Hydrogen–deuterium exchange reveals long-range dynamical allostery in soybean lipoxygenase

Hydrogen–Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling

(2017) Adam R. Offenbacher et al.   ACS Central Science

Hydrogen/Deuterium Exchange Kinetics Demonstrate Long Range Allosteric Effects of Thumb Site 2 Inhibitors of Hepatitis C Viral RNA-dependent RNA Polymerase

(2016) Daniel Deredge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Manganese Lipoxygenase of the Rice Blast FungusMagnaporthe oryzae

(2016) Anneli Wennman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis of site-specifically 13 C labeled linoleic acids

(2016) Adam R. Offenbacher et al.   TETRAHEDRON LETTERS

The structural basis for specificity in lipoxygenase catalysis

(2015) Marcia E. Newcomer et al.   PROTEIN SCIENCE

Type 1 and Type 2 scenarios in hydrogen exchange mass spectrometry studies on protein–ligand complexes

(2014) Lars Konermann et al.   ANALYST

Effects of Protein–Ligand Interactions on Hydrogen/Deuterium Exchange Kinetics: Canonical and Noncanonical Scenarios

(2014) Modupeola A. Sowole et al.   ANALYTICAL CHEMISTRY

Extremely Elevated Room-Temperature Kinetic Isotope Effects Quantify the Critical Role of Barrier Width in Enzymatic C–H Activation

(2014) Shenshen Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nitric Oxide-Induced Conformational Changes in Soluble Guanylate Cyclase

(2014) Eric S. Underbakke et al.   STRUCTURE

Kinetic and Structural Investigations into the Allosteric and pH Effect on the Substrate Specificity of Human Epithelial 15-Lipoxygenase-2

(2013) Netra Joshi et al.   BIOCHEMISTRY

Locating a Lipid at the Portal to the Lipoxygenase Active Site

(2012) Betty J. Gaffney et al.   BIOPHYSICAL JOURNAL

Structure of a Calcium-dependent 11R-Lipoxygenase Suggests a Mechanism for Ca2+Regulation

(2012) Priit Eek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HDX Workbench: Software for the Analysis of H/D Exchange MS Data

(2012) Bruce D. Pascal et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

The N-terminal β-barrel domain of mammalian lipoxygenases including mouse 5-lipoxygenase is not essential for catalytic activity and membrane binding but exhibits regulatory functions

(2011) Matthias Walther et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease

(2011) Jesper Z. Haeggström et al.   CHEMICAL REVIEWS

Molecular enzymology of lipoxygenases

(2010) Igor Ivanov et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Hydrogen exchange mass spectrometry for studying protein structure and dynamics

(2010) Lars Konermann et al.   CHEMICAL SOCIETY REVIEWS

Identification of novel families and classification of the C2 domain superfamily elucidate the origin and evolution of membrane targeting activities in eukaryotes

(2010) Dapeng Zhang et al.   GENE

Temperature dependence of protein motions in a thermophilic dihydrofolate reductase and its relationship to catalytic efficiency

(2010) O. A. Oyeyemi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102

(2009) Julia Esser et al.   BIOCHEMICAL JOURNAL

Kinetic and Structural Investigations of the Allosteric Site in Human Epithelial 15-Lipoxygenase-2

(2009) Aaron T. Wecksler et al.   BIOCHEMISTRY

Substrate specificity effects of lipoxygenase products and inhibitors on soybean lipoxygenase-1

(2009) Aaron T. Wecksler et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Location of Inhibitors Bound to Group IVA Phospholipase A2Determined by Molecular Dynamics and Deuterium Exchange Mass Spectrometry

(2009) John E. Burke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lipoxygenases – Structure and reaction mechanism

(2009) Alexandra Andreou et al.   PHYTOCHEMISTRY

Conformational Dynamics of Free and Catalytically Active Thermolysin Are Indistinguishable by Hydrogen/Deuterium Exchange Mass Spectrometry†

(2008) Yu-Hong Liu et al.   BIOCHEMISTRY