Novel metal(ii) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents

Designing organometallic compounds for catalysis and therapy

(2012) Anna Louisa Noffke et al.   CHEMICAL COMMUNICATIONS

Capillary electrophoretic methods in the development of metal-based therapeutics and diagnostics: New methodology and applications

(2012) Anna K. Bytzek et al.   ELECTROPHORESIS

Beyond Size, Ionization State, and Lipophilicity: Influence of Molecular Topology on Absorption, Distribution, Metabolism, Excretion, and Toxicity for Druglike Compounds

(2012) Yidong Yang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Unsymmetric Mono- and Dinuclear Platinum(IV) Complexes Featuring an Ethylene Glycol Moiety: Synthesis, Characterization, and Biological Activity

(2012) Verena Pichler et al.   JOURNAL OF MEDICINAL CHEMISTRY

Combination of metallomics and proteomics to study the effects of the metallodrug RAPTA-T on human cancer cells

(2012) Dirk A. Wolters et al.   Metallomics

Quantifying the chemical beauty of drugs

(2012) G. Richard Bickerton et al.   Nature Chemistry

Rethinking the term “pi-stacking”

(2012) Chelsea R. Martinez et al.   Chemical Science

A Ruthenium Antimetastasis Agent Forms Specific Histone Protein Adducts in the Nucleosome Core

(2011) Bin Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Bioanalytical and Biophysical Techniques for the Elucidation of the Mode of Action of Metal-Based Drugs

(2011) Michael Groessl et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Structure–activity relationships for organometallic osmium arene phenylazopyridine complexes with potent anticancer activity

(2011) Ying Fu et al.   DALTON TRANSACTIONS

Biomolecule binding vs. anticancer activity: Reactions of Ru(arene)[(thio)pyr-(id)one] compounds with amino acids and proteins

(2011) Samuel M. Meier et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Organometallic Ruthenium(II) Arene Compounds with Antiangiogenic Activity

(2011) Patrycja Nowak-Sliwinska et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

(2011) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Organometallic Cages as Vehicles for Intracellular Release of Photosensitizers

(2011) Frédéric Schmitt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation

(2011) Bin Wu et al.   NUCLEIC ACIDS RESEARCH

Anti-colorectal cancer activity of an organometallic osmium arene azopyridine complex

(2011) Steve D. Shnyder et al.   MedChemComm

Identifying drug metallation sites on peptides using electron transfer dissociation (ETD), collision induced dissociation (CID) and ion mobility-mass spectrometry (IM-MS)

(2010) Jonathan P. Williams et al.   CHEMICAL COMMUNICATIONS

Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes

(2010) Michael R. Reithofer et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Organometallic Osmium Arene Complexes with Potent Cancer Cell Cytotoxicity

(2010) Ying Fu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rational Design of an Organometallic Glutathione Transferase Inhibitor

(2009) Wee Han Ang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Maltol-Derived Ruthenium-Cymene Complexes with Tumor Inhibiting Properties: The Impact of Ligand-Metal Bond Stability on Anticancer Activity In Vitro

(2009) Wolfgang Kandioller et al.   CHEMISTRY-A EUROPEAN JOURNAL

In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model

(2009) A. Bergamo et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Transferring the Concept of Multinuclearity to Ruthenium Complexes for Improvement of Anticancer Activity

(2009) Maria G. Mendoza-Ferri et al.   JOURNAL OF MEDICINAL CHEMISTRY

Amide Linkage Isomerism As an Activity Switch for Organometallic Osmium and Ruthenium Anticancer Complexes

(2009) Sabine H. van Rijt et al.   JOURNAL OF MEDICINAL CHEMISTRY

From Pyrone to Thiopyrone Ligands−Rendering Maltol-Derived Ruthenium(II)−Arene Complexes That Are Anticancer Active in Vitro

(2009) Wolfgang Kandioller et al.   ORGANOMETALLICS

Bioorganometallic chemistry—from teaching paradigms to medicinal applications

(2008) Christian G. Hartinger et al.   CHEMICAL SOCIETY REVIEWS

Current Status and Future Prospects for Satraplatin, an Oral Platinum Analogue

(2008) H. Choy et al.   CLINICAL CANCER RESEARCH

The ruthenium(II)–arene compound RAPTA-C induces apoptosis in EAC cells through mitochondrial and p53–JNK pathways

(2008) Soumya Chatterjee et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY