/Deuterium Exchange Mass Spectrometry
- (2015) Lucy Yan Pan et al. ANALYTICAL CHEMISTRY
- Kinetics of Protein Complex Dissociation Studied by Hydrogen/Deuterium Exchange and Mass Spectrometry
- (2015) Zhe Zhang et al. ANALYTICAL CHEMISTRY
- Advances in Ultrahigh-Pressure Liquid Chromatography Technology and System Design
- (2015) Jelle De Vos et al. ANALYTICAL CHEMISTRY
- Mass Spectrometric Approach for Characterizing the Disordered Tail Regions of the Histone H2A/H2B Dimer
- (2015) Kazumi Saikusa et al. ANALYTICAL CHEMISTRY
- Utilizing Microchip Capillary Electrophoresis Electrospray Ionization for Hydrogen Exchange Mass Spectrometry
- (2015) William A. Black et al. ANALYTICAL CHEMISTRY
- Fast Comparative Structural Characterization of Intact Therapeutic Antibodies Using Hydrogen–Deuterium Exchange and Electron Transfer Dissociation
- (2015) Jingxi Pan et al. ANALYTICAL CHEMISTRY
- Conformational Analysis of Large and Highly Disulfide-Stabilized Proteins by Integrating Online Electrochemical Reduction into an Optimized H/D Exchange Mass Spectrometry Workflow
- (2015) Esben Trabjerg et al. ANALYTICAL CHEMISTRY
- Hydrogen Exchange Mass Spectrometry of Proteins at Langmuir Monolayers
- (2015) Gregory F. Pirrone et al. ANALYTICAL CHEMISTRY
- Analytical Aspects of Hydrogen Exchange Mass Spectrometry
- (2015) John R. Engen et al. Annual Review of Analytical Chemistry
- The intrinsically disordered tails of PTEN and PTEN-L have distinct roles in regulating substrate specificity and membrane activity
- (2015) G. R. Masson et al. BIOCHEMICAL JOURNAL
- Thrombomodulin Binding Selects the Catalytically Active Form of Thrombin
- (2015) Lindsey D. Handley et al. BIOCHEMISTRY
- Challenges in the Interpretation of Protein H/D Exchange Data: A Molecular Dynamics Simulation Perspective
- (2015) Robert G. McAllister et al. BIOCHEMISTRY
- Continuous and Pulsed Hydrogen–Deuterium Exchange and Mass Spectrometry Characterize CsgE Oligomerization
- (2015) Hanliu Wang et al. BIOCHEMISTRY
- Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes
- (2015) Steven W. de Taeye et al. CELL
- Steric gate residues of Y-family DNA polymerases DinB and pol kappa are crucial for dNTP-induced conformational change
- (2015) Philip Nevin et al. DNA REPAIR
- Getting to the core of protein pharmaceuticals – Comprehensive structure analysis by mass spectrometry
- (2015) Ulrike Leurs et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- The role of structural proteomics in vaccine development: recent advances and future prospects
- (2015) Danilo Donnarumma et al. Expert Review of Proteomics
- Noncognate DNA damage prevents the formation of the active conformation of the Y-family DNA polymerases DinB and DNA polymerase κ
- (2015) Philip Nevin et al. FEBS Journal
- Fc glycans of therapeutic antibodies as critical quality attributes
- (2015) Dietmar Reusch et al. GLYCOBIOLOGY
- Structural Characterization of Phosducin and Its Complex with the 14-3-3 Protein
- (2015) Miroslava Kacirova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Recognition ofN-Glycoforms in Human Chorionic Gonadotropin by Monoclonal Antibodies and Their Interaction Motifs
- (2015) Daoyuan Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conformational Destabilization of Immunoglobulin G Increases the Low pH Binding Affinity with the Neonatal Fc Receptor
- (2015) Benjamin T. Walters et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lysine residues in the N-terminal huntingtin amphipathicα-helix play a key role in peptide aggregation
- (2015) James R. Arndt et al. JOURNAL OF MASS SPECTROMETRY
- Hydrogen-Deuterium Exchange Mass Spectrometry as an Emerging Analytical Tool for Stabilization and Formulation Development of Therapeutic Monoclonal Antibodies
- (2015) Ranajoy Majumdar et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Localizing Carbohydrate Binding Sites in Proteins Using Hydrogen/Deuterium Exchange Mass Spectrometry
- (2015) Jingjing Zhang et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- HDX Match Software for the Data Analysis of Top-Down ECD-FTMS Hydrogen/Deuterium Exchange Experiments
- (2015) Evgeniy V. Petrotchenko et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- A Comparison of Energy-Resolved Vibrational Activation/Dissociation Characteristics of Protonated and Sodiated High Mannose N-Glycopeptides
- (2015) Forouzan Aboufazeli et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Effective Application of Bicelles for Conformational Analysis of G Protein-Coupled Receptors by Hydrogen/Deuterium Exchange Mass Spectrometry
- (2015) Nguyen Minh Duc et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers
- (2015) Rajesh P. Ringe et al. JOURNAL OF VIROLOGY
- Hydrogen exchange mass spectrometry reveals protein interfaces and distant dynamic coupling effects during the reversible self-association of an IgG1 monoclonal antibody
- (2015) Jayant Arora et al. mAbs
- Inhibition of Pro-Apoptotic BAX by a Noncanonical Interaction Mechanism
- (2015) Lauren A. Barclay et al. MOLECULAR CELL
- Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
- (2015) Young Do Kwon et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Insight into the Unfolding Properties of Chd64, a Small, Single Domain Protein with a Globular Core and Disordered Tails
- (2015) Aneta Tarczewska et al. PLoS One
- Local and global structural drivers for the photoactivation of the orange carotenoid protein
- (2015) Sayan Gupta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Relating gas phase to solution conformations: Lessons from disordered proteins
- (2015) Rebecca Beveridge et al. PROTEOMICS
- A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen
- (2015) A. Impagliazzo et al. SCIENCE
- HIV-1 neutralizing antibodies induced by native-like envelope trimers
- (2015) R. W. Sanders et al. SCIENCE
- Dynamic Changes during Acid-Induced Activation of Influenza Hemagglutinin
- (2015) Natalie K. Garcia et al. STRUCTURE
- Replication in bioanalytical studies with HDX MS: aim as high as possible
- (2015) Jamie A Moroco et al. Bioanalysis
- Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env
- (2015) Miklos Guttman et al. Nature Communications
- Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
- (2015) Young Do Kwon et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mass Spectrometric Approaches to Study Protein Structure and Interactions in Lyophilized Powders
- (2015) Balakrishnan S. Moorthy et al. Jove-Journal of Visualized Experiments
- Hyperphosphorylation of Intrinsically Disordered Tau Protein Induces an Amyloidogenic Shift in Its Conformational Ensemble
- (2015) Shaolong Zhu et al. PLoS One
- Characterization of the Human Folate Receptor Alpha Via Novel Antibody-Based Probes
- (2015) Daniel J. O’Shannessy et al. Oncotarget
- Hydrogen–deuterium exchange in imidazole as a tool for studying histidine phosphorylation
- (2014) Małgorzata Cebo et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Higher order structure characterization of protein therapeutics by hydrogen/deuterium exchange mass spectrometry
- (2014) Richard Y.-C. Huang et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Effects of Protein–Ligand Interactions on Hydrogen/Deuterium Exchange Kinetics: Canonical and Noncanonical Scenarios
- (2014) Modupeola A. Sowole et al. ANALYTICAL CHEMISTRY
- Toward Standardizing Deuterium Content Reporting in Hydrogen Exchange-MS
- (2014) Joey G. Sheff et al. ANALYTICAL CHEMISTRY
- Understanding the Conformational Impact of Chemical Modifications on Monoclonal Antibodies with Diverse Sequence Variation Using Hydrogen/Deuterium Exchange Mass Spectrometry and Structural Modeling
- (2014) Aming Zhang et al. ANALYTICAL CHEMISTRY
- Aspartic Protease Nepenthesin-1 as a Tool for Digestion in Hydrogen/Deuterium Exchange Mass Spectrometry
- (2014) Alan Kadek et al. ANALYTICAL CHEMISTRY
- Dissecting the Binding Mode of Low Affinity Phage Display Peptide Ligands to Protein Targets by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry
- (2014) Ulrike Leurs et al. ANALYTICAL CHEMISTRY
- Approach to Characterization of the Higher Order Structure of Disulfide-Containing Proteins Using Hydrogen/Deuterium Exchange and Top-Down Mass Spectrometry
- (2014) Guanbo Wang et al. ANALYTICAL CHEMISTRY
- A Conformational Investigation of Propeptide Binding to the Integral Membrane Protein γ-Glutamyl Carboxylase Using Nanodisc Hydrogen Exchange Mass Spectrometry
- (2014) Christine H. Parker et al. BIOCHEMISTRY
- Discovery and characterization of a novel extremely acidic bacterialN-glycanase with combined advantages of PNGase F and A
- (2014) Ting Wang et al. BIOSCIENCE REPORTS
- QUDeX-MS: hydrogen/deuterium exchange calculation for mass spectra with resolved isotopic fine structure
- (2014) Joseph P Salisbury et al. BMC BIOINFORMATICS
- Classification of Intrinsically Disordered Regions and Proteins
- (2014) Robin van der Lee et al. CHEMICAL REVIEWS
- Sites Involved in Intra- and Interdomain Allostery Associated with the Activation of Factor VIIa Pinpointed by Hydrogen-Deuterium Exchange and Electron Transfer Dissociation Mass Spectrometry
- (2014) Hongjian Song et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hydrogen-deuterium exchange of α-carbon protons and fragmentation pathways in N-methylated glycine and alanine-containing peptides derivatized by quaternary ammonium salts
- (2014) Remigiusz Bąchor et al. JOURNAL OF MASS SPECTROMETRY
- Extended String Binding Mode of the Phosphorylated Transactivation Domain of Tumor Suppressor p53
- (2014) Masahiko Okuda et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Subzero Temperature Chromatography and Top-Down Mass Spectrometry for Protein Higher-Order Structure Characterization: Method Validation and Application to Therapeutic Antibodies
- (2014) Jingxi Pan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Hexicon 2: Automated Processing of Hydrogen-Deuterium Exchange Mass Spectrometry Data with Improved Deuteration Distribution Estimation
- (2014) Robert Lindner et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life
- (2014) Ranajoy Majumdar et al. mAbs
- Investigating the Interaction between the Neonatal Fc Receptor and Monoclonal Antibody Variants by Hydrogen/Deuterium Exchange Mass Spectrometry
- (2014) Pernille Foged Jensen et al. MOLECULAR & CELLULAR PROTEOMICS
- Predicting Protein Aggregation during Storage in Lyophilized Solids Using Solid State Amide Hydrogen/Deuterium Exchange with Mass Spectrometric Analysis (ssHDX-MS)
- (2014) Balakrishnan S. Moorthy et al. MOLECULAR PHARMACEUTICS
- Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody
- (2014) Enrico Malito et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD4-Induced Activation in a Soluble HIV-1 Env Trimer
- (2014) Miklos Guttman et al. STRUCTURE
- Molecular interaction between natural IgG and ficolin – mechanistic insights on adaptive-innate immune crosstalk
- (2014) Saswati Panda et al. Scientific Reports
- A novel electrochemical method for efficient reduction of disulfide bonds in peptides and proteins prior to MS detection
- (2013) Agnieszka Kraj et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Inhibition of protein carbamylation in urea solution using ammonium-containing buffers
- (2013) Shisheng Sun et al. ANALYTICAL BIOCHEMISTRY
- Identifying Zn-Bound Histidine Residues in Metalloproteins Using Hydrogen–Deuterium Exchange Mass Spectrometry
- (2013) Jia Dong et al. ANALYTICAL CHEMISTRY
- Hydrogen Exchange-Mass Spectrometry Measures Stapled Peptide Conformational Dynamics and Predicts Pharmacokinetic Properties
- (2013) Xiangguo (Eric) Shi et al. ANALYTICAL CHEMISTRY
- Resolving Isotopic Fine Structure to Detect and Quantify Natural Abundance- and Hydrogen/Deuterium Exchange-Derived Isotopomers
- (2013) Qian Liu et al. ANALYTICAL CHEMISTRY
- Analysis of Disordered Proteins Using a Simple Apparatus for Millisecond Quench-Flow H/D Exchange
- (2013) Theodore R. Keppel et al. ANALYTICAL CHEMISTRY
- Electrochemical Reduction of Disulfide-Containing Proteins for Hydrogen/Deuterium Exchange Monitored by Mass Spectrometry
- (2013) Simon Mysling et al. ANALYTICAL CHEMISTRY
- Effect of Pressure-Induced Changes in the Ionization Equilibria of Buffers on Inactivation of Escherichia coli and Staphylococcus aureus by High Hydrostatic Pressure
- (2013) Elisa Gayán et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Effects of Desialylation on Human α1-Acid Glycoprotein–Ligand Interactions
- (2013) Richard Y.-C. Huang et al. BIOCHEMISTRY
- Effects of Salts from the Hofmeister Series on the Conformational Stability, Aggregation Propensity, and Local Flexibility of an IgG1 Monoclonal Antibody
- (2013) Ranajoy Majumdar et al. BIOCHEMISTRY
- Principles of electron capture and transfer dissociation mass spectrometry applied to peptide and protein structure analysis
- (2013) Konstantin O. Zhurov et al. CHEMICAL SOCIETY REVIEWS
- Characterizing rapid, activity-linked conformational transitions in proteins via sub-second hydrogen deuterium exchange mass spectrometry
- (2013) Diana Resetca et al. FEBS Journal
- Mass spectrometry for the biophysical characterization of therapeutic monoclonal antibodies
- (2013) Hao Zhang et al. FEBS LETTERS
- Factor VIII C1 Domain Spikes 2092–2093 and 2158–2159 Comprise Regions That Modulate Cofactor Function and Cellular Uptake
- (2013) Esther Bloem et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of ClpP Protease by ADEP Antibiotics: Insights from Hydrogen Exchange Mass Spectrometry
- (2013) Modupeola A. Sowole et al. JOURNAL OF MOLECULAR BIOLOGY
- Investigating Monoclonal Antibody Aggregation Using a Combination of H/DX-MS and Other Biophysical Measurements
- (2013) Roxana E. Iacob et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Improving Qualitative and Quantitative Performance for MSE-based Label-free Proteomics
- (2013) Nicholas J. Bond et al. JOURNAL OF PROTEOME RESEARCH
- Effects of Traveling Wave Ion Mobility Separation on Data Independent Acquisition in Proteomics Studies
- (2013) Pavel V. Shliaha et al. JOURNAL OF PROTEOME RESEARCH
- H/D Exchange Centroid Monitoring is Insufficient to Show Differences in the Behavior of Protein States
- (2013) Jun Zhang et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Feature Based Retention Time Alignment for Improved HDX MS Analysis
- (2013) John D. Venable et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Rapid Screening for Potential Epitopes Reactive with a Polycolonal Antibody by Solution-Phase H/D Exchange Monitored by FT-ICR Mass Spectrometry
- (2013) Qian Zhang et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Peptide–Column Interactions and Their Influence on Back Exchange Rates in Hydrogen/Deuterium Exchange-MS
- (2013) Joey G. Sheff et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Time Window Expansion for HDX Analysis of an Intrinsically Disordered Protein
- (2013) Devrishi Goswami et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Analysis of Overlapped and Noisy Hydrogen/Deuterium Exchange Mass Spectra
- (2013) Miklos Guttman et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- A Functional Interaction between gp41 and gp120 Is Observed for Monomeric but Not Oligomeric, Uncleaved HIV-1 Env gp140
- (2013) M. Guttman et al. JOURNAL OF VIROLOGY
- Isolate-Specific Differences in the Conformational Dynamics and Antigenicity of HIV-1 gp120
- (2013) T. M. Davenport et al. JOURNAL OF VIROLOGY
- Mutation of Y407 in the CH3 domain dramatically alters glycosylation and structure of human IgG
- (2013) Rebecca J. Rose et al. mAbs
- Conformer-specific characterization of nonnative protein states using hydrogen exchange and top-down mass spectrometry
- (2013) G. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protein hydrogen exchange at residue resolution by proteolytic fragmentation mass spectrometry analysis
- (2013) Z.-Y. Kan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Folding of a large protein at high structural resolution
- (2013) B. T. Walters et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen
- (2013) Enrico Malito et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A decade and a half of protein intrinsic disorder: Biology still waits for physics
- (2013) Vladimir N. Uversky PROTEIN SCIENCE
- Deglycosylation induces extensive dynamics changes in α-amylase revealed by hydrogen/deuterium exchange mass spectrometry
- (2013) Chengjie Ji et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Protein Conformation Ensembles Monitored by HDX Reveal a Structural Rationale for Abscisic Acid Signaling Protein Affinities and Activities
- (2013) Graham M. West et al. STRUCTURE
- Effect of temperature and solvent composition on acid dissociation equilibria, I: Sequenced pssKa determination of compounds commonly used as buffers in high performance liquid chromatography coupled to mass spectroscopy detection
- (2012) Juan M. Padró et al. ANALYTICA CHIMICA ACTA
- Probing protein interactions with hydrogen/deuterium exchange and mass spectrometry—A review
- (2012) Andrew J. Percy et al. ANALYTICA CHIMICA ACTA
- Pepsin Immobilized on High-Strength Hybrid Particles for Continuous Flow Online Digestion at 10 000 psi
- (2012) Joomi Ahn et al. ANALYTICAL CHEMISTRY
- Effective Use of Mass Spectrometry for Glycan and Glycopeptide Structural Analysis
- (2012) Nancy Leymarie et al. ANALYTICAL CHEMISTRY
- Subzero Temperature Chromatography for Reduced Back-Exchange and Improved Dynamic Range in Amide Hydrogen/Deuterium Exchange Mass Spectrometry
- (2012) John D. Venable et al. ANALYTICAL CHEMISTRY
- Measuring Dynamics in Weakly Structured Regions of Proteins Using Microfluidics-Enabled Subsecond H/D Exchange Mass Spectrometry
- (2012) Tamanna Rob et al. ANALYTICAL CHEMISTRY
- Spatially Resolved Protein Hydrogen Exchange Measured by Subzero-Cooled Chip-Based Nanoelectrospray Ionization Tandem Mass Spectrometry
- (2012) Sabine Amon et al. ANALYTICAL CHEMISTRY
- Improved Protein Hydrogen/Deuterium Exchange Mass Spectrometry Platform with Fully Automated Data Processing
- (2012) Zhongqi Zhang et al. ANALYTICAL CHEMISTRY
- Exploring the Conformational Dynamics of the Bovine ADP/ATP Carrier in Mitochondria
- (2012) Martial Rey et al. BIOCHEMISTRY
- Structure and Dynamics of Small Soluble Aβ(1–40) Oligomers Studied by Top-Down Hydrogen Exchange Mass Spectrometry
- (2012) Jingxi Pan et al. BIOCHEMISTRY
- Accessing the reproducibility and specificity of pepsin and other aspartic proteases
- (2012) Joomi Ahn et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Mapping of discontinuous conformational epitopes by amide hydrogen/deuterium exchange mass spectrometry and computational docking
- (2012) Deepangi Pandit et al. JOURNAL OF MOLECULAR RECOGNITION
- Conformational Comparability of Factor IX–Fc Fusion Protein, Factor IX, and Purified Fc Fragment in the Absence and Presence of Calcium
- (2012) Damian Houde et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- In-Source Fragmentation and the Sources of Partially Tryptic Peptides in Shotgun Proteomics
- (2012) Jong-Seo Kim et al. JOURNAL OF PROTEOME RESEARCH
- Hydrogen Exchange Mass Spectrometry: Are We Out of the Quicksand?
- (2012) Roxana E. Iacob et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Improved Sequence Resolution by Global Analysis of Overlapped Peptides in Hydrogen/Deuterium Exchange Mass Spectrometry
- (2012) Piotr G. Fajer et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Polar Aprotic Modifiers for Chromatographic Separation and Back-Exchange Reduction for Protein Hydrogen/Deuterium Exchange Monitored by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
- (2012) Santosh G. Valeja et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Using Hydrogen/Deuterium Exchange Mass Spectrometry to Study Conformational Changes in Granulocyte Colony Stimulating Factor upon PEGylation
- (2012) Hui Wei et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- HDX Workbench: Software for the Analysis of H/D Exchange MS Data
- (2012) Bruce D. Pascal et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Minimizing Carry-Over in an Online Pepsin Digestion System used for the H/D Exchange Mass Spectrometric Analysis of an IgG1 Monoclonal Antibody
- (2012) Ranajoy Majumdar et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Minimizing Back Exchange in the Hydrogen Exchange-Mass Spectrometry Experiment
- (2012) Benjamin T. Walters et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Solution Structure, Conformational Dynamics, and CD4-Induced Activation in Full-Length, Glycosylated, Monomeric HIV gp120
- (2012) Miklos Guttman et al. JOURNAL OF VIROLOGY
- Platform Dependencies in Bottom-up Hydrogen/Deuterium Exchange Mass Spectrometry
- (2012) Kyle M. Burns et al. MOLECULAR & CELLULAR PROTEOMICS
- Nepenthesin from Monkey Cups for Hydrogen/Deuterium Exchange Mass Spectrometry
- (2012) Martial Rey et al. MOLECULAR & CELLULAR PROTEOMICS
- Localized Hydration in Lyophilized Myoglobin by Hydrogen–Deuterium Exchange Mass Spectrometry. 2. Exchange Kinetics
- (2012) Andreas M. Sophocleous et al. MOLECULAR PHARMACEUTICS
- Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars
- (2012) Steven A. Berkowitz et al. NATURE REVIEWS DRUG DISCOVERY
- Dynamics of a bacterial multidrug ABC transporter in the inward- and outward-facing conformations
- (2012) S. Mehmood et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protein hydrogen exchange: Testing current models
- (2012) John J. Skinner et al. PROTEIN SCIENCE
- Monitoring allostery in D2O: a necessary control in studies using hydrogen/deuterium exchange to characterize allosteric regulation
- (2011) Charulata B. Prasannan et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Tracking Hydrogen/Deuterium Exchange at Glycan Sites in Glycoproteins by Mass Spectrometry
- (2011) M. Guttman et al. ANALYTICAL CHEMISTRY
- Slow Histidine H/D Exchange Protocol for Thermodynamic Analysis of Protein Folding and Stability Using Mass Spectrometry
- (2011) Duc T. Tran et al. ANALYTICAL CHEMISTRY
- Mapping Unstructured Regions and Synergistic Folding in Intrinsically Disordered Proteins with Amide H/D Exchange Mass Spectrometry
- (2011) Theodore R. Keppel et al. BIOCHEMISTRY
- Differential hydrogen/deuterium exchange mass spectrometry analysis of protein–ligand interactions
- (2011) Michael J Chalmers et al. Expert Review of Proteomics
- Structural Variations within the Transferrin Binding Site on Transferrin-binding Protein B, TbpB
- (2011) Charles Calmettes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- On the Solution Conformation and Dynamics of the HIV-1 Viral Infectivity Factor
- (2011) Sean R. Marcsisin et al. JOURNAL OF MOLECULAR BIOLOGY
- Prediction of Native-State Hydrogen Exchange from Perfectly Funneled Energy Landscapes
- (2011) Patricio O. Craig et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- HDXFinder: Automated Analysis and Data Reporting of Deuterium/Hydrogen Exchange Mass Spectrometry
- (2011) Danny E. Miller et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- An Efficient and Inexpensive Refrigerated LC System for H/D Exchange Mass Spectrometry
- (2011) Theodore R. Keppel et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- ETD in a Traveling Wave Ion Guide at Tuned Z-Spray Ion Source Conditions Allows for Site-Specific Hydrogen/Deuterium Exchange Measurements
- (2011) Kasper D. Rand et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Automated Hydrogen/Deuterium Exchange Electron Transfer Dissociation High Resolution Mass Spectrometry Measured at Single-Amide Resolution
- (2011) Rachelle R. Landgraf et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- ExMS: Data Analysis for HX-MS Experiments
- (2011) Zhong-Yuan Kan et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Many Overlapping Peptides for Protein Hydrogen Exchange Experiments by the Fragment Separation-Mass Spectrometry Method
- (2011) Leland Mayne et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Quantitative Assessment of Protein Structural Models by Comparison of H/D Exchange MS Data with Exchange Behavior Accurately Predicted by DXCOREX
- (2011) Tong Liu et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Conformational Transitions in the Membrane Scaffold Protein of Phospholipid Bilayer Nanodiscs
- (2011) Christopher R. Morgan et al. MOLECULAR & CELLULAR PROTEOMICS
- Targeted Mass Spectrometric Approach for Biomarker Discovery and Validation with Nonglycosylated Tryptic Peptides from N-linked Glycoproteins in Human Plasma
- (2011) Ju Yeon Lee et al. MOLECULAR & CELLULAR PROTEOMICS
- Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization
- (2011) Mikyung Kim et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Histidine Hydrogen-Deuterium Exchange Mass Spectrometry for Probing the Microenvironment of Histidine Residues in Dihydrofolate Reductase
- (2011) Masaru Miyagi et al. PLoS One
- Crystal structure of the Lassa virus nucleoprotein-RNA complex reveals a gating mechanism for RNA binding
- (2011) K. M. Hastie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fine Details of IGF-1R Activation, Inhibition, and Asymmetry Determined by Associated Hydrogen /Deuterium-Exchange and Peptide Mass Mapping
- (2011) Damian Houde et al. STRUCTURE
- Ebola Virus Glycoprotein Needs an Additional Trigger, beyond Proteolytic Priming for Membrane Fusion
- (2011) Shridhar Bale et al. PLoS Neglected Tropical Diseases
- Effective Removal of Nonionic Detergents in Protein Mass Spectrometry, Hydrogen/Deuterium Exchange, and Proteomics
- (2010) Martial Rey et al. ANALYTICAL CHEMISTRY
- Dynamics of the β2-Adrenergic G-Protein Coupled Receptor Revealed by Hydrogen−Deuterium Exchange
- (2010) Xi Zhang et al. ANALYTICAL CHEMISTRY
- Simultaneous Reduction and Digestion of Proteins with Disulfide Bonds for Hydrogen/Deuterium Exchange Monitored by Mass Spectrometry
- (2010) Hui-Min Zhang et al. ANALYTICAL CHEMISTRY
- Online, High-Pressure Digestion System for Protein Characterization by Hydrogen/Deuterium Exchange and Mass Spectrometry
- (2010) Lisa M. Jones et al. ANALYTICAL CHEMISTRY
- Real-Time Hydrogen/Deuterium Exchange Kinetics via Supercharged Electrospray Ionization Tandem Mass Spectrometry
- (2010) Harry J. Sterling et al. ANALYTICAL CHEMISTRY
- Conformational Analysis of Membrane Proteins in Phospholipid Bilayer Nanodiscs by Hydrogen Exchange Mass Spectrometry
- (2010) Christine M. Hebling et al. ANALYTICAL CHEMISTRY
- Loss of Ammonia during Electron-Transfer Dissociation of Deuterated Peptides as an Inherent Gauge of Gas-Phase Hydrogen Scrambling
- (2010) Kasper D. Rand et al. ANALYTICAL CHEMISTRY
- Deuteration distribution estimation with improved sequence coverage for HX/MS experiments
- (2010) Xinghua Lou et al. BIOINFORMATICS
- Computing H/D-Exchange rates of single residues from data of proteolytic fragments
- (2010) Ernst Althaus et al. BMC BIOINFORMATICS
- Shift of pH-Value During Thermal Treatments in Buffer Solutions and Selected Foods
- (2010) Kai Reineke et al. INTERNATIONAL JOURNAL OF FOOD PROPERTIES
- Methods for the analysis of high precision differential hydrogen–deuterium exchange data
- (2010) Michael J. Chalmers et al. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
- Investigation of amide hydrogen back-exchange in Asp and His repeats measured by hydrogen (1H/2H) exchange mass spectrometry
- (2010) Kasper D. Rand et al. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
- Effects of glycosylation on the stability and flexibility of a metastable protein: The human serpin α1-antitrypsin
- (2010) Anindya Sarkar et al. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
- False EX1 signatures caused by sample carryover during HX MS analyses
- (2010) Jing Fang et al. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
- Hydrophobic peptides affect binding of calmodulin and Ca2+ as explored by H/D amide exchange and mass spectrometry
- (2010) Justin B. Sperry et al. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
- MSTools—Web based application for visualization and presentation of HXMS data
- (2010) Daniel Kavan et al. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
- HK97 Maturation Studied by Crystallography and H/2H Exchange Reveals the Structural Basis for Exothermic Particle Transitions
- (2010) Ilya Gertsman et al. JOURNAL OF MOLECULAR BIOLOGY
- The Utility of Hydrogen/Deuterium Exchange Mass Spectrometry in Biopharmaceutical Comparability Studies
- (2010) Damian Houde et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Protein-peptide affinity determination using an H/D exchange dilution strategy: Application to antigen-antibody interactions
- (2010) Tingting Tu et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Automated data reduction for hydrogen/deuterium exchange experiments, enabled by high-resolution fourier transform ion cyclotron resonance mass spectrometry
- (2010) Sasa Kazazic et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Local Conformational Stability of HIV-1 gp120 in Unliganded and CD4-Bound States as Defined by Amide Hydrogen/Deuterium Exchange
- (2010) L. Kong et al. JOURNAL OF VIROLOGY
- Cleavage of IgGs by proteases associated with invasive diseases
- (2010) Randall J. Brezski et al. mAbs
- Post-translational Modifications Differentially Affect IgG1 Conformation and Receptor Binding
- (2010) Damian Houde et al. MOLECULAR & CELLULAR PROTEOMICS
- Pressurized Pepsin Digestion in Proteomics
- (2010) Daniel López-Ferrer et al. MOLECULAR & CELLULAR PROTEOMICS
- A systematic approach to protein glycosylation analysis: a path through the maze
- (2010) Karina Mariño et al. Nature Chemical Biology
- Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation
- (2010) Zhongqi Zhang et al. PROTEIN SCIENCE
- Conformational changes in oxidatively stressed monoclonal antibodies studied by hydrogen exchange mass spectrometry
- (2010) William Burkitt et al. PROTEIN SCIENCE
- Expansion of time window for mass spectrometric measurement of amide hydrogen/deuterium exchange reactions
- (2010) Stephen J. Coales et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Desulfurization of cysteine-containing peptides resulting from sample preparation for protein characterization by mass spectrometry
- (2010) Zhouxi Wang et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Surrogate H/D Detection Strategy for Protein Conformational Analysis Using MS/MS Data
- (2009) Andrew J. Percy et al. ANALYTICAL CHEMISTRY
- H/D Exchange and Mass Spectrometry in the Studies of Protein Conformation and Dynamics: Is There a Need for a Top-Down Approach?
- (2009) Igor A. Kaltashov et al. ANALYTICAL CHEMISTRY
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- (2009) Erin D. Hopper et al. ANALYTICAL CHEMISTRY
- Characterization of IgG1 Conformation and Conformational Dynamics by Hydrogen/Deuterium Exchange Mass Spectrometry
- (2009) Damian Houde et al. ANALYTICAL CHEMISTRY
- NITPICK: peak identification for mass spectrometry data
- (2009) Bernhard Y Renard et al. BMC BIOINFORMATICS
- Hydra: software for tailored processing of H/D exchange data from MS or tandem MS analyses
- (2009) Gordon W Slysz et al. BMC BIOINFORMATICS
- Effect of Ions on the Structure of Water: Structure Making and Breaking
- (2009) Yizhak Marcus CHEMICAL REVIEWS
- Distinct Structures of Scrapie Prion Protein (PrPSc)-seededVersusSpontaneous Recombinant Prion Protein Fibrils Revealed by Hydrogen/Deuterium Exchange
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- Hydrogen/Deuterium Exchange Mass Spectrometry with Top-Down Electron Capture Dissociation for Characterizing Structural Transitions of a 17 kDa Protein
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- Protein conformations can be probed in top-down HDX MS experiments utilizing electron transfer dissociation of protein ions without hydrogen scrambling
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- Conformation and dynamics of biopharmaceuticals: Transition of mass spectrometry-based tools from academe to industry
- (2009) Igor A. Kaltashov et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Urea, but not guanidinium, destabilizes proteins by forming hydrogen bonds to the peptide group
- (2009) Woon Ki Lim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Recombinant immobilized rhizopuspepsin as a new tool for protein digestion in hydrogen/deuterium exchange mass spectrometry
- (2009) Martial Rey et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Determination of pKaValues of Individual Histidine Residues in Proteins Using Mass Spectrometry
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- Gas-Phase Fragmentation of Peptides by MALDI in-Source Decay with Limited Amide Hydrogen (1H/2H) Scrambling
- (2008) Nicolai Bache et al. ANALYTICAL CHEMISTRY
- Restraining Expansion of the Peak Envelope in H/D Exchange-MS and Its Application in Detecting Perturbations of Protein Structure/Dynamics
- (2008) Gordon W. Slysz et al. ANALYTICAL CHEMISTRY
- A Simple Test To Detect Hydrogen/Deuterium Scrambling during Gas-Phase Peptide Fragmentation
- (2008) Yoshitomo Hamuro et al. ANALYTICAL CHEMISTRY
- Enhanced Digestion Efficiency, Peptide Ionization Efficiency, and Sequence Resolution for Protein Hydrogen/Deuterium Exchange Monitored by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
- (2008) Hui-Min Zhang et al. ANALYTICAL CHEMISTRY
- High-Speed and High-Resolution UPLC Separation at Zero Degrees Celsius
- (2008) Thomas E. Wales et al. ANALYTICAL CHEMISTRY
- Intrinsically Disordered Proteins in Human Diseases: Introducing the D2 Concept
- (2008) Vladimir N. Uversky et al. Annual Review of Biophysics
- A Mass Spectrometric Approach to the Study of DNA-Binding Proteins: Interaction of Human TRF2 with Telomeric DNA†
- (2008) Justin B. Sperry et al. BIOCHEMISTRY
- Interaction of Group IA Phospholipase A2with Metal Ions and Phospholipid Vesicles Probed with Deuterium Exchange Mass Spectrometry†
- (2008) John E. Burke et al. BIOCHEMISTRY
- Monitoring the positioning of short polycationic peptides in model lipid bilayers by combining hydrogen/deuterium exchange and electrospray ionization mass spectrometry
- (2008) Bibiana Monson de Souza et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Hydrogen/deuterium exchange study of subtilisin Carlsberg during prolonged exposure to organic solvents
- (2008) Ezio Fasoli et al. BIOTECHNOLOGY AND BIOENGINEERING
- Structural and Functional Consequences of Tyrosine Phosphorylation in the LRP1 Cytoplasmic Domain
- (2008) Gina N. Betts et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protein structure and dynamics studied by mass spectrometry: H/D exchange, hydroxyl radical labeling, and related approaches
- (2008) Lars Konermann et al. JOURNAL OF MASS SPECTROMETRY
- Application of Pressurized Solvents for Ultrafast Trypsin Hydrolysis in Proteomics: Proteomics on the Fly
- (2008) Daniel López-Ferrer et al. JOURNAL OF PROTEOME RESEARCH
- Electron Capture Dissociation Proceeds with a Low Degree of Intramolecular Migration of Peptide Amide Hydrogens
- (2008) Kasper D. Rand et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Hydrogen Atom Scrambling in Selectively Labeled Anionic Peptides Upon Collisional Activation by MALDI Tandem Time-of-Flight Mass Spectrometry
- (2008) N BACHE et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Fast reversed-phase liquid chromatography to reduce back exchange and increase throughput in H/D exchange monitored by FT-ICR mass spectrometry
- (2008) Hui-Min Zhang et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- HD desktop: An integrated platform for the analysis and visualization of H/D exchange data
- (2008) Bruce D. Pascal et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Effects of electrospray capillary temperature on amide hydrogen exchange
- (2008) Stephen J. Coales et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Assessment of the repeatability and reproducibility of hydrogen/deuterium exchange mass spectrometry measurements
- (2008) William Burkitt et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Ion mobility adds an additional dimension to mass spectrometric analysis of solution-phase hydrogen/deuterium exchange
- (2008) Roxana E. Iacob et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Hydrogen/deuterium exchange on protein solutions containing nucleic acids: utility of protamine sulfate
- (2008) Anton Poliakov et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Specificity of immobilized porcine pepsin in H/D exchange compatible conditions
- (2008) Yoshitomo Hamuro et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Hydrogen exchange and ligand binding: Ligand-dependent and ligand-independent protection in the Src SH3 domain
- (2004) David Wildes et al. PROTEIN SCIENCE
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