Online Hydrogen-Deuterium Exchange Traveling Wave Ion Mobility Mass Spectrometry (HDX-IM-MS): a Systematic Evaluation

Understanding the Impact of Methionine Oxidation on the Biological Functions of IgG1 Antibodies Using Hydrogen/Deuterium Exchange Mass Spectrometry

(2016) Jingjie Mo et al.   ANALYTICAL CHEMISTRY

MEMHDX: An interactive tool to expedite the statistical validation and visualization of large HDX-MS datasets

(2016) Véronique Hourdel et al.   BIOINFORMATICS

Multi-mode acquisition (MMA): An MS/MS acquisition strategy for maximizing selectivity, specificity and sensitivity of DIA product ion spectra

(2016) Brad J. Williams et al.   PROTEOMICS

Enhanced Detection of Low-Abundance Host Cell Protein Impurities in High-Purity Monoclonal Antibodies Down to 1 ppm Using Ion Mobility Mass Spectrometry Coupled with Multidimensional Liquid Chromatography

(2015) Catalin E. Doneanu et al.   ANALYTICAL CHEMISTRY

Online Deuterium Hydrogen Exchange and Protein Digestion Coupled with Ion Mobility Spectrometry and Tandem Mass Spectrometry

(2015) Gregory C. Donohoe et al.   ANALYTICAL CHEMISTRY

Conformational Analysis of Large and Highly Disulfide-Stabilized Proteins by Integrating Online Electrochemical Reduction into an Optimized H/D Exchange Mass Spectrometry Workflow

(2015) Esben Trabjerg et al.   ANALYTICAL CHEMISTRY

The Impact II, a Very High-Resolution Quadrupole Time-of-Flight Instrument (QTOF) for Deep Shotgun Proteomics

(2015) Scarlet Beck et al.   MOLECULAR & CELLULAR PROTEOMICS

Advances in high-resolution accurate mass spectrometry application to targeted proteomics

(2015) Antoine Lesur et al.   PROTEOMICS

Improving Qualitative and Quantitative Performance for MSE-based Label-free Proteomics

(2013) Nicholas J. Bond et al.   JOURNAL OF PROTEOME RESEARCH

Effects of Traveling Wave Ion Mobility Separation on Data Independent Acquisition in Proteomics Studies

(2013) Pavel V. Shliaha et al.   JOURNAL OF PROTEOME RESEARCH

Drift time-specific collision energies enable deep-coverage data-independent acquisition proteomics

(2013) Ute Distler et al.   NATURE METHODS

Protein hydrogen exchange at residue resolution by proteolytic fragmentation mass spectrometry analysis

(2013) Z.-Y. Kan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using ion purity scores for enhancing quantitative accuracy and precision in complex proteomics samples

(2012) Scott J. Geromanos et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Pepsin Immobilized on High-Strength Hybrid Particles for Continuous Flow Online Digestion at 10 000 psi

(2012) Joomi Ahn et al.   ANALYTICAL CHEMISTRY

Accessing the reproducibility and specificity of pepsin and other aspartic proteases

(2012) Joomi Ahn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Post-translational modifications induce significant yet not extreme changes to protein structure

(2012) Fuxiao Xin et al.   BIOINFORMATICS

HDX Workbench: Software for the Analysis of H/D Exchange MS Data

(2012) Bruce D. Pascal et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

ETD in a Traveling Wave Ion Guide at Tuned Z-Spray Ion Source Conditions Allows for Site-Specific Hydrogen/Deuterium Exchange Measurements

(2011) Kasper D. Rand et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Automated Hydrogen/Deuterium Exchange Electron Transfer Dissociation High Resolution Mass Spectrometry Measured at Single-Amide Resolution

(2011) Rachelle R. Landgraf et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Enhancements in travelling wave ion mobility resolution

(2011) Kevin Giles et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation

(2010) Zhongqi Zhang et al.   PROTEIN SCIENCE

Protein Hydrogen Exchange Measured at Single-Residue Resolution by Electron Transfer Dissociation Mass Spectrometry

(2009) Kasper D. Rand et al.   ANALYTICAL CHEMISTRY

Protein conformations can be probed in top-down HDX MS experiments utilizing electron transfer dissociation of protein ions without hydrogen scrambling

(2009) Rinat R. Abzalimov et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification forin situproteomic investigation of frozen and formalin-fixed paraffin-embedded adenocarcinoma tissue sections

(2009) Marie-Claude Djidja et al.   PROTEOMICS

The detection, correlation, and comparison of peptide precursor and product ions from data independent LC-MS with data dependant LC-MS/MS

(2009) Scott J. Geromanos et al.   PROTEOMICS

Epitope mapping by amide hydrogen/deuterium exchange coupled with immobilization of antibody, on-line proteolysis, liquid chromatography and mass spectrometry

(2009) Stephen J. Coales et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Dynamically Multiplexed Ion Mobility Time-of-Flight Mass Spectrometry

(2008) Mikhail E. Belov et al.   ANALYTICAL CHEMISTRY

Enhanced Ion Utilization Efficiency Using an Electrodynamic Ion Funnel Trap as an Injection Mechanism for Ion Mobility Spectrometry

(2008) Brian H. Clowers et al.   ANALYTICAL CHEMISTRY

Enhanced Digestion Efficiency, Peptide Ionization Efficiency, and Sequence Resolution for Protein Hydrogen/Deuterium Exchange Monitored by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

(2008) Hui-Min Zhang et al.   ANALYTICAL CHEMISTRY

High-Speed and High-Resolution UPLC Separation at Zero Degrees Celsius

(2008) Thomas E. Wales et al.   ANALYTICAL CHEMISTRY

Fast reversed-phase liquid chromatography to reduce back exchange and increase throughput in H/D exchange monitored by FT-ICR mass spectrometry

(2008) Hui-Min Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Ion mobility adds an additional dimension to mass spectrometric analysis of solution-phase hydrogen/deuterium exchange

(2008) Roxana E. Iacob et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY