Antitumor effect of sikokianin C, a selective cystathionine β-synthase inhibitor, against human colon cancer in vitro and in vivo

Discovery of selective cystathionine β-synthase inhibitors by high-throughput screening with a fluorescent thiol probe

(2017) Weining Niu et al.   MedChemComm

Key Residues Involved in the Interaction between Cydia pomonella Pheromone Binding Protein 1 (CpomPBP1) and Codlemone

(2016) Zhen Tian et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug Approach

(2016) Celia Chao et al.   MOLECULAR MEDICINE

Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer

(2016) Nadiya Druzhyna et al.   PHARMACOLOGICAL RESEARCH

Expression profile of hydrogen sulfide and its synthases correlates with tumor stage and grade in urothelial cell carcinoma of bladder

(2016) Jun-Wei Gai et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Structural insights into Cydia pomonella pheromone binding protein 2 mediated prediction of potentially active semiochemicals

(2016) Zhen Tian et al.   Scientific Reports

The Therapeutic Potential of Cystathionine β-Synthetase/Hydrogen Sulfide Inhibition in Cancer

(2015) Mark R. Hellmich et al.   ANTIOXIDANTS & REDOX SIGNALING

S-Glutathionylation Enhances Human Cystathionine β-Synthase Activity Under Oxidative Stress Conditions

(2015) Wei-Ning Niu et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of cystathionine β-synthase in human breast Cancer

(2015) Suvajit Sen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gasotransmitters in cancer: from pathophysiology to experimental therapy

(2015) Csaba Szabo   NATURE REVIEWS DRUG DISCOVERY

Characterization of a lambda-cyhalothrin metabolizing glutathione S-transferase CpGSTd1 from Cydia pomonella (L.)

(2014) Jiyuan Liu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

H2S and its role in redox signaling

(2014) Omer Kabil et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Key Amino Acid Associated with Acephate Detoxification by Cydia pomonella Carboxylesterase Based on Molecular Dynamics with Alanine Scanning and Site-Directed Mutagenesis

(2014) Xue Qing Yang et al.   Journal of Chemical Information and Modeling

Identification of Cystathionine β-Synthase Inhibitors Using a Hydrogen Sulfide Selective Probe

(2013) Megan K. Thorson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzymology of H2S Biogenesis, Decay and Signaling

(2013) Omer Kabil et al.   ANTIOXIDANTS & REDOX SIGNALING

Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE)

(2013) Antonia Asimakopoulou et al.   BRITISH JOURNAL OF PHARMACOLOGY

High-throughput tandem-microwell assay identifies inhibitors of the hydrogen sulfide signaling pathway

(2013) Yueyang Zhou et al.   CHEMICAL COMMUNICATIONS

Cystathionine Beta-Synthase (CBS) Contributes to Advanced Ovarian Cancer Progression and Drug Resistance

(2013) Sanjib Bhattacharyya et al.   PLoS One

Tumor-derived hydrogen sulfide, produced by cystathionine- -synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer

(2013) C. Szabo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production

(2012) M. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redox Biochemistry of Hydrogen Sulfide

(2010) Omer Kabil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessing the Performance of the MM/PBSA and MM/GBSA Methods. 1. The Accuracy of Binding Free Energy Calculations Based on Molecular Dynamics Simulations

(2010) Tingjun Hou et al.   Journal of Chemical Information and Modeling

Assessing the performance of the molecular mechanics/Poisson Boltzmann surface area and molecular mechanics/generalized Born surface area methods. II. The accuracy of ranking poses generated from docking

(2010) Tingjun Hou et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Hydrogen Sulfide: From Brain to Gut

(2009) Hideo Kimura   ANTIOXIDANTS & REDOX SIGNALING

Relative Contributions of Cystathionine β-Synthase and γ-Cystathionase to H2S Biogenesis via Alternative Trans-sulfuration Reactions

(2009) Sangita Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Empirical Scoring Functions for Advanced Protein−Ligand Docking with PLANTS

(2009) Oliver Korb et al.   Journal of Chemical Information and Modeling