Structural and biophysical characterizations of HIV-1 matrix trimer binding to lipid nanodiscs shed light on virus assembly

Analysis of HIV-1 matrix-envelope cytoplasmic tail interactions

(2019) Ayna Alfadhli et al.   JOURNAL OF VIROLOGY

Structural basis for targeting avian sarcoma virus Gag polyprotein to the plasma membrane for virus assembly

(2018) Jiri Vlach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assembly of phospholipid nanodiscs of controlled size for structural studies of membrane proteins by NMR

(2017) Franz Hagn et al.   Nature Protocols

Solution Structure and Membrane Interaction of the Cytoplasmic Tail of HIV-1 gp41 Protein

(2017) R. Elliot Murphy et al.   STRUCTURE

Synchronized HIV assembly by tunable PIP2 changes reveals PIP2 requirement for stable Gag anchoring

(2017) Frauke Mücksch et al.   eLife

Conformational modulation of influenza virus hemagglutinin: characterization and in vivo efficacy of monomeric form

(2017) Jong Hyeon Seok et al.   Scientific Reports

The Interplay between Calmodulin and Membrane Interactions with the Pleckstrin Homology Domain of Akt

(2016) Constance Agamasu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Molecular Determinants of Membrane Binding by the HIV-1 Matrix Protein

(2016) Peter Y. Mercredi et al.   JOURNAL OF MOLECULAR BIOLOGY

Membrane Binding of HIV-1 Matrix Protein: Dependence on Bilayer Composition and Protein Lipidation

(2016) Marilia Barros et al.   JOURNAL OF VIROLOGY

Trimer Enhancement Mutation Effects on HIV-1 Matrix Protein Binding Activities

(2016) Ayna Alfadhli et al.   JOURNAL OF VIROLOGY

Nanodiscs for structural and functional studies of membrane proteins

(2016) Ilia G Denisov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Antibody-Based Affinity Cryoelectron Microscopy at 2.6-Å Resolution

(2016) Guimei Yu et al.   STRUCTURE

Nanodiscs for structural and functional studies of membrane proteins

(2016) Ilia G Denisov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Insights into the molecular recognition of the granuphilin C2A domain with PI(4,5)P2

(2015) Chanjuan Wan et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Structural and Biophysical Characterization of the Interactions between Calmodulin and the Pleckstrin Homology Domain of Akt

(2015) Constance Agamasu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Live-cell observation of cytosolic HIV-1 assembly onset reveals RNA-interacting Gag oligomers

(2015) Jelle Hendrix et al.   JOURNAL OF CELL BIOLOGY

HIV-1 assembly, release and maturation

(2015) Eric O. Freed   NATURE REVIEWS MICROBIOLOGY

Biochemical evidence of a role for matrix trimerization in HIV-1 envelope glycoprotein incorporation

(2015) Philip R. Tedbury et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NMR Structure of the Myristylated Feline Immunodeficiency Virus Matrix Protein

(2015) Lola Brown et al.   Viruses-Basel

Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution

(2014) Florian K. M. Schur et al.   NATURE

The role of matrix in HIV-1 envelope glycoprotein incorporation

(2014) Philip R. Tedbury et al.   TRENDS IN MICROBIOLOGY

Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins

(2013) Franz Hagn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evidence in Support of RNA-Mediated Inhibition of Phosphatidylserine-Dependent HIV-1 Gag Membrane Binding in Cells

(2013) V. Chukkapalli et al.   JOURNAL OF VIROLOGY

Effect of Multimerization on Membrane Association of Rous Sarcoma Virus and HIV-1 Matrix Domain Proteins

(2013) R. A. Dick et al.   JOURNAL OF VIROLOGY

Production and stabilization of the trimeric influenza hemagglutinin stem domain for potentially broadly protective influenza vaccines

(2013) Y. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trio engagement via plasma membrane phospholipids and the myristoyl moiety governs HIV-1 matrix binding to bilayers

(2013) Jiri Vlach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Rescue of Defects in HIV-1 Envelope Glycoprotein Incorporation: Implications for Matrix Structure

(2013) Philip R. Tedbury et al.   PLoS Pathogens

NMR Analyses of the Interaction between the FYVE Domain of Early Endosome Antigen 1 (EEA1) and Phosphoinositide Embedded in a Lipid Bilayer

(2012) Mariko Yokogawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Structure of Myristoylated Mason-Pfizer Monkey Virus Matrix Protein and the Role of Phosphatidylinositol-(4,5)-Bisphosphate in Its Membrane Binding

(2012) Jan Prchal et al.   JOURNAL OF MOLECULAR BIOLOGY

HIV-1 Gag protein can sense the cholesterol and acyl chain environment in model membranes

(2012) R. A. Dick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Avogadro: an advanced semantic chemical editor, visualization, and analysis platform

(2012) Marcus D Hanwell et al.   Journal of Cheminformatics

Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly

(2012) Ruba H. Ghanam et al.   Frontiers in Microbiology

Hydrogen/Deuterium Exchange and Electron-Transfer Dissociation Mass Spectrometry Determine the Interface and Dynamics of Apolipoprotein E Oligomerization

(2011) Richard Y-C. Huang et al.   BIOCHEMISTRY

Antibody fragments as tools in crystallography

(2011) L. Griffin et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

NMR, Biophysical, and Biochemical Studies Reveal the Minimal Calmodulin Binding Domain of the HIV-1 Matrix Protein

(2011) Alexandra B. Samal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Determinants that Regulate Plasma Membrane Association of HIV-1 Gag

(2011) Vineela Chukkapalli et al.   JOURNAL OF MOLECULAR BIOLOGY

Rapid identification of recombinant Fabs that bind to membrane proteins

(2011) JungMin Kim et al.   METHODS

Phosphoinositide-incorporated lipid–protein nanodiscs: A tool for studying protein–lipid interactions

(2010) Yoshihiro Kobashigawa et al.   ANALYTICAL BIOCHEMISTRY

Highly Sensitive Analysis of the Interaction between HIV-1 Gag and Phosphoinositide Derivatives Based on Surface Plasmon Resonance

(2010) Kensaku Anraku et al.   BIOCHEMISTRY

Myristate Exposure in the Human Immunodeficiency Virus Type 1 Matrix Protein Is Modulated by pH

(2010) Emily L. Fledderman et al.   BIOCHEMISTRY

Hydrogen exchange mass spectrometry for studying protein structure and dynamics

(2010) Lars Konermann et al.   CHEMICAL SOCIETY REVIEWS

Opposing mechanisms involving RNA and lipids regulate HIV-1 Gag membrane binding through the highly basic region of the matrix domain

(2010) V. Chukkapalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphoinositides Direct Equine Infectious Anemia Virus Gag Trafficking and Release

(2010) Fiona Fernandes et al.   TRAFFIC

The nanodisc: a novel tool for membrane protein studies

(2009) Jonas Borch et al.   BIOLOGICAL CHEMISTRY

Membrane protein assembly into Nanodiscs

(2009) Timothy H. Bayburt et al.   FEBS LETTERS

Analysis of Human Immunodeficiency Virus Type 1 Matrix Binding to Membranes and Nucleic Acids

(2009) A. Alfadhli et al.   JOURNAL OF VIROLOGY

Targeting of Murine Leukemia Virus Gag to the Plasma Membrane Is Mediated by PI(4,5)P2/PS and a Polybasic Region in the Matrix

(2009) E. Hamard-Peron et al.   JOURNAL OF VIROLOGY

Domain Swapping and Different Oligomeric States for the Complex Between Calmodulin and the Calmodulin-Binding Domain of Calcineurin A

(2009) Viivi Majava et al.   PLoS One

Structure and assembly of immature HIV

(2009) J. A. G. Briggs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 matrix organizes as a hexamer of trimers on membranes containing phosphatidylinositol-(4,5)-bisphosphate

(2009) Ayna Alfadhli et al.   VIROLOGY

Three-Dimensional Analysis of Budding Sites and Released Virus Suggests a Revised Model for HIV-1 Morphogenesis

(2008) Lars-Anders Carlson et al.   Cell Host & Microbe

The structural biology of HIV assembly

(2008) Barbie K Ganser-Pornillos et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structure of the Myristylated Human Immunodeficiency Virus Type 2 Matrix Protein and the Role of Phosphatidylinositol-(4,5)-Bisphosphate in Membrane Targeting

(2008) Jamil S. Saad et al.   JOURNAL OF MOLECULAR BIOLOGY

Real-Time Visualization of HIV-1 GAG Trafficking in Infected Macrophages

(2008) Karine Gousset et al.   PLoS Pathogens

Modern analytical ultracentrifugation in protein science: A tutorial review

(2002) Jacob Lebowitz et al.   PROTEIN SCIENCE