The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain

Severe hypertriglyceridemia in a patient heterozygous for a lipoprotein lipase gene allele with two novel missense variants

(2015) Ursula Kassner et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Evidence for Two Distinct Binding Sites for Lipoprotein Lipase on Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1)

(2015) Mart Reimund et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A 3-day-old neonate with severe hypertriglyceridemia from novel mutations of the GPIHBP1 gene

(2015) Paola Sabrina Buonuomo et al.   Journal of Clinical Lipidology

JCL Roundtable: Hypertriglyceridemia due to defects in lipoprotein lipase function

(2015) W. Virgil Brown et al.   Journal of Clinical Lipidology

Stabilizing a Flexible Interdomain Hinge Region Harboring the SMB Binding Site Drives uPAR into Its Closed Conformation

(2015) Baoyu Zhao et al.   JOURNAL OF MOLECULAR BIOLOGY

Chylomicronaemia—current diagnosis and future therapies

(2015) Amanda J. Brahm et al.   Nature Reviews Endocrinology

A new monoclonal antibody, 4-1a, that binds to the amino terminus of human lipoprotein lipase

(2014) André Bensadoun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

DISOPRED3: precise disordered region predictions with annotated protein-binding activity

(2014) David T. Jones et al.   BIOINFORMATICS

The GPIHBP1–LPL Complex Is Responsible for the Margination of Triglyceride-Rich Lipoproteins in Capillaries

(2014) Chris N. Goulbourne et al.   Cell Metabolism

Multimerization of Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1) and Familial Chylomicronemia from a Serine-to-Cysteine Substitution in GPIHBP1 Ly6 Domain

(2014) Wanee Plengpanich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroScale Thermophoresis: Interaction analysis and beyond

(2014) Moran Jerabek-Willemsen et al.   JOURNAL OF MOLECULAR STRUCTURE

Probing the structure of human protein disulfide isomerase by chemical cross-linking combined with mass spectrometry

(2014) Li Peng et al.   Journal of Proteomics

Fixed charges in the gel matrix of sensor chips and dissociation in diffusion gradients influence the detection of fast protein–protein interactions

(2013) Ralf W. Glaser et al.   BIOSYSTEMS

Biochemistry and pathophysiology of intravascular and intracellular lipolysis

(2013) S. G. Young et al.   GENES & DEVELOPMENT

Apolipoproteins C-I and C-III Inhibit Lipoprotein Lipase Activity by Displacement of the Enzyme from Lipid Droplets

(2013) Mikael Larsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Urokinase Receptor Homolog Haldisin Is a Novel Differentiation Marker of Stratum Granulosum in Squamous Epithelia

(2013) Henrik Gårdsvoll et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Chylomicronemia mutations yield new insights into interactions between lipoprotein lipase and GPIHBP1

(2012) Peter Gin et al.   HUMAN MOLECULAR GENETICS

A Flexible Multidomain Structure Drives the Function of the Urokinase-type Plasminogen Activator Receptor (uPAR)

(2012) Haydyn D. T. Mertens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations inLPL,APOC2,APOA5,GPIHBP1andLMF1in patients with severe hypertriglyceridaemia

(2012) R. P. Surendran et al.   JOURNAL OF INTERNAL MEDICINE

Crystal Structure of the Urokinase Receptor in a Ligand-Free Form

(2012) Xiang Xu et al.   JOURNAL OF MOLECULAR BIOLOGY

Rational Targeting of the Urokinase Receptor (uPAR): Development of Antagonists and Non-Invasive Imaging Probes

(2011) M. C. Kriegbaum et al.   CURRENT DRUG TARGETS

Assessing the Role of the Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1) Three-finger Domain in Binding Lipoprotein Lipase

(2011) Anne P. Beigneux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational Regulation of Urokinase Receptor Function

(2011) Henrik Gårdsvoll et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of GPIHBP1 causing severe chylomicronemia

(2011) Jonathan J. Rios et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1

(2011) C. V. Voss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GPIHBP1 Is Responsible for the Entry of Lipoprotein Lipase into Capillaries

(2010) Brandon S.J. Davies et al.   Cell Metabolism

Structure-based Engineering of Species Selectivity in the Interaction between Urokinase and Its Receptor

(2010) Lin Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chylomicronemia With a Mutant GPIHBP1 (Q115P) That Cannot Bind Lipoprotein Lipase

(2009) Anne P. Beigneux et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia

(2009) Gunilla Olivecrona et al.   JOURNAL OF LIPID RESEARCH

The Acidic Domain of GPIHBP1 Is Important for the Binding of Lipoprotein Lipase and Chylomicrons

(2008) Peter Gin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY