The sweet spot for biologics: recent advances in characterization of biotherapeutic glycoproteins
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The sweet spot for biologics: recent advances in characterization of biotherapeutic glycoproteins
Authors
Keywords
-
Journal
Expert Review of Proteomics
Volume 15, Issue 1, Pages 13-29
Publisher
Informa UK Limited
Online
2017-11-13
DOI
10.1080/14789450.2018.1404907
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Aminoquinoline Fluorescent Labels Obstruct Efficient Removal of N-Glycan Core α(1–6) Fucose by Bovine Kidney α-l-Fucosidase (BKF)
- (2017) Róisín O’Flaherty et al. JOURNAL OF PROTEOME RESEARCH
- GingisKHAN™ protease cleavage allows a high-throughput antibody to Fab conversion enabling direct functional assessment during lead identification of human monoclonal and bispecific IgG1 antibodies
- (2017) Jörg Moelleken et al. mAbs
- 2016 FDA drug approvals
- (2017) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Sensitive and comprehensive analysis of O-glycosylation in biotherapeutics: a case study of novel erythropoiesis stimulating protein
- (2017) Unyong Kim et al. Bioanalysis
- Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy
- (2017) Yusuke Mimura et al. Protein & Cell
- Real-Time Analysis on Drug-Antibody Ratio of Antibody-Drug Conjugates for Synthesis, Process Optimization, and Quality Control
- (2017) Yubo Tang et al. Scientific Reports
- Advances in recombinant antibody manufacturing
- (2016) Renate Kunert et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Distinguishing N-acetylneuraminic acid linkage isomers on glycopeptides by ion mobility-mass spectrometry
- (2016) H. Hinneburg et al. CHEMICAL COMMUNICATIONS
- Quantitative profiling of glycans and glycopeptides: an informatics’ perspective
- (2016) Ian Walsh et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- N-glycosylation heterogeneity and the influence on structure, function and pharmacokinetics of monoclonal antibodies and Fc fusion proteins
- (2016) Fabian Higel et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Intact glycopeptide characterization using mass spectrometry
- (2016) Li Cao et al. Expert Review of Proteomics
- Recombinant long-acting glycoPEGylated factor IX (nonacog beta pegol) in haemophilia B: assessment of target joints in multinational phase 3 clinical trials
- (2016) C. Negrier et al. HAEMOPHILIA
- Characterization of immunoglobulins through analysis of N-glycopeptides by MALDI-TOF MS
- (2016) Emy Komatsu et al. METHODS
- Editing of mouse and human immunoglobulin genes by CRISPR-Cas9 system
- (2016) Taek-Chin Cheong et al. Nature Communications
- Fc-Binding Ligands of Immunoglobulin G: An Overview of High Affinity Proteins and Peptides
- (2016) Weonu Choe et al. Materials
- Fractionation of Fab glycosylated immunoglobulin G with concanavalin A chromatography unveils new structural properties of the molecule
- (2016) Tao Huang et al. Oncotarget
- Comparison of procainamide and 2-aminobenzamide labeling for profiling and identification of glycans by liquid chromatography with fluorescence detection coupled to electrospray ionization–mass spectrometry
- (2015) Radoslaw P. Kozak et al. ANALYTICAL BIOCHEMISTRY
- Site-Specific Protein N- and O-Glycosylation Analysis by a C18-Porous Graphitized Carbon–Liquid Chromatography-Electrospray Ionization Mass Spectrometry Approach Using Pronase Treated Glycopeptides
- (2015) Kathrin Stavenhagen et al. ANALYTICAL CHEMISTRY
- Ultrahigh Throughput, Ultrafiltration-Based N-Glycomics Platform for Ultraperformance Liquid Chromatography (ULTRA3)
- (2015) Henning Stöckmann et al. ANALYTICAL CHEMISTRY
- Linkage-Specific Sialic Acid Derivatization for MALDI-TOF-MS Profiling of IgG Glycopeptides
- (2015) Noortje de Haan et al. ANALYTICAL CHEMISTRY
- Rapid Preparation of Released N-Glycans for HILIC Analysis Using a Labeling Reagent that Facilitates Sensitive Fluorescence and ESI-MS Detection
- (2015) Matthew A. Lauber et al. ANALYTICAL CHEMISTRY
- Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis
- (2015) Yoann Rombouts et al. ANNALS OF THE RHEUMATIC DISEASES
- Carbohydrates on Proteins: Site-Specific Glycosylation Analysis by Mass Spectrometry
- (2015) Zhikai Zhu et al. Annual Review of Analytical Chemistry
- High-throughput glycomics: Optimization of sample preparation
- (2015) I. Trbojević Akmačić et al. BIOCHEMISTRY-MOSCOW
- The Diversity of Biosimilar Design and Development: Implications for Policies and Stakeholders
- (2015) Gustavo Grampp et al. BIODRUGS
- Nature of foulants and fouling mechanism in the Protein A MabSelect resin cycled in a monoclonal antibody purification process
- (2015) Shaojie Zhang et al. BIOTECHNOLOGY AND BIOENGINEERING
- Highly specific enrichment of N-glycoproteome through a nonreductive amination reaction using Fe3O4@SiO2-aniline nanoparticles
- (2015) Ying Zhang et al. CHEMICAL COMMUNICATIONS
- Symbol Nomenclature for Graphical Representations of Glycans
- (2015) Ajit Varki et al. GLYCOBIOLOGY
- Automated, high-throughput serum glycoprofiling platform
- (2015) H. Stöckmann et al. Integrative Biology
- A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis
- (2015) Alison E. Mahan et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Automation of High-Throughput Mass Spectrometry-Based Plasma N-Glycome Analysis with Linkage-Specific Sialic Acid Esterification
- (2015) Marco R. Bladergroen et al. JOURNAL OF PROTEOME RESEARCH
- Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles—Part 2: Mass spectrometric methods
- (2015) Dietmar Reusch et al. mAbs
- Glycan analysis of therapeutic glycoproteins
- (2015) Lei Zhang et al. mAbs
- Characterization of a chemically modified plant cell culture expressed human α-Galactosidase-A enzyme for treatment of Fabry disease
- (2015) Tali Kizhner et al. MOLECULAR GENETICS AND METABOLISM
- Highly Selective and Ultra Fast Solid-Phase Extraction of N-Glycoproteome by Oxime Click Chemistry Using Aminooxy-Functionalized Magnetic Nanoparticles
- (2014) Ying Zhang et al. ANALYTICAL CHEMISTRY
- Simple Capillary Electrophoresis–Mass Spectrometry Method for Complex Glycan Analysis Using a Flow-Through Microvial Interface
- (2014) Roxana G. Jayo et al. ANALYTICAL CHEMISTRY
- High-Throughput Profiling of Protein N-Glycosylation by MALDI-TOF-MS Employing Linkage-Specific Sialic Acid Esterification
- (2014) Karli R. Reiding et al. ANALYTICAL CHEMISTRY
- Rapid Magnetic Bead Based Sample Preparation for Automated and High Throughput N-Glycan Analysis of Therapeutic Antibodies
- (2014) Csaba Váradi et al. ANALYTICAL CHEMISTRY
- Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web-based target finding tool
- (2014) Carlotta Ronda et al. BIOTECHNOLOGY AND BIOENGINEERING
- Rapid comparison of a candidate biosimilar to an innovator monoclonal antibody with advanced liquid chromatography and mass spectrometry technologies
- (2014) Hongwei Xie et al. mAbs
- The therapeutic monoclonal antibody market
- (2014) Dawn M Ecker et al. mAbs
- Quantitative mass spectrometric analysis of glycoproteins combined with enrichment methods
- (2014) Yeong Hee Ahn et al. MASS SPECTROMETRY REVIEWS
- Immunoglobulin G (IgG) Fab Glycosylation Analysis Using a New Mass Spectrometric High-throughput Profiling Method Reveals Pregnancy-associated Changes
- (2014) Albert Bondt et al. MOLECULAR & CELLULAR PROTEOMICS
- Comparative Performance of Four Methods for High-throughput Glycosylation Analysis of Immunoglobulin G in Genetic and Epidemiological Research
- (2014) Jennifer E. Huffman et al. MOLECULAR & CELLULAR PROTEOMICS
- Characterization of Intact Neo-Glycoproteins by Hydrophilic Interaction Liquid Chromatography
- (2014) Alice Pedrali et al. MOLECULES
- The power of ion mobility-mass spectrometry for structural characterization and the study of conformational dynamics
- (2014) Francesco Lanucara et al. Nature Chemistry
- Glycoengineering of Interferon-β 1a Improves Its Biophysical and Pharmacokinetic Properties
- (2014) Kyoung Song et al. PLoS One
- Fusion tags for protein solubility, purification and immunogenicity in Escherichia coli: the novel Fh8 system
- (2014) Sofia Costa et al. Frontiers in Microbiology
- Analysis of native and APTS-labeled N-glycans by capillary electrophoresis/time-of-flight mass spectrometry
- (2013) Svenja-Catharina Bunz et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Reversed-phase liquid-chromatographic mass spectrometric N-glycan analysis of biopharmaceuticals
- (2013) Fabian Higel et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Comparison of two approaches for quantitative O-linked glycan analysis used in characterization of recombinant proteins
- (2013) Iva Turyan et al. ANALYTICAL BIOCHEMISTRY
- Unraveling the Glyco-Puzzle: Glycan Structure Identification by Capillary Electrophoresis
- (2013) Stefan Mittermayr et al. ANALYTICAL CHEMISTRY
- Capillary Electrophoresis/Mass Spectrometry of APTS-Labeled Glycans for the Identification of Unknown Glycan Species in Capillary Electrophoresis/Laser-Induced Fluorescence Systems
- (2013) Svenja-Catharina Bunz et al. ANALYTICAL CHEMISTRY
- Automated, High-Throughput IgG-Antibody Glycoprofiling Platform
- (2013) Henning Stöckmann et al. ANALYTICAL CHEMISTRY
- N- and O-Glycosylation Analysis of Etanercept Using Liquid Chromatography and Quadrupole Time-of-Flight Mass Spectrometry Equipped with Electron-Transfer Dissociation Functionality
- (2013) Stephane Houel et al. ANALYTICAL CHEMISTRY
- Validation of the curation pipeline of UniCarb-DB: Building a global glycan reference MS/MS repository
- (2013) Matthew P. Campbell et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Clinical considerations for biosimilar antibodies
- (2013) Håkan Mellstedt EJC SUPPLEMENTS
- Recent advances in mammalian protein production
- (2013) Ashok D. Bandaranayake et al. FEBS LETTERS
- A cost-effective plate-based sample preparation for antibody N-glycan analysis
- (2013) Irina Burnina et al. JOURNAL OF CHROMATOGRAPHY A
- Oriented immobilization of peptide-N-glycosidase F on a monolithic support for glycosylation analysis
- (2013) Jana Krenkova et al. JOURNAL OF CHROMATOGRAPHY A
- Rapid Fc glycosylation analysis of Fc fusions with IdeS and liquid chromatography mass spectrometry
- (2013) Heather Lynaugh et al. mAbs
- Performing native mass spectrometry analysis on therapeutic antibodies
- (2013) Natalie J. Thompson et al. METHODS
- Glycopeptide Analysis, Recent Developments and Applications
- (2013) Heather Desaire MOLECULAR & CELLULAR PROTEOMICS
- Analytical platform for glycomic characterization of recombinant erythropoietin biotherapeutics and biosimilars by MS
- (2013) Myung Jin Oh et al. Bioanalysis
- Preparative Purification of Recombinant Proteins: Current Status and Future Trends
- (2013) Mayank Saraswat et al. Biomed Research International
- Online nanoliquid chromatography–mass spectrometry and nanofluorescence detection for high-resolution quantitative N-glycan analysis
- (2012) Hakan Kalay et al. ANALYTICAL BIOCHEMISTRY
- Detection of N-glycans on small amounts of glycoproteins in tissue samples and sodium dodecyl sulfate–polyacrylamide gels
- (2012) Takeshi Yoshimura et al. ANALYTICAL BIOCHEMISTRY
- PNGase F catalyzes de-N-glycosylation in a domestic microwave
- (2012) Hui Zhou et al. ANALYTICAL BIOCHEMISTRY
- Centrifugation Assisted Microreactor Enables Facile Integration of Trypsin Digestion, Hydrophilic Interaction Chromatography Enrichment, and On-Column Deglycosylation for Rapid and Sensitive N-Glycoproteome Analysis
- (2012) Jun Zhu et al. ANALYTICAL CHEMISTRY
- Fast and Efficient Online Release of N-Glycans from Glycoproteins Facilitating Liquid Chromatography–Tandem Mass Spectrometry Glycomic Profiling
- (2012) Yazen Jmeian et al. ANALYTICAL CHEMISTRY
- GlycoPep Grader: A Web-Based Utility for Assigning the Composition ofN-Linked Glycopeptides
- (2012) Carrie L. Woodin et al. ANALYTICAL CHEMISTRY
- Separation and Identification of Isomeric Glycopeptides by High Field Asymmetric Waveform Ion Mobility Spectrometry
- (2012) Andrew J. Creese et al. ANALYTICAL CHEMISTRY
- CE-MS for the analysis of intact proteins 2010-2012
- (2012) Rob Haselberg et al. ELECTROPHORESIS
- Influence of molecular configuration and conformation on the electromigration of oligosaccharides in narrow bore capillaries
- (2012) Stefan Mittermayr et al. ELECTROPHORESIS
- N-glycosylation of Colorectal Cancer Tissues
- (2012) Crina I. A. Balog et al. MOLECULAR & CELLULAR PROTEOMICS
- Analysis of Intact Monoclonal Antibody IgG1 by Electron Transfer Dissociation Orbitrap FTMS
- (2012) Luca Fornelli et al. MOLECULAR & CELLULAR PROTEOMICS
- High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies
- (2012) Rebecca J Rose et al. NATURE METHODS
- Determination of site-specific glycan heterogeneity on glycoproteins
- (2012) Daniel Kolarich et al. Nature Protocols
- Structural analysis of N- and O-glycans released from glycoproteins
- (2012) Pia H Jensen et al. Nature Protocols
- Vertebrate protein glycosylation: diversity, synthesis and function
- (2012) Kelley W. Moremen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Software for analysing ion mobility mass spectrometry data to improve peptide identification
- (2012) Dong Xia et al. PROTEOMICS
- Characterization of disease-associatedN-linked glycoproteins
- (2012) Yuan Tian et al. PROTEOMICS
- Analysis of recombinant human erythropoietin glycopeptides by capillary electrophoresis electrospray–time of flight-mass spectrometry
- (2011) Estela Giménez et al. ANALYTICA CHIMICA ACTA
- Analysis of recombinant human follicle-stimulating hormone (FSH) by mass spectrometric approaches
- (2011) Josephine Grass et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Fast analysis of recombinant monoclonal antibodies using IdeS proteolytic digestion and electrospray mass spectrometry
- (2011) Guillaume Chevreux et al. ANALYTICAL BIOCHEMISTRY
- Cotton HILIC SPE Microtips for Microscale Purification and Enrichment of Glycans and Glycopeptides
- (2011) Maurice H. J. Selman et al. ANALYTICAL CHEMISTRY
- A promising capillary electrophoresis-electrospray ionization-mass spectrometry method for carbohydrate analysis
- (2011) E. Jane Maxwell et al. ELECTROPHORESIS
- Enhanced sensitivity of LC-MS analysis of permethylated N-glycans through online purification
- (2011) Janie L. Desantos-Garcia et al. ELECTROPHORESIS
- Analytical methods for physicochemical characterization of antibody drug conjugates
- (2011) Aditya Wakankar et al. mAbs
- HILIC analysis of fluorescence-labeled N-glycans from recombinant biopharmaceuticals
- (2010) Michael Melmer et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Chemical and enzymatic N-glycan release comparison for N-glycan profiling of monoclonal antibodies expressed in plants
- (2010) Ada Triguero et al. ANALYTICAL BIOCHEMISTRY
- High Throughput Quantification of N-Glycans Using One-Pot Sialic Acid Modification and Matrix Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry
- (2010) Geun-Cheol Gil et al. ANALYTICAL CHEMISTRY
- Resolving Disulfide Structural Isoforms of IgG2 Monoclonal Antibodies by Ion Mobility Mass Spectrometry
- (2010) Dhanashri Bagal et al. ANALYTICAL CHEMISTRY
- Rapid Release of N-Linked Glycans from Glycoproteins by Pressure-Cycling Technology
- (2010) Zoltan Szabo et al. ANALYTICAL CHEMISTRY
- Mass Spectrometric-Based Stable Isotopic 2-Aminobenzoic Acid Glycan Mapping for Rapid Glycan Screening of Biotherapeutics
- (2010) Justin M. Prien et al. ANALYTICAL CHEMISTRY
- Methylamidation for Sialoglycomics by MALDI-MS: A Facile Derivatization Strategy for Both α2,3- and α2,6-Linked Sialic Acids
- (2010) Xin Liu et al. ANALYTICAL CHEMISTRY
- Skyline: an open source document editor for creating and analyzing targeted proteomics experiments
- (2010) Brendan MacLean et al. BIOINFORMATICS
- Improved sample preparation method for glycan analysis of glycoproteins by CE-LIF and CE-MS
- (2010) Zoltan Szabo et al. ELECTROPHORESIS
- Hydrophilic interaction chromatography of intact, soluble proteins
- (2010) Tim Tetaz et al. JOURNAL OF CHROMATOGRAPHY A
- The evaluation of a novel approach for the profiling and identification of N-linked glycan with a procainamide tag by HPLC with fluorescent and mass spectrometric detection
- (2010) Song Klapoetke et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Optimized Workflow for Preparation of APTS-Labeled N-Glycans Allowing High-Throughput Analysis of Human Plasma Glycomes using 48-Channel Multiplexed CGE-LIF
- (2010) L. Renee Ruhaak et al. JOURNAL OF PROTEOME RESEARCH
- Recovery and purification process development for monoclonal antibody production
- (2010) Hui F. Liu et al. mAbs
- Chinese hamster ovary cells can produce galactose-α-1,3-galactose antigens on proteins
- (2010) Carlos J Bosques et al. NATURE BIOTECHNOLOGY
- A systematic approach to protein glycosylation analysis: a path through the maze
- (2010) Karina Mariño et al. Nature Chemical Biology
- 2-Picoline-borane: A non-toxic reducing agent for oligosaccharide labeling by reductive amination
- (2010) L. Renee Ruhaak et al. PROTEOMICS
- Boronate affinity monolith for highly selective enrichment of glycopeptides and glycoproteins
- (2009) Ming Chen et al. ANALYST
- Determination of glycosylation sites and site-specific heterogeneity in glycoproteins
- (2009) Hyun Joo An et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Optimal and consistent protein glycosylation in mammalian cell culture
- (2009) P. Hossler et al. GLYCOBIOLOGY
- Accelerated digestion for high-throughput proteomics analysis of whole bacterial proteomes
- (2009) Ali R. Vaezzadeh et al. JOURNAL OF MICROBIOLOGICAL METHODS
- Mass measurement and top-down HPLC/MS analysis of intact monoclonal antibodies on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer
- (2009) Pavel V. Bondarenko et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Digestion completeness of microwave-assisted and conventional trypsin-catalyzed reactions
- (2009) P. Muralidhar Reddy et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Comparison of fluorescent labels for oligosaccharides and introduction of a new postlabeling purification method
- (2008) Martin Pabst et al. ANALYTICAL BIOCHEMISTRY
- Hydrophilic Interaction Chromatography-Based High-Throughput Sample Preparation Method for N-Glycan Analysis from Total Human Plasma Glycoproteins
- (2008) L. Renee Ruhaak et al. ANALYTICAL CHEMISTRY
- GlycoBase and autoGU: tools for HPLC-based glycan analysis
- (2008) M. P. Campbell et al. BIOINFORMATICS
- Cetuximab-Induced Anaphylaxis and IgE Specific for Galactose-α-1,3-Galactose
- (2008) Christine H. Chung et al. NEW ENGLAND JOURNAL OF MEDICINE
- Analysis of immunoglobulin glycosylation by LC-ESI-MS of glycopeptides and oligosaccharides
- (2008) Johannes Stadlmann et al. PROTEOMICS
- Recapitulation of IVIG Anti-Inflammatory Activity with a Recombinant IgG Fc
- (2008) R. M. Anthony et al. SCIENCE
- HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software
- (2007) Louise Royle et al. ANALYTICAL BIOCHEMISTRY
- Mucin-type O-glycosylation and its potential use in drug and vaccine development
- (2007) Mads Agervig Tarp et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Two-dimensional hydrophilic interaction chromatography coupling anion-exchange and hydrophilic interaction columns for separation of 2-pyridylamino derivatives of neutral and sialylated N-glycans
- (2007) Kisaburo Deguchi et al. JOURNAL OF CHROMATOGRAPHY A
- Determination of N-glycosylation sites and site heterogeneity in a monoclonal antibody by electrospray quadrupole ion-mobility time-of-flight mass spectrometry
- (2007) Petra Olivova et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started