Myeloperoxidase: A Leukocyte-Derived Protagonist of Inflammation and Cardiovascular Disease

Dual Functionality of Myeloperoxidase in Rotenone-Exposed Brain-Resident Immune Cells

(2011) Chi Young Chang et al.   AMERICAN JOURNAL OF PATHOLOGY

Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis

(2011) Teluguakula Narasaraju et al.   AMERICAN JOURNAL OF PATHOLOGY

Resolution of neutrophilic inflammation by H2O2 in antigen-induced arthritis

(2011) Fernando Lopes et al.   ARTHRITIS AND RHEUMATISM

Hypochlorite-modified low-density lipoprotein induces the apoptotic machinery in Jurkat T-cell lines

(2011) Ulrike Resch et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of the chlorinating activity of myeloperoxidase by tempol: revisiting the kinetics and mechanisms

(2011) Raphael F. Queiroz et al.   BIOCHEMICAL JOURNAL

Kinetics of 3-Chlorotyrosine Formation and Loss due to Hypochlorous Acid and Chloramines

(2011) Matthew P. Curtis et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Myeloperoxidase Improves Risk Stratification in Patients with Ischemia and Normal Cardiac Troponin I Concentrations

(2011) F. S. Apple et al.   CLINICAL CHEMISTRY

Oxidative Modification of Lipoproteins: Mechanisms, Role in Inflammation and Potential Clinical Applications in Cardiovascular Disease

(2011) Sotirios Tsimikas et al.   CURRENT PHARMACEUTICAL DESIGN

Myeloperoxidase deficiency preserves vasomotor function in humans

(2011) Tanja K. Rudolph et al.   EUROPEAN HEART JOURNAL

Diagnostic efficacy of myeloperoxidase for the detection of acute coronary syndromes

(2011) Marcin Sawicki et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Decreased myeloperoxidase expressing cells in the aged rat brain after excitotoxic damage

(2011) Oscar Campuzano et al.   EXPERIMENTAL GERONTOLOGY

Melatonin Can Mediate Its Vascular Protective Effect by Modulating Free Iron Level by Inhibiting Hypochlorous Acid–Mediated Hemoprotein Heme Destruction

(2011) Dhiman Maitra et al.   HYPERTENSION

Urate as a Physiological Substrate for Myeloperoxidase

(2011) Flavia C. Meotti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

2-Thioxanthines Are Mechanism-based Inactivators of Myeloperoxidase That Block Oxidative Stress during Inflammation

(2011) Anna-Karin Tidén et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ultrastructural characterization of cystic fibrosis sputum using atomic force and scanning electron microscopy

(2011) Reinhard Manzenreiter et al.   Journal of Cystic Fibrosis

The innate immune system and the clearance of apoptotic cells

(2011) Andrew Devitt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Innate immune signaling in cardiac ischemia

(2011) Fatih Arslan et al.   Nature Reviews Cardiology

Human myeloperoxidase in innate and acquired immunity

(2010) Juergen Arnhold et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages

(2010) Amanda E. Lane et al.   BIOCHEMICAL JOURNAL

CO Binding and Ligand Discrimination in Human Myeloperoxidase

(2010) Emma J. Murphy et al.   BIOCHEMISTRY

The glycosylation of myeloperoxidase

(2010) Tina Ravnsborg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity

(2010) K. D. Metzler et al.   BLOOD

Myeloperoxidase attracts neutrophils by physical forces

(2010) A. Klinke et al.   BLOOD

Neutrophils, Hypercholesterolemia, and Atherogenesis

(2010) Stanley L. Hazen   CIRCULATION

Inflammation and Atrial Fibrillation

(2010) Nobuhisa Hagiwara   CIRCULATION JOURNAL

Binding of proteinase 3 and myeloperoxidase to endothelial cells: ANCA-mediated endothelial damage through ADCC?

(2010) B. E. P. B. BALLIEUX et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Use of Myeloperoxidase for Risk Stratification in Acute Heart Failure

(2010) T. Reichlin et al.   CLINICAL CHEMISTRY

Prognostic value of myeloperoxidase in coronary artery disease: comparison of unstable and stable angina patients

(2010) Raquel Melchior Roman et al.   CORONARY ARTERY DISEASE

Assessment of multiple cardiac biomarkers in non-ST-segment elevation acute coronary syndromes: observations from the MERLIN-TIMI 36 Trial

(2010) Benjamin M. Scirica et al.   EUROPEAN HEART JOURNAL

Myeloperoxidase level in patients with stable coronary artery disease and acute coronary syndromes

(2010) G. Ndrepepa et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase-deficient mice during acute inflammation

(2010) Lukas Kubala et al.   FREE RADICAL BIOLOGY AND MEDICINE

Myeloperoxidase as a diagnostic and prognostic marker in cardiology: beware of pre-analytical factors that may influence results

(2010) R. K. Schindhelm et al.   International Journal of Laboratory Hematology

Glycosylation Pattern of Mature Dimeric Leukocyte and Recombinant Monomeric Myeloperoxidase

(2010) Pierre Van Antwerpen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myeloperoxidase-induced Genomic DNA-centered Radicals

(2010) Sandra E. Gomez-Mejiba et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nature of the Ferryl Heme in Compounds I and II

(2010) Andrea Gumiero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibrosis and Cardiac Arrhythmias

(2010) Sanne de Jong et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention

(2010) Michael J. Davies   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Myeloperoxidase-dependent oxidative metabolism of nitric oxide in the cystic fibrosis airway

(2010) Anna L.P. Chapman et al.   Journal of Cystic Fibrosis

Myeloperoxidase and C-Reactive Protein Have Combined Utility for Long-Term Prediction of Cardiovascular Mortality After Coronary Angiography

(2010) Claire L. Heslop et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Heat shock transcription factor-1 inhibits H2O2-induced apoptosis via down-regulation of reactive oxygen species in cardiac myocytes

(2010) Lei Zhang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation

(2010) Volker Rudolph et al.   NATURE MEDICINE

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Usefulness of Myeloperoxidase Levels in Healthy Elderly Subjects to Predict Risk of Developing Heart Failure

(2009) W.H. Wilson Tang et al.   AMERICAN JOURNAL OF CARDIOLOGY

15-Epi-lipoxin A4Inhibits Myeloperoxidase Signaling and Enhances Resolution of Acute Lung Injury

(2009) Driss El Kebir et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Myeloperoxidase: Molecular Mechanisms of Action and Their Relevance to Human Health and Disease

(2009) Betty S. van der Veen et al.   ANTIOXIDANTS & REDOX SIGNALING

Serotonin as a physiological substrate for myeloperoxidase and its superoxide-dependent oxidation to cytotoxic tryptamine-4,5-dione

(2009) Valdecir F. Ximenes et al.   BIOCHEMICAL JOURNAL

Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13

(2009) J. Chen et al.   BLOOD

Mechanisms underlying neutrophil-mediated monocyte recruitment

(2009) O. Soehnlein et al.   BLOOD

Monocytes and neutrophils expressing myeloperoxidase occur in fibrous caps and thrombi in unstable coronary plaques

(2009) Fabio R Tavora et al.   BMC Cardiovascular Disorders

What Are the Plasma Targets of the Oxidant Hypochlorous Acid? A Kinetic Modeling Approach

(2009) David I. Pattison et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Level and Prognostic Value of Serum Myeloperoxidase in Patients With Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

(2009) Li-Teh Chang et al.   CIRCULATION JOURNAL

Myeloperoxidase is not useful for the early assessment of patients with chest pain

(2009) Kai M. Eggers et al.   CLINICAL BIOCHEMISTRY

Site-specific hypochlorous acid-induced oxidation of recombinant human myoglobin affects specific amino acid residues and the rate of cytochrome b5-mediated heme reduction

(2009) Andrea J. Szuchman-Sapir et al.   FREE RADICAL BIOLOGY AND MEDICINE

Modification of High Density Lipoprotein by Myeloperoxidase Generates a Pro-inflammatory Particle

(2009) Arundhati Undurti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myeloperoxidase Deficiency Attenuates Lipopolysaccharide-Induced Acute Lung Inflammation and Subsequent Cytokine and Chemokine Production

(2009) A. Haegens et al.   JOURNAL OF IMMUNOLOGY

Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan

(2009) Martin D. Rees et al.   MATRIX BIOLOGY

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

Methionine oxidation contributes to bacterial killing by the myeloperoxidase system of neutrophils

(2009) H. Rosen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophil granule proteins tune monocytic cell function

(2009) Oliver Soehnlein et al.   TRENDS IN IMMUNOLOGY

Myeloperoxidase, Subclinical Atherosclerosis, and Cardiovascular Disease Events

(2009) Nathan D. Wong et al.   JACC-Cardiovascular Imaging

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Prognostic Value of Admission Myeloperoxidase Levels in Patients With ST-Segment Elevation Myocardial Infarction and Cardiogenic Shock

(2008) Alberto Dominguez-Rodriguez et al.   AMERICAN JOURNAL OF CARDIOLOGY

Mammalian Heme Peroxidases: From Molecular Mechanisms to Health Implications

(2008) Michael J. Davies et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of reactive oxygen species and Bax in oxidized low density lipoprotein-induced apoptosis of human monocytes

(2008) Natalia Ermak et al.   ATHEROSCLEROSIS

Kinetic evidence for rapid oxidation of (–)-epicatechin by human myeloperoxidase

(2008) Holger Spalteholz et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid

(2008) Mitchell M. Lloyd et al.   BIOCHEMICAL JOURNAL

Hypobromous acid and bromamine production by neutrophils and modulation by superoxide

(2008) Anna L. P. Chapman et al.   BIOCHEMICAL JOURNAL

Hypochlorous Acid Damages Histone Proteins Forming 3-Chlorotyrosine and 3,5-Dichlorotyrosine

(2008) Joseph I. Kang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Myeloperoxidase Delays Neutrophil Apoptosis Through CD11b/CD18 Integrins and Prolongs Inflammation

(2008) Driss El Kebir et al.   CIRCULATION RESEARCH

Plasma levels of myeloperoxidase are not elevated in patients with stable coronary artery disease

(2008) Lukas Kubala et al.   CLINICA CHIMICA ACTA

Concurrent evaluation of novel cardiac biomarkers in acute coronary syndrome: myeloperoxidase and soluble CD40 ligand and the risk of recurrent ischaemic events in TACTICS-TIMI 18

(2008) David A. Morrow et al.   EUROPEAN HEART JOURNAL

Microglia and myeloperoxidase: A deadly partnership in neurodegenerative disease

(2008) Doris L. Lefkowitz et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neutrophil apoptosis and the resolution of infection

(2008) Adam D. Kennedy et al.   IMMUNOLOGIC RESEARCH

Aberrant Expression of Myeloperoxidase in Astrocytes Promotes Phospholipid Oxidation and Memory Deficits in a Mouse Model of Alzheimer Disease

(2008) Richard A. Maki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bivalirudin Decreases NO Bioavailability by Vascular Immobilization of Myeloperoxidase

(2008) V. Rudolph et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Activation of c-Jun N-terminal kinase is essential for oxidative stress-induced Jurkat cell apoptosis by monochloramine

(2008) Tetsuya Ogino et al.   LEUKEMIA RESEARCH

Neutrophil Adhesion and Activation under Flow

(2008) Alexander Zarbock et al.   MICROCIRCULATION

The peroxidase-cyclooxygenase superfamily: Reconstructed evolution of critical enzymes of the innate immune system

(2008) Marcel Zamocky et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The long-term prognostic value of multiple biomarkers following a myocardial infarction

(2008) Trygve Brügger-Andersen et al.   THROMBOSIS RESEARCH

Phospholipid chlorohydrin induces leukocyte adhesion to ApoE−/− mouse arteries via upregulation of P-selectin

(2007) Gary J. Dever et al.   FREE RADICAL BIOLOGY AND MEDICINE