Cleavage of IgGs by proteases associated with invasive diseases

Human Anti-IgG1 Hinge Autoantibodies Reconstitute the Effector Functions of Proteolytically Inactivated IgGs

(2014) R. J. Brezski et al.   JOURNAL OF IMMUNOLOGY

Antibodies to watch in 2010

(2010) Janice M. Reichert   mAbs

Optimization of Fc-mediated effector functions of monoclonal antibodies

(2009) William R Strohl   CURRENT OPINION IN BIOTECHNOLOGY

Human IgG1 Hinge Fragmentation as the Result of H2O2-mediated Radical Cleavage

(2009) Boxu Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impact of FcγRIIa-FcγRIIIa Polymorphisms and KRAS Mutations on the Clinical Outcome of Patients With Metastatic Colorectal Cancer Treated With Cetuximab Plus Irinotecan

(2009) Frédéric Bibeau et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumor-associated and microbial proteases compromise host IgG effector functions by a single cleavage proximal to the hinge

(2009) R. J. Brezski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-Associated MICA Is Shed by ADAM Proteases

(2008) I. Waldhauer et al.   CANCER RESEARCH

Immunoglobulin G Fragment C Receptor Polymorphisms and Clinical Efficacy of Trastuzumab-Based Therapy in Patients With HER-2/neu–Positive Metastatic Breast Cancer

(2008) Antonino Musolino et al.   JOURNAL OF CLINICAL ONCOLOGY

Human F(ab′)2-containing immune complexes together with anti-hinge natural antibodies stimulate complement amplification in vitro and in vivo

(2008) Sandra Fumia et al.   MOLECULAR IMMUNOLOGY

Proteolysis of purified IgGs by human and bacterial enzymes in vitro and the detection of specific proteolytic fragments of endogenous IgG in rheumatoid synovial fluid

(2007) Mary H. Ryan et al.   MOLECULAR IMMUNOLOGY