Hydrogen-Deuterium Exchange Mass Spectrometry as an Emerging Analytical Tool for Stabilization and Formulation Development of Therapeutic Monoclonal Antibodies

Title
Hydrogen-Deuterium Exchange Mass Spectrometry as an Emerging Analytical Tool for Stabilization and Formulation Development of Therapeutic Monoclonal Antibodies
Authors
Keywords
mass spectrometry, IgG antibody, monoclonal antibody, protein, formulation, protein aggregation, physical stability, physical, characterization, molecular dynamics, chemical stability, excipients
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 104, Issue 2, Pages 327-345
Publisher
Elsevier BV
Online
2014-10-30
DOI
10.1002/jps.24224

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