Effects of drying method and excipient on structure and stability of protein solids using solid-state hydrogen/deuterium exchange mass spectrometry (ssHDX-MS)

Title
Effects of drying method and excipient on structure and stability of protein solids using solid-state hydrogen/deuterium exchange mass spectrometry (ssHDX-MS)
Authors
Keywords
Lyophilization, Spray-drying, Protein structure, Biopharmaceutical processing, Formulation, Solid-state hydrogen/deuterium exchange with mass spectrometric analysis (ssHDX-MS)
Journal
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Volume 567, Issue -, Pages 118470
Publisher
Elsevier BV
Online
2019-06-26
DOI
10.1016/j.ijpharm.2019.118470

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