Conformational Analysis of Proteins in Highly Concentrated Solutions by Dialysis-Coupled Hydrogen/Deuterium Exchange Mass Spectrometry

Analytical Aspects of Hydrogen Exchange Mass Spectrometry

(2015) John R. Engen et al.   Annual Review of Analytical Chemistry

Hydrogen exchange mass spectrometry reveals protein interfaces and distant dynamic coupling effects during the reversible self-association of an IgG1 monoclonal antibody

(2015) Jayant Arora et al.   mAbs

Dissecting the Binding Mode of Low Affinity Phage Display Peptide Ligands to Protein Targets by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry

(2014) Ulrike Leurs et al.   ANALYTICAL CHEMISTRY

Viscosity of high concentration protein formulations of monoclonal antibodies of the IgG1 and IgG4 subclass – Prediction of viscosity through protein–protein interaction measurements

(2013) Martin S. Neergaard et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Recent advances and further challenges in lyophilization

(2013) Julia Christina Kasper et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Correlating Excipient Effects on Conformational and Storage Stability of an IgG1 Monoclonal Antibody with Local Dynamics as Measured by Hydrogen/Deuterium-Exchange Mass Spectrometry

(2013) Prakash Manikwar et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Therapeutic Antibodies Against Cancer

(2012) Mark J. Adler et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

False EX1 signatures caused by sample carryover during HX MS analyses

(2010) Jing Fang et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Ligand docking and binding site analysis with PyMOL and Autodock/Vina

(2010) Daniel Seeliger et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Factors Affecting the Viscosity in High Concentration Solutions of Different Monoclonal Antibodies

(2010) Sandeep Yadav et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The Utility of Hydrogen/Deuterium Exchange Mass Spectrometry in Biopharmaceutical Comparability Studies

(2010) Damian Houde et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Therapeutic antibodies: successes, limitations and hopes for the future

(2009) Patrick Chames et al.   BRITISH JOURNAL OF PHARMACOLOGY

Silicone Oil- and Agitation-Induced Aggregation of a Monoclonal Antibody in Aqueous Solution

(2009) Renuka Thirumangalathu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Urea, but not guanidinium, destabilizes proteins by forming hydrogen bonds to the peptide group

(2009) Woon Ki Lim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of Ions on Agitation- and Temperature-Induced Aggregation Reactions of Antibodies

(2008) R. Matthew Fesinmeyer et al.   PHARMACEUTICAL RESEARCH