New series of benzothiazole and pyrimido[2,1-b]benzothiazole derivatives: synthesis, antitumor activity, EGFR tyrosine kinase inhibitory activity and molecular modeling studies

Tyrosine Kinase Inhibitors: Views of Selectivity, Sensitivity, and Clinical Performance

(2012) Alexander Levitzki   Annual Review of Pharmacology and Toxicology

Benzothiazoles: Search for anticancer agents

(2012) Malleshappa N. Noolvi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation of antimicrobial activity of 4H-pyrimido[2,1-b]benzothiazole, pyrazole and benzylidene derivatives of curcumin

(2012) Pramod K. Sahu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Computation of relative binding free energy for an inhibitor and its analogs binding with Erk kinase using thermodynamic integration MD simulation

(2012) Kuan-Wei Wu et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Synthesis and Biological Evaluation of Novel Benzothiazole-2-thiol Derivatives as Potential Anticancer Agents

(2012) Xuan-Hong Shi et al.   MOLECULES

Synthesis, characterization of some benzazoles bearing pyridine moiety: Search for novel anticancer agents

(2011) Heba S.A. Elzahabi   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

ReverseScreen3D: A Structure-Based Ligand Matching Method To Identify Protein Targets

(2011) Sarah L. Kinnings et al.   Journal of Chemical Information and Modeling

The molecular mechanism studies of chirality effect of PHA-739358 on Aurora kinase A by molecular dynamics simulation and free energy calculations

(2011) Yuanhua Cheng et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Synthesis of benzothiazole derivatives having acetamido and carbothioamido pharmacophore as anticonvulsant agents

(2011) Mohd. Amir et al.   MEDICINAL CHEMISTRY RESEARCH

SwissDock, a protein-small molecule docking web service based on EADock DSS

(2011) A. Grosdidier et al.   NUCLEIC ACIDS RESEARCH

Synthesis, and biological evaluation of 2-(4-aminophenyl)benzothiazole derivatives as photosensitizing agents

(2010) Wan-Ping Hu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Lapatinib, a Dual EGFR and HER2 Kinase Inhibitor, Selectively Inhibits HER2-Amplified Human Gastric Cancer Cells and is Synergistic with Trastuzumab In vitro and In vivo

(2010) Z. A. Wainberg et al.   CLINICAL CANCER RESEARCH

Erlotinib in Advanced Non-small Cell Lung Cancer: Efficacy and Safety Findings of the Global Phase IV Tarceva Lung Cancer Survival Treatment Study

(2010) Martin Reck et al.   Journal of Thoracic Oncology

Gatekeeper Mutations Mediate Resistance to BRAF-Targeted Therapies

(2010) S. Whittaker et al.   Science Translational Medicine

Synthesis, antioxidant properties and radioprotective effects of new benzothiazoles and thiadiazoles

(2009) Damien Cressier et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of thiazolidinone derivatives as potential EGFR and HER-2 kinase inhibitors

(2009) Peng-Cheng Lv et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Receptor Tryosine Kinase Inhibitors as Potent Weapons in War Against Cancers

(2009) P. Sharma et al.   CURRENT PHARMACEUTICAL DESIGN

Synthesis, characterization and biological evaluation of some thiourea derivatives bearing benzothiazole moiety as potential antimicrobial and anticancer agents

(2009) Sohail Saeed et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of new spiroindolinones incorporating a benzothiazole moiety as antioxidant agents

(2009) Nilgün Karalı et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Evaluation of new thiadiazoles and benzothiazoles as potential radioprotectors: Free radical scavenging activity in vitro and theoretical studies (QSAR, DFT)

(2009) Caroline Prouillac et al.   FREE RADICAL BIOLOGY AND MEDICINE

Through the “Gatekeeper Door”: Exploiting the Active Kinase Conformation

(2009) Fabio Zuccotto et al.   JOURNAL OF MEDICINAL CHEMISTRY

The challenge of selecting protein kinase assays for lead discovery optimization

(2008) Haiching Ma et al.   Expert Opinion on Drug Discovery