Physiological roles of hydrogen sulfide in mammalian cells, tissues and organs

Mitochondrion-targeting near-infrared fluorescent probe for detecting intracellular nanomolar level hydrogen sulfide with high recognition rate

(2021) Kaiquan Zhang et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Comparative transcriptome analysis uncovers roles of hydrogen sulfide for alleviating cadmium toxicity in Tetrahymena thermophila

(2021) Hongrui Lv et al.   BMC GENOMICS

Nitric oxide and hydrogen sulfide: Sibling rivalry in the family of epigenetic regulators

(2021) Hannah Petraitis Kuschman et al.   FREE RADICAL BIOLOGY AND MEDICINE

H2S As A Therapeutic Adjuvant Against COVID-19

(2021) Thomas Datzmann et al.   SHOCK

Plasma hydrogen sulfide: A biomarker of Alzheimer's disease and related dementias

(2021) Elizabeth Disbrow et al.   Alzheimers & Dementia

Activation of Endogenous H2S Biosynthesis or Supplementation with Exogenous H2S Enhances Adipose Tissue Adipogenesis and Preserves Adipocyte Physiology in Humans

(2021) Ferran Comas et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy Plays a Protective Role in Sodium Hydrosulfide-Induced Acute Lung Injury by Attenuating Oxidative Stress and Inflammation in Rats

(2021) Shuai Zhang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Hydrogen sulfide is synthesized endogenously in both retinal artery and retina mostly via CSE

(2021) Selçuk Takır et al.   EXPERIMENTAL EYE RESEARCH

The Potential of Hydrogen Sulfide Donors in Treating Cardiovascular Diseases

(2021) Yi-Zhen Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hydrogen sulphide reduces hyperhomocysteinaemia‐induced endothelial ER stress by sulfhydrating protein disulphide isomerase to attenuate atherosclerosis

(2021) Shan Jiang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Meta-analysis of gene expression patterns in Down syndrome highlights significant alterations in mitochondrial and bioenergetic pathways

(2021) Laszlo Pecze et al.   MITOCHONDRION

SIRT1 Mediates H2S-Ameliorated Diabetes-Associated Cognitive Dysfunction in Rats: Possible Involvement of Inhibiting Hippocampal Endoplasmic Reticulum Stress and Synaptic Dysfunction

(2021) Juan He et al.   NEUROCHEMICAL RESEARCH

Hydrogen Sulfide Restored the Diurnal Variation in Cardiac Function of Aging Mice

(2021) Huaxing Zhang et al.   Oxidative Medicine and Cellular Longevity

Pharmacological induction of mesenchymal-epithelial transition via inhibition of H2S biosynthesis and consequent suppression of ACLY activity in colon cancer cells

(2021) Kelly Ascenção et al.   PHARMACOLOGICAL RESEARCH

Human METTL7B is an alkyl thiol methyltransferase that metabolizes hydrogen sulfide and captopril

(2021) Benjamin J. Maldonato et al.   Scientific Reports

The Role of the Transsulfuration Pathway in Non-Alcoholic Fatty Liver Disease

(2021) Mikkel Parsberg Werge et al.   Journal of Clinical Medicine

Selenium-Binding Protein 1 (SELENBP1) Supports Hydrogen Sulfide Biosynthesis and Adipogenesis

(2021) Elisa B. Randi et al.   Antioxidants

Harnessing the Benefits of Endogenous Hydrogen Sulfide to Reduce Cardiovascular Disease

(2021) Kevin M. Casin et al.   Antioxidants

Fighting Oxidative Stress with Sulfur: Hydrogen Sulfide in the Renal and Cardiovascular Systems

(2021) Joshua J. Scammahorn et al.   Antioxidants

Investigating Different Forms of Hydrogen Sulfide in Cerebrospinal Fluid of Various Neurological Disorders

(2021) Viviana Greco et al.   Metabolites

An evolutionary perspective on the interplays between hydrogen sulfide and oxygen in cellular functions

(2021) Jiechun Zhu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Effects of gut microbiota on atherosclerosis through hydrogen sulfide

(2021) Dan-Dan Gui et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Novel Hydrogen Sulfide (H2S)-Releasing BW-HS-101 and Its Non-H2S Releasing Derivative in Modulation of Microscopic and Molecular Parameters of Gastric Mucosal Barrier

(2021) Dominik Bakalarz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Novel Aryl-Substituted Pyrimidones as Inhibitors of 3-Mercaptopyruvate Sulfurtransferase with Antiproliferative Efficacy in Colon Cancer

(2021) Marina Bantzi et al.   JOURNAL OF MEDICINAL CHEMISTRY

GYY4137 alleviates sepsis-induced acute lung injury in mice by inhibiting the PDGFRβ/Akt/NF-κB/NLRP3 pathway

(2021) Jianhua Li et al.   LIFE SCIENCES

Therapeutic potential of endogenous hydrogen sulfide inhibition in breast cancer (Review)

(2021) Ming Li et al.   ONCOLOGY REPORTS

Hydrogen sulfide: An emerging signaling molecule regulating drought stress response in plants

(2021) Meenakshi Thakur et al.   PHYSIOLOGIA PLANTARUM

Endogenous hydrogen sulfide regulates xCT stability through persulfidation of OTUB1 at cysteine 91 in colon cancer cells

(2021) Shanwen Chen et al.   NEOPLASIA

Hypertension and Aging Affect Liver Sulfur Metabolism in Rats

(2021) Dominika Szlęzak et al.   Cells

The Impact of H2S on Obesity-Associated Metabolic Disturbances

(2021) Ferran Comas et al.   Antioxidants

Hydrogen Sulfide as a Potential Therapy for Heart Failure—Past, Present, and Future

(2021) Kyle B. LaPenna et al.   Antioxidants

Accurate Fluorescence Diagnosis of Cancer Based on Sequential Detection of Hydrogen Sulfide and pH

(2021) Zun-Pan She et al.   ANALYTICAL CHEMISTRY

Hydrogen Sulfide Metabolite, Sodium Thiosulfate: Clinical Applications and Underlying Molecular Mechanisms

(2021) Max Y. Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut microbiota-derived metabolites in CRC progression and causation

(2021) Nishu Dalal et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Polysulfide inhibits hypoxia-elicited hypoxia-inducible factor activation in a mitochondria-dependent manner

(2021) Takeo Uba et al.   MITOCHONDRION

Inhibitors of bacterial H2S biogenesis targeting antibiotic resistance and tolerance

(2021) Konstantin Shatalin et al.   SCIENCE

Endogenous Hydrogen Sulfide Is an Important Factor in Maintaining Arterial Oxygen Saturation

(2021) Yan Huang et al.   Frontiers in Pharmacology

Duchenne's muscular dystrophy involves a defective transsulfuration pathway activity

(2021) E. Panza et al.   Redox Biology

Decreased availability of nitric oxide and hydrogen sulfide is a hallmark of COVID-19

(2021) Paari Dominic et al.   Redox Biology

Cysteine Boosts Fitness Under Hypoxia-Mimicked Conditions in Ovarian Cancer by Metabolic Reprogramming

(2021) Sofia C. Nunes et al.   Frontiers in Cell and Developmental Biology

Efficacy of Novel Aminooxyacetic Acid Prodrugs in Colon Cancer Models: Towards Clinical Translation of the Cystathionine β-Synthase Inhibition Concept

(2021) Mark R. Hellmich et al.   Biomolecules

Hydrogen Sulfide Contributes to Uterine Quiescence Through Inhibition of NLRP3 Inflammasome Activation by Suppressing the TLR4/NF-κB Signalling Pathway

(2021) Zixi Chen et al.   Journal of Inflammation Research

H2S as a Bridge Linking Inflammation, Oxidative Stress and Endothelial Biology: A Possible Defense in the Fight against SARS-CoV-2 Infection?

(2021) Francesca Gorini et al.   Biomedicines

Hydrogen Sulfide Inhibits TMPRSS2 in Human Airway Epithelial Cells: Implications for SARS-CoV-2 Infection

(2021) Giulia Pozzi et al.   Biomedicines

Electrical Power Generation Using Dynamic Piezoelectric Shear Deformation Under Friction

(2021) Peng Wang et al.   ACTA MECHANICA SOLIDA SINICA

Engineering macromolecular nanocarriers for local delivery of gaseous signaling molecules

(2021) Jinming Hu et al.   ADVANCED DRUG DELIVERY REVIEWS

Role of Hydrogen Sulfide, Substance P and Adhesion Molecules in Acute Pancreatitis

(2021) Ayush Kumar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Reprogrammed transsulfuration promotes basal-like breast tumor progression via realigning cellular cysteine persulfidation

(2021) Katalin Erdélyi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The hepatic compensatory response to elevated systemic sulfide promotes diabetes

(2021) Roderick N. Carter et al.   Cell Reports

The Capacity to Produce Hydrogen Sulfide (H2S) via Cysteine Degradation Is Ubiquitous in the Human Gut Microbiome

(2021) Domenick J. Braccia et al.   Frontiers in Microbiology

A hydrogen sulfide-releasing alginate dressing for effective wound healing

(2020) Xia Zhao et al.   Acta Biomaterialia

Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase

(2020) Maria Peleli et al.   BIOCHEMICAL PHARMACOLOGY

Hydrogen Sulfide Switch Phenomenon Regulating Autophagy in Cardiovascular Diseases

(2020) Wen Luo et al.   CARDIOVASCULAR DRUGS AND THERAPY

Role of Hydrogen Sulfide in Chronic Diseases

(2020) Na Yang et al.   DNA AND CELL BIOLOGY

Assessment of the effect of sodium hydrogen sulfide (hydrogen sulfide donor) on cisplatin-induced testicular toxicity in rats

(2020) Nastaran Azarbarz et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Hydrogen sulfide protects against particle‐induced inflammatory response and osteolysis via SIRT1 pathway in prosthesis loosening

(2020) Lei Liu et al.   FASEB JOURNAL

The re‐emerging pathophysiological role of the cystathionine‐β‐synthase ‐ hydrogen sulfide system in Down syndrome

(2020) Csaba Szabo   FEBS Journal

Endogenous hydrogen sulfide alleviates methotrexate‐induced cognitive impairment by attenuating endoplasmic reticulum stress‐induced apoptosis via CHOP and caspase‐12

(2020) Siyuan Lv et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Exogenous Hydrogen Sulfide Regulates Mycoplasma pneumoniae Lipid-Associated Membrane Proteins to Induce Expression of Heme Oxygenase-1 and Proinflammatory Cytokines

(2020) Xinnian Hu et al.   INFLAMMATION

Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disulfiduria

(2020) Noriyuki Akahoshi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hydrogen Sulfide as Potential Regulatory Gasotransmitter in Arthritic Diseases

(2020) Flavia Sunzini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transcriptome analysis reveals delaying of the ripening and cell‐wall degradation of kiwifruit by hydrogen sulfide

(2020) Xiaocui Lin et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Caveolae in CNS arterioles mediate neurovascular coupling

(2020) Brian W. Chow et al.   NATURE

Energy-stress-mediated AMPK activation inhibits ferroptosis

(2020) Hyemin Lee et al.   NATURE CELL BIOLOGY

Maternal disease and gasotransmitters

(2020) Aishwarya Rengarajan et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Gut microbiota and neuroinflammation in pathogenesis of hypertension: A potential role for hydrogen sulfide

(2020) Basak Donertas Ayaz et al.   PHARMACOLOGICAL RESEARCH

Sulfhydration of AKT triggers Tau-phosphorylation by activating glycogen synthase kinase 3β in Alzheimer’s disease

(2020) Tanusree Sen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen sulfide dysregulates the immune response by suppressing central carbon metabolism to promote tuberculosis

(2020) Md. Aejazur Rahman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Urinary Sulfate Excretion and Risk of Late Graft Failure in Renal Transplant Recipients

(2020) M. Yusof Said et al.   TRANSPLANT INTERNATIONAL

Hydrogen Sulfide Protects Against High Glucose-Induced Human Umbilical Vein Endothelial Cell Injury Through Activating PI3K/Akt/eNOS Pathway

(2020) Fengxia Lin et al.   Drug Design Development and Therapy

Hydrogen Sulfide Impairs Meiosis Resumption in Xenopus laevis Oocytes

(2020) Armance Gelaude et al.   Cells

Hydrogen Sulfide in Pharmacotherapy, Beyond the Hydrogen Sulfide-Donors

(2020) Ewelina Zaorska et al.   Biomolecules

Hydrogen sulfide rescues high glucose-induced migration dysfunction in HUVECs by upregulating miR-126-3p

(2020) Wen-long Xue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

H2S stimulated bioenergetics in chicken erythrocytes and the underlying mechanism

(2020) Zhuping Jin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

SG1002 AND CATENATED DIVALENT ORGANIC SULFUR COMPOUNDS AS PROMISING HYDROGEN SULFIDE PRODRUGS

(2020) Gabriel Gojon et al.   ANTIOXIDANTS & REDOX SIGNALING

A Metabolic Roadmap for Somatic Stem Cell Fate

(2020) C. Hai Ly et al.   Cell Metabolism

Possible application of H2S-producing compounds in therapy of coronavirus (COVID-19) infection and pneumonia

(2020) Mikhail B. Evgen’ev et al.   CELL STRESS & CHAPERONES

Nitric oxide and hydrogen sulfide: a nice pair in the respiratory system

(2020) Salvatore Fuschillo et al.   CURRENT MEDICINAL CHEMISTRY

CRY1‐CBS binding regulates circadian clock function and metabolism

(2020) Sibel Cal‐Kayitmazbatir et al.   FEBS Journal

Sa1538 PREEMPTIVE DAA THERAPY AS PROPHYLAXIS IN DONOR HCV-POSITIVE TO RECIPIENT HCV-NEGATIVE SOLID ORGAN TRANSPLANT: A COMPREHENSIVE REVIEW

(2020) Meher Sindhoora Mavuram et al.   GASTROENTEROLOGY

Hydrogen sulfide alleviates liver injury via S-sulfhydrated-Keap1/Nrf2/LRP1 pathway

(2020) Shuang Zhao et al.   HEPATOLOGY

H2S counteracts proinflammatory effects of LPS through modulation of multiple pathways in human cells

(2020) M. M. Yurinskaya et al.   INFLAMMATION RESEARCH

The Roles of NO and H2S in Sperm Biology: Recent Advances and New Perspectives

(2020) Martin Kadlec et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

New Insights into Molecular Links Between Microbiota and Gastrointestinal Cancers: A Literature Review

(2020) Yash Raj Rastogi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Thioredoxin regulates human mercaptopyruvate sulfurtransferase at physiologically-relevant concentrations

(2020) Pramod Kumar Yadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen Sulfide Therapy Suppresses Cofilin-2 and Attenuates Ischemic Heart Failure in a Mouse Model of Myocardial Infarction

(2020) Khoa Nguyen et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

The role of mitochondrial reactive oxygen species, NO and H 2 S in ischaemia/reperfusion injury and cardioprotection

(2020) Ioanna Andreadou et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cystathionine gamma-lyase aggravates periodontal damage in traumatic occlusion mouse models

(2020) Liyuan Chen et al.   JOURNAL OF PERIODONTAL RESEARCH

The Peculiar Facets of Nitric Oxide as a Cellular Messenger: From Disease-Associated Signaling to the Regulation of Brain Bioenergetics and Neurovascular Coupling

(2020) João Laranjinha et al.   NEUROCHEMICAL RESEARCH

Divergent effect of fast- and slow-releasing H2S donors on boar spermatozoa under oxidative stress

(2020) Eliana Pintus et al.   Scientific Reports

Mechanical load-induced H2S production by periodontal ligament stem cells activates M1 macrophages to promote bone remodeling and tooth movement via STAT1

(2020) Danqing He et al.   Stem Cell Research & Therapy

Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice

(2020) Stephen E. Wilkie et al.   GeroScience

Role of 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics in Murine Colon Cancer Cells

(2020) Fiona Augsburger et al.   Biomolecules

Cystathionine-β-synthase: Molecular Regulation and Pharmacological Inhibition

(2020) Karim Zuhra et al.   Biomolecules

H2S as a potential defense against COVID-19?

(2020) Guangdong Yang   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Alleviating Cellular Oxidative Stress through Treatment with Superoxide‐Triggered Persulfide Prodrugs

(2020) Yin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

ON H2S PRODRUGS

(2020) Gabriel Gojon   ANTIOXIDANTS & REDOX SIGNALING

Modulation of acid-sensing ion channels by hydrogen sulfide

(2020) Mohona Mukhopadhyay et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Unraveling the role of thiosulfate sulfurtransferase in metabolic diseases

(2020) Paul D. Kruithof et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Anti‐inflammatory and antiviral roles of hydrogen sulfide: rationale for considering H 2 S‐donors in COVID‐19 therapy

(2020) Valentina Citi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Relaxing Effect of Hydrogen Sulfide on Isolated Bovine Mesenteric Lymph Nodes

(2020) G. I. Lobov   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

The Role of Hydrogen Sulfide in the Dilatation of Mesenteric Lymphatic Vessels in Bulls

(2020) G. I. Lobov   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

NaSH increases SIRT1 activity and autophagy flux through sulfhydration to protect SH-SY5Y cells induced by MPP~+

(2020) Jing Li et al.   CELL CYCLE

Protective effect of exogenous hydrogen sulfide on diaphragm muscle fibrosis in streptozotocin-induced diabetic rats

(2020) Rui Yang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Cystathionine beta synthase regulates mitochondrial dynamics and function in endothelial cells

(2020) Geeta Rao et al.   FASEB JOURNAL

Hypersensitivity of Airway Reflexes Induced by Hydrogen Sulfide: Role of TRPA1 Receptors

(2020) Chi-Li Chung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hydrogen Sulfide Treatment Improves Post-Infarct Remodeling and Long-Term Cardiac Function in CSE Knockout and Wild-Type Mice

(2020) Leigh J. Ellmers et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Physiological dynamics of chemosynthetic symbionts in hydrothermal vent snails

(2020) Corinna Breusing et al.   ISME Journal

Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S‐sulfhydration

(2020) Fangping Lu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Trophoblast H2S maintains early pregnancy via regulating maternal-fetal interface immune hemostasis

(2020) Banqin Wang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Nitric oxide is fundamental to neurovascular coupling in humans

(2020) Ryan L. Hoiland et al.   JOURNAL OF PHYSIOLOGY-LONDON

Aggregation Enhanced Responsiveness of Rationally Designed Probes to Hydrogen Sulfide for Targeted Cancer Imaging

(2020) Rongchen Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrogen sulfide: an endogenous regulator of the immune system

(2020) Nahzli Dilek et al.   PHARMACOLOGICAL RESEARCH

Beyond the cell factory: Homeostatic regulation of and by the UPRER

(2020) Melissa G. Metcalf et al.   Science Advances

Cystitis-Related Bladder Pain Involves ATP-Dependent HMGB1 Release from Macrophages and Its Downstream H2S/Cav3.2 Signaling in Mice

(2020) Shiori Hiramoto et al.   Cells

Cysteine as a Carbon Source, a Hot Spot in Cancer Cells Survival

(2020) Jacinta Serpa   Frontiers in Oncology

Hydrogen sulfide inhibits aortic valve calcification in heart via regulating RUNX2 by NF-κB, a link between inflammation and mineralization

(2020) Katalin Éva Sikura et al.   Journal of Advanced Research

Hypermethioninemia Leads to Fatal Bleeding and Increased Mortality in a Transgenic I278T Mouse Model of Homocystinuria

(2020) Insun Park et al.   Biomedicines

Hydrogen Sulfide Accumulates LDL Receptor Precursor via Downregulating PCSK9 in HepG2 Cells

(2020) Yong Huang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

3-Mercaptopyruvate sulfurtransferase/hydrogen sulfide protects cerebral endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury via mitoprotection and inhibition of the RhoA/ROCK pathway

(2020) Fang Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Effect of Hydrogen Sulfide on Deformability of Rat Erythrocytes

(2020) O. E. Fadyukova et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

CD4 + T-Cell Endogenous Cystathionine γ Lyase-Hydrogen Sulfide Attenuates Hypertension by Sulfhydrating Liver Kinase B1 to Promote T Regulatory Cell Differentiation and Proliferation

(2020) Changting Cui et al.   CIRCULATION

Role of hydrogen sulfide and polysulfides in neurological diseases: focus on protein S-Persulfidation

(2020) Hai-Jian Sun et al.   Current Neuropharmacology

Interaction among estrogen, IGF-1, and H2S on smooth muscle cell proliferation

(2020) Tian Shuang et al.   JOURNAL OF ENDOCRINOLOGY

Relaxant effect of diallyl sulfide on nonpregnant rat uterus: Involvement of voltage‐dependent calcium channels

(2020) Oğuzhan E. Efe et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Increased expression of cystathionine beta-synthase and chemokine ligand 21 is closely associated with poor prognosis in extrahepatic cholangiocarcinoma

(2020) Lingxiang Wang et al.   MEDICINE

The role of host defences in Covid 19 and treatments thereof

(2020) Maurizio Dattilo   MOLECULAR MEDICINE

Poly(ADP-ribose) polymerase inhibition: past, present and future

(2020) Nicola J. Curtin et al.   NATURE REVIEWS DRUG DISCOVERY

Role of hydrogen sulfide in cardiovascular ageing

(2020) Lara Testai et al.   PHARMACOLOGICAL RESEARCH

Estrogen Regulates Local Cysteine Metabolism in Mouse Myometrium

(2020) Damian D. Guerra et al.   Reproductive Sciences

Bioenergetic effects of hydrogen sulfide suppress soluble Flt-1 and soluble endoglin in cystathionine gamma-lyase compromised endothelial cells

(2020) Lissette Carolina Sanchez-Aranguren et al.   Scientific Reports

Endothelial Cell Cystathionine γ‐Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury

(2020) Huijing Xia et al.   Journal of the American Heart Association

Hydrogen Sulfide Alleviates Skeletal Muscle Fibrosis via Attenuating Inflammation and Oxidative Stress

(2020) Linlin Zhao et al.   Frontiers in Physiology

Understanding hydrogen sulfide signaling in neonatal airway disease

(2020) Marta Schiliro et al.   Expert Review of Respiratory Medicine

Enzymatic Regulation and Biological Functions of Reactive Cysteine Persulfides and Polysulfides

(2020) Tomohiro Sawa et al.   Biomolecules

Uterine Dysfunction in Diabetic Mice: The Role of Hydrogen Sulfide

(2020) Emma Mitidieri et al.   Antioxidants

Endogenous hydrogen sulfide maintains eupnea in an in situ arterially perfused preparation of rats

(2020) Minako Okazaki et al.   Communications Biology

Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress–autophagy axis and improves myocardial reconstruction after acute myocardial infarction

(2020) Yaling Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Simulated sleep apnea alters hydrogen sulfide regulation of blood flow and pressure

(2020) Adelaeda Barrera et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Exogenous hydrogen sulfide inhibits neutrophils extracellular traps formation via the HMGB1/TLR4/p-38 MAPK/ROS axis in hyperhomocysteinemia rats

(2020) Xueying Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cysteine metabolic circuitries: druggable targets in cancer

(2020) Vasco D. B. Bonifácio et al.   BRITISH JOURNAL OF CANCER

Mapping the Endothelial Cell S -Sulfhydrome Highlights the Crucial Role of Integrin Sulfhydration in Vascular Function

(2020) Sofia-Iris Bibli et al.   CIRCULATION

Hydrogen sulfide induces Ca2+ release from the endoplasmic reticulum and suppresses ATP-induced Ca2+ signaling in rat spinal cord astrocytes

(2020) Takeshi Nii et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Proteomic exploration of cystathionine β-synthase deficiency: implications for the clinic

(2020) Hieronim Jakubowski   Expert Review of Proteomics

The mitochondria‐targeted hydrogen sulfide donor AP39 improves health and mitochondrial function in a C. elegans primary mitochondrial disease model

(2020) Bridget C. Fox et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Hydrogen sulfide: A versatile gaseous molecule in plants

(2020) Yamshi Arif et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Hydrogen sulfide attenuates postoperative cognitive dysfunction through promoting the pathway of Warburg effect-synaptic plasticity in hippocampus

(2020) Si-Min Chen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Roles of Hydrogen Sulfide Donors in Common Kidney Diseases

(2020) Ebenezeri Erasto Ngowi et al.   Frontiers in Pharmacology

Hydrogen Sulfide Attenuates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Inhibiting Apoptosis and Promoting Autophagy via Reactive Oxygen Species/Phosphatidylinositol 3-Kinase/AKT/Mammalian Target of Rapamycin Signaling Pathway

(2020) Dongdong Wu et al.   Frontiers in Pharmacology

Decreased bioavailability of hydrogen sulfide links vascular endothelium and atrial remodeling in atrial fibrillation

(2020) Megan Watts et al.   Redox Biology

Effects of hydrogen sulfide on mitochondrial function and cellular bioenergetics

(2020) Bindu D. Paul et al.   Redox Biology

Hydrogen sulfide and DNA repair

(2020) Rodney Shackelford et al.   Redox Biology

Role of Hydrogen Sulfide and 3-Mercaptopyruvate Sulfurtransferase in the Regulation of the Endoplasmic Reticulum Stress Response in Hepatocytes

(2020) Theodora Panagaki et al.   Biomolecules

The Potential Role of Hydrogen Sulfide in the Regulation of Cerebrovascular Tone

(2020) Eleni Dongó et al.   Biomolecules

Ethylmalonic encephalopathy: Clinical course and therapy response in an uncommon mild case with a severe ETHE1 mutation

(2020) Melike Ersoy et al.   Molecular Genetics and Metabolism Reports

The multifaceted roles of sulfane sulfur species in cancer-associated processes

(2020) Karim Zuhra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Hydrogen sulfide guards myoblasts from ferroptosis by inhibiting ALOX12 acetylation

(2020) Yuehong Wang et al.   CELLULAR SIGNALLING

Hydrogen sulfide as a novel biomarker of asthma and chronic obstructive pulmonary disease

(2020) Yasuhito Suzuki et al.   ALLERGOLOGY INTERNATIONAL

Cystathionine γ-lyase promotes estrogen-stimulated uterine artery blood flow via glutathione homeostasis

(2020) Rachael Bok et al.   Redox Biology

3-mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics

(2019) Armita Abdollahi Govar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cbs overdosage is necessary and sufficient to induce cognitive phenotypes in mouse models of Down syndrome and interacts genetically with Dyrk1a

(2019) Damien Marechal et al.   HUMAN MOLECULAR GENETICS

Effect of 3-mercaptopyruvate sulfurtransferase deficiency on the development of multiorgan failure, inflammation and wound healing in mice subjected to burn injury

(2019) Akbar Ahmad et al.   Journal of Burn Care & Research

NO acutely modulates hypothalamic and neurohypophyseal CO and H2 S production to control AVP, OT and ANP release in rats

(2019) Ricardo Coletti et al.   JOURNAL OF NEUROENDOCRINOLOGY

Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases

(2019) Antonio Cuadrado et al.   NATURE REVIEWS DRUG DISCOVERY

Hydrogen sulfide: a gaseous signaling molecule modulates tissue homeostasis: implications in ophthalmic diseases

(2019) Yuyi Han et al.   Cell Death & Disease

Hydrogen sulfide attenuates lung ischemia–reperfusion injury through SIRT3-dependent regulation of mitochondrial function in type 2 diabetic rats

(2019) Tao Jiang et al.   SURGERY

GYY4137 attenuates LPS-induced acute lung injury via heme oxygenase-1 modulation

(2019) Lei Jiang et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Expression and activity of hydrogen sulfide generating enzymes in murine macrophages stimulated with lipopolysaccharide and interferon-γ

(2019) Patrycja Bronowicka-Adamska et al.   MOLECULAR BIOLOGY REPORTS

Hydrogen sulfide modulates SIRT1 and suppresses oxidative stress in diabetic nephropathy

(2019) Hanan H. Ahmed et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Nitric oxide and hydrogen sulfide in plants: which comes first?

(2019) Francisco J Corpas et al.   JOURNAL OF EXPERIMENTAL BOTANY

Hydrogen sulfide attenuates homocysteine‐induced osteoblast dysfunction by inhibiting mitochondrial toxicity

(2019) Yuankun Zhai et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Saying NO to H2S: A Story of HNO, HSNO, and SSNO–

(2019) Ivana Ivanovic-Burmazovic et al.   INORGANIC CHEMISTRY

Hydrogen sulfide, reactive sulfur species and coping with reactive oxygen species

(2019) Kenneth R. Olson   FREE RADICAL BIOLOGY AND MEDICINE

Ovine Uterine Artery Hydrogen Sulfide Biosynthesis in vivo: Effects of Ovarian Cycle and Pregnancy

(2019) Thomas J Lechuga et al.   BIOLOGY OF REPRODUCTION

Hydrogen sulfide preconditioning could ameliorate reperfusion associated injury in diabetic cardiomyopathy rat heart through preservation of mitochondria

(2019) Mahalakshmi Ansari et al.   BIOCHIMIE

Hyperhomocysteinemia induced endothelial progenitor cells dysfunction through hyper-methylation of CBS promoter

(2019) Jyotirmaya Behera et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of hydrogen sulfide in cerebrovascular alteration during aging

(2019) Juyeon Mun et al.   ARCHIVES OF PHARMACAL RESEARCH

Hydrogen sulfide enhances the effectiveness of mesenchymal stem cell therapy in rats with heart failure: In vitro preconditioning versus in vivo co-delivery

(2019) Maha Abdelmonem et al.   BIOMEDICINE & PHARMACOTHERAPY

A proof‐of‐concept, Phase 2 clinical trial of the gastrointestinal safety of a hydrogen sulfide‐releasing anti‐inflammatory drug

(2019) John L. Wallace et al.   BRITISH JOURNAL OF PHARMACOLOGY

Anomalous K v 7 potassium channel activity in human Malignant Hyperthermia syndrome unmasks a key role for H 2 S and persulfidation in skeletal muscle

(2019) Valentina Vellecco et al.   BRITISH JOURNAL OF PHARMACOLOGY

HYDROGEN SULFIDE AND DERMATOLOGICAL DISEASES

(2019) Silvia A. Coavoy‐Sánchez et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hydrogen sulfide regulates muscle RING finger‐1 protein S‐sulfhydration at Cys 44 to prevent cardiac structural damage in diabetic cardiomyopathy

(2019) Xiaojiao Sun et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hydrogen Sulfide Lowers Hyperhomocysteinemia Dependent on Cystathionine γ Lyase S‐Sulfhydration in ApoE‐knockout Atherosclerotic Mice

(2019) Jinhui Fan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mitochondria Targeting Fluorescent Probes Based on Through Bond Energy Transfer for Mutually Imaging Signaling Molecules H2S and H2O2

(2019) Jian Sun et al.   CHEMISTRY-A EUROPEAN JOURNAL

Role of hydrogen sulfide in cognitive deficits: Evidences and mechanisms

(2019) Jin-Ting He et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Exogenous hydrogen sulphide supplement accelerates skin wound healing via oxidative stress inhibition and vascular endothelial growth factor enhancement

(2019) Mengting Xu et al.   EXPERIMENTAL DERMATOLOGY

Comparative localization of cystathionine beta synthases and cystathionine gamma lyase in canine, non-human primate and human retina

(2019) Alireza Badiei et al.   EXPERIMENTAL EYE RESEARCH

Impact of Pharmacological Inhibition of Hydrogen Sulphide Production in the SOD1G93A-ALS Mouse Model

(2019) Alida Spalloni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pharmacoepidemiological research for the development and evaluation of drugs in pediatrics

(2019) Florentia Kaguelidou et al.   THERAPIE

Hydrogen Sulfide Ameliorates Homocysteine-Induced Cardiac Remodeling and Dysfunction

(2019) Sumit Kar et al.   Frontiers in Physiology

Hydrogen Sulfide-releasing peptide hydrogel limits the development of intimal hyperplasia in human vein segments

(2019) Alban Longchamp et al.   Acta Biomaterialia

Supplementing preservation solution with mitochondria‐targeted H 2 S donor AP39 protects cardiac grafts from prolonged cold ischemia reperfusion injury in heart transplantation

(2019) Cuilin Zhu et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Developmental Cell Death in the Cerebral Cortex

(2019) Fong Kuan Wong et al.   Annual Review of Cell and Developmental Biology

S-Sulfhydration of SIRT3 by Hydrogen Sulfide Attenuates Mitochondrial Dysfunction in Cisplatin-Induced Acute Kidney Injury

(2019) Yujia Yuan et al.   ANTIOXIDANTS & REDOX SIGNALING

Angiotensin II downregulates vascular endothelial cell hydrogen sulfide production by enhancing cystathionine γ-lyase degradation through ROS-activated ubiquitination pathway

(2019) Lu Bai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of the gasotransmitter hydrogen sulfide in pathological calcification

(2019) Mariela Castelblanco et al.   BRITISH JOURNAL OF PHARMACOLOGY

A novel hydrogen sulfide-releasing donor, HA-ADT, suppresses the growth of human breast cancer cells through inhibiting the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK signaling pathways

(2019) Qian Dong et al.   CANCER LETTERS

Methionine restriction delays senescence and suppresses the senescence-associated secretory phenotype in the kidney through endogenous hydrogen sulfide

(2019) Si-Yang Wang et al.   CELL CYCLE

Potassium channels contribute to the increased sensitivity of the rabbit carotid artery to hydrogen sulfide in diabetes

(2019) José M. Centeno et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

EPR detection of sulfanyl radical during sulfhemoglobin formation – Influence of catalase

(2019) Augustin C. Mot et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cystathionine-Gamma-Lyase-Derived Hydrogen Sulfide-Regulated Substance P Modulates Liver Sieve Fenestrations in Caecal Ligation and Puncture-Induced Sepsis

(2019) Ravinder Gaddam et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Preeclampsia-Like Features and Partial Lactation Failure in Mice Lacking Cystathionine γ-Lyase—An Animal Model of Cystathioninuria

(2019) Noriyuki Akahoshi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hydrogen sulfide perturbs mitochondrial bioenergetics and triggers metabolic reprogramming in colon cells

(2019) Marouane Libiad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel mechanism of sildenafil improving the excessive proliferation and H2S production in pulmonary arterial smooth muscle cells

(2019) Zhenya Yao et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Altered neurovascular coupling and brain arginine metabolism in endothelial nitric oxide synthase deficient mice

(2019) Ashwini Hariharan et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Increase of cystathionine-γ-lyase (CSE) during late wound repair: Hydrogen sulfide triggers cytokeratin 10 expression in keratinocytes

(2019) Itamar Goren et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Fatty-acid receptor CD36 functions as a hydrogen sulfide-targeted receptor with its Cys333-Cys272 disulfide bond serving as a specific molecular switch to accelerate gastric cancer metastasis

(2019) Rui Wang et al.   EBioMedicine

Biological Effects of Thermal Water-Associated Hydrogen Sulfide on Human Airways and Associated Immune Cells: Implications for Respiratory Diseases

(2019) Joana Viegas et al.   Frontiers in Public Health

Hydrogen sulfide is a novel regulator implicated in glucocorticoids-inhibited bone formation

(2019) Jun Ma et al.   Aging-US

Exogenous H2S reduces the acetylation levels of mitochondrial respiratory enzymes via regulating the NAD+-SIRT3 pathway in cardiac tissues of db/db mice

(2019) Yu Sun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Activatable Small Molecule H2S Donors

(2019) Carolyn M Levinn et al.   ANTIOXIDANTS & REDOX SIGNALING

A novel possible role for met hemoglobin as carrier of H2S in the blood

(2019) Birgitte Jensen et al.   ANTIOXIDANTS & REDOX SIGNALING

Direct Proteomic Mapping of Cysteine Persulfidation

(2019) Ling Fu et al.   ANTIOXIDANTS & REDOX SIGNALING

HEMEPROTEINS AS TARGETS FOR SULFIDE SPECIES

(2019) Fernando Martín Boubeta et al.   ANTIOXIDANTS & REDOX SIGNALING

Modulation of myeloid derived suppressor cells (MDSCs) functions: a new strategy towards hydrogen sulfide anti‐cancer effects

(2019) Paola De Cicco et al.   BRITISH JOURNAL OF PHARMACOLOGY

H2S-Mediated Changes in Erythrocyte Volume: Role of Gardos Channels, Na+,K+,2Cl— Cotransport and Anion Exchanger

(2019) Yu. G. Birulina et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Hydrogen sulfide impacts on inflammation-induced adipocyte dysfunction

(2019) Ferran Comas et al.   FOOD AND CHEMICAL TOXICOLOGY

Hydrogen sulfide modulates IL-6/STAT3 pathway and inhibits oxidative stress, inflammation, and apoptosis in rat model of methotrexate hepatotoxicity

(2019) AA Fouad et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Hydrogen sulfide inhibits apoptosis and protects the bronchial epithelium in an allergic inflammation mice model

(2019) Jackeline A. Mendes et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mechanisms of hypoxia signalling: new implications for nephrology

(2019) Johannes Schödel et al.   Nature Reviews Nephrology

The gasotransmitter hydrogen sulfide inhibits transepithelial anion secretion of pregnant mouse endometrial epithelium

(2019) Jia-Wen Xu et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Overproduction of H2S, generated by CBS, inhibits mitochondrial Complex IV and suppresses oxidative phosphorylation in Down syndrome

(2019) Theodora Panagaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux via Up-regulation of SIRT1

(2019) Lei Wu et al.   Frontiers in Molecular Neuroscience

N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells

(2019) Karim Zuhra et al.   Cells

DNA-Capped Silver Nanoflakes as Fluorescent Nanosensor for Highly Sensitive Imaging of Endogenous H2S in Cell Division Cycles

(2019) Sitao Xie et al.   ANALYTICAL CHEMISTRY

Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis

(2019) Katalin Módis et al.   BIOCHEMICAL PHARMACOLOGY

Novel H2S-Releasing hydrogel for wound repair via in situ polarization of M2 macrophages

(2019) Jiang Wu et al.   BIOMATERIALS

Chronic administration of NaHS and L-Cysteine restores cardiovascular changes induced by high-fat diet in rats

(2019) Carolina B. Gomez et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hydrogen sulfide: a target to modulate oxidative stress and neuroplasticity for the treatment of pathological anxiety

(2019) Mary Chen et al.   Expert Review of Neurotherapeutics

The effects of intravitreal H 2 S application on apoptosis in the retina and cornea in experimental glaucoma model

(2019) Zuleyha Erisgin et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Hydrogen Sulfide in Bone Tissue Regeneration and Repair: State of the Art and New Perspectives

(2019) Laura Gambari et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

17β-Estradiol nongenomically induces vascular endothelial H2S release by promoting phosphorylation of cystathionine γ-lyase

(2019) Xingyan Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATP-sensitive K+ channels and mitochondrial permeability transition pore mediate effects of hydrogen sulfide on cytosolic Ca2+ homeostasis and insulin secretion in β-cells

(2019) Aizhu Lu et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Rational Design of a Targetable Fluorescent Probe for Visualizing H2S Production under Golgi Stress Response Elicited by Monensin

(2019) Hanchuang Zhu et al.   ANALYTICAL CHEMISTRY

Golgi Stress Response, Hydrogen Sulfide Metabolism, and Intracellular Calcium Homeostasis

(2019) Yanjie Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Altered dynamics in the circadian oscillation of clock genes in serum-shocked NIH-3T3 cells by the treatment of GYY4137 or AOAA

(2019) Maria Romerowicz-Misielak et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The protective effects of hydrogen sulfide on the myocardial ischemia via regulating Bmal1

(2019) Jiaqin Hu et al.   BIOMEDICINE & PHARMACOTHERAPY

Activation of the reverse transsulfuration pathway through NRF2/CBS confers erastin-induced ferroptosis resistance

(2019) Nan Liu et al.   BRITISH JOURNAL OF CANCER

Inhibition of hydrogen sulfide synthesis reverses acquired resistance to 5-FU through miR-215-5p-EREG/TYMS axis in colon cancer cells

(2019) Shanwen Chen et al.   CANCER LETTERS

A Central Role for the Gasotransmitter H2S in Aging

(2019) Rafael de Cabo et al.   Cell Metabolism

Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration

(2019) Jasmina Zivanovic et al.   Cell Metabolism

H2S alleviates renal injury and fibrosis in response to unilateral ureteral obstruction by regulating macrophage infiltration via inhibition of NLRP3 signaling

(2019) Yueyuan Zhou et al.   EXPERIMENTAL CELL RESEARCH

Hydrogen sulfide signaling in mitochondria and disease

(2019) Brennah Murphy et al.   FASEB JOURNAL

Propargylglycine decreases neuro-immune interaction inducing pain response in temporomandibular joint inflammation model

(2019) Emanuela G. Garattini et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Shear stress regulates cystathionine γ lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation

(2019) Sofia-Iris Bibli et al.   Redox Biology

Exercise Training Promotes Cardiac Hydrogen Sulfide Biosynthesis and Mitigates Pyroptosis to Prevent High-Fat Diet-Induced Diabetic Cardiomyopathy

(2019) Sumit Kar et al.   Antioxidants

The Inhibitory Effects of Slow-Releasing Hydrogen Sulfide Donors in the Mechanical Allodynia, Grip Strength Deficits, and Depressive-Like Behaviors Associated with Chronic Osteoarthritis Pain

(2019) Gerard Batallé et al.   Antioxidants

Cystathionine gamma lyase aggravates orthodontic root resorption in mice

(2019) Caizhu Lu et al.   Annals of Translational Medicine

Cytochrome c Reduction by H2S Potentiates Sulfide Signaling

(2018) Victor Vitvitsky et al.   ACS Chemical Biology

Coronary artery hypoxic vasorelaxation is augmented by perivascular adipose tissue through a mechanism involving hydrogen sulphide and cystathionine-β-synthase

(2018) J. Donovan et al.   Acta Physiologica

Mitochondria-targeted hydrogen sulfide attenuates endothelial senescence by selective induction of splicing factors HNRNPD and SRSF2

(2018) Eva Latorre et al.   Aging-US

Low Plasma Hydrogen Sulfide Is Associated with Impaired Renal Function and Cardiac Dysfunction

(2018) Qing Kuang et al.   AMERICAN JOURNAL OF NEPHROLOGY

Reduced Expression of Hydrogen Sulfide–Generating Enzymes Down-Regulates 15-Hydroxyprostaglandin Dehydrogenase in Chorion during Term and Preterm Labor

(2018) Qianqian Sun et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of reactive oxygen species and sulfide-quinone oxoreductase in hydrogen sulfide-induced contraction of rat pulmonary arteries

(2018) Jesus Prieto-Lloret et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A Hibernation-Like State for Transplantable Organs: Is Hydrogen Sulfide Therapy the Future of Organ Preservation?

(2018) George J. Dugbartey et al.   ANTIOXIDANTS & REDOX SIGNALING

Sulfhydrated Sirtuin-1 Increasing Its Deacetylation Activity Is an Essential Epigenetics Mechanism of Anti-Atherogenesis by Hydrogen Sulfide

(2018) Congkuo Du et al.   ANTIOXIDANTS & REDOX SIGNALING

A Review of Hydrogen Sulfide Synthesis, Metabolism, and Measurement: Is Modulation of Hydrogen Sulfide a Novel Therapeutic for Cancer?

(2018) Xu Cao et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide-Releasing Therapeutics: Translation to the Clinic

(2018) John L. Wallace et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide As a Potential Target in Preventing Spermatogenic Failure and Testicular Dysfunction

(2018) Jing Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Dietary and Endocrine Regulation of Endogenous Hydrogen Sulfide Production: Implications for Longevity

(2018) Christopher Hine et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of silent information regulator 1 in the protective effect of hydrogen sulfide on homocysteine-induced cognitive dysfunction: Involving reduction of hippocampal ER stress

(2018) Yi-Yun Tang et al.   BEHAVIOURAL BRAIN RESEARCH

Cystathionine gamma lyase-H 2 S contributes to osteoclastogenesis during bone remodeling induced by mechanical loading

(2018) Shenzheng Mo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hydrogen sulfide as a regulatory factor in kidney health and disease

(2018) Balakuntalam S. Kasinath et al.   BIOCHEMICAL PHARMACOLOGY

A review of hydrogen sulfide (H 2 S) donors: Chemistry and potential therapeutic applications

(2018) Chadwick R. Powell et al.   BIOCHEMICAL PHARMACOLOGY

Gasotransmitter hydrogen sulfide signaling in neuronal health and disease

(2018) Bindu D. Paul et al.   BIOCHEMICAL PHARMACOLOGY

Hydrogen sulfide in the regulation of insulin secretion and insulin sensitivity: Implications for the pathogenesis and treatment of diabetes mellitus

(2018) Jerzy Bełtowski et al.   BIOCHEMICAL PHARMACOLOGY

Investigations on the role of hemoglobin in sulfide metabolism by intact human red blood cells

(2018) Christopher L. Bianco et al.   BIOCHEMICAL PHARMACOLOGY

The dichotomous role of H 2 S in cancer cell biology? Déjà vu all over again

(2018) Khosrow Kashfi   BIOCHEMICAL PHARMACOLOGY

A timeline of hydrogen sulfide (H 2 S) research: From environmental toxin to biological mediator

(2018) Csaba Szabo   BIOCHEMICAL PHARMACOLOGY

Drug resistance induces the upregulation of H 2 S-producing enzymes in HCT116 colon cancer cells

(2018) Ashley A. Untereiner et al.   BIOCHEMICAL PHARMACOLOGY

Cross-talk between hydrogen sulfide and carbon monoxide in the mechanism of experimental gastric ulcers healing, regulation of gastric blood flow and accompanying inflammation

(2018) Marcin Magierowski et al.   BIOCHEMICAL PHARMACOLOGY

Cystathionine gamma-lyase/hydrogen sulfide system is essential for adipogenesis and fat mass accumulation in mice

(2018) Guangdong Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cystathionine beta synthase-hydrogen sulfide system in paraventricular nucleus reduced high fatty diet induced obesity and insulin resistance by brain-adipose axis

(2018) Fengjiao Zheng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Protective effect of exogenous hydrogen sulfide on pulmonary artery endothelial cells by suppressing endoplasmic reticulum stress in a rat model of chronic obstructive pulmonary disease

(2018) Hai-Bo Ding et al.   BIOMEDICINE & PHARMACOTHERAPY

Hydrogen sulfide inhibits ATP-induced neuroinflammation and Aβ 1–42 synthesis by suppressing the activation of STAT3 and cathepsin S

(2018) Lei Cao et al.   BRAIN BEHAVIOR AND IMMUNITY

Multiple role of 3-mercaptopyruvate sulfurtransferase: antioxidative function, H2 S and polysulfide production and possible SOx production

(2018) Noriyuki Nagahara   BRITISH JOURNAL OF PHARMACOLOGY

Eicosanoids in the gastrointestinal tract

(2018) John L Wallace   BRITISH JOURNAL OF PHARMACOLOGY

Persulfide synthases that are functionally coupled with translation mediate sulfur respiration in mammalian cells

(2018) Shigemoto Fujii et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regulators of the Transsulfuration Pathway

(2018) Juan I Sbodio et al.   BRITISH JOURNAL OF PHARMACOLOGY

Methylene Blue Counteracts H2S-Induced Cardiac Ion Channel Dysfunction and ATP Reduction

(2018) Joseph Y. Cheung et al.   Cardiovascular Toxicology

Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H 2 S Production

(2018) Alban Longchamp et al.   CELL

Impairment of an Endothelial NAD + -H 2 S Signaling Network Is a Reversible Cause of Vascular Aging

(2018) Abhirup Das et al.   CELL

Reactive oxygen radicals and gaseous transmitters in carotid body activation by intermittent hypoxia

(2018) Nanduri R. Prabhakar et al.   CELL AND TISSUE RESEARCH

Cystathionine-γ-lyase ameliorates the histone demethylase JMJD3-mediated autoimmune response in rheumatoid arthritis

(2018) Weijun Wu et al.   Cellular & Molecular Immunology

Endogenous Hydrogen Sulfide Ameliorates NOX4 Induced Oxidative Stress in LPS-Stimulated Macrophages and Mice

(2018) Xi-Ling Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

NaHS restores mitochondrial function and inhibits autophagy by activating the PI3K/Akt/mTOR signalling pathway to improve functional recovery after traumatic brain injury

(2018) Kebin Xu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

H 2 S induces Th1/Th2 imbalance with triggered NF-κB pathway to exacerbate LPS-induce chicken pneumonia response

(2018) Wei Wang et al.   CHEMOSPHERE

Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein HuR to Preserve Endothelial Cell Function and Delay Atherogenesis

(2018) Sofia-Iris Bibli et al.   CIRCULATION

Sputum-to-serum hydrogen sulphide ratio as a novel biomarker of predicting future risks of asthma exacerbation

(2018) Y. Suzuki et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Long-term exercise restores hydrogen sulfide in the kidney and contributes to exercise benefits in 5/6 nephrectomized rats

(2018) Behjat Seifi et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Hydrogen sulfide in physiological and pathological mechanisms in brain

(2018) Mohit Kumar et al.   CNS & Neurological Disorders-Drug Targets

The role of hydrogen sulfide and H2S-donors in myocardial protection against ischemia/reperfusion injury.

(2018) Valentina Citi et al.   CURRENT MEDICINAL CHEMISTRY

NaHS prejunctionally inhibits the cardioaccelerator sympathetic outflow in pithed rats

(2018) David Centurión et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Exogenous hydrogen sulfide protects from endothelial cell damage, platelet activation, and neutrophils extracellular traps formation in hyperhomocysteinemia rats

(2018) Ziqing Zhao et al.   EXPERIMENTAL CELL RESEARCH

Hydrogen sulfide supplement attenuates the apoptosis of retinal ganglion cells in experimental glaucoma

(2018) Shouyue Huang et al.   EXPERIMENTAL EYE RESEARCH

Cystathionine β-synthase regulates mitochondrial morphogenesis in ovarian cancer

(2018) Prabir Kumar Chakraborty et al.   FASEB JOURNAL

Hydrogen sulfide increases glutathione biosynthesis, and glucose uptake and utilisation in C2C12 mouse myotubes

(2018) Rajesh Parsanathan et al.   FREE RADICAL RESEARCH

Plasma cystathionine and risk of acute myocardial infarction among patients with coronary heart disease: Results from two independent cohorts

(2018) Indu Dhar et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Hydrogen sulfide in physiology and pathogenesis of bacteria and viruses

(2018) Virender Kumar Pal et al.   IUBMB LIFE

Allosteric control of human cystathionine β-synthase activity by a redox active disulfide bond

(2018) Weining Niu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2)

(2018) Junghoon Ha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Volatile sulfur compounds in tropical fruits

(2018) Robert J. Cannon et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Reactions of ferric hemoglobin and myoglobin with hydrogen sulfide under physiological conditions

(2018) Birgitte Jensen et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Hydrogen sulfide regulates cardiac mitochondrial biogenesis via the activation of AMPK

(2018) Yuuki Shimizu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Reduction of hydrogen sulfide synthesis enzymes cystathionine-β-synthase and cystathionine-γ-lyase in the colon of patients with Hirschsprungs disease

(2018) Christian Tomuschat et al.   JOURNAL OF PEDIATRIC SURGERY

Charge Transfer and π to π* Transitions in the Visible Spectra of Sulfheme Met Isomeric Structures

(2018) Hector D. Arbelo-López et al.   JOURNAL OF PHYSICAL CHEMISTRY B

BDNF/TrkB Pathway Mediates the Antidepressant-Like Role of H2S in CUMS-Exposed Rats by Inhibition of Hippocampal ER Stress

(2018) Le Wei et al.   NEUROMOLECULAR MEDICINE

Mercaptopyruvate acts as endogenous vasodilator independently of 3-mercaptopyruvate sulfurtransferase activity

(2018) Emma Mitidieri et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

AMPK activation promotes gastroprotection through mutual interaction with the gaseous mediators H 2 S, NO, and CO

(2018) Simone de Araújo et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydrogen sulphide facilitates exocytosis by regulating the handling of intracellular calcium by chromaffin cells

(2018) Ricardo de Pascual et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Anti-inflammatory effect of ATB-352, a H2S −releasing ketoprofen derivative, on lipopolysaccharide-induced periodontitis in rats

(2018) Enrico Gugliandolo et al.   PHARMACOLOGICAL RESEARCH

The therapeutic potential of cystathionine gamma-lyase in temporomandibular inflammation-induced orofacial hypernociception

(2018) Bruna M. Santos et al.   PHYSIOLOGY & BEHAVIOR

Golgi stress response reprograms cysteine metabolism to confer cytoprotection in Huntington’s disease

(2018) Juan I. Sbodio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Symbiotic Origin of Aging

(2018) Edward F. Greenberg et al.   REJUVENATION RESEARCH

The Effects of Genetic 3-Mercaptopyruvate Sulfurtransferase Deficiency in Murine Traumatic-Hemorrhagic Shock

(2018) Michael Gröger et al.   SHOCK

Broad spectrum proteomics analysis of the inferior colliculus following acute hydrogen sulfide exposure

(2018) Dong-Suk Kim et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Toxic effects and possible mechanisms of hydrogen sulfide and/or ammonia on porcine oocyte maturation in vitro

(2018) Lei-Lei Yang et al.   TOXICOLOGY LETTERS

Antitumor effect of sikokianin C, a selective cystathionine β-synthase inhibitor, against human colon cancer in vitro and in vivo

(2018) Weining Niu et al.   MedChemComm

Phosphodiesterase type 4 inhibition enhances nitric oxide- and hydrogen sulfide-mediated bladder neck inhibitory neurotransmission

(2018) Ángel Agis-Torres et al.   Scientific Reports

Exogenous hydrogen sulfide gas does not induce hypothermia in normoxic mice

(2018) Sebastiaan D. Hemelrijk et al.   Scientific Reports

Hydrogen sulfide promotes immunomodulation of gingiva-derived mesenchymal stem cells via the Fas/FasL coupling pathway

(2018) Ruili Yang et al.   Stem Cell Research & Therapy

Neutrophils use superoxide to control bacterial infection at a distance

(2018) Quang Tien Phan et al.   PLoS Pathogens

Hydrogen sulfide in diabetic complications: focus on molecular mechanisms

(2018) Ling-ling Qian et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Total sulfane sulfur bioavailability reflects ethnic and gender disparities in cardiovascular disease

(2018) Saurabh Rajpal et al.   Redox Biology

Metabolism of hydrogen sulfide (H 2 S) and Production of Reactive Sulfur Species (RSS) by superoxide dismutase

(2018) Kenneth R. Olson et al.   Redox Biology

Hydrogen sulfide ameliorates aging-associated changes in the kidney

(2018) Hak Joo Lee et al.   GeroScience

Hydrogen sulfide alleviates hyperhomocysteinemia-mediated skeletal muscle atrophy via mitigation of oxidative and endoplasmic reticulum stress injury

(2018) Avisek Majumder et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Reactive Sulfur Species Emerge as Gliotransmitters to Support Memory via Sulfuration-Dependent Gating of NR2A-Containing NMDA Receptor Function

(2018) Han Luo et al.   ANTIOXIDANTS & REDOX SIGNALING

Do nitric oxide, carbon monoxide and hydrogen sulfide really qualify as ‘gasotransmitters’ in bacteria?

(2018) Lauren K. Wareham et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Evolution of Hydrogen Sulfide Therapeutics to Treat Cardiovascular Disease

(2018) Zhen Li et al.   CIRCULATION RESEARCH

Transcriptome profiling and identification of functional genes involved in H2S response in grapevine tissue cultured plantlets

(2018) Qian Ma et al.   Genes & Genomics

Cerebroprotective effects of hydrogen sulfide in homocysteine-induced neurovascular permeability: Involvement of oxidative stress, arginase, and matrix metalloproteinase-9

(2018) Nibendu Nath et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Age- and sex-dependent alteration of functions and epigenetic modifications of vessel and endothelium related biomarkers

(2018) Sevtap HAN et al.   TURKISH JOURNAL OF BIOLOGY

A pharmacological probe identifies cystathionine β-synthase as a new negative regulator for ferroptosis

(2018) Li Wang et al.   Cell Death & Disease

Characterizations of complete hypersurfaces in locally symmetric Riemannian manifolds

(2018) Jogli G. Araújo et al.   COLLOQUIUM MATHEMATICUM

Hydrogen Sulfide Protects against Chemical Hypoxia-Induced Injury via Attenuation of ROS-Mediated Ca2+ Overload and Mitochondrial Dysfunction in Human Bronchial Epithelial Cells

(2018) Cai-Xia Liu et al.   Biomed Research International

Hydrogen Sulfide Ameliorates Blood-Spinal Cord Barrier Disruption and Improves Functional Recovery by Inhibiting Endoplasmic Reticulum Stress-Dependent Autophagy

(2018) Haoli Wang et al.   Frontiers in Pharmacology

Hydrogen Sulfide (H2S)-Releasing Compounds: Therapeutic Potential in Cardiovascular Diseases

(2018) Lei Zhang et al.   Frontiers in Pharmacology

Role of CSE-Produced H2S on Cerebrovascular Relaxation via RhoA-ROCK Inhibition and Cerebral Ischemia-Reperfusion Injury in Mice

(2018) Ji-Yue Wen et al.   ACS Chemical Neuroscience

Overexpression of CBS and CSE genes affects lifespan, stress resistance and locomotor activity in Drosophila melanogaster

(2018) Mikhail Shaposhnikov et al.   Aging-US

Metabolic resuscitation strategies to prevent organ dysfunction in sepsis

(2018) Vera Reitsema et al.   ANTIOXIDANTS & REDOX SIGNALING

Deficiency of the mitochondrial sulfide regulator ETHE1 disturbs cell growth, glutathione level and causes proteome alterations outside mitochondria

(2018) Navid Sahebekhtiari et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

E2β stimulates ovine uterine artery endothelial cell H2S production in vitro by estrogen receptor-dependent upregulation of cystathionine β-synthase and cystathionine γ-lyase expression†

(2018) Thomas J Lechuga et al.   BIOLOGY OF REPRODUCTION

Hydrogen sulfide and hepatic lipid metabolism - a critical pairing for liver health

(2018) Julie J Loiselle et al.   BRITISH JOURNAL OF PHARMACOLOGY

Restoration of skeletal muscle homeostasis by hydrogen sulfide during hyperhomocysteinemia-mediated oxidative/ER stress condition

(2018) Avisek Majumder et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

miR-191 secreted by platelet-derived microvesicles induced apoptosis of renal tubular epithelial cells and participated in renal ischemia-reperfusion injury via inhibiting CBS

(2018) Xiao-qiang Wu et al.   CELL CYCLE

Intramuscular cobinamide versus saline for treatment of severe hydrogen sulfide toxicity in swine

(2018) Patrick C. Ng et al.   CLINICAL TOXICOLOGY

Cysteine-derived hydrogen sulfide and gut health

(2018) François Blachier et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Cystathionine γ-lyase deficiency aggravates obesity-related insulin resistance via FoxO1-dependent hepatic gluconeogenesis

(2018) Wei Guo et al.   FASEB JOURNAL

Gas Signaling Molecules and Mitochondrial Potassium Channels

(2018) Agnieszka Walewska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hydrogen Sulfide: A Therapeutic Option in Systemic Sclerosis

(2018) Amaal Abdulle et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hydrogen sulfide alleviates uranium-induced rat hepatocyte cytotoxicity via inhibiting Nox4/ROS/p38 MAPK pathway

(2018) Juan Yi et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Estradiol-17β stimulates H2 S biosynthesis by ER-dependent CBS and CSE transcription in uterine artery smooth muscle cells in vitro

(2018) Thomas J. Lechuga et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The biologic effect of hydrogen sulfide and its function in various diseases

(2018) Qing Xiao et al.   MEDICINE

Evidence that thiol group modification and reactive oxygen species are involved in hydrogen sulfide-induced mitochondrial permeability transition pore opening in rat cerebellum

(2018) Leonardo de Moura Alvorcem et al.   MITOCHONDRION

The H2S Donor GYY4137 Stimulates Reactive Oxygen Species Generation in BV2 Cells While Suppressing the Secretion of TNF and Nitric Oxide

(2018) Milica Lazarević et al.   MOLECULES

H2S supplementation: A novel method for successful organ preservation at subnormothermic temperatures

(2018) Smriti Juriasingani et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Potential role of the 3-mercaptopyruvate sulfurtransferase (3-MST)—hydrogen sulfide (H2S) pathway in cancer cells

(2018) Fiona Augsburger et al.   PHARMACOLOGICAL RESEARCH

Methylene Blue Administration During and After Life-Threatening Intoxication by Hydrogen Sulfide:Efficacy Studies in Adult Sheep and Mechanisms of Action

(2018) Philippe Haouzi et al.   TOXICOLOGICAL SCIENCES

Molecular Basis for the Evolution of Species-Specific Hemoglobin Capture by Staphylococcus aureus

(2018) Jacob E. Choby et al.   mBio

Vascular Protection of Hydrogen Sulfide on Cerebral Ischemia/Reperfusion Injury in Rats

(2018) Ji-Yue Wen et al.   Frontiers in Neurology

Calcium sensing receptor initiating cystathionine-gamma-lyase/hydrogen sulfide pathway to inhibit platelet activation in hyperhomocysteinemia rat

(2017) Yuwen Wang et al.   EXPERIMENTAL CELL RESEARCH

Hydrogen sulfide reduces RAGE toxicity through inhibition of its dimer formation

(2017) Hong Zhou et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mechanisms of myeloperoxidase catalyzed oxidation of H 2 S by H 2 O 2 or O 2 to produce potent protein Cys-polysulfide-inducing species

(2017) Dorottya Garai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Analysis of endogenous H 2 S and H 2 S n in mouse brain by high-performance liquid chromatography with fluorescence and tandem mass spectrometric detection

(2017) Shin Koike et al.   FREE RADICAL BIOLOGY AND MEDICINE

DNA damage related crosstalk between the nucleus and mitochondria

(2017) Mohammad Saki et al.   FREE RADICAL BIOLOGY AND MEDICINE

Highly porous copper oxide sorbent for H 2 S capture at ambient temperature

(2017) Jian Wang et al.   FUEL

Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway

(2017) Meng Li et al.   GUT

Cystathionine β-synthase is required for body iron homeostasis

(2017) Yu-Fu Zhou et al.   HEPATOLOGY

Dexamethasone ameliorates H2S-induced acute lung injury by increasing claudin-5 expression via the PI3K pathway

(2017) P Geng et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Enzyme replacement therapy prevents loss of bone and fat mass in murine homocystinuria

(2017) Tomas Majtan et al.   HUMAN MUTATION

Impaired Hydrogen Sulfide–Mediated Vasodilation Contributes to Microvascular Endothelial Dysfunction in Hypertensive AdultsNovelty and Significance

(2017) Jody L. Greaney et al.   HYPERTENSION

Hydrogen Sulfide Exerts Anti-oxidative and Anti-inflammatory Effects in Acute Lung Injury

(2017) Kornelia K. Zimmermann et al.   INFLAMMATION

Excessive nNOS/NO/AMPK signaling activation mediated by the blockage of the CBS/H2S system contributes to oxygen-glucose deprivation-induced endoplasmic reticulum stress in PC12 cells

(2017) Rui Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Hydrogen sulfide inhibits NLRP3 inflammasome activation and reduces cytokine production bothin vitroand in a mouse model of inflammation

(2017) Mariela Castelblanco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen sulfide modulates eukaryotic translation initiation factor 2α (eIF2α) phosphorylation status in the integrated stress-response pathway

(2017) Vinita Yadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessment of H2Sin vivousing the newly developed mitochondria-targeted mass spectrometry probe MitoA

(2017) Sabine Arndt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Mechanistic Insights into Hemoglobin-catalyzed Hydrogen Sulfide Oxidation and the Fate of Polysulfide Products

(2017) Victor Vitvitsky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A distal ligand mutes the interaction of hydrogen sulfide with human neuroglobin

(2017) Markus Ruetz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of exogenous hydrogen sulfide on the proliferation and invasion of human Bladder cancer cells

(2017) Yang Li et al.   Journal of Cancer Research and Therapeutics

Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate

(2017) Ning Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Distinctive expression pattern of cystathionine-β-synthase and cystathionine-γ-lyase identifies mesenchymal stromal cells transition to mineralizing osteoblasts

(2017) Laura Gambari et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Urine metabolomics insight into acute kidney injury point to oxidative stress disruptions in energy generation and H2S availability

(2017) Marta Martin-Lorenzo et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Effects of Hydrogen Sulfide-Releasing Compounds on Aqueous Humor Outflow Facility in Porcine Ocular Anterior Segments,Ex Vivo

(2017) Jenaye Robinson et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Restoration of Rostral Ventrolateral Medulla Cystathionine-γLyase Activity Underlies Moxonidine-Evoked Neuroprotection and Sympathoinhibition in Diabetic Rats

(2017) Mohamed A. Fouda et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Mitochondria are not captive bacteria

(2017) Ajith Harish et al.   JOURNAL OF THEORETICAL BIOLOGY

Anti-inflammatory effects of H2S during acute bacterial infection: a review

(2017) Francesca Benedetti et al.   Journal of Translational Medicine

Hydrogen sulfide ameliorates acute lung injury induced by infrarenal aortic cross-clamping by inhibiting inflammation and angiopoietin 2 release

(2017) Bo Tang et al.   JOURNAL OF VASCULAR SURGERY

Sulfate-reducing bacteria stimulate gut immune responses and contribute to inflammation in experimental colitis

(2017) Vanessa Ribeiro Figliuolo et al.   LIFE SCIENCES

Candidate gene analysis of the fibrinogen phenotype reveals the importance of polygenic co-regulation

(2017) H. Toinét Cronjé et al.   MATRIX BIOLOGY

New mechanism of lipotoxicity in diabetic cardiomyopathy: Deficiency of Endogenous H 2 S Production and ER stress

(2017) Runmin Guo et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Toward Hydrogen Sulfide Based Therapeutics: Critical Drug Delivery and Developability Issues

(2017) Yueqin Zheng et al.   MEDICINAL RESEARCH REVIEWS

Protective effects of hydrogen sulfide against angiotensin II-induced endoplasmic reticulum stress in HUVECs

(2017) Heng-Jing Hu et al.   Molecular Medicine Reports

Hydrogen sulfide prevents homocysteine-induced endoplasmic reticulum stress in PC12 cells by upregulating SIRT-1

(2017) Chun-Yan Wang et al.   Molecular Medicine Reports

Hydrogen sulfide inhibits mitochondrial fission in neuroblastoma N2a cells through the Drp1/ERK1/2 signaling pathway

(2017) Peifeng Qiao et al.   Molecular Medicine Reports

Hydrogen sulfide protects against the development of experimental cerebral malaria in a C57BL/6 mouse model

(2017) Ping Jiang et al.   Molecular Medicine Reports

Hydrogen sulfide regulates bone remodeling and promotes orthodontic tooth movement

(2017) Haiya Pu et al.   Molecular Medicine Reports

Exogenous and Endogenous Hydrogen Sulfide Protects Gastric Mucosa against the Formation and Time-Dependent Development of Ischemia/Reperfusion-Induced Acute Lesions Progressing into Deeper Ulcerations

(2017) Marcin Magierowski et al.   MOLECULES

The role of metals in mammalian olfaction of low molecular weight organosulfur compounds

(2017) Eric Block et al.   NATURAL PRODUCT REPORTS

Exogenous hydrogen sulfide eliminates spatial memory retrieval impairment and hippocampal CA1 LTD enhancement caused by acute stress via promoting glutamate uptake

(2017) Jin He et al.   NEUROSCIENCE

Hydrogen Sulfide Specifically Alters NAD(P)H Quinone Dehydrogenase 1 (NQO1) Olfactory Neurons in the Rat

(2017) Fumiaki Imamura et al.   NEUROSCIENCE

Relevant variations and neuroprotecive effect of hydrogen sulfide in a rat glaucoma model

(2017) Shouyue Huang et al.   NEUROSCIENCE

Hydrogen sulfide inhibits giant depolarizing potentials and abolishes epileptiform activity of neonatal rat hippocampal slices

(2017) Aleksey V. Yakovlev et al.   NEUROSCIENCE

Anxiolytic-like effect of hydrogen sulfide (H2S) in rats exposed and re-exposed to the elevated plus-maze and open field tests

(2017) Alberto Ferreira Donatti et al.   NEUROSCIENCE LETTERS

Hydrogen sulfide protects against endoplasmic reticulum stress and mitochondrial injury in nucleus pulposus cells and ameliorates intervertebral disc degeneration

(2017) Daoliang Xu et al.   PHARMACOLOGICAL RESEARCH

Mechanism of H2S-mediated protection against oxidative stress inEscherichia coli

(2017) Alexander Mironov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complementary roles of gasotransmitters CO and H2S in sleep apnea

(2017) Ying-Jie Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Colorimetric detection of endogenous hydrogen sulfide production in living cells

(2017) Yong Jin Ahn et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Hydrogen sulfide in paraventricular nucleus attenuates blood pressure by regulating oxidative stress and inflammatory cytokines in high salt-induced hypertension

(2017) Yan-Feng Liang et al.   TOXICOLOGY LETTERS

A critical role for cystathionine-β-synthase in hydrogen sulfide-mediated hypoxic relaxation of the coronary artery

(2017) J. Donovan et al.   VASCULAR PHARMACOLOGY

Receptor Mechanisms Mediating the Pro-Nociceptive Action of Hydrogen Sulfide in Rat Trigeminal Neurons and Meningeal Afferents

(2017) Kseniya Koroleva et al.   Frontiers in Cellular Neuroscience

Discovery of selective cystathionine β-synthase inhibitors by high-throughput screening with a fluorescent thiol probe

(2017) Weining Niu et al.   MedChemComm

The expression of cystathionine gamma-lyase is regulated by estrogen receptor alpha in human osteoblasts

(2017) Elisabetta Lambertini et al.   Oncotarget

Hydrogen sulfide ameliorates cognitive dysfunction in streptozotocin-induced diabetic rats: involving suppression in hippocampal endoplasmic reticulum stress

(2017) Wei Zou et al.   Oncotarget

DNA hypomethylation of CBS promoter induced by folate deficiency is a potential noninvasive circulating biomarker for colorectal adenocarcinomas

(2017) Geng Xue et al.   Oncotarget

A Novel H2S-releasing Amino-Bisphosphonate which combines bone anti-catabolic and anabolic functions

(2017) Simona Rapposelli et al.   Scientific Reports

Broad-Range Antiviral Activity of Hydrogen Sulfide Against Highly Pathogenic RNA Viruses

(2017) Nikolay Bazhanov et al.   Scientific Reports

Exogenous H2S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes

(2017) Weiming Sun et al.   Cell and Bioscience

Nitric Oxide in the Pathogenesis and Treatment of Tuberculosis

(2017) Hamidreza Jamaati et al.   Frontiers in Microbiology

Electrophysiological Investigation of the Subcellular Fine Tuning of Sympathetic Neurons by Hydrogen Sulfide

(2017) Manuel Dominguez-Rodriguez et al.   Frontiers in Pharmacology

Role of Hydrogen Sulfide in Retinal Diseases

(2017) Jiantong Du et al.   Frontiers in Pharmacology

The Role of Hydrogen Sulfide on Cardiovascular Homeostasis: An Overview with Update on Immunomodulation

(2017) Li-Long Pan et al.   Frontiers in Pharmacology

Diurnal Fluctuations in Plasma Hydrogen Sulfide of the Mice

(2017) Sheng Jin et al.   Frontiers in Pharmacology

Hydrogen Sulfide Attenuates Atherosclerosis in a Partially Ligated Carotid Artery Mouse model via Regulating Angiotensin Converting Enzyme 2 Expression

(2017) Yanjun Lin et al.   Frontiers in Physiology

Hypoxia and hydrogen sulfide differentially affect normal and tumor-derived vascular endothelium

(2017) Serena Bianco et al.   Redox Biology

The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways

(2017) Xubo Chen et al.   Redox Biology

Effect of Physical Exercise on the Febrigenic Signaling is Modulated by Preoptic Hydrogen Sulfide Production

(2017) Jonatas E. Nogueira et al.   PLoS One

Pre- and posttreatment with hydrogen sulfide prevents ventilator-induced lung injury by limiting inflammation and oxidation

(2017) Simone Faller et al.   PLoS One

New method for quantification of gasotransmitter hydrogen sulfide in biological matrices by LC-MS/MS

(2017) Bo Tan et al.   Scientific Reports

3-Mercaptopyruvate sulfurtransferase produces potential redox regulators cysteine- and glutathione-persulfide (Cys-SSH and GSSH) together with signaling molecules H2S2, H2S3 and H2S

(2017) Yuka Kimura et al.   Scientific Reports

A turn-on endoplasmic reticulum-targeted two-photon fluorescent probe for hydrogen sulfide and bio-imaging applications in living cells, tissues, and zebrafish

(2017) Yonghe Tang et al.   Scientific Reports

The role of hydrogen sulfide in aging and age-related pathologies

(2016) Bernard Perridon et al.   Aging-US

Hydrogen sulfide promotes angiogenesis by downregulating miR-640 via the VEGFR2/mTOR pathway

(2016) Yu Zhou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Emerging role of hydrogen sulfide-microRNA crosstalk in cardiovascular diseases

(2016) Bryan T. Hackfort et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hydrogen sulfide-induced vasodilation mediated by endothelial TRPV4 channels

(2016) Jay S. Naik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

MPST but not CSE is the primary regulator of hydrogen sulfide production and function in the coronary artery

(2016) Maggie M. Kuo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hydrogen Sulfide Is an Antiviral and Antiinflammatory Endogenous Gasotransmitter in the Airways. Role in Respiratory Syncytial Virus Infection

(2016) Teodora Ivanciuc et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Hydrogen Sulfide Donors Activated by Reactive Oxygen Species

(2016) Yu Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Decreased Gluconeogenesis in the Absence of Cystathionine Gamma-Lyase and the Underlying Mechanisms

(2016) Ashley A. Untereiner et al.   ANTIOXIDANTS & REDOX SIGNALING

SIRT3 Mediates the Antioxidant Effect of Hydrogen Sulfide in Endothelial Cells

(2016) Liping Xie et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide Mitigates Myocardial Infarction via Promotion of Mitochondrial Biogenesis-Dependent M2 Polarization of Macrophages

(2016) Lei Miao et al.   ANTIOXIDANTS & REDOX SIGNALING

Endogenous hydrogen sulfide is involved in osteogenic differentiation in human periodontal ligament cells

(2016) Sheng-Dan Cen et al.   ARCHIVES OF ORAL BIOLOGY

Hydrogen sulfide promotes osteogenic differentiation of human periodontal ligament cells via p38-MAPK signaling pathway under proper tension stimulation

(2016) Zhaoxia Jiang et al.   ARCHIVES OF ORAL BIOLOGY

MicroRNA-186 promotes macrophage lipid accumulation and secretion of pro-inflammatory cytokines by targeting cystathionine γ-lyase in THP-1 macrophages

(2016) Yan Yao et al.   ATHEROSCLEROSIS

DNA methylation in cystathionine-γ-lyase (CSE) gene promoter induced by ox-LDL in macrophages and in apoE knockout mice

(2016) Hua-Ping Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cystathionine γ-lyase(CSE)/hydrogen sulfide system is regulated by miR-216a and influences cholesterol efflux in macrophages via the PI3K/AKT/ABCA1 pathway

(2016) Duo Gong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endogenous Hydrogen Sulfide Enhances Cell Proliferation of Human Gastric Cancer AGS Cells

(2016) Fumiko Sekiguchi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Effects of Dietary Selenium on Inflammation and Hydrogen Sulfide in the Gastrointestinal Tract in Chickens

(2016) Cong Wu et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Upregulation of cystathione β-synthase and p70S6K/S6 in neonatal hypoxic ischemic brain injury

(2016) Mirna Lechpammer et al.   BRAIN PATHOLOGY

Hydrogen sulfide depolarizes neurons in the nucleus of the solitary tract of the rat

(2016) Rishi Malik et al.   BRAIN RESEARCH

Cryogenic role of central endogenous hydrogen sulfide in the rat model of endotoxic shock

(2016) Rodrigo A.R. Fernández et al.   BRAIN RESEARCH

Real-time ultrasensitive VUV-PIMS detection of representative endogenous volatile markers in cancers

(2016) Zhen Li et al.   Cancer Biomarkers

Additive cardioprotection by pharmacological postconditioning with hydrogen sulfide and nitric oxide donors in mouse heart: S-sulfhydration vs. S-nitrosylation

(2016) Junhui Sun et al.   CARDIOVASCULAR RESEARCH

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice

(2016) Sarah J. Mitchell et al.   Cell Metabolism

H2S biosynthesis and catabolism: new insights from molecular studies

(2016) Peter Rose et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Involvement of microRNA-135a-5p in the Protective Effects of Hydrogen Sulfide Against Parkinson's Disease

(2016) Yuanyuan Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A practical guide to working with H2S at the interface of chemistry and biology

(2016) Matthew D. Hartle et al.   CHEMICAL SOCIETY REVIEWS

Protective effect of allyl methyl disulfide on acetaminophen-induced hepatotoxicity in mice

(2016) Yongchun Zhang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Restoration of Hydrogen Sulfide Production in Diabetic Mice Improves Reparative Function of Bone Marrow Cells

(2016) Zhongjian Cheng et al.   CIRCULATION

The Coronary Circulation as a Target of Cardioprotection

(2016) Gerd Heusch   CIRCULATION RESEARCH

Sodium Sulfide Attenuates Ischemic-Induced Heart Failure by Enhancing Proteasomal Function in an Nrf2-Dependent MannerCLINICAL PERSPECTIVE

(2016) Yuuki Shimizu et al.   Circulation-Heart Failure

New insights into coupling and uncoupling of cerebral blood flow and metabolism in the brain

(2016) Poornima Venkat et al.   CROATIAN MEDICAL JOURNAL

Pharmacological evidence that NaHS inhibits the vasopressor responses induced by stimulation of the preganglionic sympathetic outflow in pithed rats

(2016) David Centurión et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Upregulation of CBS/H2S system contributes to asymmetric dimethylarginine-triggered protection against the neurotoxicity of glutamate to PC12 cells by inhibiting NOS/NO pathway

(2016) Xiang-Yu Wang et al.   EXPERIMENTAL CELL RESEARCH

Hydrogen sulfide inhibits MPP+-induced aldehyde stress and endoplasmic reticulum stress in PC12 cells: involving upregulation of BDNF

(2016) Fan Xiao et al.   EXPERIMENTAL CELL RESEARCH

Cystathionine β-synthase regulates endothelial function via protein S-sulfhydration

(2016) Sounik Saha et al.   FASEB JOURNAL

Clues for discovering a new biological function of Vitreoscilla hemoglobin in organisms: potential sulfide receptor and storage

(2016) Dandan Wang et al.   FEBS LETTERS

Effects of CCK-8 and Cystathionine γ-Lyase/Hydrogen Sulfide System on Acute Lung Injury in Rats

(2016) Fengjun Tian et al.   INFLAMMATION

Effect of environmental exposure to hydrogen sulfide on central nervous system and respiratory function: a systematic review of human studies

(2016) Eunjung Lim et al.   INTERNATIONAL JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH

Diurnal Temporal Blood H2S Variations Correlate with the Circadian Rhythm of Vascular Contraction and Blood Pressure

(2016) Mecit Orhan Uludag et al.   International Journal of Pharmacology

Heme-dependent Metabolite Switching Regulates H2S Synthesis in Response to Endoplasmic Reticulum (ER) Stress

(2016) Omer Kabil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cystathionine-γ-lyase gene silencing with siRNA in monocytes/macrophages attenuates inflammation in cecal ligation and puncture-induced sepsis in the mouse

(2016) A Badiei et al.   JOURNAL OF BIOSCIENCES

Effect of exogenous hydrogen sulfide on gastric acid secretion

(2016) Hongzhao Sun et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

H2S protects against fatal myelosuppression by promoting the generation of megakaryocytes/platelets

(2016) Huan-Di Liu et al.   Journal of Hematology & Oncology

Hydrogen sulfide modulates chromatin remodeling and inflammatory mediator production in response to endotoxin, but does not play a role in the development of endotoxin tolerance

(2016) Ester C. S. Rios et al.   Journal of Inflammation-London

Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency

(2016) Andrew A. M. Morris et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Hydrogen polysulfide (H2S n ) signaling along with hydrogen sulfide (H2S) and nitric oxide (NO)

(2016) Hideo Kimura   JOURNAL OF NEURAL TRANSMISSION

Effect of Hydrogen Sulfide Donors on Intraocular Pressure in Rabbits

(2016) Ankita Salvi et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Comfortably Numb and Back: Plasma Metabolomics Reveals Biochemical Adaptations in the Hibernating 13-Lined Ground Squirrel

(2016) Angelo D’Alessandro et al.   JOURNAL OF PROTEOME RESEARCH

Hydrogen Sulfide Facilitates Vaginal Lubrication by Activation of Epithelial ATP-Sensitive K + Channels and Cystic Fibrosis Transmembrane Conductance Regulator

(2016) Qing Sun et al.   Journal of Sexual Medicine

Independent Correlation of Serum Homocysteine with Cerebral Microbleeds in Patients with Acute Ischemic Stroke due to Large-Artery Atherosclerosis

(2016) Bian-Rong Wang et al.   Journal of Stroke & Cerebrovascular Diseases

Smelling Sulfur: Copper and Silver Regulate the Response of Human Odorant Receptor OR2T11 to Low-Molecular-Weight Thiols

(2016) Shengju Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Upregulation of spinal NMDA receptors mediates hydrogen sulfide-induced hyperalgesia

(2016) Shuang Zhao et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Hydrogen sulfide donor NaHS induces death of alveolar epithelial L2 cells that is associated with cellular shrinkage, transgelin expression and myosin phosphorylation

(2016) Yusuke Fujii et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Hydrogen Sulfide Induced Erythropoietin Synthesis is Regulated by HIF Proteins

(2016) Jennifer Leigh et al.   JOURNAL OF UROLOGY

Involvement of Hydrogen Sulfide in Endothelium-Derived Relaxing Factor-Mediated Responses in Rat Cerebral Arteries

(2016) Mei Wang et al.   JOURNAL OF VASCULAR RESEARCH

Hydrogen sulfide suppresses endoplasmic reticulum stress-induced endothelial-to-mesenchymal transition through Src pathway

(2016) Ru Ying et al.   LIFE SCIENCES

Design of a Novel Composite H2S-Releasing Hydrogel for Cardiac Tissue Repair

(2016) Arianna Mauretti et al.   MACROMOLECULAR BIOSCIENCE

Hypoxic conditions increases H2S-induced ER stress in A2870 cells

(2016) Lubomira Lencesova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mechanisms Underlying Adaptation to Life in Hydrogen Sulfide–Rich Environments

(2016) Joanna L. Kelley et al.   MOLECULAR BIOLOGY AND EVOLUTION

Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug Approach

(2016) Celia Chao et al.   MOLECULAR MEDICINE

Hydrogen sulfide suppresses angiotensin II-stimulated endothelin-1 generation and subsequent cytotoxicity-induced endoplasmic reticulum stress in endothelial cells via NF-κB

(2016) Heng-Jing Hu et al.   Molecular Medicine Reports

Effects of bamboo salt and its component, hydrogen sulfide, on enhancing immunity

(2016) Na-Rae Kim et al.   Molecular Medicine Reports

Hydrogen sulfide is a novel potential virulence factor ofMycoplasma pneumoniae: characterization of the unusual cysteine desulfurase/desulfhydrase HapE

(2016) Stephanie Großhennig et al.   MOLECULAR MICROBIOLOGY

Expression of 3-Mercaptopyruvate Sulfurtransferase in the Mouse

(2016) Masahiro Tomita et al.   MOLECULES

Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness

(2016) Nicholas M Morton et al.   NATURE MEDICINE

Ischaemic conditioning and reperfusion injury

(2016) Derek J. Hausenloy et al.   Nature Reviews Cardiology

Arecoline Induces Neurotoxicity to PC12 Cells: Involvement in ER Stress and Disturbance of Endogenous H2S Generation

(2016) Jia-Mei Jiang et al.   NEUROCHEMICAL RESEARCH

Endogenous CBS–H2S Pathway Contributes to the Development of CCI-Induced Neuropathic Pain

(2016) Yulong Gui et al.   NEUROCHEMICAL RESEARCH

Calcitriol prevents peripheral RSC96 Schwann neural cells from high glucose & methylglyoxal-induced injury through restoration of CBS/H 2 S expression

(2016) Hui Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Delayed gastric emptying in diabetic rats caused by decreased expression of cystathionine gamma lyase and H2S synthesis:in vitroandin vivostudies

(2016) S. A. Mard et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Slow sulfide donor GYY4137 differentiates NG108-15 neuronal cells through different intracellular transporters than dbcAMP

(2016) J. Kubickova et al.   NEUROSCIENCE

GluN2B-containing NMDA receptors contribute to the beneficial effects of hydrogen sulfide on cognitive and synaptic plasticity deficits in APP/PS1 transgenic mice

(2016) Yuan-Jian Yang et al.   NEUROSCIENCE

Hydrogen sulfide attenuates brain edema in early brain injury after subarachnoid hemorrhage in rats: Possible involvement of MMP-9 induced blood-brain barrier disruption and AQP4 expression

(2016) Shenglong Cao et al.   NEUROSCIENCE LETTERS

Stimulatory effect of CSE-generated H2S on hepatic mitochondrial biogenesis and the underlying mechanisms

(2016) Ashley A. Untereiner et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

High urinary sulfate concentration is associated with reduced risk of renal disease progression in type 2 diabetes

(2016) Joost C. van den Born et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Exogenous hydrogen sulfide exerts proliferation, anti-apoptosis, migration effects and accelerates cell cycle progression in multiple myeloma cells via activating the Akt pathway

(2016) Dong Zheng et al.   ONCOLOGY REPORTS

Exogenous hydrogen sulfide exerts proliferation, anti-apoptosis, angiopoiesis and migration effects via activating HSP90 pathway in EC109 cells

(2016) YIYAN LEI et al.   ONCOLOGY REPORTS

Epithelial Electrolyte Transport Physiology and the Gasotransmitter Hydrogen Sulfide

(2016) Ervice Pouokam et al.   Oxidative Medicine and Cellular Longevity

Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide

(2016) Zongmin Zhou et al.   PHARMACOLOGICAL RESEARCH

Hydrogen sulfide-releasing anti-inflammatory drugs for chemoprevention and treatment of cancer

(2016) Angela Ianaro et al.   PHARMACOLOGICAL RESEARCH

Targeting the transsulfuration-H 2 S pathway by FXR and GPBAR1 ligands in the treatment of portal hypertension

(2016) Stefano Fiorucci et al.   PHARMACOLOGICAL RESEARCH

H 2 S-induced thiol-based redox switches: Biochemistry and functional relevance for inflammatory diseases

(2016) Sebastian Longen et al.   PHARMACOLOGICAL RESEARCH

Regulation and role of endogenously produced hydrogen sulfide in angiogenesis

(2016) Antonia Katsouda et al.   PHARMACOLOGICAL RESEARCH

The novel mitochondria-targeted hydrogen sulfide (H 2 S) donors AP123 and AP39 protect against hyperglycemic injury in microvascular endothelial cells in vitro

(2016) Domokos Gerő et al.   PHARMACOLOGICAL RESEARCH

HMGB1 as biomarker and drug target

(2016) Emilie Venereau et al.   PHARMACOLOGICAL RESEARCH

Hydrogen Sulfide and T-Type Ca2+ Channels in Pain Processing, Neuronal Differentiation and Neuroendocrine Secretion

(2016) Kazuki Fukami et al.   PHARMACOLOGY

The effects of hydrogen sulfide on platelet–leukocyte aggregation and microvascular thrombolysis

(2016) Eberhard Grambow et al.   PLATELETS

Replicative Senescence in Human Fibroblasts Is Delayed by Hydrogen Sulfide in a NAMPT/SIRT1 Dependent Manner

(2016) Reiko Sanokawa-Akakura et al.   PLoS One

Hydrogen Sulfide Delays LPS-Induced Preterm Birth in Mice via Anti-Inflammatory Pathways

(2016) Weina Liu et al.   PLoS One

Delayed Treatment with Sodium Hydrosulfide Improves Regional Blood Flow and Alleviates Cecal Ligation and Puncture (CLP)-Induced Septic Shock

(2016) Akbar Ahmad et al.   SHOCK

AP39, A Mitochondrially Targeted Hydrogen Sulfide Donor, Exerts Protective Effects in Renal Epithelial Cells Subjected to Oxidative Stress in Vitro and in Acute Renal Injury in Vivo

(2016) Akbar Ahmad et al.   SHOCK

Cystathionine metabolic enzymes play a role in the inflammation resolution of human keratinocytes in response to sub-cytotoxic formaldehyde exposure

(2016) Eunyoung Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Sulfide as a Mucus Barrier-Breaker in Inflammatory Bowel Disease?

(2016) Noortje Ijssennagger et al.   TRENDS IN MOLECULAR MEDICINE

Improved tag-switch method reveals that thioredoxin acts as depersulfidase and controls the intracellular levels of protein persulfidation

(2016) Rudolf Wedmann et al.   Chemical Science

Hydrogen Sulfide Recruits Macrophage Migration by Integrin β1-Src-FAK/Pyk2-Rac Pathway in Myocardial Infarction

(2016) Lei Miao et al.   Scientific Reports

Exogenous H2S modulates mitochondrial fusion–fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state

(2016) Aili Sun et al.   Cell and Bioscience

Hydrogen Sulfide Attenuates Tissue Plasminogen Activator-Induced Cerebral Hemorrhage Following Experimental Stroke

(2016) Hui Liu et al.   Translational Stroke Research

Mutations in AML: prognostic and therapeutic implications

(2016) C. D. DiNardo et al.   Hematology-American Society of Hematology Education Program

Independent Correlation of Serum Homocysteine with Cerebral Microbleeds in Patients with Acute Ischemic Stroke due to Large-Artery Atherosclerosis

(2016) Bian-Rong Wang et al.   Journal of Stroke & Cerebrovascular Diseases

Hydrogen sulfide metabolism regulates endothelial solute barrier function

(2016) Shuai Yuan et al.   Redox Biology

Low sulfide levels and a high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) in the long-lived naked mole-rat

(2016) Maja Dziegelewska et al.   Redox Biology

The role of hydrogen sulfide in homocysteine-induced cardiodynamic effects and oxidative stress markers in the isolated rat heart

(2016) M Stojanovic et al.   Physiology International

A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems

(2016) E. Doka et al.   Science Advances

Characterization and Expression of the Lucina pectinata Oxygen and Sulfide Binding Hemoglobin Genes

(2016) Ingrid M. Montes-Rodríguez et al.   PLoS One

Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis

(2016) Ravinder Reddy Gaddam et al.   PLoS One

Role of Cystathionine Gamma-Lyase in Immediate Renal Impairment and Inflammatory Response in Acute Ischemic Kidney Injury

(2016) Lajos Markó et al.   Scientific Reports

Cystathionine-β-Synthase Gene Transfer Into Rostral Ventrolateral Medulla Exacerbates Hypertension via Nitric Oxide in Spontaneously Hypertensive Rats

(2015) Xiao-Cui Duan et al.   AMERICAN JOURNAL OF HYPERTENSION

Inhibition of RhoA-dependent pathway and contraction by endogenous hydrogen sulfide in rabbit gastric smooth muscle cells

(2015) Ancy D. Nalli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Gene transfer of cystathionine β-synthase into RVLM increases hydrogen sulfide-mediated suppression of sympathetic outflow via KATP channel in normotensive rats

(2015) Xiao-cui Duan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids

(2015) Barbara Renga et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The H2S-generating enzymes cystathionine β-synthase and cystathionine γ-lyase play a role in vascular development during normal lung alveolarization

(2015) Alicia Madurga et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Hydrogen sulfide production from subgingival plaque samples

(2015) A. Basic et al.   ANAEROBE

Hydrogen Sulfide Maintains Mitochondrial DNA Replication via Demethylation of TFAM

(2015) Shuangshuang Li et al.   ANTIOXIDANTS & REDOX SIGNALING

The Therapeutic Potential of Cystathionine β-Synthetase/Hydrogen Sulfide Inhibition in Cancer

(2015) Mark R. Hellmich et al.   ANTIOXIDANTS & REDOX SIGNALING

S-Glutathionylation Enhances Human Cystathionine β-Synthase Activity Under Oxidative Stress Conditions

(2015) Wei-Ning Niu et al.   ANTIOXIDANTS & REDOX SIGNALING

Signaling Molecules: Hydrogen Sulfide and Polysulfide

(2015) Hideo Kimura   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide as an Oxygen Sensor

(2015) Kenneth R. Olson   ANTIOXIDANTS & REDOX SIGNALING

Anti-Inflammatory and Cytoprotective Actions of Hydrogen Sulfide: Translation to Therapeutics

(2015) John L. Wallace et al.   ANTIOXIDANTS & REDOX SIGNALING

Antidepressant-like and anxiolytic-like effects of hydrogen sulfide in streptozotocin-induced diabetic rats through inhibition of hippocampal oxidative stress

(2015) Zhuo-Jun Tang et al.   BEHAVIOURAL PHARMACOLOGY

Hydrogen sulfide induces hyperpolarization and decreases the exocytosis of secretory granules of rat GH3 pituitary tumor cells

(2015) Alsu N. Mustafina et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Polysulfide promotes neuroblastoma cell differentiation by accelerating calcium influx

(2015) Shin Koike et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hydrogen sulfide protects against myocardial ischemia and reperfusion injury by activating AMP-activated protein kinase to restore autophagic flux

(2015) Hong Xie et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

H2S-induced S-sulfhydration of pyruvate carboxylase contributes to gluconeogenesis in liver cells

(2015) YoungJun Ju et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Hydrogen sulphide induces HIF-1α and Nrf2 in THP-1 macrophages

(2015) Lilian Lohninger et al.   BIOCHIMIE

Marine natural products as inhibitors of cystathionine beta-synthase activity

(2015) Megan K. Thorson et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The H 2 S-producing enzyme CSE is dispensable for the processing of inflammatory and neuropathic pain

(2015) Katharina M.J. Syhr et al.   BRAIN RESEARCH

Effects of Hydrogen Sulfide on Modulation of Theta–Gamma Coupling in Hippocampus in Vascular Dementia Rats

(2015) Xiaxia Xu et al.   BRAIN TOPOGRAPHY

Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats

(2015) P M Snijder et al.   BRITISH JOURNAL OF PHARMACOLOGY

Unravelling the theories of pre-eclampsia: are the protective pathways the new paradigm?

(2015) Asif Ahmed et al.   BRITISH JOURNAL OF PHARMACOLOGY

(Potentially) traumatic events

(2015) Ruth Reed   BRITISH JOURNAL OF PSYCHIATRY

A possible molecular mechanism of hearing loss during cerebral ischemia in mice

(2015) Pradip Kumar Kamat et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway

(2015) Sofia-Iris Bibli et al.   CARDIOVASCULAR RESEARCH

Cystathionine γ-lyase regulates arteriogenesis through NO-dependent monocyte recruitment

(2015) Gopi K. Kolluru et al.   CARDIOVASCULAR RESEARCH

A Novel Hydrogen Sulfide Prodrug, SG1002, Promotes Hydrogen Sulfide and Nitric Oxide Bioavailability in Heart Failure Patients

(2015) David J. Polhemus et al.   Cardiovascular Therapeutics

Endogenous Hydrogen Sulfide Production Is Essential for Dietary Restriction Benefits

(2015) Christopher Hine et al.   CELL

Effects of Diurnal Variation of Gut Microbes and High-Fat Feeding on Host Circadian Clock Function and Metabolism

(2015) Vanessa Leone et al.   Cell Host & Microbe

The endoplasmic reticulum: structure, function and response to cellular signaling

(2015) Dianne S. Schwarz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Reaction between a haemoglobin model compound and hydrosulphide in aqueous solution

(2015) Kenji Watanabe et al.   CHEMICAL COMMUNICATIONS

Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems

(2015) Vivian S. Lin et al.   CHEMICAL SOCIETY REVIEWS

Enzymatic diagnosis of homocystinuria by determination of cystathionine-ß-synthase activity in plasma using LC-MS/MS

(2015) P. Alcaide et al.   CLINICA CHIMICA ACTA

Cystathionine  -synthase-derived hydrogen sulfide is involved in human malignant hyperthermia

(2015) V. Vellecco et al.   CLINICAL SCIENCE

Effects of infusion of human methemoglobin solution following hydrogen sulfide poisoning

(2015) B. Chenuel et al.   CLINICAL TOXICOLOGY

The effect of a hydrogen sulfide releasing molecule (Na2S) on the cold storage of livers from cardiac dead donor rats. A study in an ex vivo model

(2015) Cecilia Lucía Balaban et al.   CRYOBIOLOGY

A new approach for epoxidation of fatty acids by a paired electrosynthesis

(2015) Wanjie Li et al.   ELECTROCHEMISTRY COMMUNICATIONS

MiR-22/Sp-1 Links Estrogens With the Up-Regulation of Cystathionine γ-Lyase in Myocardium, Which Contributes to Estrogenic Cardioprotection Against Oxidative Stress

(2015) Long Wang et al.   ENDOCRINOLOGY

The protective effects of endogenous hydrogen sulfide modulator, S-propargyl-cysteine, on high glucose-induced apoptosis in cardiomyocytes: A novel mechanism mediated by the activation of Nrf2

(2015) Hebei Yang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Calorie restriction and methionine restriction in control of endogenous hydrogen sulfide production by the transsulfuration pathway

(2015) Christopher Hine et al.   EXPERIMENTAL GERONTOLOGY

Sodium Hydrosulfide Exerts a Transitional Attenuating Effect on Spermatozoa Migration in Vitro

(2015) Bogdan Wiliński et al.   FOLIA BIOLOGICA-KRAKOW

Insights into the mechanism of the reaction between hydrogen sulfide and peroxynitrite

(2015) Ernesto Cuevasanta et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hydrogen Sulfide Inhibits Human Platelet Aggregation In Vitro in Part by Interfering Gap Junction Channels: Effects of ACS14, a Hydrogen Sulfide-releasing Aspirin

(2015) Lin Gao et al.   Heart Lung and Circulation

DNMT1-associated long non-coding RNAs regulate global gene expression and DNA methylation in colon cancer

(2015) Callie R. Merry et al.   HUMAN MOLECULAR GENETICS

Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis

(2015) Ruili Yang et al.   IMMUNITY

Manipulation of regulatory T cells and antigen-specific cytotoxic T lymphocyte-based tumour immunotherapy

(2015) Shirin Karimi et al.   IMMUNOLOGY

Epithelial sodium channel is involved in H2S-induced acute pulmonary edema

(2015) Lei Jiang et al.   INHALATION TOXICOLOGY

Hydrogen sulfide attenuates cytokine production through the modulation of chromatin remodeling

(2015) ESTER C.S. RIOS et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter

(2015) Jiao-Jiao Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exogenous hydrogen sulfide exerts proliferation/anti-apoptosis/angiogenesis/migration effects via amplifying the activation of NF-κB pathway in PLC/PRF/5 hepatoma cells

(2015) YULAN ZHEN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Transcriptional Regulation of Cystathionine-γ-Lyase in Endothelial Cells by NADPH Oxidase 4-Dependent Signaling

(2015) Rajesh K. Mistry et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency

(2015) Francesco Grassi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Hydrogen Sulfide Inhalation Decreases Early Blood—Brain Barrier Permeability and Brain Edema Induced by Cardiac Arrest and Resuscitation

(2015) Yingjie Geng et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Comparative exploration of hydrogen sulfide and water transmembrane free energy surfaces via orthogonal space tempering free energy sampling

(2015) Chao Lv et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

MD-2 is required for disulfide HMGB1–dependent TLR4 signaling

(2015) Huan Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hyperhomocysteinemia abrogates fasting-induced cardioprotection against ischemia/reperfusion by limiting bioavailability of hydrogen sulfide anions

(2015) Shintaro Nakano et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Erythrocytic Hydrogen Sulfide Production Is Increased in Children with Vasovagal Syncope

(2015) Jinyan Yang et al.   JOURNAL OF PEDIATRICS

Physiologic Levels of Endogenous Hydrogen Sulfide Maintain the Proliferation and Differentiation Capacity of Periodontal Ligament Stem Cells

(2015) Yingying Su et al.   JOURNAL OF PERIODONTOLOGY

Hydrogen Sulfide Inhibits Amyloid Formation

(2015) Manuel F. Rosario-Alomar et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Hypoxic pulmonary vasoconstriction in isolated rat pulmonary arteries is not inhibited by antagonists of H2S-synthesizing pathways

(2015) Jesus Prieto-Lloret et al.   JOURNAL OF PHYSIOLOGY-LONDON

Hydrogen sulfide improves resuscitation via non-hibernatory mechanisms in a porcine shock model

(2015) Steven A. Satterly et al.   JOURNAL OF SURGICAL RESEARCH

Protective effects of hydrogen sulfide anions against acetaminophen-induced hepatotoxicity in mice

(2015) Isao Ishii et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Hydrogen Sulfide Treatment Mitigates Renal Allograft Ischemia-Reperfusion Injury during Cold Storage and Improves Early Transplant Kidney Function and Survival Following Allogeneic Renal Transplantation

(2015) Ian Lobb et al.   JOURNAL OF UROLOGY

Hydrogen sulfide decreases the plasma lipid peroxidation induced by homocysteine and its thiolactone

(2015) Beata Olas et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Persulfides: current knowledge and challenges in chemistry and chemical biology

(2015) Chung-Min Park et al.   Molecular BioSystems

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(2015) Attila Brunyanszki et al.   MOLECULAR MEDICINE

CSE/H2S system protects mesenchymal stem cells from hypoxia and serum deprivation-induced apoptosis via mitochondrial injury, endoplasmic reticulum stress and PI3K/Akt activation pathways

(2015) ZENG GUO et al.   Molecular Medicine Reports

Hydrogen Sulfide Ameliorates Homocysteine-Induced Alzheimer’s Disease-Like Pathology, Blood–Brain Barrier Disruption, and Synaptic Disorder

(2015) Pradip K. Kamat et al.   MOLECULAR NEUROBIOLOGY

Hydrogen Sulfide Ameliorates Early Brain Injury Following Subarachnoid Hemorrhage in Rats

(2015) Yonghua Cui et al.   MOLECULAR NEUROBIOLOGY

Gaseous Mediators Nitric Oxide and Hydrogen Sulfide in the Mechanism of Gastrointestinal Integrity, Protection and Ulcer Healing

(2015) Marcin Magierowski et al.   MOLECULES

Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways

(2015) Tatiana V Mishanina et al.   Nature Chemical Biology

Gasotransmitters in cancer: from pathophysiology to experimental therapy

(2015) Csaba Szabo   NATURE REVIEWS DRUG DISCOVERY

Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter

(2015) John L. Wallace et al.   NATURE REVIEWS DRUG DISCOVERY

Hydrogen sulfide accelerates the recovery of kidney tubules after renal ischemia/reperfusion injury

(2015) Sang Jun Han et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Pharmacological Actions of Hydrogen Sulfide Donors on Sympathetic Neurotransmission in the Bovine Anterior Uvea, In Vitro

(2015) Ankita Salvi et al.   NEUROCHEMICAL RESEARCH

Reduction of hydrogen sulfide synthesis enzymes in the esophagus of patients with achalasia: effect of hydrogen sulfide in achalasia

(2015) L. Zhang et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Role of hydrogen sulfide within the dorsal motor nucleus of the vagus in the control of gastric function in rats

(2015) H.-Z. Sun et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Mechanisms of hydrogen sulfide (H2S) action on synaptic transmission at the mouse neuromuscular junction

(2015) E. Gerasimova et al.   NEUROSCIENCE

Neuronal regulation of expression of hydrogen sulfide-producing enzyme cystathionine β-synthase in rat spinal cord astrocytes

(2015) Ryo Miyamoto et al.   NEUROSCIENCE RESEARCH

Tweet like it's 2099

(2015)   NEW SCIENTIST

Inhaled hydrogen sulfide prevents neuropathic pain after peripheral nerve injury in mice

(2015) Kotaro Kida et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Different patterns of H2S/NO activity and cross-talk in the control of the coronary vascular bed under normotensive or hypertensive conditions

(2015) L. Testai et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Mitochondria-targeted hydrogen sulfide donor AP39 improves neurological outcomes after cardiac arrest in mice

(2015) Kohei Ikeda et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Role of cGMP in hydrogen sulfide signaling

(2015) Sofia-Iris Bibli et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Effects of AP39, a novel triphenylphosphonium derivatised anethole dithiolethione hydrogen sulfide donor, on rat haemodynamic parameters and chloride and calcium Cav3 and RyR2 channels

(2015) Lenka Tomasova et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydrogen sulfide is involved in dexamethasone-induced hypertension in rat

(2015) Roberta d'Emmanuele di Villa Bianca et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Protective effect of hydrogen sulfide on pancreatic beta-cells

(2015) Mitsuhiro Okamoto et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Down-regulated CBS/H2S pathway is involved in high-salt-induced hypertension in Dahl rats

(2015) Pan Huang et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

H2S-releasing drugs: Anti-inflammatory, cytoprotective and chemopreventative potential

(2015) Burcu Gemici et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Impact of Carbon Monoxide/Heme Oxygenase on Hydrogen Sulfide/Cystathionine-γ-lyase Pathway in the Pathogenesis of Allergic Rhinitis in Guinea Pigs

(2015) Shaoqing Yu et al.   OTOLARYNGOLOGY-HEAD AND NECK SURGERY

Cardiac H2S Generation Is Reduced in Ageing Diabetic Mice

(2015) Sheng Jin et al.   Oxidative Medicine and Cellular Longevity

Elevated Inducible Nitric Oxide Levels and Decreased Hydrogen Sulfide Levels Can Predict the Risk of Coronary Artery Ectasia in Kawasaki Disease

(2015) Ruixia Song et al.   PEDIATRIC CARDIOLOGY

Plasma H2 S predicts coronary artery lesions in children with Kawasaki disease

(2015) Yan Sun et al.   PEDIATRICS INTERNATIONAL

Hydrogen sulfide inhalation ameliorates allergen induced airway hypereactivity by modulating mast cell activation

(2015) Fiorentina Roviezzo et al.   PHARMACOLOGICAL RESEARCH

Investigation of Hydrogen Sulfide Exposure and Lung Function, Asthma and Chronic Obstructive Pulmonary Disease in a Geothermal Area of New Zealand

(2015) Michael N. Bates et al.   PLoS One

Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease

(2015) Tommy Pacana et al.   PLoS One

Endogenous Prostaglandins and Afferent Sensory Nerves in Gastroprotective Effect of Hydrogen Sulfide against Stress-Induced Gastric Lesions

(2015) Marcin Magierowski et al.   PLoS One

Hydrogen sulfide activates the carotid body chemoreceptors in cat, rabbit and rat ex vivo preparations

(2015) Yingfu Jiao et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Hydrogen sulfide suppresses transforming growth factor-β1-induced differentiation of human cardiac fibroblasts into myofibroblasts

(2015) YouEn Zhang et al.   Science China-Life Sciences

H2S induces vasoconstriction of rat cerebral arteries via cAMP/adenylyl cyclase pathway

(2015) Sen Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hydrogen sulfide-induced enhancement of gastric fundus smooth muscle tone is mediated by voltage-dependent potassium and calcium channels in mice

(2015) Xiang-Min Meng   WORLD JOURNAL OF GASTROENTEROLOGY

Effect of hydrogen sulfide on inflammatory cytokines in acute myocardial ischemia injury in rats

(2015) FANG LIU et al.   Experimental and Therapeutic Medicine

Detection of cancer through exhaled breath: a systematic review

(2015) Agne Krilaviciute et al.   Oncotarget

Metabolic changes of H2S in smokers and patients of COPD which might involve in inflammation, oxidative stress and steroid sensitivity

(2015) Yun Sun et al.   Scientific Reports

Hydrogen sulfide-induced itch requires activation of Cav3.2 T-type calcium channel in mice

(2015) Xue-Long Wang et al.   Scientific Reports

H2S, a novel gasotransmitter, involves in gastric accommodation

(2015) Ailin Xiao et al.   Scientific Reports

Roles of Sulfur Metabolism and Rhodanese in Detoxification and Anti-Oxidative Stress Functions in the Liver: Responses to Radiation Exposure

(2015) Tetsuo Nakajima   MEDICAL SCIENCE MONITOR

Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap

(2015) H. Jiang et al.   Biology Open

NOSH-sulindac (AVT-18A) is a novel nitric oxide- and hydrogen sulfide-releasing hybrid that is gastrointestinal safe and has potent anti-inflammatory, analgesic, antipyretic, anti-platelet, and anti-cancer properties

(2015) Khosrow Kashfi et al.   Redox Biology

Deficiency of cystathionine gamma-lyase and hepatic cholesterol accumulation during mouse fatty liver development

(2015) Sarathi Mani et al.   Science Bulletin

Subject Index

(2015) &NA;   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

Pain in the network of genetic and epigenetic control

(2015) Jörn Lötsch et al.   Molecular Pain

Hydrogen Sulfide Donor Protects Porcine Oocytes against Aging and Improves the Developmental Potential of Aged Porcine Oocytes

(2015) Tereza Krejcova et al.   PLoS One

Hydrogen Sulfide Promotes Adipogenesis in 3T3L1 Cells

(2015) Chin-Yi Tsai et al.   PLoS One

Use of the Analysis of the Volatile Faecal Metabolome in Screening for Colorectal Cancer

(2015) Claire A Batty et al.   PLoS One

Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1

(2015) Barbara Renga et al.   PLoS One

Differential Cytotoxicity of Acetaminophen in Mouse Macrophage J774.2 and Human Hepatoma HepG2 Cells: Protection by Diallyl Sulfide

(2015) Haider Raza et al.   PLoS One

Hydrogen sulfide inhibits homocysteine-induced endoplasmic reticulum stress and neuronal apoptosis in rat hippocampus via upregulation of the BDNF-TrkB pathway

(2014) Hai-jun Wei et al.   ACTA PHARMACOLOGICA SINICA

Central hydrogen sulphide mediates ventilatory responses to hypercapnia in adult conscious rats

(2014) G. S. F. da Silva et al.   Acta Physiologica

Correlation between the cystathionine-r-lyase (CES) and the severity of peptic ulcer disease

(2014) Xiong Chen et al.   African Health Sciences

Alterations of Retinal Vasculature in Cystathionine–β-Synthase Heterozygous Mice

(2014) Amany Tawfik et al.   AMERICAN JOURNAL OF PATHOLOGY

Endogenous Production of Hydrogen Sulfide in Human Sinus Mucosa and its Expression Levels are Altered in Patients with Chronic Rhinosinusitis with and without Nasal Polyps

(2014) Jae Woong Hwang et al.   American Journal of Rhinology & Allergy

Sodium Thiosulfate Attenuates Acute Lung Injury in Mice

(2014) Masahiro Sakaguchi et al.   ANESTHESIOLOGY

CBS and CSE Are Critical for Maintenance of Mitochondrial Function and Glucocorticoid Production in Adrenal Cortex

(2014) Chang-Nan Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

CaMKKβ-Dependent Activation of AMP-Activated Protein Kinase Is Critical to Suppressive Effects of Hydrogen Sulfide on Neuroinflammation

(2014) Xiaomei Zhou et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen sulfide synergistically upregulates Porphyromonas gingivalis lipopolysaccharide-induced expression of IL-6 and IL-8 via NF-κB signalling in periodontal fibroblasts

(2014) Xiao-Pei Chi et al.   ARCHIVES OF ORAL BIOLOGY

Upcoming Meetings

(2014)   ARTIFICIAL ORGANS

Disturbance of endogenous hydrogen sulfide generation and endoplasmic reticulum stress in hippocampus are involved in homocysteine-induced defect in learning and memory of rats

(2014) Man-Hong Li et al.   BEHAVIOURAL BRAIN RESEARCH

Downregulation of cystathionine β-synthase/hydrogen sulfide contributes to rotenone-induced microglia polarization toward M1 type

(2014) Chenchen Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endogenous and exogenous hydrogen sulfide facilitates T-type calcium channel currents in Cav3.2-expressing HEK293 cells

(2014) Fumiko Sekiguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The cystathionine γ-lyase/hydrogen sulfide system maintains cellular glutathione status

(2014) Zheng-Wei Lee et al.   BIOCHEMICAL JOURNAL

Meetings Calendar

(2014)   BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION

Correlation of Lower Concentrations of Hydrogen Sulfide with Atherosclerosis in Chronic Hemodialysis Patients with Diabetic Nephropathy

(2014) Han Li et al.   BLOOD PURIFICATION

Check the fit accuracy of prosthetics

(2014)   BRITISH DENTAL JOURNAL

Crucial role of androgen receptor in vascular H2S biosynthesis induced by testosterone

(2014) V Brancaleone et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pharmacological tools for hydrogen sulphide research: a brief, introductory guide for beginners

(2014) Andreas Papapetropoulos et al.   BRITISH JOURNAL OF PHARMACOLOGY

Gas what: NO is not the only answer to sexual function

(2014) G Yetik-Anacak et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition

(2014) Mariarosaria Bucci et al.   CARDIOVASCULAR RESEARCH

Hydrogen sulphide triggers VEGF-induced intracellular Ca2+ signals in human endothelial cells but not in their immature progenitors

(2014) Duilio Michele Potenza et al.   CELL CALCIUM

Neurodegeneration in Huntington's disease involves loss of cystathionine γ-lyase

(2014) Bindu D Paul et al.   CELL CYCLE

Hydrogen Sulfide Maintains Mesenchymal Stem Cell Function and Bone Homeostasis via Regulation of Ca2+ Channel Sulfhydration

(2014) Yi Liu et al.   Cell Stem Cell

Role of Calcium Channels in the Protective Effect of Hydrogen Sulfide in Rat Cardiomyoblasts

(2014) Daniele Avanzato et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Fluorescent probes for hydrogen sulfide detection and bioimaging

(2014) Fabiao Yu et al.   CHEMICAL COMMUNICATIONS

The possible role of hydrogen sulfide as a modulator of hemostatic parameters of plasma

(2014) Beata Olas et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Emergence of Hydrogen Sulfide as an Endogenous Gaseous Signaling Molecule in Cardiovascular Disease

(2014) David J. Polhemus et al.   CIRCULATION RESEARCH

The vitamin B12 analog cobinamide is an effective hydrogen sulfide antidote in a lethal rabbit model

(2014) M. Brenner et al.   CLINICAL TOXICOLOGY

Aggravation of Seizure-like Events by Hydrogen Sulfide: Involvement of Multiple Targets that Control Neuronal Excitability

(2014) Yi Luo et al.   CNS Neuroscience & Therapeutics

Endothelial Dysfunction: The Link Between Homocysteine and Hydrogen Sulfide

(2014) Sathnur Pushpakumar et al.   CURRENT MEDICINAL CHEMISTRY

Hydrogen Sulfide and Endothelial Dysfunction: Relationship with Nitric Oxide

(2014) Zaid Altaany et al.   CURRENT MEDICINAL CHEMISTRY

Bacterial gasotransmitters: an innate defense against antibiotics

(2014) Lyly Luhachack et al.   CURRENT OPINION IN MICROBIOLOGY

Mitochondrial Biogenesis: Regulation By Endogenous Gases During Inflammation and Organ Stress

(2014) Hagir Suliman et al.   CURRENT PHARMACEUTICAL DESIGN

The immunomodulation of inducible hydrogen sulfide in Pacific oyster Crassostrea gigas

(2014) Zhibin Sun et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Hydrogen Sulfide Improves Wound Healing via Restoration of Endothelial Progenitor Cell Functions and Activation of Angiopoietin-1 in Type 2 Diabetes

(2014) Fang Liu et al.   DIABETES

Kinetics and Mechanism of the Reaction of Hydrogen Sulfide with Diaquacobinamide in Aqueous Solution

(2014) Denis S. Salnikov et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Cellular mechanism underlying hydrogen sulfide induced mouse tracheal smooth muscle relaxation: Role of BKCa

(2014) Jiehong Huang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of hydrogen sulfide in the formalin-induced orofacial pain in rats

(2014) Alberto F. Donatti et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hydrogen sulfide protected gastric epithelial cell from ischemia/reperfusion injury by Keap1 s-sulfhydration, MAPK dependent anti-apoptosis and NF-κB dependent anti-inflammation pathway

(2014) Cheng Guo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Impact of theophylline/corticosteroid combination therapy on sputum hydrogen sulfide levels in patients with COPD

(2014) P. A. Kirkham et al.   EUROPEAN RESPIRATORY JOURNAL

Hydrogen sulfide inhibits Cav3.2 T-type Ca2+ channels

(2014) Jacobo Elies et al.   FASEB JOURNAL

Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: Implications of their possible biological activity and utility

(2014) Katsuhiko Ono et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hydrogen sulfide and nitric oxide metabolites in the blood of free-ranging brown bears and their potential roles in hibernation

(2014) Inge G. Revsbech et al.   FREE RADICAL BIOLOGY AND MEDICINE

Carbon Monoxide, Hydrogen Sulfide, and Nitric Oxide as Signaling Molecules in the Gastrointestinal Tract

(2014) Gianrico Farrugia et al.   GASTROENTEROLOGY

Hydrogen sulfide treatment reduces blood pressure and oxidative stress in angiotensin II-induced hypertensive mice

(2014) Mohammad R Al-Magableh et al.   HYPERTENSION RESEARCH

Hydrogen sulphide increases hepatic differentiation of human tooth pulp stem cells compared with human bone marrow stem cells

(2014) M. Okada et al.   INTERNATIONAL ENDODONTIC JOURNAL

GYY4137, a hydrogen sulfide (H2S) donor, shows potent anti-hepatocellular carcinoma activity through blocking the STAT3 pathway

(2014) SEN LU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Hydrogen Sulfide Represses Androgen Receptor Transactivation by Targeting at the Second Zinc Finger Module

(2014) Kexin Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization and Interaction Studies of Two Isoforms of the Dual Localized 3-Mercaptopyruvate Sulfurtransferase TUM1 from Humans

(2014) Benjamin Fräsdorf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decreased Cystathionine-γ-lyase (CSE) Activity in Livers of Type 1 Diabetic Rats and Peripheral Blood Mononuclear Cells (PBMC) of Type 1 Diabetic Patients

(2014) Prasenjit Manna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inter-domain Communication of Human Cystathionine β-Synthase

(2014) Thomas J. McCorvie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen Sulfide Alleviates Diabetic Nephropathy in a Streptozotocin-induced Diabetic Rat Model

(2014) Xiang Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibitory Effect of Hydrogen Sulfide on Platelet Aggregation and the Underlying Mechanisms

(2014) Lingling Zhong et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Hydrogen Sulfide Epigenetically Attenuates Homocysteine-Induced Mitochondrial Toxicity Mediated Through NMDA Receptor in Mouse Brain Endothelial (bEnd3) Cells

(2014) Pradip K. Kamat et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Role of MicroRNA29b in Blood–Brain Barrier Dysfunction during Hyperhomocysteinemia: An Epigenetic Mechanism

(2014) Anuradha Kalani et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Hydrogen Sulfide Augments Neutrophil Migration through Enhancement of Adhesion Molecule Expression and Prevention of CXCR2 Internalization: Role of ATP-Sensitive Potassium Channels

(2014) D. Dal-Secco et al.   JOURNAL OF IMMUNOLOGY

H2S Increases Survival during Sepsis: Protective Effect of CHOP Inhibition

(2014) M. Ferlito et al.   JOURNAL OF IMMUNOLOGY

Hydrogen sulfide is essential for Schwann cell responses to peripheral nerve injury

(2014) Byung Sun Park et al.   JOURNAL OF NEUROCHEMISTRY

Hydrogen sulfide protects blood-brain barrier integrity following cerebral ischemia

(2014) Yali Wang et al.   JOURNAL OF NEUROCHEMISTRY

Roles of Cav3.2 and TRPA1 channels targeted by hydrogen sulfide in pancreatic nociceptive processing in mice with or without acute pancreatitis

(2014) Yuka Terada et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Hydrogen sulfide treatment induces angiogenesis after cerebral ischemia

(2014) Hyunduk Jang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Subsets of regulatory T cells and their roles in allergy

(2014) Huiyun Zhang et al.   Journal of Translational Medicine

H2S preconditioning of human adipose tissue-derived stem cells increases their efficacy in an in vitro model of cell therapy for simulated ischemia

(2014) E. Dongó et al.   LIFE SCIENCES

Hydrogen sulfide delays nicotinamide-induced premature senescence via upregulation of SIRT1 in human umbilical vein endothelial cells

(2014) Meihua Zheng et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Cytokine-Induced GAPDH Sulfhydration Affects PSD95 Degradation and Memory

(2014) Sajad Mir et al.   MOLECULAR CELL

Hydrogen sulfide (H2S)/cystathionine γ-lyase (CSE) pathway contributes to the proliferation of hepatoma cells

(2014) Yan Pan et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington’s disease

(2014) Bindu D. Paul et al.   NATURE

Hydrogen sulfide improves spatial memory impairment and decreases production of Aβ in APP/PS1 transgenic mice

(2014) Xuan-li He et al.   NEUROCHEMISTRY INTERNATIONAL

Exogenous H2S enhances mice gastric smooth muscle tension through S-sulfhydration of KV4.3, mediating the inhibition of the voltage-dependent potassium current

(2014) D.-H. Liu et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Hippocampal cystathionine beta synthase in young and aged mice

(2014) J.J. Bruintjes et al.   NEUROSCIENCE LETTERS

Controversies and conundrums in hydrogen sulfide biology

(2014) Kenneth R. Olson et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydrogen sulfide and nitric oxide interactions in inflammation

(2014) Maria Letizia Lo Faro et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Working with “H2S”: Facts and apparent artifacts

(2014) Rudolf Wedmann et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydrogen sulfide and the liver

(2014) Sarathi Mani et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Sodium thiosulfate attenuates angiotensin II-induced hypertension, proteinuria and renal damage11These authors contributed equally to this manuscript.

(2014) Pauline M. Snijder et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro

(2014) Bartosz Szczesny et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydrogen sulfide accelerates cell cycle progression in oral squamous cell carcinoma cell lines

(2014) Z Ma et al.   ORAL DISEASES

Hydrogen sulfide impairs shear stress-induced vasodilation in mouse coronary arteries

(2014) Qiang Chai et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Statins upregulate cystathionine γ-lyase transcription and H2S generation via activating Akt signaling in macrophage

(2014) Yuan Xu et al.   PHARMACOLOGICAL RESEARCH

Role of the cystathionineγlyase/hydrogen sulfide pathway in human melanoma progression

(2014) Elisabetta Panza et al.   Pigment Cell & Melanoma Research

Hydrogen sulfide and cell signaling: Team player or referee?

(2014) J.T. Hancock et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Nitrite Reductase Activity and Inhibition of H2S Biogenesis by Human Cystathionine ß-Synthase

(2014) Carmen Gherasim et al.   PLoS One

Actions of Hydrogen Sulfide on Sodium Transport Processes across Native Distal Lung Epithelia (Xenopus laevis)

(2014) Alexandra Erb et al.   PLoS One

Funding Infectious Disease Research: A Systematic Analysis of UK Research Investments by Funders 1997–2010

(2014) Joseph R. Fitchett et al.   PLoS One

Genetic Targets of Hydrogen Sulfide in Ventilator-Induced Lung Injury – A Microarray Study

(2014) Sashko Spassov et al.   PLoS One

Anti-Atherogenic Effect of Hydrogen Sulfide by Over-Expression of Cystathionine Gamma-Lyase (CSE) Gene

(2014) Sau Ha Cheung et al.   PLoS One

Inherent variations in CO-H2S-mediated carotid body O2 sensing mediate hypertension and pulmonary edema

(2014) Y.-J. Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent

(2014) A. L. King et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxygen-related chemoreceptor drive to breathe during H2S infusion

(2014) Philippe Haouzi et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Correlation between levels of exhaled hydrogen sulfide and airway inflammatory phenotype in patients with chronic persistent asthma

(2014) Jing Zhang et al.   RESPIROLOGY

ELEVATED HYDROGEN SULFIDE LEVELS IN VITREOUS BODY AND PLASMA IN PATIENTS WITH PROLIFERATIVE DIABETIC RETINOPATHY

(2014) Ruijin Ran et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Hydrogen sulfide augments survival signals in warm ischemia and reperfusion of the mouse liver

(2014) Shingo Shimada et al.   SURGERY TODAY

Sputum-to-serum hydrogen sulfide ratio in COPD

(2014) Junpei Saito et al.   THORAX

Sulfur inhibits the growth of androgen-independent prostate cancer in vivo

(2014) FEI DUAN et al.   Oncology Letters

Dysregulation of hydrogen sulphide metabolism impairs oviductal transport of embryos

(2014) Nannan Ning et al.   Nature Communications

The economics of abiraterone acetate for castration-resistant prostate cancer

(2014) Athanasios Dellis et al.   Expert Review of Pharmacoeconomics & Outcomes Research

Antisecretory Effect of Hydrogen Sulfide on Gastric Acid Secretion and the Involvement of Nitric Oxide

(2014) Seyyed Ali Mard et al.   Biomed Research International

Sulphide signalling potentiates apoptosis through the up-regulation of IP3receptor types 1 and 2

(2013) L. Lencesova et al.   Acta Physiologica

The Inhibitory Role of Hydrogen Sulfide in Airway Hyperresponsiveness and Inflammation in a Mouse Model of Asthma

(2013) Gensheng Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Transport of H2S and HS− across the human red blood cell membrane: rapid H2S diffusion and AE1-mediated Cl−/HS− exchange

(2013) Michael L. Jennings   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hydrogen sulfide deficiency and diabetic renal remodeling: role of matrix metalloproteinase-9

(2013) Sourav Kundu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Hydrogen sulfide-based therapeutics and gastrointestinal diseases: translating physiology to treatments

(2013) Melissa V. Chan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Hydrogen sulfide modulates sinusoidal constriction and contributes to hepatic micorcirculatory dysfunction during endotoxemia

(2013) Eric J. Norris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The effect of CSE gene deletion in caerulein-induced acute pancreatitis in the mouse

(2013) Abel D. Ang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Hydrogen sulfide dilates rat mesenteric arteries by activating endothelial large-conductance Ca2+-activated K+ channels and smooth muscle Ca2+ sparks

(2013) Olan Jackson-Weaver et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

H2S concentrations in the arterial blood during H2S administration in relation to its toxicity and effects on breathing

(2013) Candice M. Klingerman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Hydrogen sulfide induces hypersensitivity of rat capsaicin-sensitive lung vagal neurons: role of TRPA1 receptors

(2013) Chun-Chun Hsu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Microplate-Based Colorimetric Detection of Free Hydrogen Sulfide

(2013) Artur P. Jarosz et al.   ANALYTICAL CHEMISTRY

Hydrogen Sulfide Treatment Promotes Glucose Uptake by Increasing Insulin Receptor Sensitivity and Ameliorates Kidney Lesions in Type 2 Diabetes

(2013) Rong Xue et al.   ANTIOXIDANTS & REDOX SIGNALING

H2S Is an Endothelium-Derived Hyperpolarizing Factor

(2013) Guanghua Tang et al.   ANTIOXIDANTS & REDOX SIGNALING

Polysulfides Link H2S to Protein Thiol Oxidation

(2013) Romy Greiner et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxygen Sensing by the Carotid Body: Is It All Just Rotten Eggs?

(2013) Paul J. Kemp et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide Is an Endogenous Regulator of Aging in Caenorhabditis elegans

(2013) Bedoor Qabazard et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Modulation of HMGB1-Related Signaling

(2013) Christina Janko et al.   ANTIOXIDANTS & REDOX SIGNALING

Production and Physiological Effects of Hydrogen Sulfide

(2013) Hideo Kimura   ANTIOXIDANTS & REDOX SIGNALING

Inhibition of hydrogen sulfide production by gene silencing attenuates inflammatory activity of LPS-activated RAW264.7 cells

(2013) Alireza Badiei et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Effect of hydrogen sulphide on the expression of osteoprotegerin and receptor activator of NF-κB ligand in human periodontal ligament cells induced by tension-force stimulation

(2013) Chongshan Liao et al.   ARCHIVES OF ORAL BIOLOGY

Cystathionine γ-lyase Accelerates Osteoclast Differentiation

(2013) Takahiro Itou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Sulfur dioxide upregulates the inhibited endogenous hydrogen sulfide pathway in rats with pulmonary hypertension induced by high pulmonary blood flow

(2013) Liman Luo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of Cystathionine γ-Lyase in Mammalian Cells by Hypoxia

(2013) Maoxian Wang et al.   BIOCHEMICAL GENETICS

Hypoxia-inducible factors regulate human and rat cystathionine β-synthase gene expression

(2013) Naoharu Takano et al.   BIOCHEMICAL JOURNAL

Sulfide inhibition of and metabolism by cytochromecoxidase

(2013) Peter Nicholls et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Chemical aspects of hydrogen sulfide measurements in physiological samples

(2013) Péter Nagy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Brg1-dependent epigenetic control of vascular smooth muscle cell proliferation by hydrogen sulfide

(2013) Li Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Inhibition by Hydrogen Sulfide of Rabbit Platelet Aggregation and Calcium Mobilization

(2013) Hiroyuki Nishikawa et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Rhodamine–propargylic esters for detection of mitochondrial hydrogen sulfide in living cells

(2013) Xi Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

KATP channels of parafacial respiratory group (pFRG) neurons are involved in H2S-mediated central inhibition of respiratory rhythm in medullary slices of neonatal rats

(2013) Li Chen et al.   BRAIN RESEARCH

KV7 channels are involved in hypoxia-induced vasodilatation of porcine coronary arteries

(2013) E R Hedegaard et al.   BRITISH JOURNAL OF PHARMACOLOGY

Treatment with hydrogen sulfide alleviates streptozotocin-induced diabetic retinopathy in rats

(2013) Yan-Fang Si et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effects of hydrogen sulphide on motility patterns in the rat colon

(2013) V Gil et al.   BRITISH JOURNAL OF PHARMACOLOGY

Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE)

(2013) Antonia Asimakopoulou et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects

(2013) Katalin Módis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms

(2013) Csaba Szabo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Storage Stability of Diffusive Samplers and Application to Real Air Samples

(2013) Tomomi YAMADA et al.   BUNSEKI KAGAKU

Modulation of arginine and asymmetric dimethylarginine concentrations in liver and plasma by exogenous hydrogen sulfide in LPS-induced endotoxemia

(2013) Seldag Bekpinar et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

High-fat diet stimulates hepatic cystathionine β-synthase and cystathionine γ-lyase expression

(2013) Sun-Young Hwang et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Hydrogen Sulfide Inhibits Abnormal Proliferation of Lymphocytes via AKT/GSK3� Signal Pathway in Systemic Lupus Erythematosus Patients

(2013) Yanfang Han et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Dysregulation of cystathionine γ-lyase (CSE)/hydrogen sulfide pathway contributes to ox-LDL-induced inflammation in macrophage

(2013) Xian-Hui Wang et al.   CELLULAR SIGNALLING

Dysregulation of Hydrogen Sulfide Producing Enzyme Cystathionine γ-lyase Contributes to Maternal Hypertension and Placental Abnormalities in Preeclampsia

(2013) Keqing Wang et al.   CIRCULATION

H 2 S Protects Against Pressure Overload–Induced Heart Failure via Upregulation of Endothelial Nitric Oxide Synthase

(2013) Kazuhisa Kondo et al.   CIRCULATION

Hydrogen Sulfide Prevents Hyperoxia-induced Lung Injury by Downregulating Reactive Oxygen Species Formation and Angiopoietin-2 Release

(2013) Simone Faller et al.   CURRENT PHARMACEUTICAL DESIGN

Treatment with exogenous hydrogen sulfide attenuates hyperoxia-induced acute lung injury in mice

(2013) Huai-Dong Li et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Hydrogen sulfide inhibits high-glucose-induced apoptosis in neonatal rat cardiomyocytes

(2013) Xiang Zhou et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Polysulfides are possible H2S-derived signaling molecules in rat brain

(2013) Yuka Kimura et al.   FASEB JOURNAL

Microbial regulation of host hydrogen sulfide bioavailability and metabolism

(2013) Xinggui Shen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibition of NADPH oxidase 4-related signaling by sodium hydrosulfide attenuates myocardial fibrotic response

(2013) Li-Long Pan et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Structure and Kinetic Analysis of H2S Production by Human Mercaptopyruvate Sulfurtransferase

(2013) Pramod Kumar Yadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crosstalk between hydrogen sulfide and nitric oxide in endothelial cells

(2013) Zaid Altaany et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

L-cysteine and hydrogen sulfide increase PIP3 and AMPK/PPARγ expression and decrease ROS and vascular inflammation markers in high glucose treated human U937 monocytes

(2013) Prasenjit Manna et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

TRPA1 Channels Are Regulators of Astrocyte Basal Calcium Levels and Long-Term Potentiation via Constitutive D-Serine Release

(2013) E. Shigetomi et al.   JOURNAL OF NEUROSCIENCE

Postural Orthostatic Tachycardia Syndrome with Increased Erythrocytic Hydrogen Sulfide and Response to Midodrine Hydrochloride

(2013) Jinyan Yang et al.   JOURNAL OF PEDIATRICS

Acetylcholine- and Sodium Hydrosulfide^|^ndash;Induced Endothelium-Dependent Relaxation and Hyperpolarization in Cerebral Vessels of Global Cerebral Ischemia^|^ndash;Reperfusion Rat

(2013) Jun Han et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Hydrogen sulphide inhibits Ca2+release through InsP3receptors and relaxes airway smooth muscle

(2013) Isabel Castro-Piedras et al.   JOURNAL OF PHYSIOLOGY-LONDON

Effect of endogenous hydrogen sulfide on the transwall gradient of the mouse colon circular smooth muscle

(2013) L. Sha et al.   JOURNAL OF PHYSIOLOGY-LONDON

Protective effects of hydrogen sulfide in a rat model of traumatic brain injury via activation of mitochondrial adenosine triphosphate–sensitive potassium channels and reduction of oxidative stress

(2013) Xiaofan Jiang et al.   JOURNAL OF SURGICAL RESEARCH

Cystathionine  -Lyase Protects against Renal Ischemia/Reperfusion by Modulating Oxidative Stress

(2013) E. M. Bos et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hydrogen Sulfide Mediated Inhibitory Neurotransmission to the Pig Bladder Neck: Role of KATP Channels, Sensory Nerves and Calcium Signaling

(2013) Vítor S. Fernandes et al.   JOURNAL OF UROLOGY

Hydrogen sulfide inhibits the renal fibrosis of obstructive nephropathy

(2013) Kai Song et al.   KIDNEY INTERNATIONAL

Expression levels of endogenous hydrogen sulfide are altered in patients with allergic rhinitis

(2013) Se Jin Park et al.   LARYNGOSCOPE

Thrombospondin-1 is a CD47-dependent endogenous inhibitor of hydrogen sulfide signaling in T cell activation

(2013) Thomas W. Miller et al.   MATRIX BIOLOGY

Estrogens increase cystathionine-γ-lyase expression and decrease inflammation and oxidative stress in the myocardium of ovariectomized rats

(2013) Xiaoyan Zhu et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Hydrogen sulphide vasodilates human pulmonary arteries: A possible role in pulmonary hypertension?

(2013) Priyadharshanan Ariyaratnam et al.   MICROVASCULAR RESEARCH

Hydrogen Sulfide, the Next Potent Preventive and Therapeutic Agent in Aging and Age-Associated Diseases

(2013) Yuan Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Hydrogen sulfide prevents H2O2-induced senescence in human umbilical vein endothelial cells through SIRT1 activation

(2013) RONG SUO et al.   Molecular Medicine Reports

Hydrogen Sulfide Increases Excitability through Suppression of Sustained Potassium Channel Currents of Rat Trigeminal Ganglion Neurons

(2013) Xingmei Feng et al.   Molecular Pain

Bile acid receptors as targets for drug development

(2013) Frank G. Schaap et al.   Nature Reviews Gastroenterology & Hepatology

An investigation of the mechanisms of hydrogen sulfide-induced vasorelaxation in rat middle cerebral arteries

(2013) E. Streeter et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Physiological role of hydrogen sulfide and polysulfide in the central nervous system

(2013) Hideo Kimura   NEUROCHEMISTRY INTERNATIONAL

Effects of H2S on the central regulation of respiration in adult rats

(2013) Hui Li et al.   NEUROREPORT

l-Cysteine promotes the proliferation and differentiation of neural stem cells via the CBS/H2S pathway

(2013) Z. Wang et al.   NEUROSCIENCE

Hydrogen sulfide attenuates neurodegeneration and neurovascular dysfunction induced by intracerebral-administered homocysteine in mice

(2013) P.K. Kamat et al.   NEUROSCIENCE

Exogenous hydrogen sulfide prevents kidney damage following unilateral ureteral obstruction

(2013) Dapeng Jiang et al.   NEUROUROLOGY AND URODYNAMICS

OP16 Hydrogen sulfide inhibits human platelet aggregation

(2013) Zeki Ilkan et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Chemical foundations of hydrogen sulfide biology

(2013) Qian Li et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Core myopathies and malignant hyperthermia susceptibility: a review

(2013) Robert P. Brislin et al.   PEDIATRIC ANESTHESIA

GluN2A and GluN2B subunit-containing NMDA receptors in hippocampal plasticity

(2013) O. A. Shipton et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Hydrogen Sulfide Reduces Neutrophil Recruitment in Hind-Limb Ischemia-Reperfusion Injury in an L-Selectin and ADAM-17–Dependent Manner

(2013) Carissa J. Ball et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Effect of the hydrogen sulfide donor GYY4137 on platelet activation and microvascular thrombus formation in mice

(2013) Eberhard Grambow et al.   PLATELETS

Brain 3-Mercaptopyruvate Sulfurtransferase (3MST): Cellular Localization and Downregulation after Acute Stroke

(2013) Heng Zhao et al.   PLoS One

Depolarizing Actions of Hydrogen Sulfide on Hypothalamic Paraventricular Nucleus Neurons

(2013) C. Sahara Khademullah et al.   PLoS One

Hydrogen Sulfide Preconditioning Protects Rat Liver against Ischemia/Reperfusion Injury by Activating Akt-GSK-3β Signaling and Inhibiting Mitochondrial Permeability Transition

(2013) Qingqing Zhang et al.   PLoS One

H2S Inhibits Hyperglycemia-Induced Intrarenal Renin-Angiotensin System Activation via Attenuation of Reactive Oxygen Species Generation

(2013) Hong Xue et al.   PLoS One

C. elegans Aging Is Modulated by Hydrogen Sulfide and the sulfhydrylase/cysteine Synthase cysl-2

(2013) Bedoor Qabazard et al.   PLoS One

Cystathionine Beta-Synthase (CBS) Contributes to Advanced Ovarian Cancer Progression and Drug Resistance

(2013) Sanjib Bhattacharyya et al.   PLoS One

Tumor-derived hydrogen sulfide, produced by cystathionine- -synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer

(2013) C. Szabo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxygen-sensitive mitochondrial accumulation of cystathionine  -synthase mediated by Lon protease

(2013) H. Teng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The anti-thrombotic effect of hydrogen sulfide is partly mediated by an upregulation of nitric oxide synthases

(2013) Lukas Kram et al.   THROMBOSIS RESEARCH

Altered Sulfide (H2S) Metabolism in Ethylmalonic Encephalopathy

(2013) V. Tiranti et al.   Cold Spring Harbor Perspectives in Biology

A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells

(2013) Norihiro Shibuya et al.   Nature Communications

Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria

(2013) Noriyuki Nagahara et al.   Scientific Reports

Evolution of Hemoglobin and Its Genes

(2013) R. C. Hardison   Cold Spring Harbor Perspectives in Medicine

Hydrogen Sulfide Stimulates Ischemic Vascular Remodeling Through Nitric Oxide Synthase and Nitrite Reduction Activity Regulating Hypoxia‐Inducible Factor‐1α and Vascular Endothelial Growth Factor–Dependent Angiogenesis

(2013) Shyamal C. Bir et al.   Journal of the American Heart Association

Multiple ways to die: Non-apoptotic forms of cell death

(2012) Yoshihide Tsujimoto   ACTA ONCOLOGICA

Endogenous hydrogen sulfide insufficiency as a predictor of sexual dysfunction in aging rats

(2012) Balasubramanian Srilatha et al.   Aging Male

H2S, a gasotransmitter for oxygen sensing in carotid body. Focus on “Endogenous H2S is required for hypoxic sensing by carotid body glomus cells”

(2012) Kimberly A. Smith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Increased endogenous H2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia

(2012) Utpal Sen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Endogenous H2S is required for hypoxic sensing by carotid body glomus cells

(2012) Vladislav V. Makarenko et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hydrogen sulfide protects SH-SY5Y cells against 6-hydroxydopamine-induced endoplasmic reticulum stress

(2012) Li Xie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The polysulfide diallyl trisulfide protects the ischemic myocardium by preservation of endogenous hydrogen sulfide and increasing nitric oxide bioavailability

(2012) Benjamin L. Predmore et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

A Large Subgroup of Mild-to-Moderate Asthma Is Persistently Noneosinophilic

(2012) Kelly Wong McGrath et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

High Turnover Rates for Hydrogen Sulfide Allow for Rapid Regulation of Its Tissue Concentrations

(2012) Victor Vitvitsky et al.   ANTIOXIDANTS & REDOX SIGNALING

The Neuroprotection of Hydrogen Sulfide Against MPTP-Induced Dopaminergic Neuron Degeneration Involves Uncoupling Protein 2 Rather Than ATP-Sensitive Potassium Channels

(2012) Ming Lu et al.   ANTIOXIDANTS & REDOX SIGNALING

Detoxification of H2S by Differentiated Colonic Epithelial Cells: Implication of the Sulfide Oxidizing Unit and of the Cell Respiratory Capacity

(2012) Sabria Mimoun et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of Mercaptopyruvate Sulfurtransferase Activity Via Intrasubunit and Intersubunit Redox-Sensing Switches

(2012) Noriyuki Nagahara   ANTIOXIDANTS & REDOX SIGNALING

Myeloperoxidase: A Leukocyte-Derived Protagonist of Inflammation and Cardiovascular Disease

(2012) Claudia Nussbaum et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide Protects Against Cellular Senescence via S-Sulfhydration of Keap1 and Activation of Nrf2

(2012) Guangdong Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

VEGFR2 Functions As an H2S-Targeting Receptor Protein Kinase with Its Novel Cys1045–Cys1024 Disulfide Bond Serving As a Specific Molecular Switch for Hydrogen Sulfide Actions in Vascular Endothelial Cells

(2012) Bei-Bei Tao et al.   ANTIOXIDANTS & REDOX SIGNALING

The Gasotransmitter Hydrogen Sulfide Induces Nrf2-Target Genes by Inactivating the Keap1 Ubiquitin Ligase Substrate Adaptor Through Formation of a Disulfide Bond Between Cys-226 and Cys-613

(2012) John M. Hourihan et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide–Releasing Aspirin Derivative ACS14 Exerts Strong Antithrombotic Effects In Vitro and In Vivo

(2012) Joachim Pircher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The role of AKT1 and autophagy in the protective effect of hydrogen sulphide against hepatic ischemia/reperfusion injury in mice

(2012) Dawei Wang et al.   Autophagy

Hydrogen sulfide decreases the levels of ROS by inhibiting mitochondrial complex IV and increasing SOD activities in cardiomyocytes under ischemia/reperfusion

(2012) Wei-Hua Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Novel structural arrangement of nematode cystathionine β-synthases: characterization ofCaenorhabditis elegansCBS-1

(2012) Roman Vozdek et al.   BIOCHEMICAL JOURNAL

Role of endogenous hydrogen sulfide in neurogenic relaxation of rat corpus cavernosum

(2012) Mehdi Ghasemi et al.   BIOCHEMICAL PHARMACOLOGY

Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras

(2012) Khosrow Kashfi et al.   BIOCHEMICAL PHARMACOLOGY

Human Sulfide:Quinone Oxidoreductase Catalyzes the First Step in Hydrogen Sulfide Metabolism and Produces a Sulfane Sulfur Metabolite

(2012) Michael R. Jackson et al.   BIOCHEMISTRY

Supplemental hydrogen sulphide protects transplant kidney function and prolongs recipient survival after prolonged cold ischaemia-reperfusion injury by mitigating renal graft apoptosis and inflammation

(2012) Ian Lobb et al.   BJU INTERNATIONAL

Detrimental effects of prolonged warm renal ischaemia-reperfusion injury are abrogated by supplemental hydrogen sulphide: an analysis using real-time intravital microscopy and polymerase chain reaction

(2012) Justin X.G. Zhu et al.   BJU INTERNATIONAL

Transplant tolerance is associated with reduced expression of cystathionine- -lyase that controls IL-12 production by dendritic cells and TH-1 immune responses

(2012) R. Vuillefroy de Silly et al.   BLOOD

The gasotransmitter hydrogen sulphide decreases Na+ transport across pulmonary epithelial cells

(2012) M Althaus et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of the bile acid receptor GPBAR1 protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs and aspirin in mice

(2012) Sabrina Cipriani et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hydrogen sulfide inhibits the translational expression of hypoxia-inducible factor-1α

(2012) Bo Wu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Platelet-derived growth factor-BB induces cystathionine γ-lyase expression in rat mesangial cells via a redox-dependent mechanism

(2012) Mohamed I. Hassan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Involvement of the endogenous hydrogen sulfide/Cav3.2 T-type Ca2+channel pathway in cystitis-related bladder pain in mice

(2012) Maho Matsunami et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hydrogen sulfide-induced mechanical hyperalgesia and allodynia require activation of both Cav3.2 and TRPA1 channels in mice

(2012) Kazumasa Okubo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hydrogen sulphide-mediated vasodilatation involves the release of neurotransmitters from sensory nerves in pressurized mesenteric small arteries isolated from rats

(2012) Benjamin J O White et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hydrogen sulphide-induced relaxation of porcine peripheral bronchioles

(2012) S Rashid et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effects of hydrogen sulphide in an experimental model of renal ischaemia-reperfusion injury

(2012) J. P. Hunter et al.   BRITISH JOURNAL OF SURGERY

Distribution of H2S Synthesis Enzymes in the Walls of Cerebral Arteries in Rats

(2012) V. M. Chertok et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Endogenous CSE/H2S system mediates TNF-α-induced insulin resistance in 3T3-L1 adipocytes

(2012) Ci-You Huang et al.   CELL BIOCHEMISTRY AND FUNCTION

Sp1 is involved in regulation of cystathionine γ-lyase gene expression and biological function by PI3K/Akt pathway in human hepatocellular carcinoma cell lines

(2012) Peng Yin et al.   CELLULAR SIGNALLING

Small Molecule Signaling Agents: The Integrated Chemistry and Biochemistry of Nitrogen Oxides, Oxides of Carbon, Dioxygen, Hydrogen Sulfide, and Their Derived Species

(2012) Jon M. Fukuto et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Distribution of hydrogen sulfide (H2S)-producing enzymes and the roles of the H2S donor sodium hydrosulfide in diabetic nephropathy

(2012) Junichiro Yamamoto et al.   Clinical and Experimental Nephrology

Antioxidative properties of hydrogen sulfide may involve in its antiadhesive action on blood platelets

(2012) Agnieszka Morel et al.   CLINICAL BIOCHEMISTRY

Hydrogen sulfide-induced inhibition of L-type Ca2+ channels and insulin secretion in mouse pancreatic beta cells

(2012) G. Tang et al.   DIABETOLOGIA

Hydrogen Sulfide Impairs Glucose Utilization and Increases Gluconeogenesis in Hepatocytes

(2012) Ling Zhang et al.   ENDOCRINOLOGY

The role of endogenous hydrogen sulfide in pathogenesis of chronotropic dysfunction in rats with cirrhosis

(2012) Mohammad Babaei-Karamshahlou et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of KATP channels and TRPV1 receptors in hydrogen sulfide-enhanced gastric emptying of liquid in awake mice

(2012) Jand Venes R. Medeiros et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hydrogen sulfide inhibits oxidative stress in lungs from allergic mice in vivo

(2012) Leticia R. Benetti et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Sildenafil Effect on the Human Bladder Involves the L-cysteine/Hydrogen Sulfide Pathway: A Novel Mechanism of Action of Phosphodiesterase Type 5 Inhibitors

(2012) Ferdinando Fusco et al.   EUROPEAN UROLOGY

Hydrogen sulfide inhibits preoptic prostaglandin E2 production during endotoxemia

(2012) Marcelo Kwiatkoski et al.   EXPERIMENTAL NEUROLOGY

Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics

(2012) Katalin Módis et al.   FASEB JOURNAL

Vitamin D3 (Cholecalciferol) Boosts Hydrogen Sulfide Tissue Concentrations in Heart and other Mouse Organs

(2012) Bogdan Wiliński et al.   FOLIA BIOLOGICA-KRAKOW

Analytical measurement of discrete hydrogen sulfide pools in biological specimens

(2012) Xinggui Shen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Formation of reactive sulfite-derived free radicals by the activation of human neutrophils: An ESR study

(2012) Kalina Ranguelova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vitamin D Up-regulates Glucose Transporter 4 (GLUT4) Translocation and Glucose Utilization Mediated by Cystathionine-γ-lyase (CSE) Activation and H2S Formation in 3T3L1 Adipocytes

(2012) Prasenjit Manna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Total Plasma Sulfide in Congestive Heart Failure

(2012) Dragan Kovačić et al.   JOURNAL OF CARDIAC FAILURE

Mitochondrial adaptations to utilize hydrogen sulfide for energy and signaling

(2012) Kenneth R. Olson   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

The role of endogenous H2S formation in reversible remodeling of lung tissue during hibernation in the Syrian hamster

(2012) F. Talaei et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Gaseous messengers in oxygen sensing

(2012) Nanduri R. Prabhakar et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Hydrogen sulfide activates Ca2+sparks to induce cerebral arteriole dilatation

(2012) Guo Hua Liang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Contribution of Flow-Dependent Vasomotor Mechanisms to the Autoregulation of Cerebral Blood Flow

(2012) Akos Koller et al.   JOURNAL OF VASCULAR RESEARCH

The Princeton III Consensus Recommendations for the Management of Erectile Dysfunction and Cardiovascular Disease

(2012) Ajay Nehra et al.   MAYO CLINIC PROCEEDINGS

Exogenous hydrogen sulfide attenuates diabetic myocardial injury through cardiac mitochondrial protection

(2012) Xin Zhong et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Hydrogen Sulfide-Linked Sulfhydration of NF-κB Mediates Its Antiapoptotic Actions

(2012) Nilkantha Sen et al.   MOLECULAR CELL

17 -estradiol induces vasorelaxation by stimulating endothelial hydrogen sulfide release

(2012) K. Zhou et al.   MOLECULAR HUMAN REPRODUCTION

Protective effects of hydrogen sulfide on oxidative stress and fibrosis in hepatic stellate cells

(2012) HAI-NING FAN et al.   Molecular Medicine Reports

Correlation between serum H2S and pulmonary function in children with bronchial asthma

(2012) MAN TIAN et al.   Molecular Medicine Reports

Radioprotective role of H2S/CSE pathway in Chang liver cells

(2012) Yan Pan et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Contributions of the microbial hydrogen economy to colonic homeostasis

(2012) Franck Carbonero et al.   Nature Reviews Gastroenterology & Hepatology

Synergizing Genomic Analysis With Biological Knowledge to Identify and Validate Novel Genes in Pancreatic Development

(2012) Suparna A. Sarkar et al.   PANCREAS

Effects of exogenous hydrogen sulphide on calcium signalling, background (TASK) K channel activity and mitochondrial function in chemoreceptor cells

(2012) Keith J. Buckler   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Cystathionine β-synthase deficiency causes infertility by impairing decidualization and gene expression networks in uterus implantation sites

(2012) Mario Nuño-Ayala et al.   PHYSIOLOGICAL GENOMICS

Hydrogen sulfide producing enzymes in pregnancy and preeclampsia

(2012) K.M. Holwerda et al.   PLACENTA

Cysteine-Generated Sulfide in the Cytosol Negatively Regulates Autophagy and Modulates the Transcriptional Profile in Arabidopsis

(2012) C. Alvarez et al.   PLANT CELL

Solubility and Permeation of Hydrogen Sulfide in Lipid Membranes

(2012) Ernesto Cuevasanta et al.   PLoS One

Hydrogen Sulfide Inhibits L-Type Calcium Currents Depending upon the Protein Sulfhydryl State in Rat Cardiomyocytes

(2012) Rongyuan Zhang et al.   PLoS One

Interaction of Hydrogen Sulfide and Estrogen on the Proliferation of Vascular Smooth Muscle Cells

(2012) Hongzhu Li et al.   PLoS One

PI3K p110α Isoform-Dependent Rho GTPase Rac1 Activation Mediates H2S-Promoted Endothelial Cell Migration via Actin Cytoskeleton Reorganization

(2012) Li-Jia Zhang et al.   PLoS One

TRPA1 Has a Key Role in the Somatic Pro-Nociceptive Actions of Hydrogen Sulfide

(2012) David A. Andersson et al.   PLoS One

Hydrogen Sulfide Suppresses Outward Rectifier Potassium Currents in Human Pluripotent Stem Cell-Derived Cardiomyocytes

(2012) Heming Wei et al.   PLoS One

Hydrogen Sulfide in Paraventricular Nucleus Enhances Sympathetic Activity and Cardiac Sympathetic Afferent Reflex in Chronic Heart Failure Rats

(2012) Xian-Bing Gan et al.   PLoS One

cGMP-Dependent Protein Kinase Contributes to Hydrogen Sulfide-Stimulated Vasorelaxation

(2012) Mariarosaria Bucci et al.   PLoS One

Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production

(2012) M. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Folding and activity of mutant cystathionine β-synthase depends on the position and nature of the purification tag: Characterization of the R266K CBS mutant

(2012) Tomas Majtan et al.   PROTEIN EXPRESSION AND PURIFICATION

Physiologic Uterine Inflammation and Labor Onset

(2012) Oksana Shynlova et al.   Reproductive Sciences

Endogenous hydrogen sulfide formation mediates the liver damage in endotoxemic rats

(2012) Yulin Yan et al.   RESEARCH IN VETERINARY SCIENCE

Unique membrane process integration for olive oil mill wastewater purification

(2012) Alireza Zirehpour et al.   SEPARATION AND PURIFICATION TECHNOLOGY

TEMPERATURE AND CELL-TYPE DEPENDENCY OF SULFIDE EFFECTS ON MITOCHONDRIAL RESPIRATION

(2012) Michael Groeger et al.   SHOCK

Hydrogen Sulfide Differentially Affects The Hepatic Vasculature In Response To Phenylephrine And Endothelin 1 During Endotoxemia

(2012) Eric J. Norris et al.   SHOCK

Hydrogen Sulfide Protects Cardiomyocytes from Myocardial Ischemia-Reperfusion Injury by Enhancing Phosphorylation of Apoptosis Repressor with Caspase Recruitment Domain

(2012) Xiaoyi Yao et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Beneficial effects of gaseous hydrogen sulfide in hepatic ischemia/reperfusion injury

(2012) Eelke M. Bos et al.   TRANSPLANT INTERNATIONAL

Halitosis andHelicobacter pyloriinfection

(2012) A Tangerman et al.   Journal of Breath Research

Endogenous hydrogen sulfide mediates the cardioprotection induced by ischemic postconditioning in the early reperfusion phase

(2012) YI-E HUANG et al.   Experimental and Therapeutic Medicine

Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe

(2012) Neil Dufton et al.   Scientific Reports

A Systematic Analysis of Cell Cycle Regulators in Yeast Reveals That Most Factors Act Independently of Cell Size to Control Initiation of Division

(2012) Scott A. Hoose et al.   PLoS Genetics

Gasotransmitters: Novel Regulators of Epithelial Na+ Transport?

(2012) Mike Althaus   Frontiers in Physiology

The vasorelaxing effect of hydrogen sulfide on isolated rat aortic rings versus pulmonary artery rings

(2011) Yan Sun et al.   ACTA PHARMACOLOGICA SINICA

Propofol increases the Ca2+ sensitivity of BKCa in the cerebral arterial smooth muscle cells of mice

(2011) Xue-ru Liu et al.   ACTA PHARMACOLOGICA SINICA

The Pathogenic Role of Cystathionine γ-Lyase/Hydrogen Sulfide in Streptozotocin-Induced Diabetes in Mice

(2011) Guangdong Yang et al.   AMERICAN JOURNAL OF PATHOLOGY

Hydrogen sulfide regulates cAMP homeostasis and renin degranulation in As4.1 and rat renin-rich kidney cells

(2011) Ming Lu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Eukaryotic and prokaryotic contributions to colonic hydrogen sulfide synthesis

(2011) Kyle L. Flannigan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Hydrogen sulfide preconditioning or neutrophil depletion attenuates ischemia-reperfusion-induced mitochondrial dysfunction in rat small intestine

(2011) Yajun Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Hydrogen sulfide dilates cerebral arterioles by activating smooth muscle cell plasma membrane KATP channels

(2011) Guo Hua Liang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Antecedent hydrogen sulfide elicits an anti-inflammatory phenotype in postischemic murine small intestine: role of heme oxygenase-1

(2011) Mozow Y. Zuidema et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The therapeutic potential of hydrogen sulfide: separating hype from hope

(2011) Kenneth R. Olson   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Hydrogen Sulfide Inhibits Proliferation and Release of IL-8 from Human Airway Smooth Muscle Cells

(2011) Mark M. Perry et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

(2011) Ulf Andersson et al.   Annual Review of Immunology

Hydrogen Sulfide and Cell Signaling

(2011) Ling Li et al.   Annual Review of Pharmacology and Toxicology

The Quantitative Significance of the Transsulfuration Enzymes for H2S Production in Murine Tissues

(2011) Omer Kabil et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide Ameliorates Tobacco Smoke-Induced Oxidative Stress and Emphysema in Mice

(2011) Weihong Han et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide: An Endogenous Mediator of Resolution of Inflammation and Injury

(2011) John L. Wallace et al.   ANTIOXIDANTS & REDOX SIGNALING

Roles of Hydrogen Sulfide in the Pathogenesis of Diabetes Mellitus and Its Complications

(2011) Csaba Szabo   ANTIOXIDANTS & REDOX SIGNALING

Delivery of the Bioactive Gas Hydrogen Sulfide During Cold Preservation of Rat Liver: Effects on Hepatic Function in an Ex vivo Model

(2011) Cecilia L. Balaban et al.   ARTIFICIAL ORGANS

Hydrogen sulphide inhibits cardiomyocyte hypertrophy by up-regulating miR-133a

(2011) Jun Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide

(2011) Yoshinori Mikami et al.   BIOCHEMICAL JOURNAL

Biochemical insight into physiological effects of H2S: reaction with peroxynitrite and formation of a new nitric oxide donor, sulfinyl nitrite

(2011) Milos R. Filipovic et al.   BIOCHEMICAL JOURNAL

PLP-dependent H2S biogenesis

(2011) Sangita Singh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Malignant hyperthermia: pharmacology of triggering

(2011) P.M. Hopkins   BRITISH JOURNAL OF ANAESTHESIA

Effects of inhibitors of hydrogen sulphide synthesis on rat colonic motility

(2011) V Gil et al.   BRITISH JOURNAL OF PHARMACOLOGY

Sulphide quinone reductase contributes to hydrogen sulphide metabolism in murine peripheral tissues but not in the CNS

(2011) DR Linden et al.   BRITISH JOURNAL OF PHARMACOLOGY

Principal role of adenylyl cyclase 6 in K+ channel regulation and vasodilator signalling in vascular smooth muscle cells

(2011) Carl P. Nelson et al.   CARDIOVASCULAR RESEARCH

Intermittent Hypoxia in Rats Increases Myogenic Tone Through Loss of Hydrogen Sulfide Activation of Large-Conductance Ca 2+ -Activated Potassium Channels

(2011) Olan Jackson-Weaver et al.   CIRCULATION RESEARCH

Hydrogen Sulfide as Endothelium-Derived Hyperpolarizing Factor Sulfhydrates Potassium Channels

(2011) Asif K. Mustafa et al.   CIRCULATION RESEARCH

Myocardial and lung injuries induced by hydrogen sulfide and the effectiveness of oxygen therapy in rats

(2011) Na Wu et al.   CLINICAL TOXICOLOGY

Rat pancreatic level of cystathionine γ-lyase is regulated by glucose level via specificity protein 1 (SP1) phosphorylation

(2011) L. Zhang et al.   DIABETOLOGIA

Evidence that endogenous hydrogen sulfide exerts an excitatory effect on gastric motility in mice

(2011) Yan-fei Han et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hydrogen sulfide and asthma

(2011) Peipei Wang et al.   EXPERIMENTAL PHYSIOLOGY

Cytoprotective actions of hydrogen sulfide in ischaemia-reperfusion injury

(2011) Adrienne L. King et al.   EXPERIMENTAL PHYSIOLOGY

A critical life-supporting role for cystathionine γ-lyase in the absence of dietary cysteine supply

(2011) Sarathi Mani et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hydrogen sulfide promotes calcium signals and migration in tumor-derived endothelial cells

(2011) Emanuela Pupo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Measurement of plasma hydrogen sulfide in vivo and in vitro

(2011) Xinggui Shen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hydrogen sulfide protects MC3T3-E1 osteoblastic cells against H2O2-induced oxidative damage—implications for the treatment of osteoporosis

(2011) Zhong-Shi Xu et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Response ofCaenorhabditis elegansto Hydrogen Sulfide and Hydrogen Cyanide

(2011) Mark W. Budde et al.   GENETICS

Generation of gaseous sulfur-containing compounds in tumour tissue and suppression of gas diffusion as an antitumour treatment

(2011) Kazue Yamagishi et al.   GUT

Hydrogen sulfide inhibits the spontaneous and oxytocin-induced contractility of human pregnant myometrium

(2011) Rong Hu et al.   GYNECOLOGICAL ENDOCRINOLOGY

A Fatal Case of Acute Hydrogen Sulfide Poisoning Caused by Hydrogen Sulfide: Hydroxocobalamin Therapy for Acute Hydrogen Sulfide Poisoning

(2011) Y. Fujita et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Hydrogen Sulfide Inhibits High Glucose-induced Matrix Protein Synthesis by Activating AMP-activated Protein Kinase in Renal Epithelial Cells

(2011) Hak Joo Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specificity Protein-1 as a Critical Regulator of Human Cystathionine γ-Lyase in Smooth Muscle Cells

(2011) Guangdong Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase

(2011) Carsten Kriebitzsch et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Hydrogen Sulfide

(2011) Yi-Hong Liu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Hydrogen Sulfide Protects Against High-glucose–induced Apoptosis in Endothelial Cells

(2011) Qingbo Guan et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

(2011) Philippe Ravassard et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of Hydrogen Sulfide as a Gasotransmitter in Modulating Contractile Activity of Circular Muscle of Rat Jejunum

(2011) Munenori Nagao et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Hydrogen Sulfide Upregulates Cyclooxygenase-2 and Prostaglandin E Metabolite in Sepsis-Evoked Acute Lung Injury via Transient Receptor Potential Vanilloid Type 1 Channel Activation

(2011) S.-F. Ang et al.   JOURNAL OF IMMUNOLOGY

Increased neointimal formation in cystathionine gamma-lyase deficient mice: Role of hydrogen sulfide in α5β1-integrin and matrix metalloproteinase-2 expression in smooth muscle cells

(2011) Guangdong Yang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Hydrogen sulfide augments synaptic neurotransmission in the nucleus of the solitary tract

(2011) James R. Austgen et al.   JOURNAL OF NEUROPHYSIOLOGY

Hydrogen Sulfide in the Rostral Ventrolateral Medulla Inhibits Sympathetic Vasomotor Tone through ATP-Sensitive K+ Channels

(2011) Q. Guo et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Hydrogen Sulfide-Induced Dual Vascular Effect Involves Arachidonic Acid Cascade in Rat Mesenteric Arterial Bed

(2011) R. d'Emmanuele di Villa Bianca et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Hydrogen Sulfide Modulates Contractile Function in Rat Jejunum

(2011) Michael S. Kasparek et al.   JOURNAL OF SURGICAL RESEARCH

Erectile Dysfunction and Risk of Cardiovascular Disease

(2011) Jia-Yi Dong et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Hydrogen sulfide inhibits the calcification and osteoblastic differentiation of vascular smooth muscle cells

(2011) Erzsébet Zavaczki et al.   KIDNEY INTERNATIONAL

Hydrogen sulfide protects H9c2 cells against doxorubicin-induced cardiotoxicity through inhibition of endoplasmic reticulum stress

(2011) Xiu-Yu Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3

(2011) Eiji Shigetomi et al.   NATURE NEUROSCIENCE

Common architecture of the flagellar type III protein export apparatus and F- and V-type ATPases

(2011) Tatsuya Ibuki et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide

(2011) P. Yuan et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Effects of hydrogen sulfide on the exo- and endocytosis of synaptic vesicles in frog motor nerve endings

(2011) G. F. Sitdikova et al.   Neurochemical Journal

Endogenous Production of Hydrogen Sulfide in Isolated Bovine Eye

(2011) Madhura Kulkarni et al.   NEUROCHEMICAL RESEARCH

Inhibition of T-type calcium channels and hydrogen sulfide-forming enzyme reverses paclitaxel-evoked neuropathic hyperalgesia in rats

(2011) K. Okubo et al.   NEUROSCIENCE

Effects of Hydrogen Sulfide on Rat Pancreatic Stellate Cells

(2011) Christian I. Schwer et al.   PANCREAS

NaHS relaxes rat cerebral artery in vitro via inhibition of l-type voltage-sensitive Ca2+ channel

(2011) Xiao Yu Tian et al.   PHARMACOLOGICAL RESEARCH

H2S Donor, S-Propargyl-Cysteine, Increases CSE in SGC-7901 and Cancer-Induced Mice: Evidence for a Novel Anti-Cancer Effect of Endogenous H2S?

(2011) Kaium MA et al.   PLoS One

Expression of Cystathionine β-synthase and Cystathionine γ-lyase in Human Pregnant Myometrium and Their Roles in the Control of Uterine Contractility

(2011) Xing-Ji You et al.   PLoS One

HIF-1 and SKN-1 Coordinate the Transcriptional Response to Hydrogen Sulfide in Caenorhabditis elegans

(2011) Dana L. Miller et al.   PLoS One

Hydrogen Sulfide Attenuates Carbon Tetrachloride-Induced Hepatotoxicity, Liver Cirrhosis and Portal Hypertension in Rats

(2011) Gang Tan et al.   PLoS One

On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN)

(2011) N. Numajiri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Hydrogen Sulfide Synthesis Inhibitors on Posthypoxic Ventilatory Behavior in the C57BL/6J Mouse

(2011) Lucas M. Donovan et al.   RESPIRATION

Hydrogen sulfide oxidation and the arterial chemoreflex: Effect of methemoglobin

(2011) Philippe Haouzi et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Hypoxia-induced arterial chemoreceptor stimulation and Hydrogen sulfide: Too much or too little?

(2011) Philippe Haouzi et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

The impact of hydrogen sulfide (H2S) on neurotransmitter release from the cat carotid body

(2011) Robert S. Fitzgerald et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

H2S: A Universal Defense Against Antibiotics in Bacteria

(2011) K. Shatalin et al.   SCIENCE

The Liver as a Central Regulator of Hydrogen Sulfide

(2011) Eric J. Norris et al.   SHOCK

Inhaled Hydrogen Sulfide Induces Suspended Animation, But Does Not Alter the Inflammatory Response After Blunt Chest Trauma

(2011) Daniel H. Seitz et al.   SHOCK

Hydrogen sulfide mediates the anti-survival effect of sulforaphane on human prostate cancer cells

(2011) Yanxi Pei et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The hydrogen sulfide signaling system: changes during aging and the benefits of caloric restriction

(2010) Benjamin L. Predmore et al.   AGE

Hydrogen Sulfide Regulates Homocysteine-Mediated Glomerulosclerosis

(2010) Utpal Sen et al.   AMERICAN JOURNAL OF NEPHROLOGY

Hydrogen sulfide protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis by preventing GSK-3β-dependent opening of mPTP

(2010) Ling-Ling Yao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Antecedent hydrogen sulfide elicits an anti-inflammatory phenotype in postischemic murine small intestine: role of BK channels

(2010) Mozow Y. Zuidema et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Vascular complications of cystathionine β-synthase deficiency: future directions for homocysteine-to-hydrogen sulfide research

(2010) Richard S. Beard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hydrogen sulfide and cerebral microvascular tone in newborn pigs

(2010) Charles W. Leffler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Inhaled Hydrogen Sulfide Protects against Ventilator-induced Lung Injury

(2010) Simone Faller et al.   ANESTHESIOLOGY

Free and Acid-Labile Hydrogen Sulfide Concentrations in Mouse Tissues: Anomalously High Free Hydrogen Sulfide in Aortic Tissue

(2010) Michael D. Levitt et al.   ANTIOXIDANTS & REDOX SIGNALING

Differential Dependence on Cysteine from Transsulfuration versus Transport During T Cell Activation

(2010) Sanjay K. Garg et al.   ANTIOXIDANTS & REDOX SIGNALING

Structural determinants for the formation of sulfhemeprotein complexes

(2010) Elddie Román-Morales et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sulfide Binding Properties of Truncated Hemoglobins

(2010) Francesco P. Nicoletti et al.   BIOCHEMISTRY

Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes

(2010) Emilie Lagoutte et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Detection of exhaled hydrogen sulphide gas in healthy human volunteers during intravenous administration of sodium sulphide

(2010) Christopher F. Toombs et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

A monobromobimane-based assay to measure the pharmacokinetic profile of reactive sulphide species in blood

(2010) Edward A Wintner et al.   BRITISH JOURNAL OF PHARMACOLOGY

Differing effects of exogenous and endogenous hydrogen sulphide in carrageenan-induced knee joint synovitis in the rat

(2010) E Ekundi-Valentim et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells

(2010) Guangdong Yang et al.   CARDIOVASCULAR RESEARCH

Hydrogen sulfide induces human colon cancer cell proliferation: role of Akt, ERK and p21

(2010) Wen‑Jie Cai et al.   CELL BIOLOGY INTERNATIONAL

Glucocorticoids suppress cystathionine gamma-lyase expression and H2S production in lipopolysaccharide-treated macrophages

(2010) Xiao-Yan Zhu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Rapid Reaction of Hydrogen Sulfide with the Neutrophil Oxidant Hypochlorous Acid to Generate Polysulfides

(2010) Péter Nagy et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Genetic and Pharmacologic Hydrogen Sulfide Therapy Attenuates Ischemia-Induced Heart Failure in Mice

(2010) John W. Calvert et al.   CIRCULATION

Involvement of endogenous hydrogen sulfide in cigarette smoke-induced changes in airway responsiveness and inflammation of rat lung

(2010) Ya-Hong Chen et al.   CYTOKINE

The transwall gradient across the mouse colonic circular muscle layer is carbon monoxide dependent

(2010) L. Sha et al.   FASEB JOURNAL

Endogenous hydrogen sulfide as a mediator of vas deferens smooth muscle relaxation

(2010) Jingxin Li et al.   FERTILITY AND STERILITY

Ramipril Affects Hydrogen Sulfide Generation in Mouse Liver and Kidney

(2010) Bogdan Wiliński et al.   FOLIA BIOLOGICA-KRAKOW

Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest

(2010) Sebastián Carballal et al.   FREE RADICAL BIOLOGY AND MEDICINE

Volatile Sulfur Compounds as a Predictor for Esophagogastroduodenal Mucosal Injury

(2010) Seung Hee Yoo et al.   Gut and Liver

Cystathionine β-synthase mutations: effect of mutation topology on folding and activity

(2010) Viktor Kožich et al.   HUMAN MUTATION

Suspended animation inducer hydrogen sulfide is protective in an in vivo model of ventilator-induced lung injury

(2010) Hamid Aslami et al.   INTENSIVE CARE MEDICINE

Hydrogen Sulfide

(2010) Tee L. Guidotti   INTERNATIONAL JOURNAL OF TOXICOLOGY

Ischemia/Reperfusion Reduces Transcription Factor Sp1-mediated Cystathionine β-Synthase Expression in the Kidney

(2010) Nan Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cystathionine γ-Lyase-deficient Mice Require Dietary Cysteine to Protect against Acute Lethal Myopathy and Oxidative Injury

(2010) Isao Ishii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox Biochemistry of Hydrogen Sulfide

(2010) Omer Kabil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Carbon monoxide stimulates global protein methylation via its inhibitory action on cystathionine β-synthase

(2010) Takehiro Yamamoto et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Determination of cystathionine beta-synthase activity in human plasma by LC-MS/MS: potential use in diagnosis of CBS deficiency

(2010) Jakub Krijt et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Involvement of Src kinase in T-type calcium channel-dependent neuronal differentiation of NG108-15 cells by hydrogen sulfide

(2010) Takeshi Tarui et al.   JOURNAL OF NEUROCHEMISTRY

Oral Malodorous Compound Induces Osteoclast Differentiation Without Receptor Activator of Nuclear Factor κB Ligand

(2010) Hisataka Ii et al.   JOURNAL OF PERIODONTOLOGY

Regulation of erythropoietin production

(2010) Wolfgang Jelkmann   JOURNAL OF PHYSIOLOGY-LONDON

Hydrogen Sulfide Inhibits Plasma Renin Activity

(2010) M. Lu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Curative effects of hydrogen sulfide against acetaminophen-induced hepatotoxicity in mice

(2010) Mohamed A. Morsy et al.   LIFE SCIENCES

Glutathione depletion causes a JNK and p38MAPK-mediated increase in expression of cystathionine-γ-lyase and upregulation of the transsulfuration pathway in C6 glioma cells

(2010) Sarah Kandil et al.   NEUROCHEMISTRY INTERNATIONAL

Hydrogen sulfide reduces mRNA and protein levels of beta-site amyloid precursor protein cleaving enzyme 1 in PC12 cells

(2010) Hua Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Upregulation of Cav3.2 T-type calcium channels targeted by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain

(2010) Tomoko Takahashi et al.   PAIN

Effects of Intravenous Sulfide During Porcine Aortic Occlusion-Induced Kidney Ischemia/Reperfusion Injury

(2010) Florian Simon et al.   SHOCK

Correction

(2010)   TRANSFUSION

4-Aminopyridine-sensitive K+ channels contributes to NaHS-induced membrane hyperpolarization and relaxation in the rat coronary artery

(2010) Wai San Cheang et al.   VASCULAR PHARMACOLOGY

Hydrogen sulfide in cell survival: a double-edged sword

(2010) Guangdong Yang   Expert Review of Clinical Pharmacology

Effects of sulphurous water on human neutrophil elastase release

(2010) Pier Carlo Braga et al.   Therapeutic Advances in Respiratory Disease

Hydrogen sulfide triggers late-phase preconditioning in postischemic small intestine by an NO- and p38 MAPK-dependent mechanism

(2009) Mozow Yusof et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hypoxic pulmonary vasodilation: a paradigm shift with a hydrogen sulfide mechanism

(2009) Kenneth R. Olson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Inhaled Hydrogen Sulfide

(2009) Gian Paolo Volpato et al.   ANESTHESIOLOGY

Molecular Mechanism for H2S-Induced Activation of KATP Channels

(2009) Bo Jiang et al.   ANTIOXIDANTS & REDOX SIGNALING

Physiological and Pathophysiological Roles of Hydrogen Sulfide in the Gastrointestinal Tract

(2009) John L. Wallace   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide: From Brain to Gut

(2009) Hideo Kimura   ANTIOXIDANTS & REDOX SIGNALING

A Crucial Role for Hydrogen Sulfide in Oxygen Sensing via Modulating Large Conductance Calcium-Activated Potassium Channels

(2009) Qian Li et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide and Oxygen Sensing in the Cardiovascular System

(2009) Kenneth R. Olson et al.   ANTIOXIDANTS & REDOX SIGNALING

The Effect of Hydrogen Sulfide Donors on Lipopolysaccharide-Induced Formation of Inflammatory Mediators in Macrophages

(2009) Matthew Whiteman et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide Increases Glutathione Production and Suppresses Oxidative Stress in Mitochondria

(2009) Yuka Kimura et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen sulfide from adipose tissue is a novel insulin resistance regulator

(2009) Xuejuan Feng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hydrogen sulfide is a reversible inhibitor of the NADH oxidase activity of synaptic plasma membranes

(2009) Alejandro K. Samhan-Arias et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cardioprotective Effect of Hydrogen Sulfide in Ischemic Reperfusion Experimental Rats and Its Influence on Expression of Survivin Gene

(2009) Yang Zhuo et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

New prostaglandin derivative for glaucoma treatment

(2009) Elena Perrino et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Actions of hydrogen sulphide on ion transport across rat distal colon

(2009) B Hennig et al.   BRITISH JOURNAL OF PHARMACOLOGY

Beneficial effect of a hydrogen sulphide donor (sodium sulphide) in an ovine model of burn- and smoke-induced acute lung injury

(2009) Aimalohi Esechie et al.   BRITISH JOURNAL OF PHARMACOLOGY

Detection of exhaled hydrogen sulphide gas in rats exposed to intravenous sodium sulphide

(2009) Michael A Insko et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling

(2009) John W. Calvert et al.   CIRCULATION RESEARCH

Transcriptional Repression and Inhibition of Nuclear Translocation of Androgen Receptor by Diallyl Trisulfide in Human Prostate Cancer Cells

(2009) S. D. Stan et al.   CLINICAL CANCER RESEARCH

EDHF: an update

(2009) Michel Félétou et al.   CLINICAL SCIENCE

Hydrogen sulphide synthesis in the rat and mouse gastrointestinal tract

(2009) Gary R. Martin et al.   DIGESTIVE AND LIVER DISEASE

Myosin light chain phosphatase activation is involved in the hydrogen sulfide-induced relaxation in mouse gastric fundus

(2009) Ingeborg Dhaese et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mechanisms of action of hydrogen sulfide in relaxation of mouse distal colonic smooth muscle

(2009) Ingeborg Dhaese et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Endogenous Hydrogen Sulfide Regulates Pulmonary Artery Collagen Remodeling in Rats with High Pulmonary Blood Flow

(2009) Xiaohui Li et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Endogenous and Exogenous Hydrogen Sulfide Promotes Resolution of Colitis in Rats

(2009) John L. Wallace et al.   GASTROENTEROLOGY

H2S and HS– donor NaHS inhibits intracellular chloride channels

(2009) L. Malekova et al.   GENERAL PHYSIOLOGY AND BIOPHYSICS

Increasing the number of diagnostic mutations in malignant hyperthermia

(2009) Soledad Levano et al.   HUMAN MUTATION

Bone tissue and hyperhomocysteinemia

(2009) Régis Levasseur   JOINT BONE SPINE

Vascular Endothelium Expresses 3-Mercaptopyruvate Sulfurtransferase and Produces Hydrogen Sulfide

(2009) N. Shibuya et al.   JOURNAL OF BIOCHEMISTRY

Hydrogen sulfide and the vasculature: a novel vasculoprotective entity and regulator of nitric oxide bioavailability?

(2009) Matthew Whiteman et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Phonons Created in Superfluid Helium by a Thin Film Gold Heater

(2009) I. N. Adamenko et al.   JOURNAL OF LOW TEMPERATURE PHYSICS

Production and Actions of Hydrogen Sulfide, a Novel Gaseous Bioactive Substance, in the Kidneys

(2009) M. Xia et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Expression, Localization, and Pharmacological Role of Kv7 Potassium Channels in Skeletal Muscle Proliferation, Differentiation, and Survival after Myotoxic Insults

(2009) F. A. Iannotti et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

ORIGINAL RESEARCH—BASIC SCIENCE: Initial Characterization of Hydrogen Sulfide Effects in Female Sexual Function

(2009) Balasubramanian Srilatha et al.   Journal of Sexual Medicine

Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a

(2009) Stefanie Slezak et al.   Journal of Translational Medicine

Hydrogen sulfide: a new EDRF

(2009) Rui Wang   KIDNEY INTERNATIONAL

Role of hydrogen sulfide in hepatic ischemia-reperfusion-induced injury in rats

(2009) Kai Kang et al.   LIVER TRANSPLANTATION

Hydrogen Sulfide Increases Hypoxia-inducible Factor-1 Activity Independently of von Hippel–Lindau Tumor Suppressor-1 in C. elegans

(2009) Mark W. Budde et al.   MOLECULAR BIOLOGY OF THE CELL

Cystathionine γ-lyase: Clinical, metabolic, genetic, and structural studies

(2009) Jan P. Kraus et al.   MOLECULAR GENETICS AND METABOLISM

Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalopathy

(2009) Valeria Tiranti et al.   NATURE MEDICINE

Antimicrobial mechanisms of phagocytes and bacterial evasion strategies

(2009) Ronald S. Flannagan et al.   NATURE REVIEWS MICROBIOLOGY

Hydrogen sulphide-generating pathways in haemodialysis patients: a study on relevant metabolites and transcriptional regulation of genes encoding for key enzymes

(2009) A. F. Perna et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Hydrogen sulfide: A novel signaling molecule in the central nervous system

(2009) Boon Hian Tan et al.   NEUROCHEMISTRY INTERNATIONAL

Hydrogen sulfide regulates intracellular pH in rat primary cultured glia cells

(2009) Ming Lu et al.   NEUROSCIENCE RESEARCH

Hyperalgesia induced by spinal and peripheral hydrogen sulfide: Evidence for involvement of Cav3.2 T-type calcium channels

(2009) Yumi Maeda et al.   PAIN

Hydrogen sulfide increases calcium-activated potassium (BK) channel activity of rat pituitary tumor cells

(2009) Guzel F. Sitdikova et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Using a functional enzyme model to understand the chemistry behind hydrogen sulfide induced hibernation

(2009) James P. Collman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6

(2009) A. Gibbs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen sulfide is an endogenous stimulator of angiogenesis

(2009) A. Papapetropoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation

(2009) R. d'Emmanuele di Villa Bianca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

No facilitator required for membrane transport of hydrogen sulfide

(2009) J. C. Mathai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen sulfide suppresses migration, proliferation and myofibroblast transdifferentiation of human lung fibroblasts

(2009) Li-Ping Fang et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

The endogenous production of hydrogen sulphide in intrauterine tissues

(2009) Pushpa Patel et al.   Reproductive Biology and Endocrinology

Comparison of the metabolic and ventilatory response to hypoxia and H2S in unsedated mice and rats

(2009) Philippe Haouzi et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Testosterone Might Cause Relaxation of Human Corpus Cavernosum by Potassium Channel Opening Action

(2009) Oguzhan Yildiz et al.   UROLOGY

Bile-acid-activated farnesoid X receptor regulates hydrogen sulfide production and hepatic microcirculation

(2009) Barbara Renga et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Surviving Blood Loss Using Hydrogen Sulfide

(2009) Michael L. Morrison et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Vasoconstrictive effect of hydrogen sulfide involves downregulation of cAMP in vascular smooth muscle cells

(2008) Jia Jia Lim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

H2S contributes to the hepatic arterial buffer response and mediates vasorelaxation of the hepatic artery via activation of KATP channels

(2008) Nikolai Siebert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signaling

(2008) Saurabh Jha et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Endogenous hydrogen sulphide mediates the cardioprotection induced by ischemic postconditioning

(2008) Qian Chen Yong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Leukocyte trafficking and pain behavioral responses to a hydrogen sulfide donor in acute monoarthritis

(2008) Benjamin Andruski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Hydrogen sulfide as an oxygen sensor in trout gill chemoreceptors

(2008) Kenneth R. Olson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Whole tissue hydrogen sulfide concentrations are orders of magnitude lower than presently accepted values

(2008) Julie Furne et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

3-Mercaptopyruvate Sulfurtransferase Produces Hydrogen Sulfide and Bound Sulfane Sulfur in the Brain

(2008) Norihiro Shibuya et al.   ANTIOXIDANTS & REDOX SIGNALING

Skeletal muscle Kv7 (KCNQ) channels in myoblast differentiation and proliferation

(2008) Meritxell Roura-Ferrer et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Biosynthesis of H2S is impaired in non-obese diabetic (NOD) mice

(2008) V Brancaleone et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hydrogen sulphide is an inhibitor of L-type calcium channels and mechanical contraction in rat cardiomyocytes

(2008) Ying-Gang Sun et al.   CARDIOVASCULAR RESEARCH

Protective effect of hydrogen sulfide in a murine model of acute lung injury induced by combined burn and smoke inhalation

(2008) Aimalohi Esechie et al.   CLINICAL SCIENCE

Biological rhythms: Clocks for all times

(2008) Albert Goldbeter   CURRENT BIOLOGY

Exogenous hydrogen sulfide postconditioning protects isolated rat hearts against ischemia-reperfusion injury

(2008) Yong Ji et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hydrogen Sulphide Is Involved in Testosterone Vascular Effect

(2008) Mariarosaria Bucci et al.   EUROPEAN UROLOGY

Transient Receptor Potential A1 (TRPA1) Activity in the Human Urethra—Evidence for a Functional Role for TRPA1 in the Outflow Region

(2008) Christian Gratzke et al.   EUROPEAN UROLOGY

Regulatory Effects of Hydrogen Sulfide on IL-6, IL-8 and IL-10 Levels in the Plasma and Pulmonary Tissue of Rats with Acute Lung Injury

(2008) Tianshui Li et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Mouse models of cystathionine β-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia

(2008) Sapna Gupta et al.   FASEB JOURNAL

Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria

(2008) Tatjana M. Hildebrandt et al.   FEBS Journal

Glucose-induced production of hydrogen sulfide may protect the pancreatic beta-cells from apoptotic cell death by high glucose

(2008) Yukiko Kaneko et al.   FEBS LETTERS

Hydrogen sulfide protects astrocytes against H2O2-induced neural injury via enhancing glutamate uptake

(2008) Ming Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetic background conversion ameliorates semi-lethality and permits behavioral analyses in cystathionine β-synthase-deficient mice, an animal model for hyperhomocysteinemia

(2008) Noriyuki Akahoshi et al.   HUMAN MOLECULAR GENETICS

The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance

(2008) Chris E. Cooper et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Active Cystathionine β-Synthase Can Be Expressed in Heme-free Systems in the Presence of Metal-substituted Porphyrins or a Chemical Chaperone

(2008) Tomas Majtan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for the Inhibition Mechanism of Human Cystathionine γ-Lyase, an Enzyme Responsible for the Production of H2S

(2008) Qingxiang Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Levcromakalim and MgGDP Activate Small Conductance ATP-Sensitive K+ Channels of K+ Channel Pore 6.1/Sulfonylurea Receptor 2A in Pig Detrusor Smooth Muscle Cells: Uncoupling of cAMP Signal Pathways

(2008) S. Kajioka et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats

(2008) Lingyun Wu et al.   LABORATORY INVESTIGATION

Hydrogen sulfide decreases adenosine triphosphate levels in aortic rings and leads to vasorelaxation via metabolic inhibition

(2008) Levente Kiss et al.   LIFE SCIENCES

Endogenous hydrogen sulfide is involved in regulation of respiration in medullary slice of neonatal rats

(2008) H. Hu et al.   NEUROSCIENCE

Prostaglandins, NSAIDs, and Gastric Mucosal Protection: Why Doesn't the Stomach Digest Itself?

(2008) John L. Wallace   PHYSIOLOGICAL REVIEWS

Human Polycomb 2 Protein Is a SUMO E3 Ligase and Alleviates Substrate-Induced Inhibition of Cystathionine β-Synthase Sumoylation

(2008) Nitish Agrawal et al.   PLoS One

H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine  -Lyase

(2008) G. Yang et al.   SCIENCE

HEMODYNAMIC AND METABOLIC EFFECTS OF HYDROGEN SULFIDE DURING PORCINE ISCHEMIA/REPERFUSION INJURY

(2008) Florian Simon et al.   SHOCK

Gene Expression Changes Following Acute Hydrogen Sulfide (H2S)-induced Nasal Respiratory Epithelial Injury

(2008) E. S. Roberts et al.   TOXICOLOGIC PATHOLOGY

Putative biological roles of hydrogen sulfide in health and disease: a breath of not so fresh air?

(2008) L LI et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Editorial Comment on: Distribution and Function of the Hydrogen Sulfide–Sensitive TRPA1 Ion Channel in Rat Urinary Bladder

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