Allosteric control of human cystathionine β-synthase activity by a redox active disulfide bond

Discovery of selective cystathionine β-synthase inhibitors by high-throughput screening with a fluorescent thiol probe

(2017) Weining Niu et al.   MedChemComm

Kinetic stability of cystathionine beta-synthase can be modulated by structural analogs of S-adenosylmethionine: Potential approach to pharmacological chaperone therapy for homocystinuria

(2016) Tomas Majtan et al.   BIOCHIMIE

Kinetics of Nitrite Reduction and Peroxynitrite Formation by Ferrous Heme in Human Cystathionine β-Synthase

(2016) Sebastián Carballal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S-Glutathionylation Enhances Human Cystathionine β-Synthase Activity Under Oxidative Stress Conditions

(2015) Wei-Ning Niu et al.   ANTIOXIDANTS & REDOX SIGNALING

S-Adenosyl-l-methionine Modulates CO and NO•Binding to the Human H2S-generating Enzyme Cystathionine β-Synthase

(2015) João B. Vicente et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

H2S and its role in redox signaling

(2014) Omer Kabil et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Inter-domain Communication of Human Cystathionine β-Synthase

(2014) Thomas J. McCorvie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blue Light-induced Dimerization of Monomeric Aureochrome-1 Enhances Its Affinity for the Target Sequence

(2014) Osamu Hisatomi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NO•Binds Human Cystathionine β-Synthase Quickly and Tightly

(2014) João B. Vicente et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative measurement of redox potential in hypoxic cells using SERS nanosensors

(2014) Jing Jiang et al.   Nanoscale

Nitrite Reductase Activity and Inhibition of H2S Biogenesis by Human Cystathionine ß-Synthase

(2014) Carmen Gherasim et al.   PLoS One

Structural insight into the molecular mechanism of allosteric activation of human cystathionine β-synthase byS-adenosylmethionine

(2014) June Ereño-Orbea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unraveling the Redox Properties of the Global Regulator FurA from Anabaena sp. PCC 7120: Disulfide Reductase Activity Based on Its CXXC Motifs

(2013) Laura Botello-Morte et al.   ANTIOXIDANTS & REDOX SIGNALING

Enzymology of H2S Biogenesis, Decay and Signaling

(2013) Omer Kabil et al.   ANTIOXIDANTS & REDOX SIGNALING

Kinetics of Reversible Reductive Carbonylation of Heme in Human Cystathionine β-Synthase

(2013) Sebastián Carballal et al.   BIOCHEMISTRY

Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE)

(2013) Antonia Asimakopoulou et al.   BRITISH JOURNAL OF PHARMACOLOGY

Structural basis of regulation and oligomerization of human cystathionine  -synthase, the central enzyme of transsulfuration

(2013) J. Ereno-Orbea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-trappable fluorescent probes for endogenous hydrogen sulfide signaling and imaging H2O2-dependent H2S production

(2013) V. S. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Post-Translational Control of Protein Function by Disulfide Bond Cleavage

(2012) Kristina M. Cook et al.   ANTIOXIDANTS & REDOX SIGNALING

Imaging mitochondrial redox potential and its possible link to tumor metastatic potential

(2012) Lin Z. Li   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Hyperpolarized 13C dehydroascorbate as an endogenous redox sensor for in vivo metabolic imaging

(2011) K. R. Keshari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluorescent Protein-Based Redox Probes

(2010) Andreas J. Meyer et al.   ANTIOXIDANTS & REDOX SIGNALING

Free and Acid-Labile Hydrogen Sulfide Concentrations in Mouse Tissues: Anomalously High Free Hydrogen Sulfide in Aortic Tissue

(2010) Michael D. Levitt et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Biochemistry of Hydrogen Sulfide

(2010) Omer Kabil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen Sulfide: From Brain to Gut

(2009) Hideo Kimura   ANTIOXIDANTS & REDOX SIGNALING

Inactivation of cystathionine β-synthase with peroxynitrite

(2009) Laura Celano et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Relative Contributions of Cystathionine β-Synthase and γ-Cystathionase to H2S Biogenesis via Alternative Trans-sulfuration Reactions

(2009) Sangita Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of the heme electronic structure and cystathionine β-synthase activity by second coordination sphere ligands: The role of heme ligand switching in redox regulation

(2009) Sangita Singh et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

H2S Signals Through Protein S-Sulfhydration

(2009) A. K. Mustafa et al.   Science Signaling

Whole tissue hydrogen sulfide concentrations are orders of magnitude lower than presently accepted values

(2008) Julie Furne et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Active Cystathionine β-Synthase Can Be Expressed in Heme-free Systems in the Presence of Metal-substituted Porphyrins or a Chemical Chaperone

(2008) Tomas Majtan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY