A proof‐of‐concept, Phase 2 clinical trial of the gastrointestinal safety of a hydrogen sulfide‐releasing anti‐inflammatory drug

Hydrogen Sulfide-Releasing Therapeutics: Translation to the Clinic

(2018) John L. Wallace et al.   ANTIOXIDANTS & REDOX SIGNALING

Speciation of Reactive Sulfur Species and their Reactions with Alkylating Agents: Do we have any clue about what is present inside the cell?

(2018) Virág Bogdándi et al.   BRITISH JOURNAL OF PHARMACOLOGY

The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY

(2017) Simon D Harding et al.   NUCLEIC ACIDS RESEARCH

Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis

(2016) Steven E. Nissen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Deciphering the pathogenesis of NSAID enteropathy using proton pump inhibitors and a hydrogen sulfide-releasing NSAID

(2015) Rory W. Blackler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Anti-Inflammatory and Cytoprotective Actions of Hydrogen Sulfide: Translation to Therapeutics

(2015) John L. Wallace et al.   ANTIOXIDANTS & REDOX SIGNALING

A novel orally administered trimebutine compound (GIC-1001) is anti-nociceptive and features peripheral opioid agonistic activity and Hydrogen Sulphide-releasing capacity in mice

(2015) N. Cenac et al.   EUROPEAN JOURNAL OF PAIN

Hydrogen Sulfide Protects from Colitis and Restores Intestinal Microbiota Biofilm and Mucus Production

(2015) Jean-Paul Motta et al.   INFLAMMATORY BOWEL DISEASES

Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter

(2015) John L. Wallace et al.   NATURE REVIEWS DRUG DISCOVERY

Hydrogen sulphide protects against NSAID-enteropathy through modulation of bile and the microbiota

(2014) Rory W Blackler et al.   BRITISH JOURNAL OF PHARMACOLOGY

NSAID-gastroenteropathy: new aspects of pathogenesis and prevention

(2014) Rory W Blackler et al.   CURRENT OPINION IN PHARMACOLOGY

Polypharmacy of Osteoarthritis: The Perfect Intestinal Storm

(2013) John L. Wallace   DIGESTIVE DISEASES AND SCIENCES

Enhanced Synthesis and Diminished Degradation of Hydrogen Sulfide in Experimental Colitis: A Site-Specific, Pro-Resolution Mechanism

(2013) Kyle L. Flannigan et al.   PLoS One

Gas Mediators Involved in Modulating Duodenal HCO3- Secretion

(2012) K. Takeuchi et al.   CURRENT MEDICINAL CHEMISTRY

Gastrointestinal-Sparing Effects of Novel NSAIDs in Rats with Compromised Mucosal Defence

(2012) Rory Blackler et al.   PLoS One

Proton Pump Inhibitors Exacerbate NSAID-Induced Small Intestinal Injury by Inducing Dysbiosis

(2011) John L. Wallace et al.   GASTROENTEROLOGY

Markedly reduced toxicity of a hydrogen sulphide-releasing derivative of naproxen (ATB-346)

(2010) John L Wallace et al.   BRITISH JOURNAL OF PHARMACOLOGY

Treatment of osteoarthritis in hypertensive patients

(2010) Isla S Mackenzie et al.   EXPERT OPINION ON PHARMACOTHERAPY

Time Trends and Impact of Upper and Lower Gastrointestinal Bleeding and Perforation in Clinical Practice

(2009) Angel Lanas et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Endogenous and Exogenous Hydrogen Sulfide Promotes Resolution of Colitis in Rats

(2009) John L. Wallace et al.   GASTROENTEROLOGY

Prostaglandins, NSAIDs, and Gastric Mucosal Protection: Why Doesn't the Stomach Digest Itself?

(2008) John L. Wallace   PHYSIOLOGICAL REVIEWS

Enhanced activity of a hydrogen sulphide-releasing derivative of mesalamine (ATB-429) in a mouse model of colitis

(2007) S Fiorucci et al.   BRITISH JOURNAL OF PHARMACOLOGY