The ubiquitin ligase SspH1 from Salmonella uses a modular and dynamic E3 domain to catalyze substrate ubiquitylation

The invasin D protein fromYersinia pseudotuberculosisselectively binds the Fab region of host antibodies and affects colonization of the intestine

(2018) Pooja Sadana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of catalysis, E2 recognition, and autoinhibition for the IpaH family of bacterial E3 ubiquitin ligases

(2017) Alexander F. A. Keszei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI

(2017) Lingmin Yuan et al.   Nature Communications

E2 enzymes: more than just middle men

(2016) Mikaela D Stewart et al.   CELL RESEARCH

Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms

(2016) Katja K Dove et al.   EMBO REPORTS

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

(2016) Haim Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

The structure of the Slrp–Trx1 complex sheds light on the autoinhibition mechanism of the type III secretion system effectors of the NEL family

(2014) Samira Zouhir et al.   BIOCHEMICAL JOURNAL

Convergent Evolution in the Assembly of Polyubiquitin Degradation Signals by theShigella flexneriIpaH9.8 Ligase

(2014) Daniel J. Edwards et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploitation of the host ubiquitin system by human bacterial pathogens

(2014) Hiroshi Ashida et al.   NATURE REVIEWS MICROBIOLOGY

Analysis of Overlapped and Noisy Hydrogen/Deuterium Exchange Mass Spectra

(2013) Miklos Guttman et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase

(2013) A. F. A. Keszei et al.   MOLECULAR AND CELLULAR BIOLOGY

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer

(2012) Hao Dou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions

(2012) D. Y.-w. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ubiquitin in Motion: Structural Studies of the Ubiquitin-Conjugating Enzyme∼Ubiquitin Conjugate

(2011) Jonathan N. Pruneda et al.   BIOCHEMISTRY

Conserved Structural Mechanisms for Autoinhibition in IpaH Ubiquitin Ligases

(2011) Yang-Chieh Chou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemistry and cell signaling taught by bacterial effectors

(2011) Jixin Cui et al.   TRENDS IN BIOCHEMICAL SCIENCES

Interactions of Bacterial Proteins with Host Eukaryotic Ubiquitin Pathways

(2011) Charlotte Averil Perrett et al.   Frontiers in Microbiology

Identification of an unconventional E3 binding surface on the UbcH5   Ub conjugate recognized by a pathogenic bacterial E3 ligase.

(2010) I. Levin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex

(2009) Hari B. Kamadurai et al.   MOLECULAR CELL

A family of Salmonella virulence factors functions as a distinct class of autoregulated E3 ubiquitin ligases

(2009) C. M. Quezada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a Shigella effector reveals a new class of ubiquitin ligases

(2008) Yongqun Zhu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases

(2008) Alexander U Singer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY