Hydrogen deuterium exchange reveals changes to protein dynamics of recombinant human erythropoietin upon N- and O- desialylation

Published 2018 View Full Article

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Title
Hydrogen deuterium exchange reveals changes to protein dynamics of recombinant human erythropoietin upon N- and O- desialylation
Authors
Keywords
Hydrogen deuterium exchange, EPO, Sialylation, Conformational change, Glycoprotein therapeutics
Journal
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Volume 154, Issue -, Pages 454-459
Publisher
Elsevier BV
Online
2018-03-17
DOI
10.1016/j.jpba.2018.02.060

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