Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1

New cellular and molecular targets for the treatment of portal hypertension

(2015) Jordi Gracia-Sancho et al.   Hepatology International

FoxO Proteins: Regulation and Molecular Targets in Liver Cancer

(2014) S. Carbajo-Pescador et al.   CURRENT MEDICINAL CHEMISTRY

Exploitation of Cholane Scaffold for the Discovery of Potent and Selective Farnesoid X Receptor (FXR) and G-Protein Coupled Bile Acid Receptor 1 (GP-BAR1) Ligands

(2014) Carmen Festa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Melatonin reduces endothelin-1 expression and secretion in colon cancer cells through the inactivation of FoxO-1 and NF-κβ

(2014) Josefa León et al.   JOURNAL OF PINEAL RESEARCH

Splanchnic vasodilation and hyperdynamic circulatory syndrome in cirrhosis

(2014) Massimo Bolognesi   WORLD JOURNAL OF GASTROENTEROLOGY

Bile Acid Receptor TGR5 Agonism Induces NO Production and Reduces Monocyte Adhesion in Vascular Endothelial Cells

(2013) Taiki Kida et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

GPBA: a GPCR for bile acids and an emerging therapeutic target for disorders of digestion and sensation

(2013) T Lieu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition

(2012) Barbara Renga et al.   FASEB JOURNAL

Ursodeoxycholic acid and bile-acid mimetics as therapeutic agents for cholestatic liver diseases: An overview of their mechanisms of action

(2012) Raoul Poupon   Clinics and Research in Hepatology and Gastroenterology

Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion

(2011) HE Parker et al.   BRITISH JOURNAL OF PHARMACOLOGY

Green Tea Polyphenol Epigallocatechin Gallate Reduces Endothelin-1 Expression and Secretion in Vascular Endothelial Cells: Roles for AMP-Activated Protein Kinase, Akt, and FOXO1

(2009) Chad E. N. Reiter et al.   ENDOCRINOLOGY

Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders

(2009) Stefano Fiorucci et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Bile-acid-activated farnesoid X receptor regulates hydrogen sulfide production and hepatic microcirculation

(2009) Barbara Renga et al.   WORLD JOURNAL OF GASTROENTEROLOGY