Cardiac H2S Generation Is Reduced in Ageing Diabetic Mice

miRNA-30 Family Inhibition Protects Against Cardiac Ischemic Injury by Regulating Cystathionine-γ-Lyase Expression

(2015) Yaqi Shen et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen sulfide improves glucose metabolism and prevents hypertrophy in cardiomyocytes

(2015) Min Liang et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Functional deficiencies of subsarcolemmal mitochondria in the type 2 diabetic human heart

(2014) Tara L. Croston et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

CaMKKβ-Dependent Activation of AMP-Activated Protein Kinase Is Critical to Suppressive Effects of Hydrogen Sulfide on Neuroinflammation

(2014) Xiaomei Zhou et al.   ANTIOXIDANTS & REDOX SIGNALING

H2S attenuates cognitive deficits through Akt1/JNK3 signaling pathway in ischemic stroke

(2014) Xiangru Wen et al.   BEHAVIOURAL BRAIN RESEARCH

Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition

(2014) Mariarosaria Bucci et al.   CARDIOVASCULAR RESEARCH

Hyperhomocysteinemia Potentiates Hyperglycemia-Induced Inflammatory Monocyte Differentiation and Atherosclerosis

(2014) P. Fang et al.   DIABETES

Inhibition of JNK Phosphorylation by a Novel Curcumin Analog Prevents High Glucose-Induced Inflammation and Apoptosis in Cardiomyocytes and the Development of Diabetic Cardiomyopathy

(2014) Y. Pan et al.   DIABETES

Dietary Sugar and Body Weight: Have We Reached a Crisis in the Epidemic of Obesity and Diabetes?

(2014) George A. Bray et al.   DIABETES CARE

Hydrogen sulfide protected gastric epithelial cell from ischemia/reperfusion injury by Keap1 s-sulfhydration, MAPK dependent anti-apoptosis and NF-κB dependent anti-inflammation pathway

(2014) Cheng Guo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Targeting hydrogen sulfide as a promising therapeutic strategy for atherosclerosis

(2014) Suowen Xu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Decreased Cystathionine-γ-lyase (CSE) Activity in Livers of Type 1 Diabetic Rats and Peripheral Blood Mononuclear Cells (PBMC) of Type 1 Diabetic Patients

(2014) Prasenjit Manna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol-enhanced autophagic flux ameliorates myocardial oxidative stress injury in diabetic mice

(2014) Bo Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede development of diabetic cardiomyopathy are prevented by resveratrol in ZDF rats

(2014) Marie-Soleil Beaudoin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent

(2014) A. L. King et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exendin-4 attenuates high glucose-induced cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and activation of SERCA2a

(2013) Craig W. Younce et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hydrogen sulfide deficiency and diabetic renal remodeling: role of matrix metalloproteinase-9

(2013) Sourav Kundu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glucagon-like peptide-1 receptor activation reverses cardiac remodeling via normalizing cardiac steatosis and oxidative stress in type 2 diabetes

(2013) Akio Monji et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Apelin gene therapy increases myocardial vascular density and ameliorates diabetic cardiomyopathy via upregulation of sirtuin 3

(2013) Heng Zeng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hypoxia-inducible factors regulate human and rat cystathionine β-synthase gene expression

(2013) Naoharu Takano et al.   BIOCHEMICAL JOURNAL

Sugar, Uric Acid, and the Etiology of Diabetes and Obesity

(2013) R. J. Johnson et al.   DIABETES

Promoted Interaction of Nuclear Factor- B with Demethylated Cystathionine- -Synthetase Gene Contributes to Gastric Hypersensitivity in Diabetic Rats

(2013) H.-H. Zhang et al.   JOURNAL OF NEUROSCIENCE

Cystathionine  -Lyase Protects against Renal Ischemia/Reperfusion by Modulating Oxidative Stress

(2013) E. M. Bos et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells

(2013) Norihiro Shibuya et al.   Nature Communications

Heart angiotensin II-induced cardiomyocyte hypertrophy suppresses coronary angiogenesis and progresses diabetic cardiomyopathy

(2012) Takahiro Masuda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

In African American Type 2 Diabetic Patients, Is Vitamin D Deficiency Associated with Lower Blood Levels of Hydrogen Sulfide and Cyclic Adenosine Monophosphate, and Elevated Oxidative Stress?

(2012) Sushil K. Jain et al.   ANTIOXIDANTS & REDOX SIGNALING

Distribution of hydrogen sulfide (H2S)-producing enzymes and the roles of the H2S donor sodium hydrosulfide in diabetic nephropathy

(2012) Junichiro Yamamoto et al.   Clinical and Experimental Nephrology

Grape Polyphenols Prevent Fructose-Induced Oxidative Stress and Insulin Resistance in First-Degree Relatives of Type 2 Diabetic Patients

(2012) M. Hokayem et al.   DIABETES CARE

Exogenous hydrogen sulfide attenuates diabetic myocardial injury through cardiac mitochondrial protection

(2012) Xin Zhong et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Promoter demethylation of cystathionine-β-synthetase gene contributes to inflammatory pain in rats

(2012) Feihu Qi et al.   PAIN

The Pathogenic Role of Cystathionine γ-Lyase/Hydrogen Sulfide in Streptozotocin-Induced Diabetes in Mice

(2011) Guangdong Yang et al.   AMERICAN JOURNAL OF PATHOLOGY

The Quantitative Significance of the Transsulfuration Enzymes for H2S Production in Murine Tissues

(2011) Omer Kabil et al.   ANTIOXIDANTS & REDOX SIGNALING

Rat pancreatic level of cystathionine γ-lyase is regulated by glucose level via specificity protein 1 (SP1) phosphorylation

(2011) L. Zhang et al.   DIABETOLOGIA

Measurement of plasma hydrogen sulfide in vivo and in vitro

(2011) Xinggui Shen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hydrogen Sulfide Inhibits High Glucose-induced Matrix Protein Synthesis by Activating AMP-activated Protein Kinase in Renal Epithelial Cells

(2011) Hak Joo Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function

(2011) K. Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen sulfide protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis by preventing GSK-3β-dependent opening of mPTP

(2010) Ling-Ling Yao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Low Levels of Hydrogen Sulfide in the Blood of Diabetes Patients and Streptozotocin-Treated Rats Causes Vascular Inflammation?

(2010) Sushil K. Jain et al.   ANTIOXIDANTS & REDOX SIGNALING

Adiposity is a major determinant of plasma levels of the novel vasodilator hydrogen sulphide

(2010) M. Whiteman et al.   DIABETOLOGIA

The Hydrogen Sulfide Donor NaHS Promotes Angiogenesis in a Rat Model of Hind Limb Ischemia

(2009) Ming-Jie Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Interval Training Normalizes Cardiomyocyte Function, Diastolic Ca 2+ Control, and SR Ca 2+ Release Synchronicity in a Mouse Model of Diabetic Cardiomyopathy

(2009) Tomas O. Stølen et al.   CIRCULATION RESEARCH

Hypothesis: Could Excessive Fructose Intake and Uric Acid Cause Type 2 Diabetes?

(2009) Richard J. Johnson et al.   ENDOCRINE REVIEWS

Blockage of receptor for advanced glycation end products prevents development of cardiac dysfunction in db/db type 2 diabetic mice

(2009) Jan M. Nielsen et al.   EUROPEAN JOURNAL OF HEART FAILURE

Vascular Endothelium Expresses 3-Mercaptopyruvate Sulfurtransferase and Produces Hydrogen Sulfide

(2009) N. Shibuya et al.   JOURNAL OF BIOCHEMISTRY

H2S Biogenesis by Human Cystathionine γ-Lyase Leads to the Novel Sulfur Metabolites Lanthionine and Homolanthionine and Is Responsive to the Grade of Hyperhomocysteinemia

(2009) Taurai Chiku et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Relative Contributions of Cystathionine β-Synthase and γ-Cystathionase to H2S Biogenesis via Alternative Trans-sulfuration Reactions

(2009) Sangita Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conditional increase in SERCA2a protein is able to reverse contractile dysfunction and abnormal calcium flux in established diabetic cardiomyopathy

(2008) Jorge Suarez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Biosynthesis of H2S is impaired in non-obese diabetic (NOD) mice

(2008) V Brancaleone et al.   BRITISH JOURNAL OF PHARMACOLOGY

Glucose-induced production of hydrogen sulfide may protect the pancreatic beta-cells from apoptotic cell death by high glucose

(2008) Yukiko Kaneko et al.   FEBS LETTERS