Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses

Functional selection of protease inhibitory antibodies

(2019) Tyler Lopez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The life cycle of non-polio enteroviruses and how to target it

(2018) Jim Baggen et al.   NATURE REVIEWS MICROBIOLOGY

Proteases and protease inhibitors in infectious diseases

(2017) Ayodeji A. Agbowuro et al.   MEDICINAL RESEARCH REVIEWS

Potent peptidic fusion inhibitors of influenza virus

(2017) Rameshwar U. Kadam et al.   SCIENCE

Direct-acting antivirals and host-targeting strategies to combat enterovirus infections

(2017) Lisa Bauer et al.   Current Opinion in Virology

Enteroviral proteases: structure, host interactions and pathogenicity

(2016) Olli H. Laitinen et al.   REVIEWS IN MEDICAL VIROLOGY

Long-Range Communication between Different Functional Sites in the Picornaviral 3C Protein

(2016) Yan M. Chan et al.   STRUCTURE

Innate Immunity Evasion by Enteroviruses: Insights into Virus-Host Interaction

(2016) Xiaobo Lei et al.   Viruses-Basel

Rhinovirus in the Pathogenesis and Clinical Course of Asthma

(2015) Kyla C. Jamieson et al.   CHEST

Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation

(2015) Bei Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Replication and Inhibitors of Enteroviruses and Parechoviruses

(2015) Lonneke Linden et al.   Viruses-Basel

Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation

(2015) Bei Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Prevention of Cell Death by Antibodies Selected from Intracellular Combinatorial Libraries

(2014) Jia Xie et al.   CHEMISTRY & BIOLOGY

Allosteric Inactivation of a Trypsin-Like Serine Protease by An Antibody Binding to the 37- and 70-Loops

(2013) Tobias Kromann-Hansen et al.   BIOCHEMISTRY

Human Rhinoviruses

(2013) Samantha E. Jacobs et al.   CLINICAL MICROBIOLOGY REVIEWS

A Monoclonal Antibody (MCPR3-7) Interfering with the Activity of Proteinase 3 by an Allosteric Mechanism

(2013) Lisa C. Hinkofer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Picornavirus and enterovirus diversity with associated human diseases

(2012) Caroline Tapparel et al.   INFECTION GENETICS AND EVOLUTION

A Reverse Binding Motif That Contributes to Specific Protease Inhibition by Antibodies

(2011) Eric L. Schneider et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural and mechanistic insight into how antibodies inhibit serine proteases

(2010) Rajkumar Ganesan et al.   BIOCHEMICAL JOURNAL

Allosteric regulation of protease activity by small molecules

(2010) Aimee Shen   Molecular BioSystems

Unraveling the Allosteric Mechanism of Serine Protease Inhibition by an Antibody

(2009) Rajkumar Ganesan et al.   STRUCTURE

Allosteric Regulation of Proteases

(2008) Patrick Hauske et al.   CHEMBIOCHEM

Structure of an Fab–Protease Complex Reveals a Highly Specific Non-canonical Mechanism of Inhibition

(2008) Christopher J. Farady et al.   JOURNAL OF MOLECULAR BIOLOGY