Design concepts of half-sandwich organoruthenium anticancer agents based on bidentate bioactive ligands
出版年份 2021 全文链接
标题
Design concepts of half-sandwich organoruthenium anticancer agents based on bidentate bioactive ligands
作者
关键词
Anticancer agents, Bidentate bioactive ligands, Bioorganometallics, Metallodrugs, Mode of action, Synergistic activity
出版物
COORDINATION CHEMISTRY REVIEWS
Volume 445, Issue -, Pages 213950
出版商
Elsevier BV
发表日期
2021-06-13
DOI
10.1016/j.ccr.2021.213950
参考文献
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- Hydroxydibenzoylmethane induces apoptosis through repressing ornithine decarboxylase in human promyelocytic leukemia HL-60 cells
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- A Potent Ruthenium(II) Antitumor Complex Bearing a Lipophilic Levonorgestrel Group
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- Antimony(V) and Bismuth(V) Complexes of Lapachol: Synthesis, Crystal Structure and Cytotoxic Activity
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- Physicochemical Studies and Anticancer Potency of Ruthenium η6-p-Cymene Complexes Containing Antibacterial Quinolones
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- “Rollover” cyclometalation – early history, recent developments, mechanistic insights and application aspects
- (2011) Burkhard Butschke et al. Chemical Science
- Functional Mimics of Glutathione Peroxidase: Bioinspired Synthetic Antioxidants
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- The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
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- Lidocaine: The Origin of a Modern Local Anesthetic
- (2010) Torsten Gordh et al. ANESTHESIOLOGY
- Synthesis and in vitro Anticancer Activities of some Selenadiazole Derivatives
- (2010) Daniel Plano et al. ARCHIV DER PHARMAZIE
- Influence of the Arene Ligand and the Leaving Group on the Anticancer Activity of (Thio)maltol Ruthenium(II)?(η6-Arene) Complexes
- (2010) Muhammad Hanif et al. AUSTRALIAN JOURNAL OF CHEMISTRY
- Antiviral agents 2. Synthesis of trimeric naphthoquinone analogues of conocurvone and their antiviral evaluation against HIV
- (2010) Ian T. Crosby et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Chelator Fragment Libraries for Targeting Metalloproteinases
- (2010) Arpita Agrawal et al. ChemMedChem
- Complex formation between Ru(η6-p-cym)(H2O)3]2+ and (O,O) donor ligands with biological relevance in aqueous solution
- (2010) Linda Bíró et al. DALTON TRANSACTIONS
- Synthesis and anticancer activity of chromone-based analogs of lavendustin A
- (2010) Dong Hyuk Nam et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- First Ruthenium Organometallic Complex of Antibacterial Agent Ofloxacin. Crystal Structure and Interactions with DNA
- (2010) Iztok Turel et al. INORGANIC CHEMISTRY
- Is the Reactivity of M(II)−Arene Complexes of 3-Hydroxy-2(1H)-pyridones to Biomolecules the Anticancer Activity Determining Parameter?
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- Structure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3β
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- Organometallic indolo[3,2-c]quinolines versus indolo[3,2-d]benzazepines: synthesis, structural and spectroscopic characterization, and biological efficacy
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- Identifying Chelators for Metalloprotein Inhibitors Using a Fragment-Based Approach
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- Anticancer activity of new organo-ruthenium, rhodium and iridium complexes containing the 2-(pyridine-2-yl)thiazole N,N-chelating ligand
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- Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials
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- Doxorubicin pathways
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- Plumbagin-induced apoptosis in lymphocytes is mediated through increased reactive oxygen species production, upregulation of Fas, and activation of the caspase cascade
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- Modulation of the Biological Properties of Aspirin by Formation of a Bioorganometallic Derivative
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- Synthesis of hydroxypyrone- and hydroxythiopyrone-based matrix metalloproteinase inhibitors: Developing a structure–activity relationship
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- Synthesis of novel thiourea, thiazolidinedione and thioparabanic acid derivatives of 4-aminoquinoline as potent antimalarials
- (2009) Naresh Sunduru et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Identification of Compounds Selectively Killing Multidrug-Resistant Cancer Cells
- (2009) D. Turk et al. CANCER RESEARCH
- Maltol-Derived Ruthenium-Cymene Complexes with Tumor Inhibiting Properties: The Impact of Ligand-Metal Bond Stability on Anticancer Activity In Vitro
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- Naphthalimides and Azonafides as Promising Anti-Cancer Agents
- (2009) Laurent Ingrassia et al. CURRENT MEDICINAL CHEMISTRY
- Noteworthy Secondary Metabolites Naphthoquinones – their Occurrence, Pharmacological Properties and Analysis
- (2009) Petr Babula et al. Current Pharmaceutical Analysis
- Inert ruthenium half-sandwich complexes with anticancer activity
- (2009) Eric Meggers et al. DALTON TRANSACTIONS
- A novel ruthenium(ii) arene based intercalator with potent anticancer activity
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- Biospeciation of various antidiabetic VIVO compounds in serum
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- Synthesis, molecular structure and evaluation of new organometallic ruthenium anticancer agents
- (2009) Kenneth D. Camm et al. DALTON TRANSACTIONS
- Ruthenium(II)–arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity
- (2009) Sanja Grgurić-Šipka et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis of Apoptosis-Inducing Iminophosphorane Organogold(III) Complexes and Study of Their Interactions with Biomolecular Targets
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- Organometallic ruthenium complexes with thiosemicarbazone ligands: Synthesis, structure and cytotoxicity of [(η6-p-cymene)Ru(NS)Cl]+ (NS=9-anthraldehyde thiosemicarbazones)
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- Inhibition of cancer cell growth by ruthenium(II) cyclopentadienyl derivative complexes with heteroaromatic ligands
- (2009) M. Helena Garcia et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Cytotoxicity of half sandwich ruthenium(II) complexes with strong hydrogen bond acceptor ligands and their mechanism of action
- (2009) Sangeeta Das et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Toward the Development of a Potent and Selective Organoruthenium Mammalian Sterile 20 Kinase Inhibitor
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- Transferring the Concept of Multinuclearity to Ruthenium Complexes for Improvement of Anticancer Activity
- (2009) Maria G. Mendoza-Ferri et al. JOURNAL OF MEDICINAL CHEMISTRY
- Amide Linkage Isomerism As an Activity Switch for Organometallic Osmium and Ruthenium Anticancer Complexes
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- Thioamide Hydroxypyrothiones Supersede Amide Hydroxypyrothiones in Potency against Anthrax Lethal Factor
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- Arene ruthenium β-diketonato triazolato derivatives: Synthesis and spectral studies (β-diketones: 1-phenyl-3-methyl-4-benzoyl pyrazol-5-one, acetylacetone derivatives)
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- Aspirin, salicylates, and cancer
- (2009) Peter C Elwood et al. LANCET
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- Ruthenium-based metallacrown complexes for the selective detection of lithium ions in water and in serum by fluorescence spectroscopy
- (2009) Sébastien Rochat et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- 4-Amino-1,8-naphthalimide-Based Tröger’s Bases As High Affinity DNA Targeting Fluorescent Supramolecular Scaffolds
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- (2008) Maria G. Mendoza-Ferri et al. APPLIED ORGANOMETALLIC CHEMISTRY
- Antiviral Agents. I. Synthesis and Antiviral Evaluation of Trimeric Naphthoquinone Analogues of Conocurvone
- (2008) Ian T. Crosby et al. AUSTRALIAN JOURNAL OF CHEMISTRY
- DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media
- (2008) Olga Nováková et al. BIOCHEMICAL PHARMACOLOGY
- Curcumin Inhibits the Proteasome Activity in Human Colon Cancer Cells In vitro and In vivo
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- Bioorganometallic chemistry—from teaching paradigms to medicinal applications
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- Medicinal Organometallic Chemistry: Designing Metal Arene Complexes as Anticancer Agents
- (2008) Anna F. A. Peacock et al. Chemistry-An Asian Journal
- Synthesis and biological evaluation of tetrahydroisoquinoline derivatives as potential multidrug resistance reversal agents in cancer
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- Recent developments on 3-hydroxy-4-pyridinones with respect to their clinical applications
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- Expanding the Size of Organometallic Nanostructures: A Hexanuclear (Cymene)Ru Cylinder with a Length of More Than 3 nm
- (2008) Céline Olivier et al. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
- Synthesis and biological activity evaluation of 1H-benzimidazoles via mammalian DNA topoisomerase I and cytostaticity assays
- (2008) Gunes Coban et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in L929 cells
- (2008) Faisal Thayyullathil et al. FREE RADICAL BIOLOGY AND MEDICINE
- Interactions of insulin–mimetic zinc(II) complexes with cell constituents: Glutathione and ATP
- (2008) Éva Anna Enyedy et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Evaluation of insulin-mimetic activities of vanadyl and zinc(II) complexes from the viewpoint of heterocyclic bidentate ligands
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- New tripodal hydroxypyridinone based chelating agents for Fe(III), Al(III) and Ga(III): Synthesis, physico-chemical properties and bioevaluation
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- Emerging Protein Targets for Anticancer Metallodrugs: Inhibition of Thioredoxin Reductase and Cathepsin B by Antitumor Ruthenium(II)−Arene Compounds
- (2008) Angela Casini et al. JOURNAL OF MEDICINAL CHEMISTRY
- A Non-Cross-Linking Platinum−Acridine Agent with Potent Activity in Non-Small-Cell Lung Cancer
- (2008) Zhidong Ma et al. JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer
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- Tuning the anticancer activity of maltol-derived ruthenium complexes by derivatization of the 3-hydroxy-4-pyrone moiety
- (2008) Wolfgang Kandioller et al. JOURNAL OF ORGANOMETALLIC CHEMISTRY
- Organometallic complexes that interconvert between trimeric and monomeric structures as a function of pH and their effect on human cancer and fibroblast cells
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- Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes
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- Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma
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- Syntheses and in vitro evaluation of arylsulfone-based MMP inhibitors with heterocycle-derived zinc-binding groups (ZBGs)
- (2007) Yue-Mei Zhang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Antitumour metal compounds: more than theme and variations
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