Physical and functional interaction sites in cytoplasmic domains of KCNQ1 and KCNE1 channel subunits

Upgraded molecular models of the human KCNQ1 potassium channel

(2019) Georg Kuenze et al.   PLoS One

A comprehensive structural model for the human KCNQ1/KCNE1 ion channel

(2017) Horia Jalily Hasani et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

KCNE1 and KCNE3 modulate KCNQ1 channels by affecting different gating transitions

(2017) Rene Barro-Soria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unnatural amino acid photo-crosslinking of the IKs channel complex demonstrates a KCNE1:KCNQ1 stoichiometry of up to 4:4

(2016) Christopher I Murray et al.   eLife

PIP2-dependent coupling is prominent in Kv7.1 due to weakened interactions between S4-S5 and S6

(2015) Marina A. Kasimova et al.   Scientific Reports

Long QT mutations at the interface between KCNQ1 helix C and KCNE1 disrupt IKS regulation by PKA and PIP2

(2014) M. Dvir et al.   JOURNAL OF CELL SCIENCE

Structural Basis of a Kv7.1 Potassium Channel Gating Module: Studies of the Intracellular C-Terminal Domain in Complex with Calmodulin

(2014) Dana Sachyani et al.   STRUCTURE

Building KCNQ1/KCNE1 Channel Models and Probing their Interactions by Molecular-Dynamics Simulations

(2013) Yu Xu et al.   BIOPHYSICAL JOURNAL

Kv7.1 ion channels require a lipid to couple voltage sensing to pore opening

(2013) M. A. Zaydman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular ATP binding is required to activate the slowly activating K+ channel IKs

(2013) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Slow Activation Gating in the Cardiac IKs Channel Complex

(2011) Nathalie Strutz-Seebohm et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Hallmarks of Molecular Action of Microtubule Stabilizing Agents

(2011) Marina Khrapunovich-Baine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A State-Dependent Salt-Bridge Interaction Exists across the  /  Intersubunit Interface of the GABAA Receptor

(2011) K. T. Laha et al.   MOLECULAR PHARMACOLOGY

Analysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunits

(2010) Renjian Zheng et al.   BIOCHEMICAL JOURNAL

Mapping Spatial Relationships between Residues in the Ligand-Binding Domain of the 5-Ht3 Receptor Using a Molecular Ruler

(2010) Heather L. Nyce et al.   BIOPHYSICAL JOURNAL

PKA and PKC partially rescue Long QT type 1 phenotype by restoring channel-PIP2interactions

(2010) Alessandra Matavel et al.   Channels

Characterization of a Binding Site for Anionic Phospholipids on KCNQ1

(2010) Alison M. Thomas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a protein–protein interaction between KCNE1 and the activation gate machinery of KCNQ1

(2010) Anatoli Lvov et al.   JOURNAL OF GENERAL PHYSIOLOGY

Stoichiometry of the KCNQ1 - KCNE1 ion channel complex

(2010) K. Nakajo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation

(2010) Zhongqi Zhang et al.   PROTEIN SCIENCE

Distinct Pose of Discodermolide in Taxol Binding Pocket Drives a Complementary Mode of Microtubule Stabilization

(2009) Marina Khrapunovich-Baine et al.   BIOCHEMISTRY

Biophysical Properties of 9 KCNQ1 Mutations Associated With Long-QT Syndrome

(2009) Tao Yang et al.   Circulation-Arrhythmia and Electrophysiology

Intracellular domains interactions and gated motions of IKS potassium channel subunits

(2009) Yoni Haitin et al.   EMBO JOURNAL

Functional Interactions between KCNE1 C-Terminus and the KCNQ1 Channel

(2009) Jerri Chen et al.   PLoS One

Location of KCNE1 relative to KCNQ1 in the IKS potassium channel by disulfide cross-linking of substituted cysteines

(2009) David Y. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of KCNE1 and Implications for How It Modulates the KCNQ1 Potassium Channel†‡

(2008) Congbao Kang et al.   BIOCHEMISTRY

An Intersubunit Hydrogen Bond in the Nicotinic Acetylcholine Receptor That Contributes to Channel Gating

(2008) Kristin Rule Gleitsman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

KCNQ1 and KCNE1 in the IKsChannel Complex Make State-dependent Contacts in their Extracellular Domains

(2008) Xulin Xu et al.   JOURNAL OF GENERAL PHYSIOLOGY

Second coiled-coil domain of KCNQ channel controls current expression and subfamily specific heteromultimerization by salt bridge networks

(2008) Koichi Nakajo et al.   JOURNAL OF PHYSIOLOGY-LONDON

A conserved salt bridge critical for GABAA receptor function and loop C dynamics

(2008) S. P. Venkatachalan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA