Gas what: NO is not the only answer to sexual function

Hydrogen sulfide in the mouse ductus arteriosus: a naturally occurring relaxant with potential EDHF function

(2013) Barbara Baragatti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Heme Oxygenase-1 As a Target for Drug Discovery

(2013) Roberto Motterlini et al.   ANTIOXIDANTS & REDOX SIGNALING

Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats

(2013) Wen Yu et al.   ASIAN JOURNAL OF ANDROLOGY

How I manage priapism due to sickle cell disease

(2013) Ade Olujohungbe et al.   BRITISH JOURNAL OF HAEMATOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Enzymes

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Ion Channels

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Oral l‐Citrulline Supplementation Improves Erectile Function in Rats with Acute Arteriogenic Erectile Dysfunction

(2013) Arufumi Shiota et al.   Journal of Sexual Medicine

Nitric Oxide‐Releasing Polymeric Microspheres Improve Diabetes‐Related Erectile Dysfunction

(2013) Samit D. Soni et al.   Journal of Sexual Medicine

Superoxide Anion Production by NADPH Oxidase Plays a Major Role in Erectile Dysfunction in Middle‐Aged Rats: Prevention by Antioxidant Therapy

(2013) Fábio H. Silva et al.   Journal of Sexual Medicine

An Oral Formulation of Angiotensin‐(1‐7) Reverses Corpus Cavernosum Damages Induced by Hypercholesterolemia

(2013) Rodrigo A. Fraga‐Silva et al.   Journal of Sexual Medicine

Metformin Treatment Improves Erectile Function in an Angiotensin II Model of Erectile Dysfunction

(2013) Hicham Labazi et al.   Journal of Sexual Medicine

saRNA Guided iNOS Up-Regulation Improves Erectile Function of Diabetic Rats

(2013) Tao Wang et al.   JOURNAL OF UROLOGY

Hydrogen sulfide protects endothelial nitric oxide function under conditions of acute oxidative stress in vitro.

(2013) Mohammad R. Al-Magableh et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Modulation of Soluble Guanylate Cyclase for the Treatment of Erectile Dysfunction

(2013) George F. Lasker et al.   PHYSIOLOGY

Sildenafil Citrate-Restored eNOS and PDE5 Regulation in Sickle Cell Mouse Penis Prevents Priapism Via Control of Oxidative/Nitrosative Stress

(2013) Trinity J. Bivalacqua et al.   PLoS One

Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia

(2013) R. d'Emmanuele di Villa Bianca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Second Pathways in the Pathophysiology of Ischemic Priapism and Treatment Alternatives

(2013) Ahmet Karakeci et al.   UROLOGY

S-allyl cysteine restores erectile function through inhibition of reactive oxygen species generation in diabetic rats

(2013) J. Yang et al.   Andrology

Bioassay-comparison of the antioxidant efficacy of hydrogen sulfide and superoxide dismutase in isolated arteries and veins

(2012) J. Hamar et al.   ACTA PHYSIOLOGICA HUNGARICA

Endogenous hydrogen sulfide insufficiency as a predictor of sexual dysfunction in aging rats

(2012) Balasubramanian Srilatha et al.   Aging Male

Sildenafil stimulates the expression of gaseous monoxide-generating enzymes in vascular smooth muscle cells via distinct signaling pathways

(2012) Xiao-ming Liu et al.   BIOCHEMICAL PHARMACOLOGY

Distribution of H2S Synthesis Enzymes in the Walls of Cerebral Arteries in Rats

(2012) V. M. Chertok et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Sildenafil Effect on the Human Bladder Involves the L-cysteine/Hydrogen Sulfide Pathway: A Novel Mechanism of Action of Phosphodiesterase Type 5 Inhibitors

(2012) Ferdinando Fusco et al.   EUROPEAN UROLOGY

cGMP-Dependent Activation of Protein Kinase G Precludes Disulfide Activation

(2012) Joseph Robert Burgoyne et al.   HYPERTENSION

Hydrogen sulfide promotes nitric oxide production in corpus cavernosum by enhancing expression of endothelial nitric oxide synthase

(2012) J Meng et al.   INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH

Chronic Oral Administration of the Arginase Inhibitor 2(S)-amino-6-boronohexanoic Acid (ABH) Improves Erectile Function in Aged Rats

(2012) R. Segal et al.   JOURNAL OF ANDROLOGY

Divergent Molecular Mechanisms Underlay CO‐ and CORM‐2‐Induced Relaxation of Corpora Cavernosa

(2012) Kelly Decaluwé et al.   Journal of Sexual Medicine

Apocynin Improves Erectile Function in Diabetic Rats through Regulation of NADPH Oxidase Expression

(2012) Mingchao Li et al.   Journal of Sexual Medicine

Effects of Low‐Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

(2012) Xuefeng Qiu et al.   Journal of Sexual Medicine

S-Nitrosylation of endothelial nitric oxide synthase alters erectile function

(2012) Lisa Palmer et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydroxyfasudil ameliorates penile dysfunction in the male spontaneously hypertensive rat

(2012) Motoaki Saito et al.   PHARMACOLOGICAL RESEARCH

Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed

(2012) Rui Wang   PHYSIOLOGICAL REVIEWS

Endogenous Urotensin II Selectively Modulates Erectile Function through eNOS

(2012) Roberta d'Emmanuele di Villa Bianca et al.   PLoS One

Role of Neural NO Synthase (nNOS) Uncoupling in the Dysfunctional Nitrergic Vasorelaxation of Penile Arteries from Insulin-Resistant Obese Zucker Rats

(2012) Ana Sánchez et al.   PLoS One

cGMP-Dependent Protein Kinase Contributes to Hydrogen Sulfide-Stimulated Vasorelaxation

(2012) Mariarosaria Bucci et al.   PLoS One

Soluble guanylyl cyclase requires heat shock protein 90 for heme insertion during maturation of the NO-active enzyme

(2012) A. Ghosh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway

(2012) T. Morikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclic AMP-dependent phosphorylation of neuronal nitric oxide synthase mediates penile erection

(2012) K. J. Hurt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation

(2012) C. Coletta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A randomized, double-blind, crossover, placebo-controlled comparative clinical trial of arginine aspartate plus adenosine monophosphate for the intermittent treatment of male erectile dysfunction

(2012) Y. Neuzillet et al.   Andrology

Androgen depletion in humans leads to cavernous tissue reorganization and upregulation of Sirt1–eNOS axis

(2011) Inês Tomada et al.   AGE

Association of lower total bilirubin level with statin usage: The United States National Health and Nutrition Examination Survey 1999–2008

(2011) Kwok Leung Ong et al.   ATHEROSCLEROSIS

Caveolin-1 Is a Competitive Inhibitor of Heme Oxygenase-1 (HO-1) with Heme: Identification of a Minimum Sequence in Caveolin-1 for Binding to HO-1

(2011) Junichi Taira et al.   BIOCHEMISTRY

Hydrogen Sulfide as Endothelium-Derived Hyperpolarizing Factor Sulfhydrates Potassium Channels

(2011) Asif K. Mustafa et al.   CIRCULATION RESEARCH

Cysteine and obesity

(2011) Amany K. Elshorbagy et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Divergent mechanisms involved in CO and CORM-2 induced vasorelaxation

(2011) Kelly Decaluwé et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Application of nitric oxide in drug discovery and development

(2011) Nathan S Bryan   Expert Opinion on Drug Discovery

eNOS-uncoupling in age-related erectile dysfunction

(2011) J M Johnson et al.   INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH

Pharmacokinetics of the Soluble Guanylate Cyclase Activator Cinaciguat in Individuals With Hepatic Impairment

(2011) Reiner Frey et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Vardenafil and Resveratrol Synergistically Enhance the Nitric Oxide/Cyclic Guanosine Monophosphate Pathway in Corpus Cavernosal Smooth Muscle Cells and Its Therapeutic Potential for Erectile Dysfunction in the Streptozotocin‐Induced Diabetic Rat: Preliminary Findings

(2011) Shinichiro Fukuhara et al.   Journal of Sexual Medicine

Hydrogen sulfide and erectile function: a novel therapeutic target

(2011) Roberta d'Emmanuele di Villa Bianca et al.   Nature Reviews Urology

Hydrogen Sulfide Attenuated Tumor Necrosis Factor-α-Induced Inflammatory Signaling and Dysfunction in Vascular Endothelial Cells

(2011) Li-Long Pan et al.   PLoS One

Statin Attenuates Experimental Anti-Glomerular Basement Membrane Glomerulonephritis Together with the Augmentation of Alternatively Activated Macrophages

(2010) Emiko Fujita et al.   AMERICAN JOURNAL OF PATHOLOGY

Hydrogen sulfide protects against vascular remodeling from endothelial damage

(2010) Thomas P. Vacek et al.   AMINO ACIDS

Hydrogen Sulfide Is an Endogenous Inhibitor of Phosphodiesterase Activity

(2010) Mariarosaria Bucci et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

SIRT1 regulates oxidant- and cigarette smoke-induced eNOS acetylation in endothelial cells: Role of resveratrol

(2010) Gnanapragasam Arunachalam et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hydrogen sulphide induces mouse paw oedema through activation of phospholipase A2

(2010) Roberta d'Emmanuele di Villa Bianca et al.   BRITISH JOURNAL OF PHARMACOLOGY

Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncoupling

(2010) Ulrich Förstermann et al.   BRITISH JOURNAL OF PHARMACOLOGY

Intracavernosal administration of sodium nitrite as an erectile pharmacotherapy

(2010) George F. Lasker et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Erectile Dysfunction

(2010) David Shin et al.   Cardiology in Review

Nitric Oxide–Dependent Bone Marrow Progenitor Mobilization by Carbon Monoxide Enhances Endothelial Repair After Vascular Injury

(2010) Barbara Wegiel et al.   CIRCULATION

S -Nitrosylation in Cardiovascular Signaling

(2010) Brian Lima et al.   CIRCULATION RESEARCH

Changes in caveolin-1 expression and vasoreactivity in the aorta and corpus cavernosum of fructose and streptozotocin-induced diabetic rats

(2010) Kübra H. Elçioğlu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Evaluation of vascular smooth muscle and corpus cavernosum on hypercholesterolemia. Is resveratrol promising on erectile dysfunction?

(2010) B C Soner et al.   INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH

Carbon Monoxide Promotes VEGF Expression by Increasing HIF-1α Protein Level via Two Distinct Mechanisms, Translational Activation and Stabilization of HIF-1α Protein

(2010) Yoon Kyung Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heme-Dependent and Independent Soluble Guanylate Cyclase Activators and Vasodilation

(2010) Fernanda B M Priviero et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Hydrogen sulfide as a gasotransmitter

(2010) Moataz M. Gadalla et al.   JOURNAL OF NEUROCHEMISTRY

ORIGINAL RESEARCH—BASIC SCIENCE: Effect of Hemin and Carbon Monoxide Releasing Molecule (CORM-3) on cGMP in Rat Penile Tissue

(2010) M. Talaat Abdel Aziz et al.   Journal of Sexual Medicine

Hypercholesterolemia-Induced Erectile Dysfunction: Endothelial Nitric Oxide Synthase (eNOS) Uncoupling in the Mouse Penis by NAD(P)H Oxidase

(2010) Biljana Musicki et al.   Journal of Sexual Medicine

Post‐Translational Inactivation of Endothelial Nitric Oxide Synthase in the Transgenic Sickle Cell Mouse Penis

(2010) Biljana Musicki et al.   Journal of Sexual Medicine

Arginase II Deletion Increases Corpora Cavernosa Relaxation in Diabetic Mice

(2010) Haroldo A. Toque et al.   Journal of Sexual Medicine

The therapeutic potential of carbon monoxide

(2010) Roberto Motterlini et al.   NATURE REVIEWS DRUG DISCOVERY

Acute Effects of Hypercholesterolemic Diet on Erectile Responses in Rats

(2010) Omer Demir et al.   UROLOGIA INTERNATIONALIS

Effect of HO-1 cDNA-liposome complex transfer on erectile signalling of aged rats

(2009) M. T. Abdel Aziz et al.   ANDROLOGIA

Molecular Mechanism for H2S-Induced Activation of KATP Channels

(2009) Bo Jiang et al.   ANTIOXIDANTS & REDOX SIGNALING

Effect of hydrogen sulphide-donating sildenafil (ACS6) on erectile function and oxidative stress in rabbit isolated corpus cavernosum and in hypertensive rats

(2009) Nilima Shukla et al.   BJU INTERNATIONAL

Chronic inhibition of nitric-oxide synthase induces hypertension and erectile dysfunction in the rat that is not reversed by sildenafil

(2009) Serap Gur et al.   BJU INTERNATIONAL

Phosphodiesterase-5 Inhibitor, Tadalafil, Protects Against Myocardial Ischemia/Reperfusion Through Protein-Kinase G-Dependent Generation of Hydrogen Sulfide

(2009) F. N. Salloum et al.   CIRCULATION

EDHF: an update

(2009) Michel Félétou et al.   CLINICAL SCIENCE

Effect of propionyl-l-carnitine,l-arginine and nicotinic acid on the efficacy of vardenafil in the treatment of erectile dysfunction in diabetes

(2009) Vincenzo Gentile et al.   CURRENT MEDICAL RESEARCH AND OPINION

Hemin, a carbon monoxide donor, improves systemic vascular compliance by inhibiting the RhoA–Rhokinase pathway in spontaneous hypertensive rats

(2009) Bonaventure Awede et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dimethylarginine dimethylaminohydrolase in rat penile tissue: reduced enzyme activity is responsible for erectile dysfunction in a rat model of atherosclerosis

(2009) K Park et al.   INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH

Posttranslational Modification of Constitutive Nitric Oxide Synthase in the Penis

(2009) B. Musicki et al.   JOURNAL OF ANDROLOGY

Expression of Caveolin-1 in Penile Cavernosal Tissue in a Denervated Animal Model after Treatment with Sildenafil Citrate

(2009) Edgardo F. Becher et al.   Journal of Sexual Medicine

REVIEWS: The Potential Role of the Heme Oxygenase/Carbon Monoxide System in Male Sexual Dysfunctions

(2009) Rany Shamloul   Journal of Sexual Medicine

Increased Cavernosal Relaxations in Sickle Cell Mice Priapism are Associated with Alterations in the NO-cGMP Signaling Pathway

(2009) Mário Angelo Claudino et al.   Journal of Sexual Medicine

Putative Role of Carbon Monoxide Signaling Pathway in Penile Erectile Function

(2009) Mohamed T. Abdel Aziz et al.   Journal of Sexual Medicine

Effects of Losartan, HO‐1 Inducers or HO‐1 Inhibitors on Erectile Signaling in Diabetic Rats

(2009) Mohamed Talaat Abdel Aziz et al.   Journal of Sexual Medicine

Novel Water-soluble Curcumin Derivative Mediating Erectile Signaling

(2009) Mohamed Talaat Abdel Aziz et al.   Journal of Sexual Medicine

Hydrogen sulfide: a new EDRF

(2009) Rui Wang   KIDNEY INTERNATIONAL

Molecular mechanisms regulating urogenital expression of nitric oxide synthase in spontaneously hypertensive rats

(2009) Makoto Yono et al.   LIFE SCIENCES

Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation

(2009) R. d'Emmanuele di Villa Bianca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H2S Signals Through Protein S-Sulfhydration

(2009) A. K. Mustafa et al.   Science Signaling

Testosterone Might Cause Relaxation of Human Corpus Cavernosum by Potassium Channel Opening Action

(2009) Oguzhan Yildiz et al.   UROLOGY

trans-resveratrol relaxes the corpus cavernosum ex vivo and enhances testosterone levels and sperm quality in vivo

(2008) Sunhee Shin et al.   ARCHIVES OF PHARMACAL RESEARCH

Is H 2 S a Stinky Remedy for Atherosclerosis?

(2008) Rui Wang   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of Hydrogen Sulfide in the Development of Atherosclerotic Lesions in Apolipoprotein E Knockout Mice

(2008) Yanfei Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

NADPH oxidase: recent evidence for its role in erectile dysfunction

(2008) Liming Jin et al.   ASIAN JOURNAL OF ANDROLOGY

Impaired nerve-mediated relaxation of penile tissue from caveolin-1 deficient mice

(2008) Yulia Shakirova et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hydrogen Sulphide Is Involved in Testosterone Vascular Effect

(2008) Mariarosaria Bucci et al.   EUROPEAN UROLOGY

Antioxidant Treatment with .ALPHA.-Tocopherol Improves Erectile Function in Hypertensive Rats

(2008) Masayuki USHIYAMA et al.   HYPERTENSION RESEARCH

Evolution of Novel Small-Molecule Therapeutics Targeting Sickle Cell Vasculopathy

(2008) Gregory J. Kato   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Expression and Activity of Heme Oxygenase‐1 in Artificially Induced Low‐Flow Priapism in Rat Penile Tissues

(2008) Yong Chun Jin et al.   Journal of Sexual Medicine

Low-Fat Diet and Exercise Preserve eNOS Regulation and Endothelial Function in the Penis of Early Atherosclerotic Pigs: A Molecular Analysis

(2008) Biljana Musicki et al.   Journal of Sexual Medicine

NADPH Oxidase Activation: A Mechanism of Hypertension-Associated Erectile Dysfunction

(2008) Liming Jin et al.   Journal of Sexual Medicine

Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats

(2008) Lingyun Wu et al.   LABORATORY INVESTIGATION

Perspective on Recent Developments on Sulfur-Containing Agents and Hydrogen Sulfide Signaling

(2008) Claus Jacob et al.   PLANTA MEDICA

H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine  -Lyase

(2008) G. Yang et al.   SCIENCE