Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

Identification of B cell epitopes of dengue virus 2 NS3 protein by monoclonal antibody

(2012) Yanping Tian et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Prophylactic and therapeutic efficacy of the epitope vaccine CTB-UA against Helicobacter pylori infection in a BALB/c mice model

(2012) Le Guo et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Structural Insight into the Mechanism of DNA-Binding Attenuation of the Neisserial Adhesin Repressor NadR by the Small Natural Ligand 4-Hydroxyphenylacetic Acid

(2012) Sébastien Brier et al.   BIOCHEMISTRY

Principles for designing ideal protein structures

(2012) Nobuyasu Koga et al.   NATURE

Monoclonal Antibodies to Meningococcal Factor H Binding Protein with Overlapping Epitopes and Discordant Functional Activity

(2012) Serena Giuntini et al.   PLoS One

The new multicomponent vaccine against meningococcal serogroup B, 4CMenB: Immunological, functional and structural characterization of the antigens

(2012) Davide Serruto et al.   VACCINE

Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules

(2012) Steven Johnson et al.   PLoS Pathogens

Structure of the uncomplexedNeisseria meningitidisfactor H-binding protein fHbp (rLP2086)

(2011) Laura Cendron et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Recombinant protein meningococcal serogroup B vaccine combined with outer membrane vesicles

(2011) Xilian Bai et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

New frontiers in meningococcal vaccines

(2011) Annaliesa S Anderson et al.   Expert Review of Vaccines

Early clinical experience with a candidate meningococcal B recombinant vaccine (rMenB) in healthy adults

(2011) Daniela Toneatto et al.   Human vaccines & immunotherapeutics

Complement-Mediated Bactericidal Activity of Anti-Factor H Binding Protein Monoclonal Antibodies against the Meningococcus Relies upon Blocking Factor H Binding

(2011) Serena Giuntini et al.   INFECTION AND IMMUNITY

Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity

(2011) M. Scarselli et al.   Science Translational Medicine

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Characterization of Diverse Subvariants of the Meningococcal Factor H (fH) Binding Protein for Their Ability To Bind fH, To Mediate Serum Resistance, and To Induce Bactericidal Antibodies

(2010) Kate L. Seib et al.   INFECTION AND IMMUNITY

Effect of Factor H-Binding Protein Sequence Variation on Factor H Binding and Survival ofNeisseria meningitidisin Human Blood

(2010) Kathleen Y. Dunphy et al.   INFECTION AND IMMUNITY

Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F

(2010) J. S. McLellan et al.   JOURNAL OF VIROLOGY

Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope

(2010) Bruno E. Correia et al.   STRUCTURE

Solution Structure of the Factor H-binding Protein, a Survival Factor and Protective Antigen ofNeisseria meningitidis

(2009) Francesca Cantini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A region of the N-terminal domain of meningococcal factor H-binding protein that elicits bactericidal antibody across antigenic variant groups

(2009) Peter T. Beernink et al.   MOLECULAR IMMUNOLOGY

Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates

(2009) Muriel C. Schneider et al.   NATURE

Bactericidal Antibody Responses Induced by Meningococcal Recombinant Chimeric Factor H-Binding Protein Vaccines

(2008) P. T. Beernink et al.   INFECTION AND IMMUNITY

Factor H-Binding Protein Is Important for Meningococcal Survival in Human Whole Blood and Serum and in the Presence of the Antimicrobial Peptide LL-37

(2008) K. L. Seib et al.   INFECTION AND IMMUNITY

Structural Basis for the Immunogenic Properties of the Meningococcal Vaccine Candidate LP2086

(2008) Alessandro Mascioni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epitope Mapping of a Bactericidal Monoclonal Antibody against the Factor H Binding Protein of Neisseria meningitidis

(2008) Maria Scarselli et al.   JOURNAL OF MOLECULAR BIOLOGY