Targeting the DNA-topoisomerase complex in a double-strike approach with a topoisomerase inhibiting moiety and covalent DNA binder

Synthesis, Characterization, and Cytotoxic Activity of Novel Potentially pH-Sensitive Nonclassical Platinum(II) Complexes Featuring 1,3-Dihydroxyacetone Oxime Ligands

(2011) Yulia Yu. Scaffidi-Domianello et al.   INORGANIC CHEMISTRY

Half-sandwich ruthenium–arene complexes with thiosemicarbazones: Synthesis and biological evaluation of [(η6-p-cymene)Ru(piperonal thiosemicarbazones)Cl]Cl complexes

(2011) Floyd Beckford et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Role of Metalation in the Topoisomerase IIα Inhibition and Antiproliferation Activity of a Series of α-Heterocyclic-N4-Substituted Thiosemicarbazones and Their Cu(II) Complexes

(2011) Brian M. Zeglis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, single-crystal and solution structure analysis and in vitro cytotoxic activity of two novel complexes of ruthenium(ii) with in situ formed flavanone-based ligands.

(2010) Justyn Ochocki et al.   DALTON TRANSACTIONS

Organometallic ruthenium-based antitumor compounds with novel modes of action

(2010) Wee Han Ang et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Modulation of the Biological Properties of Aspirin by Formation of a Bioorganometallic Derivative

(2009) Ingo Ott et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rational Design of an Organometallic Glutathione Transferase Inhibitor

(2009) Wee Han Ang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ferrocenyl Quinone Methides as Strong Antiproliferative Agents: Formation by Metabolic and Chemical Oxidation of Ferrocenyl Phenols

(2009) Didier Hamels et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biological activity of metal ions complexes of chromones, coumarins and flavones

(2009) Magdalena Grazul et al.   COORDINATION CHEMISTRY REVIEWS

Syntheses, characterization and antitumor activities of transition metal complexes with isoflavone

(2009) Xiang Chen et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

From Pyrone to Thiopyrone Ligands−Rendering Maltol-Derived Ruthenium(II)−Arene Complexes That Are Anticancer Active in Vitro

(2009) Wolfgang Kandioller et al.   ORGANOMETALLICS

Influence of the Arene Ligand, the Number and Type of Metal Centers, and the Leaving Group on thein VitroAntitumor Activity of Polynuclear Organometallic Compounds

(2009) Maria G. Mendoza-Ferri et al.   ORGANOMETALLICS

DNA Binding, Photocleavage, and Topoisomerase Inhibition of Functionalized Ruthenium(II)-Polypyridine Complexes

(2008) Feng Gao et al.   CHEMISTRY & BIODIVERSITY

Understanding the Cardioprotective Effects of Flavonols: Discovery of Relaxant Flavonols without Antioxidant Activity

(2008) Cheng Xue Qin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Tuning the anticancer activity of maltol-derived ruthenium complexes by derivatization of the 3-hydroxy-4-pyrone moiety

(2008) Wolfgang Kandioller et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Influence of the Spacer Length on thein VitroAnticancer Activity of Dinuclear Ruthenium−Arene Compounds

(2008) Maria-Grazia Mendoza-Ferri et al.   ORGANOMETALLICS