Structural Implications for the Formation and Function of the Complement Effector Protein iC3b

Regulators of complement activity mediate inhibitory mechanisms through a common C3b‐binding mode

(2016) Federico Forneris et al.   EMBO JOURNAL

Complement component C3 - The “Swiss Army Knife” of innate immunity and host defense

(2016) Daniel Ricklin et al.   IMMUNOLOGICAL REVIEWS

Structural insights on complement activation

(2015) Martín Alcorlo et al.   FEBS Journal

A Revised Mechanism for the Activation of Complement C3 to C3b

(2014) Elizabeth Rodriguez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rational Engineering of a Minimized Immune Inhibitor with Unique Triple-Targeting Properties

(2013) C. Q. Schmidt et al.   JOURNAL OF IMMUNOLOGY

Structural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3

(2013) G. Bajic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A cross-platform toolkit for mass spectrometry and proteomics

(2012) Matthew C Chambers et al.   NATURE BIOTECHNOLOGY

Molecular basis for complement recognition by integrin  X 2

(2012) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg

(2012) Goran Bajic et al.   PROTEIN SCIENCE

The complotype: dictating risk for inflammation and infection

(2012) Claire L. Harris et al.   TRENDS IN IMMUNOLOGY

Unique structure of iC3b resolved at a resolution of 24 Å by 3D-electron microscopy

(2011) Martin Alcorlo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for complement factor I control and its disease-associated sequence polymorphisms

(2011) P. Roversi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Crystal Structure of the Complex Between Human Complement Receptor 2 and Its Ligand C3d

(2011) J. M. H. van den Elsen et al.   SCIENCE

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Allosteric inhibition of complement function by a staphylococcal immune evasion protein

(2010) Hui Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of C3b in Complex with Factors B and D Give Insight into Complement Convertase Formation

(2010) F. Forneris et al.   SCIENCE

Two conformational forms of target-bound iC3b that distinctively bind complement receptors 1 and 2 and two specific monoclonal antibodies

(2010) Ulf R. Nilsson et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

A Molecular Insight into Complement Evasion by the Staphylococcal Complement Inhibitor Protein Family

(2009) D. Ricklin et al.   JOURNAL OF IMMUNOLOGY

Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor

(2009) Suzan H M Rooijakkers et al.   NATURE IMMUNOLOGY

Structure of complement fragment C3b–factor H and implications for host protection by complement regulators

(2009) Jin Wu et al.   NATURE IMMUNOLOGY

Helical structure and stability in human apolipoprotein A-I by hydrogen exchange and mass spectrometry

(2009) Palaniappan Sevugan Chetty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic structural changes during complement C3 activation analyzed by hydrogen/deuterium exchange mass spectrometry

(2008) Michael C. Schuster et al.   MOLECULAR IMMUNOLOGY

Electrostatic contributions drive the interaction betweenStaphylococcus aureusprotein Efb-C and its complement target C3d

(2008) Nurit Haspel et al.   PROTEIN SCIENCE