Vascular complications of cystathionine β-synthase deficiency: future directions for homocysteine-to-hydrogen sulfide research

oxLDL-induced decrease in lipid order of membrane domains is inversely correlated with endothelial stiffness and network formation

(2010) Tzu Pin Shentu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Extracellular transsulfuration generates hydrogen sulfide from homocysteine and protects endothelium from redox stress

(2010) Shawn E. Bearden et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Homocysteine Lowering in End-Stage Renal Disease

(2010) Lawrence de Koning et al.   CIRCULATION

A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment

(2010) Kenneth N. Maclean et al.   MOLECULAR GENETICS AND METABOLISM

H2S mediates O2 sensing in the carotid body

(2010) Y.-J. Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial Activation in Lacunar Stroke Subtypes

(2010) Iris L.H. Knottnerus et al.   STROKE

Development of Hydrogen Sulfide-Based Therapeutics for Cardiovascular Disease

(2010) Benjamin L. Predmore et al.   Journal of Cardiovascular Translational Research

Hypoxic pulmonary vasodilation: a paradigm shift with a hydrogen sulfide mechanism

(2009) Kenneth R. Olson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Lacunar stroke is associated with diffuse blood-brain barrier dysfunction

(2009) Joanna M. Wardlaw et al.   ANNALS OF NEUROLOGY

The Hydrogen Sulfide Donor NaHS Promotes Angiogenesis in a Rat Model of Hind Limb Ischemia

(2009) Ming-Jie Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Hyperhomocysteinemia Promotes Inflammatory Monocyte Generation and Accelerates Atherosclerosis in Transgenic Cystathionine β-Synthase–Deficient Mice

(2009) Daqing Zhang et al.   CIRCULATION

Hydrogen Sulfide Improves Survival After Cardiac Arrest and Cardiopulmonary Resuscitation via a Nitric Oxide Synthase 3–Dependent Mechanism in Mice

(2009) Shizuka Minamishima et al.   CIRCULATION

Acceleration of brain amyloidosis in an Alzheimer’s disease mouse model by a folate, vitamin B6 and B12-deficient diet

(2009) Jia-Min Zhuo et al.   EXPERIMENTAL GERONTOLOGY

Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice

(2009) Hieronim Jakubowski et al.   FASEB JOURNAL

Serum vitamin B12, folate, and homocysteine levels and their association with clinical and electrophysiological parameters in multiple sclerosis

(2009) B. Kocer et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Blood-brain barrier permeability is increased in normal-appearing white matter in patients with lacunar stroke and leucoaraiosis

(2009) R Topakian et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Hydrogen sulfide mitigates matrix metalloproteinase-9 activity and neurovascular permeability in hyperhomocysteinemic mice

(2009) Neetu Tyagi et al.   NEUROCHEMISTRY INTERNATIONAL

Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver

(2009) Natalia Guillén et al.   PHYSIOLOGICAL GENOMICS

H2S Signals Through Protein S-Sulfhydration

(2009) A. K. Mustafa et al.   Science Signaling

Higher Systolic Blood Pressure Is Associated With Increased Water Diffusivity in Normal-Appearing White Matter

(2009) Alasdair M. J. MacLullich et al.   STROKE

Chronic diet-induced hyperhomocysteinemia impairs eNOS regulation in mouse mesenteric arteries

(2008) Robin C. Looft-Wilson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The Treatment of Hyperhomocysteinemia

(2008) Bradley A. Maron et al.   Annual Review of Medicine

Association of Plasma Total Homocysteine Levels With Subclinical Brain Injury

(2008) Sudha Seshadri et al.   ARCHIVES OF NEUROLOGY

Murine Models of Hyperhomocysteinemia and Their Vascular Phenotypes

(2008) Sanjana Dayal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Effect of hyperhomocysteinemia on the protein kinase DYRK1A in liver of mice

(2008) Julien Hamelet et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cystathionine beta synthase deficiency induces catalase-mediated hydrogen peroxide detoxification in mice liver

(2008) Julien Hamelet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

GABAA receptor agonist mitigates homocysteine-induced cerebrovascular remodeling in knockout mice

(2008) Munish Kumar et al.   BRAIN RESEARCH

Hypertension and Cerebrovascular Dysfunction

(2008) Costantino Iadecola et al.   Cell Metabolism

Apolipoprotein E Knockout Models

(2008) Genovefa Kolovou et al.   CURRENT PHARMACEUTICAL DESIGN

Hyperhomocysteinemia induced by methionine supplementation does not independently cause atherosclerosis in C57BL/6J mice

(2008) Ji Zhou et al.   FASEB JOURNAL

Mutations in cystathionine β-synthase or methylenetetrahydrofolate reductase gene increase N-homocysteinylated protein levels in humans

(2008) Hieronim Jakubowski et al.   FASEB JOURNAL

Homocysteine and inflammation as main determinants of oxidative stress in the elderly

(2008) Emilie Ventura et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetic background in apolipoprotein A-I and cystathionine b-synthase deficiency

(2008) Ricardo Carnicer   Frontiers in Bioscience-Landmark

Genetic background conversion ameliorates semi-lethality and permits behavioral analyses in cystathionine β-synthase-deficient mice, an animal model for hyperhomocysteinemia

(2008) Noriyuki Akahoshi et al.   HUMAN MOLECULAR GENETICS

Effect of folate on neointima formation and matrix metalloproteinase-9 expression after balloon injury in hyperhomocysteinemic rabbits

(2008) FenYe Liu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Effect of Folic Acid and B Vitamins on Risk of Cardiovascular Events and Total Mortality Among Women at High Risk for Cardiovascular Disease

(2008) Christine M. Albert et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Mortality and Cardiovascular Events in Patients Treated With Homocysteine-Lowering B Vitamins After Coronary Angiography

(2008) Marta Ebbing et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Nitrotyrosinylation, remodeling and endothelial-myocyte uncoupling in iNOS, cystathionine beta synthase (CBS) knockouts and iNOS/CBS double knockout mice

(2008) Soumi Kundu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Serum homocysteine levels in relation to clinical progression in multiple sclerosis

(2008) C E Teunissen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Apolipoprotein E, Amyloid-β, and Blood-Brain Barrier Permeability in Alzheimer Disease

(2008) John E. Donahue et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Birth Prevalence of Homocystinuria in Central Europe: Frequency and Pathogenicity of Mutation c.1105C>T (p.R369C) in the Cystathionine Beta-Synthase Gene

(2008) Miroslav Janošík et al.   JOURNAL OF PEDIATRICS

Simvastatin reverses the hypertension of heterozygous mice lacking cystathionine β-synthase and apolipoprotein A-I

(2008) Ricardo Carnicer et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

H2S and HS− donor NaHS releases nitric oxide from nitrosothiols, metal nitrosyl complex, brain homogenate and murine L1210 leukaemia cells

(2008) Karol Ondrias et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Homocysteine and Its Relationship to Stroke Subtypes in a UK Black Population

(2008) Usman Khan et al.   STROKE

Changes in Background Blood–Brain Barrier Integrity Between Lacunar and Cortical Ischemic Stroke Subtypes

(2008) Joanna M. Wardlaw et al.   STROKE