Effects of ionic interactions on protein stability prediction using solid-state hydrogen deuterium exchange with mass spectrometry (ssHDX-MS)

Published 2019 View Full Article

Authors

Keywords

monoclonal antibody (mAb), solid-state hydrogen deuterium exchange with mass spectrometry (ssHDX-MS), Design of experiments (DoE), Response surface, Arginine, Histidine, Sucrose, Aggregation

Journal

INTERNATIONAL JOURNAL OF PHARMACEUTICS

Volume 568, Issue -, Pages 118512

Publisher

Elsevier BV

Online

2019-07-10

DOI

10.1016/j.ijpharm.2019.118512

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