Epithelial Electrolyte Transport Physiology and the Gasotransmitter Hydrogen Sulfide

The H2S-generating enzymes cystathionine β-synthase and cystathionine γ-lyase play a role in vascular development during normal lung alveolarization

(2015) Alicia Madurga et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Hydrogen sulfide decreases β-adrenergic agonist-stimulated lung liquid clearance by inhibiting ENaC-mediated transepithelial sodium absorption

(2015) Alisa M. Agné et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Hydrogen Sulfide as an Oxygen Sensor

(2015) Kenneth R. Olson   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide Protects from Colitis and Restores Intestinal Microbiota Biofilm and Mucus Production

(2015) Jean-Paul Motta et al.   INFLAMMATORY BOWEL DISEASES

Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter

(2015) John L. Wallace et al.   NATURE REVIEWS DRUG DISCOVERY

Hydrogen Sulfide Prevents Advanced Glycation End-Products Induced Activation of the Epithelial Sodium Channel

(2015) Qiushi Wang et al.   Oxidative Medicine and Cellular Longevity

Epithelial Sodium Transport and Its Control by Aldosterone: The Story of Our Internal Environment Revisited

(2015) Bernard C. Rossier et al.   PHYSIOLOGICAL REVIEWS

Airway Gland Structure and Function

(2015) Jonathan H. Widdicombe et al.   PHYSIOLOGICAL REVIEWS

H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO–TRPA1–CGRP signalling pathway

(2015) Mirjam Eberhardt et al.   Nature Communications

Endogenous Production of Hydrogen Sulfide in Human Sinus Mucosa and its Expression Levels are Altered in Patients with Chronic Rhinosinusitis with and without Nasal Polyps

(2014) Jae Woong Hwang et al.   American Journal of Rhinology & Allergy

Hydrogen Sulfide Targets EGFR Cys797/Cys798 Residues to Induce Na+/K+-ATPase Endocytosis and Inhibition in Renal Tubular Epithelial Cells and Increase Sodium Excretion in Chronic Salt-Loaded Rats

(2014) Shun-Na Ge et al.   ANTIOXIDANTS & REDOX SIGNALING

NSAID-gastroenteropathy: new aspects of pathogenesis and prevention

(2014) Rory W Blackler et al.   CURRENT OPINION IN PHARMACOLOGY

α-ENaC, a therapeutic target of dexamethasone on hydrogen sulfide induced acute pulmonary edema

(2014) Lei Jiang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Understanding Hydrogen Sulfide Storage: Probing Conditions for Sulfide Release from Hydrodisulfides

(2014) T. Spencer Bailey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrogen Sulfide and Polysulfides as Biological Mediators

(2014) Hideo Kimura   MOLECULES

Controversies and conundrums in hydrogen sulfide biology

(2014) Kenneth R. Olson et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydrogen sulfide inhibits Na+ uptake in larval zebrafish, Danio rerio

(2014) Yusuke Kumai et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Actions of Hydrogen Sulfide on Sodium Transport Processes across Native Distal Lung Epithelia (Xenopus laevis)

(2014) Alexandra Erb et al.   PLoS One

Dexamethasone Ameliorates H2S-Induced Acute Lung Injury by Alleviating Matrix Metalloproteinase-2 and -9 Expression

(2014) Jun Wang et al.   PLoS One

Pseudomonas aeruginosa triggers CFTR-mediated airway surface liquid secretion in swine trachea

(2014) X. Luan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen sulfide donors in research and drug development

(2014) Zhi Jian Song et al.   MedChemComm

Oxygen Sensing by the Carotid Body: Is It All Just Rotten Eggs?

(2013) Paul J. Kemp et al.   ANTIOXIDANTS & REDOX SIGNALING

S-Glutathionylation of Ion Channels: Insights into the Regulation of Channel Functions, Thiol Modification Crosstalk, and Mechanosensing

(2013) Yang Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery

(2013) Candice E. Paulsen et al.   CHEMICAL REVIEWS

Actions of Angeli's salt, a nitroxyl (HNO) donor, on ion transport across mucosa—submucosa preparations from rat distal colon

(2013) Ervice Pouokam et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Expression levels of endogenous hydrogen sulfide are altered in patients with allergic rhinitis

(2013) Se Jin Park et al.   LARYNGOSCOPE

Physiological role of hydrogen sulfide and polysulfide in the central nervous system

(2013) Hideo Kimura   NEUROCHEMISTRY INTERNATIONAL

Hydrogen Sulfide Prevents Hydrogen Peroxide-Induced Activation of Epithelial Sodium Channel through a PTEN/PI(3,4,5)P3 Dependent Pathway

(2013) Jianing Zhang et al.   PLoS One

Hydrogen sulfide: both feet on the gas and none on the brake?

(2013) Kenneth R. Olson   Frontiers in Physiology

ENaC Inhibitors and Airway Re-hydration in Cystic Fibrosis: State of the Art

(2013) Mike Althaus   Current Molecular Pharmacology

Detoxification of H2S by Differentiated Colonic Epithelial Cells: Implication of the Sulfide Oxidizing Unit and of the Cell Respiratory Capacity

(2012) Sabria Mimoun et al.   ANTIOXIDANTS & REDOX SIGNALING

Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras

(2012) Khosrow Kashfi et al.   BIOCHEMICAL PHARMACOLOGY

The gasotransmitter hydrogen sulphide decreases Na+ transport across pulmonary epithelial cells

(2012) M Althaus et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hydrogen sulfide as an oxygen sensor

(2012) Kenneth R. Olson   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Gas Mediators Involved in Modulating Duodenal HCO3- Secretion

(2012) K. Takeuchi et al.   CURRENT MEDICINAL CHEMISTRY

Altered response to hydrogen sulphide during experimental colitis in rats

(2012) J. Steidle et al.   JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION

Subunit Isoform Selectivity in Assembly of Na,K-ATPase α-β Heterodimers

(2012) Elmira Tokhtaeva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATP-sensitive K+ channels in rat colonic epithelium

(2012) Ervice Pouokam et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed

(2012) Rui Wang   PHYSIOLOGICAL REVIEWS

Gasotransmitters: Novel Regulators of Epithelial Na+ Transport?

(2012) Mike Althaus   Frontiers in Physiology

Modulation of ion transport across rat distal colon by cysteine

(2012) Ervice Pouokam   Frontiers in Physiology

Metabolic Turnover of Hydrogen Sulfide

(2012) Hideo Kimura   Frontiers in Physiology

Passive loss of hydrogen sulfide in biological experiments

(2011) Eric R. DeLeon et al.   ANALYTICAL BIOCHEMISTRY

Protective and Detrimental Effects of Sodium Sulfide and Hydrogen Sulfide in Murine Ventilator-induced Lung Injury

(2011) Roland C. Francis et al.   ANESTHESIOLOGY

HNO Signaling Mechanisms

(2011) Jon M. Fukuto et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of Colonic Ion Transport by Gasotransmitters

(2011) Ervice Pouokam et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Hydrogen Sulfide as Endothelium-Derived Hyperpolarizing Factor Sulfhydrates Potassium Channels

(2011) Asif K. Mustafa et al.   CIRCULATION RESEARCH

Regulation and dysregulation of epithelial Na+ channels

(2011) Lawrence G. Palmer et al.   Clinical and Experimental Nephrology

Precursors and inhibitors of hydrogen sulfide synthesis affect acute hypoxic pulmonary vasoconstriction in the intact lung

(2011) Jane A. Madden et al.   JOURNAL OF APPLIED PHYSIOLOGY

Hydrogen sulfide (H2S) and hypoxia inhibit salmonid gastrointestinal motility: evidence for H2S as an oxygen sensor

(2011) R. A. Dombkowski et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

H2S: A Universal Defense Against Antibiotics in Bacteria

(2011) K. Shatalin et al.   SCIENCE

Nitric Oxide Inhibits Highly Selective Sodium Channels and the Na+/K+-ATPase in H441 Cells

(2010) Mike Althaus et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mechanisms of actions of hydrogen sulphide on rat distal colonic epithelium

(2010) E Pouokam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hydrogen Sulfide

(2010) Tee L. Guidotti   INTERNATIONAL JOURNAL OF TOXICOLOGY

Signaling mechanisms involved in the intestinal pro-secretory actions of hydrogen sulfide

(2010) D. Krueger et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Gut Microbiota in Health and Disease

(2010) Inna Sekirov et al.   PHYSIOLOGICAL REVIEWS

Hypoxic pulmonary vasodilation: a paradigm shift with a hydrogen sulfide mechanism

(2009) Kenneth R. Olson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Luminal sulfide and large intestine mucosa: friend or foe?

(2009) François Blachier et al.   AMINO ACIDS

Actions of hydrogen sulphide on ion transport across rat distal colon

(2009) B Hennig et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of endogenous hydrogen sulfide synthesis by PAG protects against ethanol-induced gastric damage in the rat

(2009) Aracely Evangelina Chávez-Piña et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Culture-independent analysis of desulfovibrios in the human distal colon of healthy, colorectal cancer and polypectomized individuals

(2009) Pauline D. Scanlan et al.   FEMS MICROBIOLOGY ECOLOGY

Endogenous and Exogenous Hydrogen Sulfide Promotes Resolution of Colitis in Rats

(2009) John L. Wallace et al.   GASTROENTEROLOGY

Using a functional enzyme model to understand the chemistry behind hydrogen sulfide induced hibernation

(2009) James P. Collman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

No facilitator required for membrane transport of hydrogen sulfide

(2009) J. C. Mathai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H2S Signals Through Protein S-Sulfhydration

(2009) A. K. Mustafa et al.   Science Signaling

Stem Cells, Self-Renewal, and Differentiation in the Intestinal Epithelium

(2008) Laurens G. van der Flier et al.   Annual Review of Physiology

3-Mercaptopyruvate Sulfurtransferase Produces Hydrogen Sulfide and Bound Sulfane Sulfur in the Brain

(2008) Norihiro Shibuya et al.   ANTIOXIDANTS & REDOX SIGNALING

Production of the gaseous signal molecule hydrogen sulfide in mouse tissues

(2008) David R. Linden et al.   JOURNAL OF NEUROCHEMISTRY

Mechanisms of ENaC Regulation and Clinical Implications

(2008) V. Bhalla et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inhibition of Hydrogen Sulfide Synthesis Attenuates Chemokine Production and Protects Mice Against Acute Pancreatitis and Associated Lung Injury

(2008) Ramasamy Tamizhselvi et al.   PANCREAS

Enhanced activity of a hydrogen sulphide-releasing derivative of mesalamine (ATB-429) in a mouse model of colitis

(2007) S Fiorucci et al.   BRITISH JOURNAL OF PHARMACOLOGY