Article
Chemistry, Multidisciplinary
Thomas E. Reason, Benjamin Goka, Jeanette A. Krause, Abelline K. Fionah, Elsayed M. Zahran, Sundeep Rayat
Summary: The efficient method reported involves C-N coupling of aryl tetrazolones with aryl boronic acids using Cu2O nanoparticles under oxygen atmosphere. The reaction produces 1,4-diaryl tetrazolones with diverse substituents in moderate to good yields. In the crystal lattice, the molecules exhibit specific stacking and through-space interactions, resulting in identical patterns for structurally similar compounds.
Article
Agronomy
Xin Wu, Mengwei Bu, Zili Yang, Hongrui Ping, Chunlin Song, Jiang Duan, Aidong Zhang
Summary: This study designed a series of fosmidomycin analogs with thiourea linkers, and evaluated their biological activities against IspC enzyme and model plants. The results showed that some compounds had moderate inhibitory effects on the enzyme and plant growth. Particularly, compound 10g exhibited the best plant inhibition activities and represented a potential lead structure for new herbicide discovery.
PEST MANAGEMENT SCIENCE
(2023)
Article
Engineering, Biomedical
Ziying Zhang, Liang Ma, Hui Yuan, Ziman Chen, Yongqin Lv
Summary: A new recognition method for rapid detection of B-type natriuretic peptide (BNP) using molecularly imprinted nanoparticles (nanoMIP) encapsulated with carbon dots is explored. The nanoMIP exhibits high affinity and selectivity toward BNP with a detection limit of 0.208 pg mL(-1). Real serum samples from 160 individuals are analyzed, and the method shows high accuracy and reliability compared to the routine electrochemiluminescence detection method.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Crystallography
Dmitriy I. Shlimas, Artem L. Kozlovskiy, Maxim V. Zdorovets
Summary: This paper introduces a method for obtaining stable Li2TiO3 ceramics through solid-phase synthesis and high-temperature sintering, and studies the temperature dependence of phase transformations and changes in structural, optical, and ferroelectric characteristics using X-ray diffraction methods.
Article
Chemistry, Organic
Sohan Lal, Richard J. Staples, Jean'ne M. Shreeve
Summary: A straightforward synthetic strategy was reported for newly designed nitrogen-rich planar explosives and solid propellants. These materials exhibit high densities (1.69-1.95 g cm(-3)), high positive enthalpies of formation (approaching 1149.21 kJ mol(-1)), promising energetic properties (P = 26.36-33.78 GPa, D = 8258-9518 m s(-1)), acceptable thermal stabilities (T (d) = 132-277°C), good sensitivities (IS = 4-40 J, FS = 60-360 N), and excellent propulsive performance (Isp = 176.80-253.06 s).
Review
Chemistry, Multidisciplinary
Vladimir V. Chernyshov, Irina I. Popadyuk, Olga Yarovaya, Nariman F. Salakhutdinov
Summary: The directed transformation of available natural compounds is a promising research area in organic and medicinal chemistry for finding effective drug substances. This review aims to summarize the literature data on the preparation and properties of nitrogen-containing heterocyclic compounds synthesized from monoterpenes/monoterpenoids and their nearest derivatives from 2000 to 2021.
TOPICS IN CURRENT CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Kai Jin, Miao Lv, Tengfei Wang, Zhengjun Gong
Summary: In this study, the fuel properties of hydrochar pellets derived from various N-containing biowastes were investigated through hydrothermal carbonization and pelletization. The introduction of N significantly enhanced the compressive strength of hydrochar pellets. Chlorella-derived hydrochar pellets exhibited the highest tensile strength. Protein/P model hydrochar had a higher water resistance index, while glycine/P model hydrochar was more hydrophilic. The N-containing biowaste had a significant effect on the fuel properties of hydrochar pellets, offering potential for value-added utilization as solid biofuel.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2023)
Article
Biochemistry & Molecular Biology
Valeria Romanucci, Maddalena Giordano, Rita Pagano, Stefania Zimbone, Maria Laura Giuffrida, Danilo Milardi, Armando Zarrelli, Giovanni Di Fabio
Summary: This study presents an efficient solid-phase approach for obtaining new prodrugs of silybins conjugated with uridine and adenosine as pro-moieties, with improved solubility and potential for controlled drug release. Uridine conjugates were found to be quickly cleaved by RNase A, releasing the active drug, without exhibiting toxicity in neuroblastoma cells. These results encourage further exploration of uridine-silybin prodrugs for potential therapeutic applications.
BIOORGANIC & MEDICINAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Perrine M. R. Wingering, Silvia Hohnstein, Felix Kraemer, Melina E. A. Dilanas, Cristina Ruiz-Martinez, Ignacio Fernandez, Frank Breher
Summary: The synthesis and characterization of rare earth element complexes (Ln=Y, La, Sm, Lu, Ce) of several podant & kappa;N-6-coordinating ligands were conducted. The structural properties of the complexes were studied using X-ray diffraction and advanced NMR methods. To evaluate the donor capabilities of the ligands, cyclic voltammetry, absorption experiments, and Y-89 NMR chemical shift analysis were performed. Quantum chemical calculations were also used to support the experimental findings. Furthermore, coordination competition studies were carried out using H-1 and P-31 NMR spectroscopy to investigate the correlation with donor properties and selectivity.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Polymer Science
Zhijian Zhang, Kai Yang, Jianying Li, Zhenghong Jing, Yawei Qin, Jin-Yong Dong
Summary: The use of omega-alkenylmethyldichlorosilane as a long-chain-branching agent in the fully implemented impact copolymerization of propylene has shown significant improvements in IPCs. The introduction of LCB structures has led to advancements in melt properties, phase morphology, melt crystallization, and mechanical properties of the copolymer, resulting in enhanced stiffness and toughness.
Review
Chemistry, Multidisciplinary
Tim Seedorf, Andreas Kirschning, Danny Solga
Summary: The term privileged structure refers to a single molecular substructure or scaffold that can serve as a starting point for high-affinity ligands for more than one receptor type. In this study, aromatic oligoamides, with well-defined scaffolds capable of specifically binding to biomacromolecules, have been identified as a group of privileged substructures. These oligoamides, including cystobactamids, albicidin, distamycin A, netropsin, have been shown to inhibit protein-protein and nucleic acid-protein interactions. This report is the first to consolidate scattered knowledge about aromatic oligoamides in connection with biomedical applications.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Materials Science, Multidisciplinary
D. Luo, P. Wang, Q. Zheng, R. Han, C. Shi, L. Wang, Y. Hong, Y. Liu, Y. Sha
Summary: The research utilized MNP/SiO2 as a solid phase in Fmoc chemistry for solid-phase peptide synthesis, demonstrating its excellent potential for applications.
MATERIALS TODAY ADVANCES
(2021)
Article
Chemistry, Inorganic & Nuclear
Shingo Masahara, Hiromichi Yokoyama, Yuji Suzaki, Tomohito Ide
Summary: In this study, the heterogenous reaction between copper(I) halide and pyridine derivative ligand produced luminescent copper(I) complexes. The progress of the reaction was monitored using PXRD and TG measurements, and the structure was elucidated by comparing it to single crystal X-ray analysis. The reaction proceeded quantitatively, regardless of the type of copper(I) halide used, when specific solvents and ligands were employed.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Multidisciplinary
Thomas Delouche, Ghizlene Taifour, Marie Cordier, Thierry Roisnel, Denis Tondelier, Payal Manzhi, Bernard Geffroy, Boris Le Guennic, Denis Jacquemin, Muriel Hissler, Pierre-Antoine Bouit
Summary: A straightforward synthesis of Si-containing PAHs is reported, with investigation into the impact of pi-extension and exocyclic modifications on optical and redox properties using a joint experimental/theoretical approach. Preliminary opto-electronic results indicate that these heteroatom-containing PAHs may serve as promising building blocks for organic electronics, as demonstrated by the preparation of electroluminescent devices utilizing the solid-state luminescence of these derivatives.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Inorganic & Nuclear
Liuzhong Yuan, Yujia Liu, Wenting Sun, Kaiqi Ye, Chuandong Dou, Yue Wang
Summary: Incorporation of heteroatoms into polyarenes has been proven to be an effective method to modify their structures and properties. In this study, P=O-containing dibenzopentaarene isomers (5a and 5b) were designed and synthesized, and their structures and properties were investigated alongside dibenzopentaarenes containing Si and B heterocycles (3 and 4). The incorporation of heterocycles greatly influenced the molecular and packing structures, as well as the electronic structures and properties of the polyarenes.
DALTON TRANSACTIONS
(2022)
