Post-HDX Deglycosylation of Fc Gamma Receptor IIIa Glycoprotein Enables HDX Characterization of Its Binding Interface with IgG

Epitope and Paratope Mapping of PD-1/Nivolumab by Mass Spectrometry-based Hydrogen/Deuterium Exchange, Cross-linking, and Molecular Docking

(2020) Mengru Mira Zhang et al.   ANALYTICAL CHEMISTRY

Protein Glycoengineering: An Approach for Improving Protein Properties

(2020) Bo Ma et al.   Frontiers in Chemistry

Deglycosylation by the Acidic Glycosidase PNGase H+ Enables Analysis of N-Linked Glycoproteins by Hydrogen/Deuterium Exchange Mass Spectrometry

(2020) Gerard Comamala et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Glycosylation in health and disease

(2019) Colin Reily et al.   Nature Reviews Nephrology

Recognition of Human IgG1 by Fcγ Receptors: Structural Insights from Hydrogen–Deuterium Exchange and Fast Photochemical Oxidation of Proteins Coupled with Mass Spectrometry

(2019) Liuqing Shi et al.   BIOCHEMISTRY

Hepatitis B Virus X Protein Function Requires Zinc Binding

(2019) Dhivya Ramakrishnan et al.   JOURNAL OF VIROLOGY

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

(2019) Glenn R. Masson et al.   NATURE METHODS

Altered Cell Adhesion and Glycosylation Promote Cancer Immune Suppression and Metastasis

(2019) Heinz Läubli et al.   Frontiers in Immunology

Hydrogen-Deuterium Exchange and Hydroxyl Radical Footprinting for Mapping Hydrophobic Interactions of Human Bromodomain with a Small Molecule Inhibitor

(2019) Ke Sherry Li et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

The Fab portion of immunoglobulin G contributes to its binding to Fcγ receptor III

(2019) Rina Yogo et al.   Scientific Reports

Protein Footprinting and X-ray Crystallography Reveal the Interaction of PD-L1 and a Macrocyclic Peptide

(2019) Ben Niu et al.   BIOCHEMISTRY

Don’t sugarcoat it: How glycocalyx composition influences cancer progression

(2019) Alexander Buffone et al.   JOURNAL OF CELL BIOLOGY

Site-specific N-glycan Analysis of Antibody-binding Fc γ Receptors from Primary Human Monocytes

(2019) Jacob T. Roberts et al.   MOLECULAR & CELLULAR PROTEOMICS

Mapping the Binding Interface of VEGF and a Monoclonal Antibody Fab-1 Fragment with Fast Photochemical Oxidation of Proteins (FPOP) and Mass Spectrometry

(2017) Ying Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Identification of Fc Gamma Receptor Glycoforms That Produce Differential Binding Kinetics for Rituximab

(2017) Jerrard M. Hayes et al.   MOLECULAR & CELLULAR PROTEOMICS

Removal of N-Linked Glycosylations at Acidic pH by PNGase A Facilitates Hydrogen/Deuterium Exchange Mass Spectrometry Analysis of N-Linked Glycoproteins

(2016) Pernille Foged Jensen et al.   ANALYTICAL CHEMISTRY

Biological roles of glycans

(2016) Ajit Varki   GLYCOBIOLOGY

Native MS and ECD Characterization of a Fab–Antigen Complex May Facilitate Crystallization for X-ray Diffraction

(2016) Ying Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

A Perspective on the Structure and Receptor Binding Properties of Immunoglobulin G Fc

(2015) Quinlin M. Hanson et al.   BIOCHEMISTRY

Structure of FcγRI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding

(2015) Jinghua Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fc Gamma Receptor Glycosylation Modulates the Binding of IgG Glycoforms: A Requirement for Stable Antibody Interactions

(2014) Jerrard M. Hayes et al.   JOURNAL OF PROTEOME RESEARCH

Fast Photochemical Oxidation of Proteins (FPOP) Maps the Epitope of EGFR Binding to Adnectin

(2014) Yuetian Yan et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

An Improved Fast Photochemical Oxidation of Proteins (FPOP) Platform for Protein Therapeutics

(2014) Ying Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

N-Linked Glycan Structures of the Human Fcγ Receptors Produced in NS0 Cells

(2013) Eoin F. J. Cosgrave et al.   JOURNAL OF PROTEOME RESEARCH

Complementary MS Methods Assist Conformational Characterization of Antibodies with Altered S–S Bonding Networks

(2013) Lisa M. Jones et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Minimizing Back Exchange in the Hydrogen Exchange-Mass Spectrometry Experiment

(2012) Benjamin T. Walters et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Tracking Hydrogen/Deuterium Exchange at Glycan Sites in Glycoproteins by Mass Spectrometry

(2011) M. Guttman et al.   ANALYTICAL CHEMISTRY

Fast Photochemical Oxidation of Proteins for Epitope Mapping

(2011) Lisa M. Jones et al.   ANALYTICAL CHEMISTRY

Differential hydrogen/deuterium exchange mass spectrometry analysis of protein–ligand interactions

(2011) Michael J Chalmers et al.   Expert Review of Proteomics

Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans

(2011) Tsunehiro Mizushima et al.   GENES TO CELLS

Cell Type-Specific and Site DirectedN-Glycosylation Pattern of FcγRIIIa

(2011) Anne Zeck et al.   JOURNAL OF PROTEOME RESEARCH

Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose

(2011) C. Ferrara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Post-translational Modifications Differentially Affect IgG1 Conformation and Receptor Binding

(2010) Damian Houde et al.   MOLECULAR & CELLULAR PROTEOMICS

Rituximab: Mechanism of Action

(2010) George J. Weiner   SEMINARS IN HEMATOLOGY