Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter

17 -estradiol attenuates homocysteine-induced oxidative stress and inflammatory response as well as MAPKs cascade via activating PI3-K/Akt signal transduction pathway in Raw 264.7 cells

(2015) Y. Zhang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Endogenous Hydrogen Sulfide Production Is Essential for Dietary Restriction Benefits

(2015) Christopher Hine et al.   CELL

Hydrogen Sulfide Epigenetically Attenuates Homocysteine-Induced Mitochondrial Toxicity Mediated Through NMDA Receptor in Mouse Brain Endothelial (bEnd3) Cells

(2014) Pradip K. Kamat et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hyperhomocysteinemia and Neurologic Disorders: a Review

(2014) Ramin Ansari et al.   Journal of Clinical Neurology

Resveratrol protects against homocysteine-induced cell damage via cell stress response in neuroblastoma cells

(2014) Monica Currò et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Notable epigenetic role of hyperhomocysteinemia in atherogenesis

(2014) Shuyu Zhou et al.   Lipids in Health and Disease

Statins upregulate cystathionine γ-lyase transcription and H2S generation via activating Akt signaling in macrophage

(2014) Yuan Xu et al.   PHARMACOLOGICAL RESEARCH

Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis

(2014) Kyle L. Flannigan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen Sulfide and the Pathogenesis of Atherosclerosis

(2013) Sarathi Mani et al.   ANTIOXIDANTS & REDOX SIGNALING

The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation

(2013) Smriti Murali Krishna et al.   ATHEROSCLEROSIS

Dysregulation of cystathionine γ-lyase (CSE)/hydrogen sulfide pathway contributes to ox-LDL-induced inflammation in macrophage

(2013) Xian-Hui Wang et al.   CELLULAR SIGNALLING

Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis

(2013) Sarathi Mani et al.   CIRCULATION

Homocysteine induces inflammatory transcriptional signaling in monocytes 

(2013) Hong Wang   Frontiers in Bioscience-Landmark

Promoted Interaction of Nuclear Factor- B with Demethylated Cystathionine- -Synthetase Gene Contributes to Gastric Hypersensitivity in Diabetic Rats

(2013) H.-H. Zhang et al.   JOURNAL OF NEUROSCIENCE

Hydrogen sulfide attenuates neurodegeneration and neurovascular dysfunction induced by intracerebral-administered homocysteine in mice

(2013) P.K. Kamat et al.   NEUROSCIENCE

Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed

(2012) Rui Wang   PHYSIOLOGICAL REVIEWS

Cystathionine β-synthase and cystathionine γ-lyase double gene transfer ameliorate homocysteine-mediated mesangial inflammation through hydrogen sulfide generation

(2010) Utpal Sen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Vascular complications of cystathionine β-synthase deficiency: future directions for homocysteine-to-hydrogen sulfide research

(2010) Richard S. Beard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hydrogen Sulfide: Neurophysiology and Neuropathology

(2010) Li-Fang Hu et al.   ANTIOXIDANTS & REDOX SIGNALING

Homocysteine Inhibits Arterial Endothelial Cell Growth Through Transcriptional Downregulation of Fibroblast Growth Factor-2 Involving G Protein and DNA Methylation

(2008) Po-Yuan Chang et al.   CIRCULATION RESEARCH

H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine  -Lyase

(2008) G. Yang et al.   SCIENCE