Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease

Plasmatic higher levels of homocysteine in Non-alcoholic fatty liver disease (NAFLD)

(2013) Sylene Coutinho Rampche de Carvalho et al.   Nutrition Journal

Hepatic Methionine Homeostasis Is Conserved in C57BL/6N Mice on High-Fat Diet Despite Major Changes in Hepatic One-Carbon Metabolism

(2013) Christoph Dahlhoff et al.   PLoS One

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Metabolomic Profiling to Identify Predictors of Response to Vitamin E for Non-Alcoholic Steatohepatitis (NASH)

(2012) Jianfeng Cheng et al.   PLoS One

Methionine and protein metabolism in non-alcoholic steatohepatitis: evidence for lower rate of transmethylation of methionine

(2011) Satish C. Kalhan et al.   CLINICAL SCIENCE

Nitric oxide synthases: regulation and function

(2011) U. Forstermann et al.   EUROPEAN HEART JOURNAL

Plasma homocysteine level and hepatic sulfur amino acid metabolism in mice fed a high-fat diet

(2011) Kang Uk Yun et al.   EUROPEAN JOURNAL OF NUTRITION

Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis

(2011) Anabela P. Rolo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Alterations in hepatic one-carbon metabolism and related pathways following a high-fat dietary intervention

(2011) Isabel Rubio-Aliaga et al.   PHYSIOLOGICAL GENOMICS

Betaine improves nonalcoholic fatty liver and associated hepatic insulin resistance: a potential mechanism for hepatoprotection by betaine

(2010) Elango Kathirvel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Role of the Inducible Nitric Oxide Synthase in the Onset of Fructose-Induced Steatosis in Mice

(2010) Astrid Spruss et al.   ANTIOXIDANTS & REDOX SIGNALING

Insulin Resistance in Nonalcoholic Fatty Liver Disease

(2010) E. Bugianesi et al.   CURRENT PHARMACEUTICAL DESIGN

From the metabolic syndrome to NAFLD or vice versa?

(2010) Ester Vanni et al.   DIGESTIVE AND LIVER DISEASE

Inducible Nitric Oxide Distribution in the Fatty Liver of a Mouse with High Fat Diet-Induced Obesity

(2010) Seung-Kwon HA et al.   EXPERIMENTAL ANIMALS

Plasma levels of asymmetric dimethylarginine in patients with biopsy-proven nonalcoholic fatty liver disease

(2010) Takhar Kasumov et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Glycine and urea kinetics in nonalcoholic steatohepatitis in human: effect of intralipid infusion

(2009) Srinivasan Dasarathy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Decreased survival of subjects with elevated liver function tests during a 28-year follow-up

(2009) Cecilia Söderberg et al.   HEPATOLOGY

Homocysteine induces oxidative stress, inflammatory infiltration, fibrosis and reduces glycogen/glycoprotein content in liver of rats

(2009) Cristiane Matté et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Homocysteine Supplementation Attenuates the Unfolded Protein Response in a Murine Nutritional Model of Steatohepatitis

(2009) Anne S. Henkel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-throughput shotgun lipidomics by quadrupole time-of-flight mass spectrometry

(2009) Marcus Ståhlman et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet

(2009) Igor P. Pogribny et al.   JOURNAL OF HEPATOLOGY

Nitric Oxide Plays a Crucial Role in the Development/Progression of Nonalcoholic Steatohepatitis in the Choline-Deficient, l-Amino Acid-Defined Diet-Fed Rat Model

(2008) Koji Fujita et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Methionine Metabolism and Liver Disease

(2008) José M. Mato et al.   Annual Review of Nutrition

Long-Term Follow-Up of Patients With Nonalcoholic Fatty Liver

(2008) Nila Rafiq et al.   Clinical Gastroenterology and Hepatology

Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression

(2008) Onpan Cheung et al.   HEPATOLOGY

DNA methylation determination by liquid chromatography-tandem mass spectrometry using novel biosynthetic [U-15N]deoxycytidine and [U-15N]methyldeoxycytidine internal standards

(2008) E. P. Quinlivan et al.   NUCLEIC ACIDS RESEARCH

Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia

(2008) Goro KIKUCHI et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

The Epidemiology of Nonalcoholic Fatty Liver Disease: A Global Perspective

(2008) Mariana Lazo et al.   SEMINARS IN LIVER DISEASE

DNA digestion to deoxyribonucleoside: A simplified one-step procedure

(2007) Eoin P. Quinlivan et al.   ANALYTICAL BIOCHEMISTRY

Activation and Dysregulation of the Unfolded Protein Response in Nonalcoholic Fatty Liver Disease

(2007) Puneet Puri et al.   GASTROENTEROLOGY