Cystathionine-γ-lyase ameliorates the histone demethylase JMJD3-mediated autoimmune response in rheumatoid arthritis

A critical epitope in CD147 facilitates memory CD4+ T-cell hyper-activation in rheumatoid arthritis

(2018) Na Guo et al.   Cellular & Molecular Immunology

Histone demethylase JMJD3 regulates fibroblast-like synoviocyte-mediated proliferation and joint destruction in rheumatoid arthritis

(2018) Wanwan Jia et al.   FASEB JOURNAL

S-propargyl-cysteine attenuates inflammatory response in rheumatoid arthritis by modulating the Nrf2-ARE signaling pathway

(2016) Wei-Jun Wu et al.   Redox Biology

Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter

(2015) John L. Wallace et al.   NATURE REVIEWS DRUG DISCOVERY

Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthritis

(2014) Hui-fang Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma

(2014) Rintaro Hashizume et al.   NATURE MEDICINE

Mechanisms, impact and management of pain in rheumatoid arthritis

(2014) David A. Walsh et al.   Nature Reviews Rheumatology

Hydrogen sulfide attenuates hypoxia-induced neurotoxicity through inhibiting microglial activation

(2014) Qun Zhang et al.   PHARMACOLOGICAL RESEARCH

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update

(2013) Josef S Smolen et al.   ANNALS OF THE RHEUMATIC DISEASES

Fibroblasts and synovial immunity

(2013) Michelle T Leech et al.   CURRENT OPINION IN PHARMACOLOGY

Gene networking and inflammatory pathway analysis in a JMJD3 knockdown human monocytic cell line

(2012) Nando Dulal Das et al.   CELL BIOCHEMISTRY AND FUNCTION

Epigenetic Regulation of Tumor Necrosis Factor α (TNFα) Release in Human Macrophages by HIV-1 Single-stranded RNA (ssRNA) Is Dependent on TLR8 Signaling

(2012) Xinbing Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

(2012) Laurens Kruidenier et al.   NATURE

Epigenetic regulation of osteoclast differentiation: Possible involvement of Jmjd3 in the histone demethylation of Nfatc1

(2011) Tetsuro Yasui et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Oleuropein Aglycone, an Olive Oil Compound, Ameliorates Development of Arthritis Caused by Injection of Collagen Type II in Mice

(2011) D. Impellizzeri et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Differing effects of exogenous and endogenous hydrogen sulphide in carrageenan-induced knee joint synovitis in the rat

(2010) E Ekundi-Valentim et al.   BRITISH JOURNAL OF PHARMACOLOGY

Epigenetic Mechanisms in Inflammation

(2010) D. Bayarsaihan   JOURNAL OF DENTAL RESEARCH

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Hydrogen sulfide attenuates lipopolysaccharide-induced cognitive impairment: A pro-inflammatory pathway in rats

(2010) Qi-Hai Gong et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

A circadian-regulated gene, Nocturnin, promotes adipogenesis by stimulating PPAR-  nuclear translocation

(2010) M. Kawai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS

Adiponectin may contribute to synovitis and joint destruction in rheumatoid arthritis by stimulating vascular endothelial growth factor, matrix metalloproteinase-1, and matrix metalloproteinase-13 expression in fibroblast-like synoviocytes more than proinflammatory mediators

(2009) Hyun-Mi Choi et al.   ARTHRITIS RESEARCH & THERAPY

IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial

(2008) P. Emery et al.   ANNALS OF THE RHEUMATIC DISEASES

Dual role of hydrogen sulfide in mechanical inflammatory hypernociception

(2008) Thiago M. Cunha et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Regulatory Effects of Hydrogen Sulfide on IL-6, IL-8 and IL-10 Levels in the Plasma and Pulmonary Tissue of Rats with Acute Lung Injury

(2008) Tianshui Li et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Hydrogen Sulfide: A Novel Mediator of Leukocyte Activation

(2008) Huili Zhang et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY