H2S biosynthesis and catabolism: new insights from molecular studies

Hydrogen sulfide depletion contributes to microvascular remodeling in obesity

(2016) Joseph Candela et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hydrogen Sulfide Is an Antiviral and Antiinflammatory Endogenous Gasotransmitter in the Airways. Role in Respiratory Syncytial Virus Infection

(2016) Teodora Ivanciuc et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Decreased Gluconeogenesis in the Absence of Cystathionine Gamma-Lyase and the Underlying Mechanisms

(2016) Ashley A. Untereiner et al.   ANTIOXIDANTS & REDOX SIGNALING

SIRT3 Mediates the Antioxidant Effect of Hydrogen Sulfide in Endothelial Cells

(2016) Liping Xie et al.   ANTIOXIDANTS & REDOX SIGNALING

Novel Angiogenic Activity and Molecular Mechanisms of ZYZ-803, a Slow-Releasing Hydrogen Sulfide–Nitric Oxide Hybrid Molecule

(2016) Qingxun Hu et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide Mitigates Myocardial Infarction via Promotion of Mitochondrial Biogenesis-Dependent M2 Polarization of Macrophages

(2016) Lei Miao et al.   ANTIOXIDANTS & REDOX SIGNALING

Bioenergetic relevance of hydrogen sulfide and the interplay between gasotransmitters at human cystathionine β-synthase

(2016) João B. Vicente et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Cystathionine γ lyase–hydrogen sulfide increases peroxisome proliferator-activated receptor γ activity by sulfhydration at C139 site thereby promoting glucose uptake and lipid storage in adipocytes

(2016) Junyan Cai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Divergent behavior of hydrogen sulfide pools and of the sulfur metabolite lanthionine, a novel uremic toxin, in dialysis patients

(2016) Alessandra F. Perna et al.   BIOCHIMIE

Hydrogen sulfide post-conditioning preserves interfibrillar mitochondria of rat heart during ischemia reperfusion injury

(2016) Shakila A. Banu et al.   CELL STRESS & CHAPERONES

Cystathionine β-synthase regulates endothelial function via protein S-sulfhydration

(2016) Sounik Saha et al.   FASEB JOURNAL

Hydrogen Sulfide and Cellular Redox Homeostasis

(2016) Zhi-Zhong Xie et al.   Oxidative Medicine and Cellular Longevity

Hydrogen Sulfide Improves Vascular Calcification in Rats by Inhibiting Endoplasmic Reticulum Stress

(2016) Rui Yang et al.   Oxidative Medicine and Cellular Longevity

AP39, a Mitochondria-Targeted Hydrogen Sulfide Donor, Supports Cellular Bioenergetics and Protects against Alzheimer’s Disease by Preserving Mitochondrial Function in APP/PS1 Mice and Neurons

(2016) Feng-li Zhao et al.   Oxidative Medicine and Cellular Longevity

Roles for ROS and hydrogen sulfide in the longevity response to germline loss inCaenorhabditis elegans

(2016) Yuehua Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen Sulfide Recruits Macrophage Migration by Integrin β1-Src-FAK/Pyk2-Rac Pathway in Myocardial Infarction

(2016) Lei Miao et al.   Scientific Reports

Exogenous H2S contributes to recovery of ischemic post-conditioning-induced cardioprotection by decrease of ROS level via down-regulation of NF-κB and JAK2-STAT3 pathways in the aging cardiomyocytes

(2016) Lina Li et al.   Cell and Bioscience

Exogenous H2S modulates mitochondrial fusion–fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state

(2016) Aili Sun et al.   Cell and Bioscience

Cystathionine beta synthase modulates senescence of human endothelial cells

(2016) Eva Albertini et al.   Aging-US

The H2S-generating enzymes cystathionine β-synthase and cystathionine γ-lyase play a role in vascular development during normal lung alveolarization

(2015) Alicia Madurga et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

miRNA-30 Family Inhibition Protects Against Cardiac Ischemic Injury by Regulating Cystathionine-γ-Lyase Expression

(2015) Yaqi Shen et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide as an Oxygen Sensor

(2015) Kenneth R. Olson   ANTIOXIDANTS & REDOX SIGNALING

Marine natural products as inhibitors of cystathionine beta-synthase activity

(2015) Megan K. Thorson et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The H 2 S-producing enzyme CSE is dispensable for the processing of inflammatory and neuropathic pain

(2015) Katharina M.J. Syhr et al.   BRAIN RESEARCH

Cystathionine γ-lyase regulates arteriogenesis through NO-dependent monocyte recruitment

(2015) Gopi K. Kolluru et al.   CARDIOVASCULAR RESEARCH

Endogenous Hydrogen Sulfide Production Is Essential for Dietary Restriction Benefits

(2015) Christopher Hine et al.   CELL

Correlation of Lower Concentrations of Hydrogen Sulfide with Activation of Protein Kinase CβII in Uremic Accelerated Atherosclerosis Patients

(2015) Han Li et al.   CHINESE MEDICAL JOURNAL

Estrogen Replacement Therapy in Ovariectomized Nonpregnant Ewes Stimulates Uterine Artery Hydrogen Sulfide Biosynthesis by Selectively Up-Regulating Cystathionine β-Synthase Expression

(2015) Thomas J. Lechuga et al.   ENDOCRINOLOGY

Calorie restriction and methionine restriction in control of endogenous hydrogen sulfide production by the transsulfuration pathway

(2015) Christopher Hine et al.   EXPERIMENTAL GERONTOLOGY

Role of cystathionine β-synthase in human breast Cancer

(2015) Suvajit Sen et al.   FREE RADICAL BIOLOGY AND MEDICINE

The importance of rs1021737 and rs482843 polymorphisms of cystathionine gammalyase in the etiology of preeclampsia in the Caucasian population

(2015) Przemysław Mrozikiewicz et al.   Ginekologia Polska

Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter

(2015) Jiao-Jiao Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial Sulfide Quinone Oxidoreductase Prevents Activation of the Unfolded Protein Response in Hydrogen Sulfide

(2015) Joseph W. Horsman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cysteine and hydrogen sulphide in the regulation of metabolism: insights from genetics and pharmacology

(2015) Roderick N Carter et al.   JOURNAL OF PATHOLOGY

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(2015) Ciro Coletta et al.   MOLECULAR MEDICINE

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(2015) Pauline Snijder et al.   MOLECULAR MEDICINE

Hydrogen sulfide improves glucose metabolism and prevents hypertrophy in cardiomyocytes

(2015) Min Liang et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

H2S-releasing drugs: Anti-inflammatory, cytoprotective and chemopreventative potential

(2015) Burcu Gemici et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydrogen Sulfide Signaling in Oxidative Stress and Aging Development

(2015) Guangdong Yang et al.   Oxidative Medicine and Cellular Longevity

Cardiac H2S Generation Is Reduced in Ageing Diabetic Mice

(2015) Sheng Jin et al.   Oxidative Medicine and Cellular Longevity

Association of the I264T Variant in the Sulfide Quinone Reductase-Like (SQRDL) Gene with Osteoporosis in Korean Postmenopausal Women

(2015) Hyun-Seok Jin et al.   PLoS One

Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl

(2015) Miriam M. Cortese-Krott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Depletion of H2S during obesity enhances store-operated Ca2+entry in adipose tissue macrophages to increase cytokine production

(2015) Gopal V. Velmurugan et al.   Science Signaling

Hemizygosity of transsulfuration genes confers increased vulnerability against acetaminophen-induced hepatotoxicity in mice

(2015) Yoshifumi Hagiya et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

H 2 S: A Novel Gasotransmitter that Signals by Sulfhydration

(2015) Bindu D. Paul et al.   TRENDS IN BIOCHEMICAL SCIENCES

Hydrogen sulphide (H2S) releasing capacity of essential oils isolated from organosulphur rich fruits and vegetables

(2015) Dong Liang et al.   Journal of Functional Foods

Identification of H2S3 and H2S produced by 3-mercaptopyruvate sulfurtransferase in the brain

(2015) Yuka Kimura et al.   Scientific Reports

Depletion of H2S during obesity enhances store-operated Ca2+entry in adipose tissue macrophages to increase cytokine production

(2015) Gopal V. Velmurugan et al.   Science Signaling

The association between the 844ins68 polymorphism in the CBS gene and breast cancer

(2015) Martha Patricia Gallegos-Arreola et al.   Archives of Medical Science

Hydrogen Sulfide Donor Protects Porcine Oocytes against Aging and Improves the Developmental Potential of Aged Porcine Oocytes

(2015) Tereza Krejcova et al.   PLoS One

Role of Hydrogen Sulfide in Early Blood-Brain Barrier Disruption following Transient Focal Cerebral Ischemia

(2015) Zheng Jiang et al.   PLoS One

Study on Environmental Causes and SNPs of MTHFR, MS and CBS Genes Related to Congenital Heart Disease

(2015) Hui Shi et al.   PLoS One

Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate

(2014) Halina Jurkowska et al.   AMINO ACIDS

Sulfur as a Signaling Nutrient Through Hydrogen Sulfide

(2014) Omer Kabil et al.   Annual Review of Nutrition

Activation of AMPK participates hydrogen sulfide-induced cyto-protective effect against dexamethasone in osteoblastic MC3T3-E1 cells

(2014) Ming Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Correlation of Lower Concentrations of Hydrogen Sulfide with Atherosclerosis in Chronic Hemodialysis Patients with Diabetic Nephropathy

(2014) Han Li et al.   BLOOD PURIFICATION

The vertebrate homologue of sulfide-quinone reductase in mammalian mitochondria

(2014) M. Ackermann et al.   CELL AND TISSUE RESEARCH

Hydrogen Sulfide Maintains Mesenchymal Stem Cell Function and Bone Homeostasis via Regulation of Ca2+ Channel Sulfhydration

(2014) Yi Liu et al.   Cell Stem Cell

Endothelial Dysfunction: The Link Between Homocysteine and Hydrogen Sulfide

(2014) Sathnur Pushpakumar et al.   CURRENT MEDICINAL CHEMISTRY

Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: Implications of their possible biological activity and utility

(2014) Katsuhiko Ono et al.   FREE RADICAL BIOLOGY AND MEDICINE

Targeting hydrogen sulfide as a promising therapeutic strategy for atherosclerosis

(2014) Suowen Xu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Effect of Processing Conditions on the Organosulfides of Shallot (Allium cepa L. Aggregatum Group)

(2014) Restituto Tocmo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Organization of the Human Mitochondrial Hydrogen Sulfide Oxidation Pathway

(2014) Marouane Libiad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of MicroRNA29b in Blood–Brain Barrier Dysfunction during Hyperhomocysteinemia: An Epigenetic Mechanism

(2014) Anuradha Kalani et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Hydrogen sulfide treatment induces angiogenesis after cerebral ischemia

(2014) Hyunduk Jang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Involvement of CSE/ H2S in high glucose induced aberrant secretion of adipokines in 3T3-L1 adipocytes

(2014) Zhe Pan et al.   Lipids in Health and Disease

Hydrogen sulfide in plants: From dissipation of excess sulfur to signaling molecule

(2014) Alexander Calderwood et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro

(2014) Bartosz Szczesny et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydrogen sulfide inhibits Na+ uptake in larval zebrafish, Danio rerio

(2014) Yusuke Kumai et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Sodium hydrosulfide inhibits the differentiation of osteoclast progenitor cells via NRF2-dependent mechanism

(2014) Laura Gambari et al.   PHARMACOLOGICAL RESEARCH

Statins upregulate cystathionine γ-lyase transcription and H2S generation via activating Akt signaling in macrophage

(2014) Yuan Xu et al.   PHARMACOLOGICAL RESEARCH

Hydrogen Sulfide Inhibits Formaldehyde-Induced Endoplasmic Reticulum Stress in PC12 Cells by Upregulation of SIRT-1

(2014) Xiang Li et al.   PLoS One

Leptin-Induced Endothelium-Dependent Vasorelaxation of Peripheral Arteries in Lean and Obese Rats: Role of Nitric Oxide and Hydrogen Sulfide

(2014) Anna Jamroz-Wiśniewska et al.   PLoS One

Ethylmalonic Encephalopathy ETHE1 R163W/R163Q Mutations Alter Protein Stability and Redox Properties of the Iron Centre

(2014) Bárbara J. Henriques et al.   PLoS One

Cytoprotective Effects of Hydrogen Sulfide in Novel Rat Models of Non-Erosive Esophagitis

(2014) Oksana Zayachkivska et al.   PLoS One

Anti-Atherogenic Effect of Hydrogen Sulfide by Over-Expression of Cystathionine Gamma-Lyase (CSE) Gene

(2014) Sau Ha Cheung et al.   PLoS One

Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling

(2014) T. Ida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insight into the molecular mechanism of allosteric activation of human cystathionine β-synthase byS-adenosylmethionine

(2014) June Ereño-Orbea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent

(2014) A. L. King et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Hydrogen Sulfide Production by Gene Silencing Attenuates Inflammatory Activity by Downregulation of NF-κB and MAP Kinase Activity in LPS-Activated RAW 264.7 Cells

(2014) Alireza Badiei et al.   Biomed Research International

Nitrosopersulfide (SSNO−) accounts for sustained NO bioactivity of S-nitrosothiols following reaction with sulfide

(2014) Miriam M. Cortese-Krott et al.   Redox Biology

The Inhibitory Role of Hydrogen Sulfide in Airway Hyperresponsiveness and Inflammation in a Mouse Model of Asthma

(2013) Gensheng Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

The effect of CSE gene deletion in caerulein-induced acute pancreatitis in the mouse

(2013) Abel D. Ang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Identification of Cystathionine β-Synthase Inhibitors Using a Hydrogen Sulfide Selective Probe

(2013) Megan K. Thorson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

H2S Is an Endothelium-Derived Hyperpolarizing Factor

(2013) Guanghua Tang et al.   ANTIOXIDANTS & REDOX SIGNALING

The Cysteine Dioxgenase Knockout Mouse: Altered Cysteine Metabolism in Nonhepatic Tissues Leads to Excess H2S/HS− Production and Evidence of Pancreatic and Lung Toxicity

(2013) Heather B. Roman et al.   ANTIOXIDANTS & REDOX SIGNALING

Polysulfides Link H2S to Protein Thiol Oxidation

(2013) Romy Greiner et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide Is an Endogenous Regulator of Aging in Caenorhabditis elegans

(2013) Bedoor Qabazard et al.   ANTIOXIDANTS & REDOX SIGNALING

Enzymology of H2S Biogenesis, Decay and Signaling

(2013) Omer Kabil et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibition of hydrogen sulfide production by gene silencing attenuates inflammatory activity of LPS-activated RAW264.7 cells

(2013) Alireza Badiei et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Cystathionine γ-lyase Accelerates Osteoclast Differentiation

(2013) Takahiro Itou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Oxidative stress suppresses the cellular bioenergetic effect of the 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway

(2013) Katalin Módis et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endogenous hydrogen sulfide protects pancreatic beta-cells from a high-fat diet-induced glucotoxicity and prevents the development of type 2 diabetes

(2013) Mitsuhiro Okamoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proteome adaptations in Ethe1-deficient mice indicate a role in lipid catabolism and cytoskeleton organization via post-translational protein modifications

(2013) Tatjana M. Hildebrandt et al.   BIOSCIENCE REPORTS

Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE)

(2013) Antonia Asimakopoulou et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dysregulation of cystathionine γ-lyase (CSE)/hydrogen sulfide pathway contributes to ox-LDL-induced inflammation in macrophage

(2013) Xian-Hui Wang et al.   CELLULAR SIGNALLING

High-throughput tandem-microwell assay identifies inhibitors of the hydrogen sulfide signaling pathway

(2013) Yueyang Zhou et al.   CHEMICAL COMMUNICATIONS

Dysregulation of Hydrogen Sulfide Producing Enzyme Cystathionine γ-lyase Contributes to Maternal Hypertension and Placental Abnormalities in Preeclampsia

(2013) Keqing Wang et al.   CIRCULATION

H 2 S Protects Against Pressure Overload–Induced Heart Failure via Upregulation of Endothelial Nitric Oxide Synthase

(2013) Kazuhisa Kondo et al.   CIRCULATION

Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis

(2013) Sarathi Mani et al.   CIRCULATION

Structure and Kinetic Analysis of H2S Production by Human Mercaptopyruvate Sulfurtransferase

(2013) Pramod Kumar Yadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cystathionine  -Lyase Protects against Renal Ischemia/Reperfusion by Modulating Oxidative Stress

(2013) E. M. Bos et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

l-Cysteine promotes the proliferation and differentiation of neural stem cells via the CBS/H2S pathway

(2013) Z. Wang et al.   NEUROSCIENCE

Hydrogen sulfide restores a normal morphological phenotype in Werner syndrome fibroblasts, attenuates oxidative damage and modulates mTOR pathway

(2013) F. Talaei et al.   PHARMACOLOGICAL RESEARCH

Effect of the hydrogen sulfide donor GYY4137 on platelet activation and microvascular thrombus formation in mice

(2013) Eberhard Grambow et al.   PLATELETS

Increase or Decrease Hydrogen Sulfide Exert Opposite Lipolysis, but Reduce Global Insulin Resistance in High Fatty Diet Induced Obese Mice

(2013) Bin Geng et al.   PLoS One

Enhanced Synthesis and Diminished Degradation of Hydrogen Sulfide in Experimental Colitis: A Site-Specific, Pro-Resolution Mechanism

(2013) Kyle L. Flannigan et al.   PLoS One

C. elegans Aging Is Modulated by Hydrogen Sulfide and the sulfhydrylase/cysteine Synthase cysl-2

(2013) Bedoor Qabazard et al.   PLoS One

Cystathionine Beta-Synthase (CBS) Contributes to Advanced Ovarian Cancer Progression and Drug Resistance

(2013) Sanjib Bhattacharyya et al.   PLoS One

Tumor-derived hydrogen sulfide, produced by cystathionine- -synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer

(2013) C. Szabo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria

(2013) Noriyuki Nagahara et al.   Scientific Reports

Increased endogenous H2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia

(2012) Utpal Sen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hydrogen Sulfide Protects Against Cellular Senescence via S-Sulfhydration of Keap1 and Activation of Nrf2

(2012) Guangdong Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

Relationship between hydrogen sulfide levels and HDL-cholesterol, adiponectin, and potassium levels in the blood of healthy subjects

(2012) Sushil K. Jain et al.   ATHEROSCLEROSIS

Human Sulfide:Quinone Oxidoreductase Catalyzes the First Step in Hydrogen Sulfide Metabolism and Produces a Sulfane Sulfur Metabolite

(2012) Michael R. Jackson et al.   BIOCHEMISTRY

Hydrogen sulfide-induced inhibition of L-type Ca2+ channels and insulin secretion in mouse pancreatic beta cells

(2012) G. Tang et al.   DIABETOLOGIA

Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics

(2012) Katalin Módis et al.   FASEB JOURNAL

Characterization of Patient Mutations in Human Persulfide Dioxygenase (ETHE1) Involved in H2S Catabolism

(2012) Omer Kabil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Paraoxonase-1 in the Protection of Hydrogen Sulfide-Donating Sildenafil (ACS6) Against Homocysteine-Induced Neurotoxicity

(2012) Xiao-Qing Tang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

p53-Pathway activity and apoptosis in hydrogen sulfide-exposed stem cells separated from human gingival epithelium

(2012) B. Calenic et al.   JOURNAL OF PERIODONTAL RESEARCH

Chemical Characterization of the Smallest S-Nitrosothiol, HSNO; Cellular Cross-talk of H2S and S-Nitrosothiols

(2012) Milos R. Filipovic et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cystathionine β-synthase deficiency causes infertility by impairing decidualization and gene expression networks in uterus implantation sites

(2012) Mario Nuño-Ayala et al.   PHYSIOLOGICAL GENOMICS

Differential Effects of Cystathionine-γ-lyase–Dependent Vasodilatory H2S in Periadventitial Vasoregulation of Rat and Mouse Aortas

(2012) Carolin Köhn et al.   PLoS One

Hydrogen Sulfide Inhibits the Development of Atherosclerosis with Suppressing CX3CR1 and CX3CL1 Expression

(2012) Huili Zhang et al.   PLoS One

NOSH-Aspirin: A Novel Nitric Oxide–Hydrogen Sulfide-Releasing Hybrid: A New Class of Anti-inflammatory Pharmaceuticals

(2012) Ravinder Kodela et al.   ACS Medicinal Chemistry Letters

Knockout of the murine cysteine dioxygenase gene results in severe impairment in ability to synthesize taurine and an increased catabolism of cysteine to hydrogen sulfide

(2011) Iori Ueki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Hydrogen Sulfide and Cell Signaling

(2011) Ling Li et al.   Annual Review of Pharmacology and Toxicology

A Practical Look at the Chemistry and Biology of Hydrogen Sulfide

(2011) Kenneth R. Olson   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen sulfide gas has cell growth regulatory role

(2011) Rajamanickam Baskar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hydrogen sulfide inhibits macrophage-derived foam cell formation

(2011) Zhan-Zhi Zhao et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Measurement of plasma hydrogen sulfide in vivo and in vitro

(2011) Xinggui Shen et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Response ofCaenorhabditis elegansto Hydrogen Sulfide and Hydrogen Cyanide

(2011) Mark W. Budde et al.   GENETICS

The protective role of hydrogen sulfide in myocardial ischemia–reperfusion-induced injury in diabetic rats

(2011) Yan Gao et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Hydrogen Sulfide Inhibits High Glucose-induced Matrix Protein Synthesis by Activating AMP-activated Protein Kinase in Renal Epithelial Cells

(2011) Hak Joo Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen Sulfide Is an Endogenous Potentiator of T Cell Activation

(2011) Thomas W. Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen Sulfide and l-Cysteine Increase Phosphatidylinositol 3,4,5-Trisphosphate (PIP3) and Glucose Utilization by Inhibiting Phosphatase and Tensin Homolog (PTEN) Protein and Activating Phosphoinositide 3-Kinase (PI3K)/Serine/Threonine Protein Kinase (AKT)/Protein Kinase Cζ/λ (PKCζ/λ) in 3T3l1 Adipocytes

(2011) Prasenjit Manna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inducible hydrogen sulfide synthesis in chondrocytes and mesenchymal progenitor cells: is H2S a novel cytoprotective mediator in the inflamed joint?

(2011) Bridget Fox et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Nitrative Stress in Cerebral Endothelium is Mediated by mGluR5 in Hyperhomocysteinemia

(2011) Jamie N Mayo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Increased neointimal formation in cystathionine gamma-lyase deficient mice: Role of hydrogen sulfide in α5β1-integrin and matrix metalloproteinase-2 expression in smooth muscle cells

(2011) Guangdong Yang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The association of Cystathionine β Synthase (CBS) T833C polymorphism and the risk of stroke: A meta-analysis

(2011) Rui Ding et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Hydrogen Sulfide Attenuated Tumor Necrosis Factor-α-Induced Inflammatory Signaling and Dysfunction in Vascular Endothelial Cells

(2011) Li-Long Pan et al.   PLoS One

Hydrogen Sulfide Protects against Chemical Hypoxia-Induced Cytotoxicity and Inflammation in HaCaT Cells through Inhibition of ROS/NF-κB/COX-2 Pathway

(2011) Chuntao Yang et al.   PLoS One

Cystathionine Beta-Synthase Deficiency Causes Fat Loss in Mice

(2011) Sapna Gupta et al.   PLoS One

Increased transsulfuration mediates longevity and dietary restriction in Drosophila

(2011) H. Kabil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen sulfide mediates the anti-survival effect of sulforaphane on human prostate cancer cells

(2011) Yanxi Pei et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cystathionine β-synthase and cystathionine γ-lyase double gene transfer ameliorate homocysteine-mediated mesangial inflammation through hydrogen sulfide generation

(2010) Utpal Sen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Vascular complications of cystathionine β-synthase deficiency: future directions for homocysteine-to-hydrogen sulfide research

(2010) Richard S. Beard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Low Levels of Hydrogen Sulfide in the Blood of Diabetes Patients and Streptozotocin-Treated Rats Causes Vascular Inflammation?

(2010) Sushil K. Jain et al.   ANTIOXIDANTS & REDOX SIGNALING

Chronic Exposure to Sulfide Causes Accelerated Degradation of Cytochrome c Oxidase in Ethylmalonic Encephalopathy

(2010) Ivano Di Meo et al.   ANTIOXIDANTS & REDOX SIGNALING

Endogenous hydrogen sulfide is involved in the pathogenesis of atherosclerosis

(2010) Wang Qiao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes

(2010) Emilie Lagoutte et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells

(2010) Guangdong Yang et al.   CARDIOVASCULAR RESEARCH

Heat shock protein 90 mediates cytoprotection by H2S against chemical hypoxia-induced injury in PC12 cells

(2010) Jin-Lan Meng et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Adiposity is a major determinant of plasma levels of the novel vasodilator hydrogen sulphide

(2010) M. Whiteman et al.   DIABETOLOGIA

Endogenous Hydrogen Sulfide Is an Anti-inflammatory Molecule in Dextran Sodium Sulfate-Induced Colitis in Mice

(2010) Ikuhiro Hirata et al.   DIGESTIVE DISEASES AND SCIENCES

Cystathionine γ-Lyase-deficient Mice Require Dietary Cysteine to Protect against Acute Lethal Myopathy and Oxidative Injury

(2010) Isao Ishii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox Biochemistry of Hydrogen Sulfide

(2010) Omer Kabil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipogenesis Is Decreased by Grape Seed Proanthocyanidins According to Liver Proteomics of Rats Fed a High Fat Diet

(2010) Isabel Baiges et al.   MOLECULAR & CELLULAR PROTEOMICS

A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment

(2010) Kenneth N. Maclean et al.   MOLECULAR GENETICS AND METABOLISM

Cardioprotective effects of hydrogen sulfide

(2010) Gábor Szabó et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Genome-Wide Association Study of Anthropometric Traits and Evidence of Interactions With Age and Study Year in Filipino Women

(2010) Damien C. Croteau-Chonka et al.   Obesity

Upregulation of Cav3.2 T-type calcium channels targeted by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain

(2010) Tomoko Takahashi et al.   PAIN

H2S mediates O2 sensing in the carotid body

(2010) Y.-J. Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen sulfide in the pathogenesis of atherosclerosis and its therapeutic potential

(2010) Edward G Lynn et al.   Expert Review of Clinical Pharmacology

The Effect of Hydrogen Sulfide Donors on Lipopolysaccharide-Induced Formation of Inflammatory Mediators in Macrophages

(2009) Matthew Whiteman et al.   ANTIOXIDANTS & REDOX SIGNALING

Anti-apoptotic action of hydrogen sulfide is associated with early JNK inhibition

(2009) Sa Shi et al.   CELL BIOLOGY INTERNATIONAL

Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling

(2009) John W. Calvert et al.   CIRCULATION RESEARCH

Site-Directed Mutagenesis on Human Cystathionine-γ-Lyase Reveals Insights into the Modulation of H2S Production

(2009) Shufen Huang et al.   JOURNAL OF MOLECULAR BIOLOGY

Hydrogen sulfide: a new EDRF

(2009) Rui Wang   KIDNEY INTERNATIONAL

Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalopathy

(2009) Valeria Tiranti et al.   NATURE MEDICINE

Hydrogen sulphide-generating pathways in haemodialysis patients: a study on relevant metabolites and transcriptional regulation of genes encoding for key enzymes

(2009) A. F. Perna et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Hydrogen sulfide is an endogenous stimulator of angiogenesis

(2009) A. Papapetropoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H2S Signals Through Protein S-Sulfhydration

(2009) A. K. Mustafa et al.   Science Signaling

3-Mercaptopyruvate Sulfurtransferase Produces Hydrogen Sulfide and Bound Sulfane Sulfur in the Brain

(2008) Norihiro Shibuya et al.   ANTIOXIDANTS & REDOX SIGNALING

Kinetic Properties of Polymorphic Variants and Pathogenic Mutants in Human Cystathionine γ-Lyase†

(2008) Weidong Zhu et al.   BIOCHEMISTRY

Characterization of a Novel, Water-Soluble Hydrogen Sulfide–Releasing Molecule (GYY4137)

(2008) Ling Li et al.   CIRCULATION

Nitrotyrosinylation, remodeling and endothelial-myocyte uncoupling in iNOS, cystathionine beta synthase (CBS) knockouts and iNOS/CBS double knockout mice

(2008) Soumi Kundu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine  -Lyase

(2008) G. Yang et al.   SCIENCE

H2S preconditioning-induced PKC activation regulates intracellular calcium handling in rat cardiomyocytes

(2007) Ting-Ting Pan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY