Lipophilicity-antiproliferative activity relationship study leads to the preparation of a ruthenium(II) arene complex with considerable in vitro cytotoxicity against cancer cells and a lower in vivo toxicity in zebrafish embryos than clinically approved cis -platin

标题
Lipophilicity-antiproliferative activity relationship study leads to the preparation of a ruthenium(II) arene complex with considerable in vitro cytotoxicity against cancer cells and a lower in vivo toxicity in zebrafish embryos than clinically approved cis -platin
作者
关键词
Ruthenium complexes, Antiproliferative activity, Lipophilicity, Cancer, In vivo, toxicity, Zebrafish
出版物
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 132, Issue -, Pages 282-293
出版商
Elsevier BV
发表日期
2017-03-19
DOI
10.1016/j.ejmech.2017.03.029

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