Hydrogen sulfide dysregulates the immune response by suppressing central carbon metabolism to promote tuberculosis

H2S inhalation-induced energy metabolism disturbance is involved in LPS mediated hepatocyte apoptosis through mitochondrial pathway

(2019) Jinming Guo et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Compromised Metabolic Reprogramming Is an Early Indicator of CD8+ T Cell Dysfunction during Chronic Mycobacterium tuberculosis Infection

(2019) Shannon L. Russell et al.   Cell Reports

Growth ofMycobacterium tuberculosisin vivo segregates with host macrophage metabolism and ontogeny

(2018) Lu Huang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection

(2018) Vineel P. Reddy et al.   Frontiers in Immunology

A Role for the Krebs Cycle Intermediate Citrate in Metabolic Reprogramming in Innate Immunity and Inflammation

(2018) Niamh C. Williams et al.   Frontiers in Immunology

Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis

(2018) Krishna C. Chinta et al.   Cell Reports

Mycobacterium tuberculosis induces decelerated bioenergetic metabolism in human macrophages

(2018) Bridgette M Cumming et al.   eLife

Hydrogen sulfide inhibits NLRP3 inflammasome activation and reduces cytokine production bothin vitroand in a mouse model of inflammation

(2017) Mariela Castelblanco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIF1α-Induced Glycolysis Metabolism Is Essential to the Activation of Inflammatory Macrophages

(2017) Ting Wang et al.   MEDIATORS OF INFLAMMATION

Macrophage Immunometabolism: Where Are We (Going)?

(2017) Jan Van den Bossche et al.   TRENDS IN IMMUNOLOGY

Non-Steroidal Anti-inflammatory Drugs As Host-Directed Therapy for Tuberculosis: A Systematic Review

(2017) Vera M. Kroesen et al.   Frontiers in Immunology

d-Penicillamine modulates hydrogen sulfide (H2S) pathway through selective inhibition of cystathionine-γ-lyase

(2016) Vincenzo Brancaleone et al.   BRITISH JOURNAL OF PHARMACOLOGY

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

(2016) Evanna L. Mills et al.   CELL

HIF1α and metabolic reprogramming in inflammation

(2016) Sarah E. Corcoran et al.   JOURNAL OF CLINICAL INVESTIGATION

HIF-1α Is an Essential Mediator of IFN-γ–Dependent Immunity toMycobacterium tuberculosis

(2016) Jonathan Braverman et al.   JOURNAL OF IMMUNOLOGY

The emerging role of gasotransmitters in the pathogenesis of tuberculosis

(2016) Krishna C. Chinta et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Metabolic reprogramming & inflammation: Fuelling the host response to pathogens

(2016) Laura E. Gleeson et al.   SEMINARS IN IMMUNOLOGY

Pyruvate Kinase M2: A Potential Target for Regulating Inflammation

(2016) Jose C. Alves-Filho et al.   Frontiers in Immunology

Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis

(2016) Ravinder Reddy Gaddam et al.   PLoS One

Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter

(2015) John L. Wallace et al.   NATURE REVIEWS DRUG DISCOVERY

H 2 S: A Novel Gasotransmitter that Signals by Sulfhydration

(2015) Bindu D. Paul et al.   TRENDS IN BIOCHEMICAL SCIENCES

Effect of hydrogen sulfide on inflammatory cytokines in acute myocardial ischemia injury in rats

(2015) FANG LIU et al.   Experimental and Therapeutic Medicine

Gasotransmitters: growing pains and joys

(2014) Rui Wang   TRENDS IN BIOCHEMICAL SCIENCES

Sulfide inhibition of and metabolism by cytochromecoxidase

(2013) Peter Nicholls et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects

(2013) Katalin Módis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms

(2013) Csaba Szabo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Metabolic Pathways in Immune Cell Activation and Quiescence

(2013) Erika L. Pearce et al.   IMMUNITY

IL-1  Promotes Antimicrobial Immunity in Macrophages by Regulating TNFR Signaling and Caspase-3 Activation

(2013) P. Jayaraman et al.   JOURNAL OF IMMUNOLOGY

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells

(2012) B. Everts et al.   BLOOD

Hydrogen sulfide inhibits the translational expression of hypoxia-inducible factor-1α

(2012) Bo Wu et al.   BRITISH JOURNAL OF PHARMACOLOGY

ATP-Citrate Lyase: A Key Player in Cancer Metabolism

(2012) N. Zaidi et al.   CANCER RESEARCH

Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production

(2012) M. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen Sulfide Inhibits Hypoxia- But Not Anoxia-Induced Hypoxia-Inducible Factor 1 Activation in a von Hippel-Lindau- and Mitochondria-Dependent Manner

(2011) Shinichi Kai et al.   ANTIOXIDANTS & REDOX SIGNALING

Analysis of Murine Genetic Predisposition to Pneumococcal Infection Reveals a Critical Role of Alveolar Macrophages in Maintaining the Sterility of the Lower Respiratory Tract

(2011) Keer Sun et al.   INFECTION AND IMMUNITY

Hydrogen Sulfide Is an Endogenous Potentiator of T Cell Activation

(2011) Thomas W. Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection

(2011) Bisweswar Nandi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hydrogen Sulfide Upregulates Cyclooxygenase-2 and Prostaglandin E Metabolite in Sepsis-Evoked Acute Lung Injury via Transient Receptor Potential Vanilloid Type 1 Channel Activation

(2011) S.-F. Ang et al.   JOURNAL OF IMMUNOLOGY

H2S transiently blocks IL-6 expression in rheumatoid arthritic fibroblast-like synoviocytes and deactivates p44/42 mitogen-activated protein kinase

(2010) Burkhard Kloesch et al.   CELL BIOLOGY INTERNATIONAL

NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment

(2010) E. J. Moon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen sulfide and inflammation: the good, the bad, the ugly and the promising

(2010) Matthew Whiteman et al.   Expert Review of Clinical Pharmacology

The Effect of Hydrogen Sulfide Donors on Lipopolysaccharide-Induced Formation of Inflammatory Mediators in Macrophages

(2009) Matthew Whiteman et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen sulfide from adipose tissue is a novel insulin resistance regulator

(2009) Xuejuan Feng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

No facilitator required for membrane transport of hydrogen sulfide

(2009) J. C. Mathai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heme Oxygenase-1-derived Carbon Monoxide Induces theMycobacterium tuberculosisDormancy Regulon

(2008) Ashwani Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine  -Lyase

(2008) G. Yang et al.   SCIENCE