Hydrogen Sulfide Protects Against Cellular Senescence via S-Sulfhydration of Keap1 and Activation of Nrf2

Integrated Stress Response Modulates Cellular Redox State via Induction of Cystathionine γ-Lyase

(2012) Jeffrey G. Dickhout et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen Sulfide-Linked Sulfhydration of NF-κB Mediates Its Antiapoptotic Actions

(2012) Nilkantha Sen et al.   MOLECULAR CELL

Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration

(2012) Motohiro Nishida et al.   Nature Chemical Biology

Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed

(2012) Rui Wang   PHYSIOLOGICAL REVIEWS

Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production

(2012) M. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pathogenic Role of Cystathionine γ-Lyase/Hydrogen Sulfide in Streptozotocin-Induced Diabetes in Mice

(2011) Guangdong Yang et al.   AMERICAN JOURNAL OF PATHOLOGY

Hydrogen Sulfide Ameliorates Tobacco Smoke-Induced Oxidative Stress and Emphysema in Mice

(2011) Weihong Han et al.   ANTIOXIDANTS & REDOX SIGNALING

Modification of Keap1 Cysteine Residues by Sulforaphane

(2011) Chenqi Hu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

A critical life-supporting role for cystathionine γ-lyase in the absence of dietary cysteine supply

(2011) Sarathi Mani et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gastrokine 1 induces senescence through p16/Rb pathway activation in gastric cancer cells

(2011) Rui Xing et al.   GUT

Production of H2S by 3-mercaptopyruvate sulphurtransferase

(2011) K. Tanizawa   JOURNAL OF BIOCHEMISTRY

Specificity Protein-1 as a Critical Regulator of Human Cystathionine γ-Lyase in Smooth Muscle Cells

(2011) Guangdong Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function

(2011) K. Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H2S-Induced Sulfhydration of the Phosphatase PTP1B and Its Role in the Endoplasmic Reticulum Stress Response

(2011) N. Krishnan et al.   Science Signaling

Hydrogen sulfide mediates the anti-survival effect of sulforaphane on human prostate cancer cells

(2011) Yanxi Pei et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The hydrogen sulfide signaling system: changes during aging and the benefits of caloric restriction

(2010) Benjamin L. Predmore et al.   AGE

Discovery of the Negative Regulator of Nrf2, Keap1: A Historical Overview

(2010) Ken Itoh et al.   ANTIOXIDANTS & REDOX SIGNALING

Genetic and Pharmacologic Hydrogen Sulfide Therapy Attenuates Ischemia-Induced Heart Failure in Mice

(2010) John W. Calvert et al.   CIRCULATION

Redox Biochemistry of Hydrogen Sulfide

(2010) Omer Kabil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Feedback between p21 and reactive oxygen production is necessary for cell senescence

(2010) João F Passos et al.   Molecular Systems Biology

Early onset senescence occurs when fibroblasts lack the glutamate–cysteine ligase modifier subunit

(2009) Ying Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hydrogen sulfide is an endogenous stimulator of angiogenesis

(2009) A. Papapetropoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H2S Signals Through Protein S-Sulfhydration

(2009) A. K. Mustafa et al.   Science Signaling

Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila

(2008) Gerasimos P. Sykiotis et al.   DEVELOPMENTAL CELL

Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

(2008) C.J. Harvey et al.   FREE RADICAL BIOLOGY AND MEDICINE

Adaptive response to GSH depletion and resistance to l-buthionine-(S,R)-sulfoximine: involvement of Nrf2 activation

(2008) Hyang-Rim Lee et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Bach1 inhibits oxidative stress–induced cellular senescence by impeding p53 function on chromatin

(2008) Yoshihiro Dohi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MEDICINE: Nothing Rotten About Hydrogen Sulfide's Medical Promise

(2008) M. Leslie   SCIENCE

H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine  -Lyase

(2008) G. Yang et al.   SCIENCE