Oxicams, a class of nonsteroidal anti-inflammatory drugs and beyond

Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network

(2014) Shu Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis, spectroscopic and DFT structural characterization of two novel ruthenium(III) oxicam complexes. In vivo evaluation of anti-inflammatory and gastric damaging activities

(2014) Gabriella Tamasi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Crystal structure of microsomal prostaglandin E2 synthase provides insight into diversity in the MAPEG superfamily

(2013) T. Sjogren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spectroscopic studies of the binding of Cu(II) complexes of oxicam NSAIDs to alternating G-C and homopolymeric G-C sequences

(2013) Sreeja Chakraborty et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Meloxicam ameliorates motor dysfunction and dopaminergic neurodegeneration by maintaining Akt-signaling in a mouse Parkinson's disease model

(2012) Yoshikazu Tasaki et al.   NEUROSCIENCE LETTERS

Oxicam structure in non-steroidal anti-inflammatory drugs is essential to exhibit Akt-mediated neuroprotection against 1-methyl-4-phenyl pyridinium-induced cytotoxicity

(2011) Yoshikazu Tasaki et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Structural Basis of Endocannabinoid Oxygenation by Cyclooxygenase-2

(2011) Alex J. Vecchio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor

(2010) Gabriel Mbalaviele et al.   BIOCHEMICAL PHARMACOLOGY

The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life

(2010) Jane L. Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Selective inducible microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors derived from an oxicam template

(2010) Jane Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

X-Ray Structural Characterization of the Bis-Guanine Derivative of a Cisplatin Analogue Having Just One Proton on Each Coordinated Nitrogen and a Head-to-Head Conformation: [Pt{(±)-N,N′-Dimethyl-2,3-diaminobutane}(9-ethyl-guanine)2]dinitrate

(2010) Francesco P. Intini et al.   INORGANIC CHEMISTRY

Structural Basis of Fatty Acid Substrate Binding to Cyclooxygenase-2

(2010) Alex J. Vecchio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Basis for Cyclooxygenase Inhibition by the Non-steroidal Anti-inflammatory Drug Naproxen

(2010) Kelsey C. Duggan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New platinum–oxicam complexes as anti-cancer drugs. Synthesis, characterization, release studies from smart hydrogels, evaluation of reactivity with selected proteins and cytotoxic activity in vitro

(2010) Gabriella Tamasi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

First-Principles Prediction of the pKas of Anti-inflammatory Oxicams

(2010) Junming Ho et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Complex formation of the anti-inflammatory drugs tenoxicam and piroxicam with Fe(III) in methanol and acetone

(2008) Rosario Moya-Hernández et al.   JOURNAL OF COORDINATION CHEMISTRY

Structural basis for induced formation of the inflammatory mediator prostaglandin E2

(2008) C. Jegerschold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA