Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

Conformational analysis of complex protein states by hydrogen/deuterium exchange mass spectrometry (HDX-MS): Challenges and emerging solutions

(2018) Esben Trabjerg et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT

(2018) Patrick S. Merkle et al.   Science Advances

Conformational dynamics of a neurotransmitter:sodium symporter in a lipid bilayer

(2017) Suraj Adhikary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA

(2017) Ian Mitchelle S. de Vera et al.   STRUCTURE

Hybrid Mass Spectrometry Approaches to Determine How L-Histidine Feedback Regulates the Enzyzme MtATP-Phosphoribosyltransferase

(2017) Kamila J. Pacholarz et al.   STRUCTURE

Epitope and Paratope Mapping Reveals Temperature-Dependent Alterations in the Dengue-Antibody Interface

(2017) Xin-Xiang Lim et al.   STRUCTURE

High-fidelity DNA replication in Mycobacterium tuberculosis relies on a trinuclear zinc center

(2017) Soledad Baños-Mateos et al.   Nature Communications

Conformational changes in intact dengue virus reveal serotype-specific expansion

(2017) Xin-Xiang Lim et al.   Nature Communications

Structural disorder and induced folding within two cereal, ABA stress and ripening (ASR) proteins

(2017) Karama Hamdi et al.   Scientific Reports

Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling

(2017) Ralph Adams et al.   Scientific Reports

Hydrogen deuterium exchange mass spectrometry in biopharmaceutical discovery and development – A review

(2016) Bin Deng et al.   ANALYTICA CHIMICA ACTA

Conformational insight into multi-protein signaling assemblies by hydrogen–deuterium exchange mass spectrometry

(2016) Rane A Harrison et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structural Dynamics in Ras and Related Proteins upon Nucleotide Switching

(2016) Rane A. Harrison et al.   JOURNAL OF MOLECULAR BIOLOGY

Allosteric inhibition of antiapoptotic MCL-1

(2016) Susan Lee et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Allosteric inhibition of antiapoptotic MCL-1

(2016) Susan Lee et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Analytical Aspects of Hydrogen Exchange Mass Spectrometry

(2015) John R. Engen et al.   Annual Review of Analytical Chemistry

Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes

(2015) K. Rostislavleva et al.   SCIENCE

Replication in bioanalytical studies with HDX MS: aim as high as possible

(2015) Jamie A Moroco et al.   Bioanalysis

Simple Setup for Gas-Phase H/D Exchange Mass Spectrometry Coupled to Electron Transfer Dissociation and Ion Mobility for Analysis of Polypeptide Structure on a Liquid Chromatographic Time Scale

(2014) Ulrik H. Mistarz et al.   ANALYTICAL CHEMISTRY

Applications of Hydrogen/Deuterium Exchange MS from 2012 to 2014

(2014) Gregory F. Pirrone et al.   ANALYTICAL CHEMISTRY

HDX-MS guided drug discovery: small molecules and biopharmaceuticals

(2014) David P Marciano et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Visualization of arrestin recruitment by a G-protein-coupled receptor

(2014) Arun K. Shukla et al.   NATURE

The nature of protein folding pathways

(2014) S. Walter Englander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of PI4KIII  complexes show simultaneous recruitment of Rab11 and its effectors

(2014) J. E. Burke et al.   SCIENCE

Mass Spec Studio for Integrative Structural Biology

(2014) Martial Rey et al.   STRUCTURE

Analysis of Overlapped and Noisy Hydrogen/Deuterium Exchange Mass Spectra

(2013) Miklos Guttman et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Hydrogen-exchange mass spectrometry for the study of intrinsic disorder in proteins

(2012) Deepa Balasubramaniam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Hydrogen Exchange Mass Spectrometry: Are We Out of the Quicksand?

(2012) Roxana E. Iacob et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

HDX Workbench: Software for the Analysis of H/D Exchange MS Data

(2012) Bruce D. Pascal et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Differential hydrogen/deuterium exchange mass spectrometry analysis of protein–ligand interactions

(2011) Michael J Chalmers et al.   Expert Review of Proteomics

Hydrogen exchange mass spectrometry for studying protein structure and dynamics

(2010) Lars Konermann et al.   CHEMICAL SOCIETY REVIEWS

Discovery and Characterization of the Laulimalide-Microtubule Binding Mode by Mass Shift Perturbation Mapping

(2010) Melissa J. Bennett et al.   CHEMISTRY & BIOLOGY

Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation

(2010) Zhongqi Zhang et al.   PROTEIN SCIENCE

Protein Hydrogen Exchange Measured at Single-Residue Resolution by Electron Transfer Dissociation Mass Spectrometry

(2009) Kasper D. Rand et al.   ANALYTICAL CHEMISTRY

Hydrogen/Deuterium Exchange Mass Spectrometry with Top-Down Electron Capture Dissociation for Characterizing Structural Transitions of a 17 kDa Protein

(2009) Jingxi Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein conformations can be probed in top-down HDX MS experiments utilizing electron transfer dissociation of protein ions without hydrogen scrambling

(2009) Rinat R. Abzalimov et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Determination of pKaValues of Individual Histidine Residues in Proteins Using Mass Spectrometry

(2008) Masaru Miyagi et al.   ANALYTICAL CHEMISTRY

Restraining Expansion of the Peak Envelope in H/D Exchange-MS and Its Application in Detecting Perturbations of Protein Structure/Dynamics

(2008) Gordon W. Slysz et al.   ANALYTICAL CHEMISTRY

Crystal Structure of a Prolactin Receptor Antagonist Bound to the Extracellular Domain of the Prolactin Receptor

(2008) L. Anders Svensson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Electron Capture Dissociation Proceeds with a Low Degree of Intramolecular Migration of Peptide Amide Hydrogens

(2008) Kasper D. Rand et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY