Ligand-induced conformational dynamics of theEscherichia coliNa+/H+antiporter NhaA revealed by hydrogen/deuterium exchange mass spectrometry

Conformational dynamics of a neurotransmitter:sodium symporter in a lipid bilayer

(2017) Suraj Adhikary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Removal of N-Linked Glycosylations at Acidic pH by PNGase A Facilitates Hydrogen/Deuterium Exchange Mass Spectrometry Analysis of N-Linked Glycoproteins

(2016) Pernille Foged Jensen et al.   ANALYTICAL CHEMISTRY

Ligand binding and conformational dynamics in a flavin-based electron-bifurcating enzyme complex revealed by Hydrogen-Deuterium Exchange Mass Spectrometry

(2016) Julius K. Demmer et al.   FEBS LETTERS

Elevating the alternating-access model

(2016) Renae M Ryan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters

(2016) Mathieu Coincon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Load-dependent destabilization of the γ-rotor shaft in FOF1ATP synthase revealed by hydrogen/deuterium-exchange mass spectrometry

(2016) Siavash Vahidi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elevating the alternating-access model

(2016) Renae M Ryan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters

(2016) Mathieu Coincon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Ec-NhaA antiporter switches from antagonistic to synergistic antiport upon a single point mutation

(2016) Manish Dwivedi et al.   Scientific Reports

NhaA: A Unique Structural Fold of Secondary Active Transporters

(2015) Etana Padan et al.   ISRAEL JOURNAL OF CHEMISTRY

Simulating the function of sodium/proton antiporters

(2015) Raphael Alhadeff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NhaA antiporter functions using 10 helices, and an additional 2 contribute to assembly/stability

(2015) Etana Padan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Na+-dependent citrate transport from the structure of an asymmetrical CitS dimer

(2015) David Wöhlert et al.   eLife

Applications of Hydrogen/Deuterium Exchange MS from 2012 to 2014

(2014) Gregory F. Pirrone et al.   ANALYTICAL CHEMISTRY

Crystal structure of the sodium–proton antiporter NhaA dimer and new mechanistic insights

(2014) Chiara Lee et al.   JOURNAL OF GENERAL PHYSIOLOGY

Visualization of arrestin recruitment by a G-protein-coupled receptor

(2014) Arun K. Shukla et al.   NATURE

Structure and substrate ion binding in the sodium/proton antiporter PaNhaP

(2014) David Wöhlert et al.   eLife

Common Folds and Transport Mechanisms of Secondary Active Transporters

(2013) Yigong Shi   Annual Review of Biophysics

Functional and structural dynamics of NhaA, a prototype for Na+ and H+ antiporters, which are responsible for Na+ and H+ homeostasis in cells

(2013) Etana Padan   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

How LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transporters

(2013) Aravind Penmatsa et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sodium/hydrogen exchanger NHA2 is critical for insulin secretion in  -cells

(2013) C. Deisl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing protein interactions with hydrogen/deuterium exchange and mass spectrometry—A review

(2012) Andrew J. Percy et al.   ANALYTICA CHIMICA ACTA

A Model-Structure of a Periplasm-facing State of the NhaA Antiporter Suggests the Molecular Underpinnings of pH-induced Conformational Changes

(2012) Maya Schushan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Revealing the Ligand Binding Site of NhaA Na+/H+Antiporter and Its pH Dependence

(2012) Michal Maes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational Dynamics of a Membrane Transport Protein Probed by H/D Exchange and Covalent Labeling: The Glycerol Facilitator

(2012) Yan Pan et al.   JOURNAL OF MOLECULAR BIOLOGY

Conformational changes in NhaA Na+/H+antiporter

(2012) Lena Kozachkov et al.   MOLECULAR MEMBRANE BIOLOGY

Lactose Permease and the Alternating Access Mechanism

(2011) Irina Smirnova et al.   BIOCHEMISTRY

Transport Mechanism and pH Regulation of the Na+/H+Antiporter NhaA fromEscherichia coli

(2011) Thomas Mager et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT

(2011) Nien-Jen Hu et al.   NATURE

Conformational changes in the G protein Gs induced by the β2 adrenergic receptor

(2011) Ka Young Chung et al.   NATURE

Molecular aspects of bacterial pH sensing and homeostasis

(2011) Terry A. Krulwich et al.   NATURE REVIEWS MICROBIOLOGY

Ligand-Dependent Perturbation of the Conformational Ensemble for the GPCR β2 Adrenergic Receptor Revealed by HDX

(2011) Graham M. West et al.   STRUCTURE

Membrane protein structural insights from chemical labeling and mass spectrometry

(2010) Yan Pan et al.   ANALYST

Hydrogen exchange mass spectrometry: what is it and what can it tell us?

(2010) Sean R. Marcsisin et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Dynamics of the β2-Adrenergic G-Protein Coupled Receptor Revealed by Hydrogen−Deuterium Exchange

(2010) Xi Zhang et al.   ANALYTICAL CHEMISTRY

Conformational Analysis of Membrane Proteins in Phospholipid Bilayer Nanodiscs by Hydrogen Exchange Mass Spectrometry

(2010) Christine M. Hebling et al.   ANALYTICAL CHEMISTRY

Model-Guided Mutagenesis Drives Functional Studies of Human NHA2, Implicated in Hypertension

(2010) Maya Schushan et al.   JOURNAL OF MOLECULAR BIOLOGY

The Utility of Hydrogen/Deuterium Exchange Mass Spectrometry in Biopharmaceutical Comparability Studies

(2010) Damian Houde et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation

(2010) Zhongqi Zhang et al.   PROTEIN SCIENCE

Combined computational and biochemical study reveals the importance of electrostatic interactions between the “pH sensor” and the cation binding site of the sodium/proton antiporter NhaA ofEscherichia coli

(2009) Elena Olkhova et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Molecular biology of the myocardial Na+/H+ exchanger

(2008) Larry Fliegel   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Conformations of NhaA, the Na/H Exchanger from Escherichia coli, in the pH-Activated and Ion-Translocating States

(2008) Matthias Appel et al.   JOURNAL OF MOLECULAR BIOLOGY