Melatonin: Regulation of Biomolecular Condensates in Neurodegenerative Disorders

Biomolecular condensates and cancer

(2021) Ann Boija et al.   CANCER CELL

Melatonin synthesis in and uptake by mitochondria: implications for diseased cells with dysfunctional mitochondria

(2021) Russel J Reiter et al.   Future Medicinal Chemistry

Cholesterol and Sphingolipid Enriched Lipid Rafts as Therapeutic Targets in Cancer

(2021) Michela Codini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anti-Warburg Effect of Melatonin: A Proposed Mechanism to Explain its Inhibition of Multiple Diseases

(2021) Russel J. Reiter et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Barth syndrome: cardiolipin, cellular pathophysiology, management, and novel therapeutic targets

(2021) Hana M. Zegallai et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

mRNA translation in stress granules is not uncommon

(2021) Kim Baumann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FUS and TDP-43 Phases in Health and Disease

(2021) Bede Portz et al.   TRENDS IN BIOCHEMICAL SCIENCES

Global non-covalent SUMO interaction networks reveal SUMO-dependent stabilization of the non-homologous end joining complex

(2021) Román González-Prieto et al.   Cell Reports

Cardiolipin content controls mitochondrial coupling and energetic efficiency in muscle

(2021) Alexandre Prola et al.   Science Advances

The Implications of PDK1–4 on Tumor Energy Metabolism, Aggressiveness and Therapy Resistance

(2021) Emine Atas et al.   Frontiers in Oncology

Stress Granules in the Post-transcriptional Regulation of Immune Cells

(2021) Nicolas Curdy et al.   Frontiers in Cell and Developmental Biology

Lipid Peroxidation Enhances LO/LD Domain Phase Separation in Giant Plasma Membrane Vesicles

(2021) Muthuraj Balakrishnan et al.   BIOPHYSICAL JOURNAL

Aberrant phase separation and cancer

(2021) Kenzui Taniue et al.   FEBS Journal

The Participation of the Intrinsically Disordered Regions of the bHLH-PAS Transcription Factors in Disease Development

(2021) Marta Kolonko-Adamska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cofactors are Remnants of Life’s Origin and Early Evolution

(2021) Aaron D. Goldman et al.   JOURNAL OF MOLECULAR EVOLUTION

SUMO and Transcriptional Regulation: The Lessons of Large-Scale Proteomic, Modifomic and Genomic Studies

(2021) Mathias Boulanger et al.   MOLECULES

SUMOylation of YTHDF2 promotes mRNA degradation and cancer progression by increasing its binding affinity with m6A-modified mRNAs

(2021) Guofang Hou et al.   NUCLEIC ACIDS RESEARCH

TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau

(2021) Peter E. A. Ash et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes

(2021) Tobias E. Spikes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane-associated phase separation: organization and function emerge from a two-dimensional milieu

(2021) Jonathon A Ditlev   Journal of Molecular Cell Biology

Interactions between Phase-Separated Liquids and Membrane Surfaces

(2021) Samuel Botterbusch et al.   Applied Sciences-Basel

SUMOylation Connects Cell Stress Responses and Inflammatory Control: Lessons From the Gut as a Model Organ

(2021) Jörn Karhausen et al.   Frontiers in Immunology

Light-Dependent Translation Change of Arabidopsis psbA Correlates with RNA Structure Alterations at the Translation Initiation Region

(2021) Piotr Gawroński et al.   Cells

Tellurite Promotes Stress Granules and Nuclear SG-Like Assembly in Response to Oxidative Stress and DNA Damage

(2021) Aracelly Gaete-Argel et al.   Frontiers in Cell and Developmental Biology

Dr. Jekyll and Mr. Hyde? Physiology and Pathology of Neuronal Stress Granules

(2021) Pureum Jeon et al.   Frontiers in Cell and Developmental Biology

Valency and Binding Affinity Variations Can Regulate the Multilayered Organization of Protein Condensates with Many Components

(2021) Ignacio Sanchez-Burgos et al.   Biomolecules

The Role of Cardiolipin as a Scaffold Mitochondrial Phospholipid in Autophagosome Formation: In Vitro Evidence

(2021) Valeria Manganelli et al.   Biomolecules

ER Stress-Sensor Proteins and ER-Mitochondrial Crosstalk—Signaling Beyond (ER) Stress Response

(2021) Vaishali Kumar et al.   Biomolecules

Mitochondrial Lipid Signaling and Adaptive Thermogenesis

(2021) Helaina Von Bank et al.   Metabolites

Primitive Compartmentalization for the Sustainable Replication of Genetic Molecules

(2021) Ryo Mizuuchi et al.   Life-Basel

Comparative profiling of stress granule clearance reveals differential contributions of the ubiquitin system

(2021) Nazife Tolay et al.   Life Science Alliance

The key role of solvent in condensation: Mapping water in liquid-liquid phase-separated FUS

(2021) Jonas Ahlers et al.   BIOPHYSICAL JOURNAL

Biomolecular condensates in membrane receptor signaling

(2021) Khuloud Jaqaman et al.   CURRENT OPINION IN CELL BIOLOGY

Interplay of RNA-Binding Proteins and microRNAs in Neurodegenerative Diseases

(2021) Chisato Kinoshita et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adenosine triphosphate energy‐independently controls protein homeostasis with unique structure and diverse mechanisms

(2021) Jianxing Song   PROTEIN SCIENCE

Liquid–liquid phase separation of tau: From molecular biophysics to physiology and disease

(2021) Sandeep K. Rai et al.   PROTEIN SCIENCE

Cardiolipin, Mitochondria, and Neurological Disease

(2021) Micol Falabella et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Role of Proteasomes in Inflammation

(2021) Carl Christoph Goetzke et al.   Journal of Clinical Medicine

Role of RNA N6-Methyladenosine Modification in Male Infertility and Genital System Tumors

(2021) Shuai Liu et al.   Frontiers in Cell and Developmental Biology

The Integral Role of RNA in Stress Granule Formation and Function

(2021) Danae Campos-Melo et al.   Frontiers in Cell and Developmental Biology

SUMO: Glue or Solvent for Phase-Separated Ribonucleoprotein Complexes and Molecular Condensates?

(2021) Jan Keiten-Schmitz et al.   Frontiers in Molecular Biosciences

An Emerging Role for Post-translational Modifications in Regulating RNP Condensates in the Germ Line

(2021) Jennifer A. Schisa et al.   Frontiers in Molecular Biosciences

Time-resolved comparative molecular evolution of oxygenic photosynthesis

(2021) Thomas Oliver et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mechanistic Insights on ATP’s Role as a Hydrotrope

(2021) Susmita Sarkar et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Melatonin inhibits lung cancer development by reversing the Warburg effect via stimulating the SIRT3/PDH axis

(2021) Xiangyun Chen et al.   JOURNAL OF PINEAL RESEARCH

Potential roles of N6-methyladenosine (m6A) in immune cells

(2021) Chang Liu et al.   Journal of Translational Medicine

Melatonin, Its Metabolites and Their Interference with Reactive Nitrogen Compounds

(2021) Rüdiger Hardeland   MOLECULES

The Nuclear Pore Complex as a Transcription Regulator

(2021) Michael Chas Sumner et al.   Cold Spring Harbor Perspectives in Biology

Mitochondrial Targeting Involving Cholesterol-Rich Lipid Rafts in the Mechanism of Action of the Antitumor Ether Lipid and Alkylphospholipid Analog Edelfosine

(2021) Faustino Mollinedo et al.   Pharmaceutics

TDP-43 Mutation Affects Stress Granule Dynamics in Differentiated NSC-34 Motoneuron-Like Cells

(2021) Qiao Ding et al.   Frontiers in Cell and Developmental Biology

Emerging Roles of Liquid–Liquid Phase Separation in Cancer: From Protein Aggregation to Immune-Associated Signaling

(2021) Jiahua Lu et al.   Frontiers in Cell and Developmental Biology

Melatonin Attenuates Chromium (VI)-Induced Spermatogonial Stem Cell/Progenitor Mitophagy by Restoration of METTL3-Mediated RNA N6-Methyladenosine Modification

(2021) Yinghua Lv et al.   Frontiers in Cell and Developmental Biology

Stress Granule-Mediated Oxidized RNA Decay in P-Body: Hypothetical Role of ADAR1, Tudor-SN, and STAU1

(2021) Ravi Kumar Alluri et al.   Frontiers in Molecular Biosciences

ATP biphasically modulates LLPS of TDP-43 PLD by specifically binding arginine residues

(2021) Mei Dang et al.   Communications Biology

Transcriptome and N6-Methyladenosine RNA Methylome Analyses in Aortic Dissection and Normal Human Aorta

(2021) Xianwu Zhou et al.   Frontiers in Cardiovascular Medicine

RNA and liquid-liquid phase separation

(2021) Qi Guo et al.   Non-coding RNA Research

Electrostatically Driven Complex Coacervation and Amyloid Aggregation of Tau Are Independent Processes with Overlapping Conditions

(2020) Yanxian Lin et al.   ACS Chemical Neuroscience

Familial globular glial tauopathy linked to MAPT mutations: molecular neuropathology and seeding capacity of a prototypical mixed neuronal and glial tauopathy

(2020) Isidro Ferrer et al.   ACTA NEUROPATHOLOGICA

Modulation of RNA Condensation by the DEAD-Box Protein eIF4A

(2020) Devin Tauber et al.   CELL

Melatonin inhibits Warburg-dependent cancer by redirecting glucose oxidation to the mitochondria: a mechanistic hypothesis

(2020) Russel J. Reiter et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dbp5/DDX19 between Translational Readthrough and Nonsense Mediated Decay

(2020) Christian Beißel et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mass spectrometric investigation of cardiolipins and their oxidation products after two-dimensional heart-cut liquid chromatography

(2020) Patrick O. Helmer et al.   JOURNAL OF CHROMATOGRAPHY A

Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapy

(2020) Faustino Mollinedo et al.   JOURNAL OF LIPID RESEARCH

Stress- and ubiquitylation-dependent phase separation of the proteasome

(2020) Sayaka Yasuda et al.   NATURE

Exploring the interplay between fibrillization and amorphous aggregation channels on the energy landscapes of tau repeat isoforms

(2020) Xun Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TDP-43 α-helical structure tunes liquid–liquid phase separation and function

(2020) Alexander E. Conicella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synonymous codon substitutions perturb cotranslational protein folding in vivo and impair cell fitness

(2020) Ian M. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons

(2020) Kazuhide Asakawa et al.   Nature Communications

Liquid-like droplet formation by tumor suppressor p53 induced by multivalent electrostatic interactions between two disordered domains

(2020) Kiyoto Kamagata et al.   Scientific Reports

Abnormality of m6A mRNA Methylation Is Involved in Alzheimer’s Disease

(2020) Min Han et al.   Frontiers in Neuroscience

Cardiolipin Structure and Oxidation Are Affected by Ca2+ at the Interface of Lipid Bilayers

(2020) Érica G. A. Miranda et al.   Frontiers in Chemistry

Melatonin Inhibits Formation of Mitochondrial Permeability Transition Pores and Improves Oxidative Phosphorylation of Frozen-Thawed Ram Sperm

(2020) Yi Fang et al.   Frontiers in Endocrinology

Alternative Mechanisms of p53 Action During the Unfolded Protein Response

(2020) Leïla T. S. Fusée et al.   Cancers

RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia

(2020) Chao Shen et al.   Cell Stem Cell

SUMOylation in development and neurodegeneration

(2020) Tak-Yu Yau et al.   DEVELOPMENT

DDX3X Sits at the Crossroads of Liquid–Liquid and Prionoid Phase Transitions Arbitrating Life and Death Cell Fate Decisions in Stressed Cells

(2020) Parimal Samir et al.   DNA AND CELL BIOLOGY

The emerging role of RNA modifications in the regulation of mRNA stability

(2020) Sung Ho Boo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Properties of Lipid Rafts in Two Epigenetically Distinct Subtypes of the Oncogenic Cell‐line SW13

(2020) Agnes S. Pascual et al.   FASEB JOURNAL

Sumoylation on its 25th anniversary: mechanisms, pathology, and emerging concepts

(2020) Arda B. Celen et al.   FEBS Journal

Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- and lipid-binding properties of Tau

(2020) Nadine Ait-Bouziad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid rafts as a therapeutic target

(2020) Dmitri Sviridov et al.   JOURNAL OF LIPID RESEARCH

Melatonin restores the pluripotency of long‐term‐cultured embryonic stem cells through melatonin receptor‐dependent m6A RNA regulation

(2020) Lei Yang et al.   JOURNAL OF PINEAL RESEARCH

Molecular Picture of the Transient Nature of Lipid Rafts

(2020) Dima Bolmatov et al.   LANGMUIR

Phase separation directs ubiquitination of gene-body nucleosomes

(2020) Laura D. Gallego et al.   NATURE

m6A-binding YTHDF proteins promote stress granule formation

(2020) Ye Fu et al.   Nature Chemical Biology

Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior

(2020) Benjamin S. Schuster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GSK3β and Tau Protein in Alzheimer’s Disease and Epilepsy

(2020) Danira Toral-Rios et al.   Frontiers in Cellular Neuroscience

The unprecedented membrane deformation of the human nuclear envelope, in a magnetic field, indicates formation of nuclear membrane invaginations

(2020) Régine Dazzoni et al.   Scientific Reports

Phase‐separated bacterial ribonucleoprotein bodies organize mRNA decay

(2020) Nisansala S. Muthunayake et al.   Wiley Interdisciplinary Reviews-RNA

RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia

(2020) Gregory G Fuller et al.   eLife

Effects of Light Quality and Phytochrome Form on Melatonin Biosynthesis in Rice

(2020) Ok Jin Hwang et al.   Biomolecules

Synthesis of a New Water-Soluble Melatonin Derivative with Low Toxicity and a Strong Effect on Sleep Aid

(2020) Jianghong Zhang et al.   ACS Omega

The physiological roles of tau and Aβ: implications for Alzheimer’s disease pathology and therapeutics

(2020) Sarah A. Kent et al.   ACTA NEUROPATHOLOGICA

The biological function of m6A demethylase ALKBH5 and its role in human disease

(2020) Jinyan Wang et al.   Cancer Cell International

Stress granule subtypes: an emerging link to neurodegeneration

(2020) Vivek M. Advani et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Hydroxyl radical scavenging activity of melatonin and its related indolamines

(2020) Aiswarya Purushothaman et al.   FREE RADICAL RESEARCH

m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development

(2020) Yimeng Gao et al.   IMMUNITY

Effect of Melatonin on Tau aggregation and Tau-mediated cell surface morphology

(2020) Rashmi Das et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

SUMOylation-Mediated Response to Mitochondrial Stress

(2020) Jianli He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis

(2020) Richard G. Lee et al.   JOURNAL OF CELL SCIENCE

Switching Diseased Cells from Cytosolic Aerobic Glycolysis to Mitochondrial Oxidative Phosphorylation: A Metabolic Rhythm Regulated by Melatonin?

(2020) Russel J. Reiter et al.   JOURNAL OF PINEAL RESEARCH

Lipid and protein dynamics that shape nuclear envelope identity

(2020) Shirin Bahmanyar et al.   MOLECULAR BIOLOGY OF THE CELL

The Nuclear SUMO-Targeted Ubiquitin Quality Control Network Regulates the Dynamics of Cytoplasmic Stress Granules

(2020) Jan Keiten-Schmitz et al.   MOLECULAR CELL

ATP-Driven Separation of Liquid Phase Condensates in Bacteria

(2020) Baptiste Guilhas et al.   MOLECULAR CELL

α-Synuclein aggregation nucleates through liquid–liquid phase separation

(2020) Soumik Ray et al.   Nature Chemistry

RNA contributions to the form and function of biomolecular condensates

(2020) Christine Roden et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

E2F1 sumoylation as a protective cellular mechanism in oxidative stress response

(2020) Joshua D. Graves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hotspot mutant p53-R273H inhibits KLF6 expression to promote cell migration and tumor metastasis

(2020) Shengnan Sun et al.   Cell Death & Disease

Liquid-liquid phase separation induces pathogenic tau conformations in vitro

(2020) Nicholas M. Kanaan et al.   Nature Communications

Lipid membrane templated misfolding and self-assembly of intrinsically disordered tau protein

(2020) Jaroslaw Majewski et al.   Scientific Reports

Reduced free ubiquitin levels and proteasome activity in cultured neurons and brain tissues treated with amyloid beta aggregates

(2020) Chul-Woo Park et al.   Molecular Brain

P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer’s disease

(2020) Kathleen M. Farmer et al.   Acta Neuropathologica Communications

Roles of N6-Methyladenosine (m6A) in Stem Cell Fate Decisions and Early Embryonic Development in Mammals

(2020) Meng Zhang et al.   Frontiers in Cell and Developmental Biology

Key Mechanisms and Potential Targets of the NLRP3 Inflammasome in Neurodegenerative Diseases

(2020) Yadi Guan et al.   Frontiers in Integrative Neuroscience

Tau affects P53 function and cell fate during the DNA damage response

(2020) Martina Sola et al.   Communications Biology

ATP Kinetically Modulates Pathogenic Tau Fibrillations

(2020) Chae Eun Heo et al.   ACS Chemical Neuroscience

The emergence of phase separation as an organizing principle in bacteria

(2020) Christopher A. Azaldegui et al.   BIOPHYSICAL JOURNAL

Coupled Membrane Lipid Miscibility and Phosphotyrosine-Driven Protein Condensation Phase Transitions

(2020) Jean K. Chung et al.   BIOPHYSICAL JOURNAL

Mechanisms of epitranscriptomic gene regulation

(2020) Kyung W. Seo et al.   BIOPOLYMERS

Rafting Down the Metastatic Cascade: The Role of Lipid Rafts in Cancer Metastasis, Cell Death, and Clinical Outcomes

(2020) Joshua D. Greenlee et al.   CANCER RESEARCH

Lateral heterogeneity and domain formation in cellular membranes

(2020) Jacob J. Kinnun et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Phase Separation and Neurodegenerative Diseases: A Disturbance in the Force

(2020) Aurélie Zbinden et al.   DEVELOPMENTAL CELL

Melatonin Induction of APP Intracellular Domain 50 SUMOylation Alleviates AD through Enhanced Transcriptional Activation and Aβ Degradation

(2020) Yen-Chen Liu et al.   MOLECULAR THERAPY

Nucleated transcriptional condensates amplify gene expression

(2020) Ming-Tzo Wei et al.   NATURE CELL BIOLOGY

Cristae Membrane Dynamics – A Paradigm Change

(2020) Arun Kumar Kondadi et al.   TRENDS IN CELL BIOLOGY

ATP hydrolysis by yeast Hsp104 determines protein aggregate dissolution and size in vivo

(2020) Udhayabhaskar Sathyanarayanan et al.   Nature Communications

Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions

(2020) Mengyu Liu et al.   Scientific Reports

Daily Cycles of Reversible Protein Condensation in Cyanobacteria

(2020) Gopal K. Pattanayak et al.   Cell Reports

Neuronal Signaling Involved in Neuronal Polarization and Growth: Lipid Rafts and Phosphorylation

(2020) Michihiro Igarashi et al.   Frontiers in Molecular Neuroscience

Interaction of Alpha-Synuclein With Lipids: Mitochondrial Cardiolipin as a Critical Player in the Pathogenesis of Parkinson’s Disease

(2020) Valentina Gilmozzi et al.   Frontiers in Neuroscience

Ubiquitin, Autophagy and Neurodegenerative Diseases

(2020) Yoshihisa Watanabe et al.   Cells

Free-Radical-Mediated Formation of Trans-Cardiolipin Isomers, Analytical Approaches for Lipidomics and Consequences of the Structural Organization of Membranes

(2020) Fabrizio Vetica et al.   Biomolecules

Altered Expression of the m6A Methyltransferase METTL3 in Alzheimer’s Disease

(2020) He Huang et al.   eNeuro

From start to end: Phase separation and transcriptional regulation

(2020) Liu Peng et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Melatonin regulates Aβ production/clearance balance and Aβ neurotoxicity: A potential therapeutic molecule for Alzheimer’s disease

(2020) Yuanming Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Melatonin Alters Fluid Phase Coexistence in POPC/DPPC/Cholesterol Membranes

(2020) Nanqin Mei et al.   BIOPHYSICAL JOURNAL

Phase Separation as a Missing Mechanism for Interpretation of Disease Mutations

(2020) Brian Tsang et al.   CELL

RNA-Mediated Feedback Control of Transcriptional Condensates

(2020) Jonathan E. Henninger et al.   CELL

Single-Molecule Imaging Reveals Translation of mRNAs Localized to Stress Granules

(2020) Daniel Mateju et al.   CELL

Peripheral Glycolysis in Neurodegenerative Diseases

(2020) Simon M. Bell et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Liquid-Liquid Phase Separation of Tau Driven by Hydrophobic Interaction Facilitates Fibrillization of Tau

(2020) Yanxian Lin et al.   JOURNAL OF MOLECULAR BIOLOGY

Gene regulation by long non-coding RNAs and its biological functions

(2020) Luisa Statello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Widespread occurrence of the droplet state of proteins in the human proteome

(2020) Maarten Hardenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory mechanisms of tau protein fibrillation under the conditions of liquid–liquid phase separation

(2020) Solomiia Boyko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The pleiotropic role of p53 in functional/dysfunctional neurons: focus on pathogenesis and diagnosis of Alzheimer’s disease

(2020) Giulia Abate et al.   Alzheimers Research & Therapy

Complex Interactions Between Membrane-Bound Organelles, Biomolecular Condensates and the Cytoskeleton

(2020) Max Koppers et al.   Frontiers in Cell and Developmental Biology

Tumor suppressor protein p53 expressed in yeast can remain diffuse, form a prion, or form unstable liquid-like droplets

(2020) Sei-Kyoung Park et al.   iScience

Biomolecular condensates as arbiters of biochemical reactions inside the nucleus

(2020) Guillaume Laflamme et al.   Communications Biology

The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier

(2019) Jonathan J. Ruprecht et al.   CELL

Melatonin in macrophage biology: Current understanding and future perspectives

(2019) Yaoyao Xia et al.   JOURNAL OF PINEAL RESEARCH

Melatonin receptor stimulation by agomelatine prevents Aβ-induced tau phosphorylation and oxidative damage in PC12 cells

(2019) Kai Yao et al.   Drug Design Development and Therapy

Pathogenic alpha-synuclein aggregates preferentially bind to mitochondria and affect cellular respiration

(2019) Xinhe Wang et al.   Acta Neuropathologica Communications

Pathological Tau From Alzheimer’s Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo

(2019) Jin Miao et al.   Frontiers in Aging Neuroscience

Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

(2019) Sindhuja Sridharan et al.   Nature Communications

Coming together to define membrane contact sites

(2019) Luca Scorrano et al.   Nature Communications

A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS

(2019) William Y. C. Huang et al.   SCIENCE

Stoichiometry controls activity of phase-separated clusters of actin signaling proteins

(2019) Lindsay B. Case et al.   SCIENCE

Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows

(2019) Thorsten B. Blum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The p53 mRNA: an integral part of the cellular stress response

(2019) Lucia Haronikova et al.   NUCLEIC ACIDS RESEARCH

RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43

(2019) Jacob R. Mann et al.   NEURON

Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death

(2019) Fatima Gasset-Rosa et al.   NEURON

Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells

(2019) Dali Han et al.   NATURE

Rubisco condensate formation by CcmM in β-carboxysome biogenesis

(2019) H. Wang et al.   NATURE

RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3

(2019) Yi Niu et al.   Molecular Cancer

Double bonds of unsaturated fatty acids differentially regulate mitochondrial cardiolipin remodeling

(2019) Hsiu-Chi Ting et al.   Lipids in Health and Disease

Matter over mind: Liquid phase separation and neurodegeneration

(2019) Shana Elbaum-Garfinkle   JOURNAL OF BIOLOGICAL CHEMISTRY

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

(2019) Simon Alberti et al.   CELL

The Critical Role of RNA m6A Methylation in Cancer

(2019) Qing Lan et al.   CANCER RESEARCH

Down-Regulation of m6A mRNA Methylation Is Involved in Dopaminergic Neuronal Death

(2019) Xuechai Chen et al.   ACS Chemical Neuroscience

The role of m6A RNA methylation in cancer

(2019) Ting Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Chemical Basis of Reactive Oxygen Species Reactivity and Involvement in Neurodegenerative Diseases

(2019) Fabrice Collin   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Liquid-liquid phase separation of tau protein: The crucial role of electrostatic interactions

(2019) Solomiia Boyko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological doses of melatonin impede cognitive decline in tau‐related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux

(2019) Enrique Luengo et al.   JOURNAL OF PINEAL RESEARCH

Prebiotic phosphorylation of 2-thiouridine provides either nucleotides or DNA building blocks via photoreduction

(2019) Jianfeng Xu et al.   Nature Chemistry

Active Protein Neddylation or Ubiquitylation Is Dispensable for Stress Granule Dynamics

(2019) Sebastian Markmiller et al.   Cell Reports

Narrow equilibrium window for complex coacervation of tau and RNA under cellular conditions

(2019) Yanxian Lin et al.   eLife

Structure of a bacterial ATP synthase

(2019) Hui Guo et al.   eLife

Lipidomic Alterations in the Mitochondria of Aged Parkin Null Mice Relevant to Autophagy

(2019) Angel Gaudioso et al.   Frontiers in Neuroscience

m6A Regulates Neurogenesis and Neuronal Development by Modulating Histone Methyltransferase Ezh2

(2019) Junchen Chen et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Cardiolipin Promotes Pore-Forming Activity of Alpha-Synuclein Oligomers in Mitochondrial Membranes

(2019) Stephanie Ghio et al.   ACS Chemical Neuroscience

Cardiolipin-Dependent Properties of Model Mitochondrial Membranes from Molecular Simulations

(2019) Blake A. Wilson et al.   BIOPHYSICAL JOURNAL

Phase separation of 53 BP 1 determines liquid‐like behavior of DNA repair compartments

(2019) Sinan Kilic et al.   EMBO JOURNAL

Detection of brain specific cardiolipins in plasma after experimental pediatric head injury

(2019) Tamil S. Anthonymuthu et al.   EXPERIMENTAL NEUROLOGY

Insights into the Role of P-Bodies and Stress Granules in Protein Quality Control

(2019) Regina Nostramo et al.   GENETICS

Examination of the associations between m6A-associated single-nucleotide polymorphisms and blood pressure

(2019) Xing-Bo Mo et al.   HYPERTENSION RESEARCH

Inhibiting ubiquitination causes an accumulation of SUMOylated newly synthesized nuclear proteins at PML bodies

(2019) Zhe Sha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanics of nuclear membranes

(2019) Ashutosh Agrawal et al.   JOURNAL OF CELL SCIENCE

Evidence for ATP Interaction with Phosphatidylcholine Bilayers

(2019) Alvaro Garcia et al.   LANGMUIR

Exploring the links between lipid geometry and mitochondrial fission: Emerging concepts

(2019) Ashutosh Agrawal et al.   MITOCHONDRION

Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome

(2019) Humayun Sharif et al.   NATURE

m6A enhances the phase separation potential of mRNA

(2019) Ryan J. Ries et al.   NATURE

In vitro 0N4R tau fibrils contain a monomorphic β-sheet core enclosed by dynamically heterogeneous fuzzy coat segments

(2019) Aurelio J. Dregni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer’s Disease as a Membrane Disorder: Spatial Cross-Talk Among Beta-Amyloid Peptides, Nicotinic Acetylcholine Receptors and Lipid Rafts

(2019) Camila Fabiani et al.   Frontiers in Cellular Neuroscience

m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade

(2019) Seungwon Yang et al.   Nature Communications

RNA is a critical element for the sizing and the composition of phase-separated RNA–protein condensates

(2019) Marina Garcia-Jove Navarro et al.   Nature Communications

RNA structure drives interaction with proteins

(2019) Natalia Sanchez de Groot et al.   Nature Communications

The mechanism of RNA duplex recognition and unwinding by DEAD-box helicase DDX3X

(2019) He Song et al.   Nature Communications

FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export

(2019) Brittany M. Edens et al.   Cell Reports

Melatonin Attenuates LPS-Induced Acute Depressive-Like Behaviors and Microglial NLRP3 Inflammasome Activation Through the SIRT1/Nrf2 Pathway

(2019) Burak I. Arioz et al.   Frontiers in Immunology

Melatonin: Clinical Perspectives in Neurodegeneration

(2019) Daniel P. Cardinali   Frontiers in Endocrinology

Lipid Raft Phase Modulation by Membrane-Anchored Proteins with Inherent Phase Separation Properties

(2019) Il-Hyung Lee et al.   ACS Omega

Competitive electrochemical immunosensor for the detection of unfolded p53 protein in blood as biomarker for Alzheimer’s disease

(2019) Olaya Amor-Gutiérrez et al.   ANALYTICA CHIMICA ACTA

Liquid–Liquid Phase Separation in Disease

(2019) Simon Alberti et al.   Annual Review of Genetics

The role of MDM2 amplification and overexpression in therapeutic resistance of malignant tumors

(2019) Helei Hou et al.   Cancer Cell International

Multivalent m6A motifs promote phase separation of YTHDF proteins

(2019) Yifei Gao et al.   CELL RESEARCH

Lipid and Lipid Raft Alteration in Aging and Neurodegenerative Diseases: A Window for the Development of New Biomarkers

(2019) Mesa-Herrera et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Deciphering Melatonin-Stabilized Phase Separation in Phospholipid Bilayers

(2019) Dima Bolmatov et al.   LANGMUIR

Enhancer Features that Drive Formation of Transcriptional Condensates

(2019) Krishna Shrinivas et al.   MOLECULAR CELL

Organization and regulation of gene transcription

(2019) Patrick Cramer   NATURE

DEAD-box ATPases are global regulators of phase-separated organelles

(2019) Maria Hondele et al.   NATURE

Computational identification of key genes that may regulate gene expression reprogramming in Alzheimer’s patients

(2019) Judith A. Potashkin et al.   PLoS One

Novel Functions of the Neurodegenerative-Related Gene Tau in Cancer

(2019) Ricardo Gargini et al.   Frontiers in Aging Neuroscience

Membrane-Bound Meet Membraneless in Health and Disease

(2019) Chujun Zhang et al.   Cells

ATP is a cryptic binder of TDP-43 RRM domains to enhance stability and inhibit ALS/AD-associated fibrillation

(2019) Mei Dang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prion-like p53 Amyloids in Cancer

(2019) Ambuja Navalkar et al.   BIOCHEMISTRY

TDP-43 regulates transcription at protein-coding genes and Alu retrotransposons

(2019) Andrés A. Morera et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Melatonin interacts with repeat domain of Tau to mediate disaggregation of paired helical filaments

(2019) Abhishek Ankur Balmik et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Phase Separation of Zonula Occludens Proteins Drives Formation of Tight Junctions

(2019) Oliver Beutel et al.   CELL

DDX3X: stressing the NLRP3 inflammasome

(2019) Daniel Fox et al.   CELL RESEARCH

Targeting intrinsically disordered proteins involved in cancer

(2019) Patricia Santofimia-Castaño et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanisms of secretion and spreading of pathological tau protein

(2019) Cecilia A. Brunello et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Role of Post-Translational Modifications in the Phase Transitions of Intrinsically Disordered Proteins

(2019) Izzy Owen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Formation of biological condensates via phase separation: Characteristics, analytical methods, and physiological implications

(2019) Zhe Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interplay between ubiquitylation and SUMOylation: Empowered by phase separation

(2019) Jianping Jin   JOURNAL OF BIOLOGICAL CHEMISTRY

The Control Centers of Biomolecular Phase Separation: How Membrane Surfaces, PTMs, and Active Processes Regulate Condensation

(2019) Wilton T. Snead et al.   MOLECULAR CELL

Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS Mutations

(2019) Amirhossein Ghanbari Niaki et al.   MOLECULAR CELL

Binding and dynamics of melatonin at the interface of phosphatidylcholine-cholesterol membranes

(2019) Huixia Lu et al.   PLoS One

Physiological, Pathological, and Targetable Membraneless Organelles in Neurons

(2019) Veronica H. Ryan et al.   TRENDS IN NEUROSCIENCES

Alterations in lipid metabolism of spinal cord linked to amyotrophic lateral sclerosis

(2019) Adriano Britto Chaves-Filho et al.   Scientific Reports

VDAC1 is essential for neurite maintenance and the inhibition of its oligomerization protects spinal cord from demyelination and facilitates locomotor function recovery after spinal cord injury

(2019) Vera Paschon et al.   Scientific Reports

Enhanced Tau Protein Translation by Hyper-Excitation

(2019) Shunsuke Kobayashi et al.   Frontiers in Aging Neuroscience

YTHDF2 Binds to 5-Methylcytosine in RNA and Modulates the Maturation of Ribosomal RNA

(2019) Xiaoxia Dai et al.   ANALYTICAL CHEMISTRY

Site-Specific Hyperphosphorylation Inhibits, Rather than Promotes, Tau Fibrillization, Seeding Capacity, and Its Microtubule Binding

(2019) Mahmood Haj-Yahya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Melatonin inhibits inflammasome-associated activation of endothelium and macrophages attenuating pulmonary arterial hypertension

(2019) Jingyuan Zhang et al.   CARDIOVASCULAR RESEARCH

Regulation of apoptosis by E3 ubiquitin ligases in ubiquitin proteasome system

(2019) Akshay Sharma et al.   CELL BIOLOGY INTERNATIONAL

m 6 A facilitates YTHDF‐independent phase separation

(2019) Si‐Yu Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lipid rafts in glial cells: Role in neuroinflammation and pain processing

(2019) Yury I. Miller et al.   JOURNAL OF LIPID RESEARCH

The ins and outs of lipid rafts: Functions in intracellular cholesterol homeostasis, microparticles, and cell membranes

(2019) Amber B Ouweneel et al.   JOURNAL OF LIPID RESEARCH

ATP Controls the Aggregation of Aβ16–22 Peptides

(2019) Saikat Pal et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Functions of N6-methyladenosine and its role in cancer

(2019) Liuer He et al.   Molecular Cancer

The m6A epitranscriptome: transcriptome plasticity in brain development and function

(2019) Ido Livneh et al.   NATURE REVIEWS NEUROSCIENCE

Exploring the proteome associated with the mRNA encoding the D1 reaction center protein of Photosystem II in plant chloroplasts

(2019) Kenneth P. Watkins et al.   PLANT JOURNAL

Mechanisms for Active Regulation of Biomolecular Condensates

(2019) Johannes Söding et al.   TRENDS IN CELL BIOLOGY

N6-Methyladenosine: A Potential Breakthrough for Human Cancer

(2019) Lina Liu et al.   Molecular Therapy-Nucleic Acids

New potential biomarker for stratification of patients for pharmacological vitamin C in adjuvant settings of cancer therapy

(2019) Rumiana Bakalova et al.   Redox Biology

Melatonin and Melatonergic Influence on Neuronal Transcription Factors: Implications for the Development of Novel Therapies for Neurodegenerative Disorders

(2019) O.J. Onaolapo et al.   Current Neuropharmacology

Acute tau knockdown in the hippocampus of adult mice causes learning and memory deficits

(2018) Ramon Velazquez et al.   AGING CELL

P-Bodies: Composition, Properties, and Functions

(2018) Yang Luo et al.   BIOCHEMISTRY

Role of the cell membrane interface in modulating production and uptake of Alzheimer's beta amyloid protein

(2018) Prashant Bharadwaj et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Non-bilayer structures in mitochondrial membranes regulate ATP synthase activity

(2018) Sardar E. Gasanov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation

(2018) Mario Hofweber et al.   CELL

Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules

(2018) Sebastian Markmiller et al.   CELL

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

(2018) Elahu G. Sustarsic et al.   Cell Metabolism

Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation

(2018) Daxiao Sun et al.   CELL RESEARCH

RNA N6-methyladenosine modification in cancers: current status and perspectives

(2018) Xiaolan Deng et al.   CELL RESEARCH

Relationships Between Tau and Glucose Metabolism Reflect Alzheimer’s Disease Pathology in Cognitively Normal Older Adults

(2018) Jenna N Adams et al.   CEREBRAL CORTEX

Electrostatic Interactions in Protein Structure, Folding, Binding, and Condensation

(2018) Huan-Xiang Zhou et al.   CHEMICAL REVIEWS

How cardiolipin peroxidation alters the properties of the inner mitochondrial membrane?

(2018) Marjut Vähäheikkilä et al.   CHEMISTRY AND PHYSICS OF LIPIDS

The Dynamic Nature of the Nuclear Envelope

(2018) Paola De Magistris et al.   CURRENT BIOLOGY

Tau protein liquid–liquid phase separation can initiate tau aggregation

(2018) Susanne Wegmann et al.   EMBO JOURNAL

Tau ablation in mice leads to pancreatic β cell dysfunction and glucose intolerance

(2018) Nadeeja Wijesekara et al.   FASEB JOURNAL

Cutting Edge: Mitochondrial Assembly of the NLRP3 Inflammasome Complex Is Initiated at Priming

(2018) Eric I. Elliott et al.   JOURNAL OF IMMUNOLOGY

The Role of RNA in Biological Phase Separations

(2018) Marta M. Fay et al.   JOURNAL OF MOLECULAR BIOLOGY

Advances in Understanding Stimulus-Responsive Phase Behavior of Intrinsically Disordered Protein Polymers

(2018) Kiersten M. Ruff et al.   JOURNAL OF MOLECULAR BIOLOGY

Melatonin increases brown adipose tissue mass and function in Zücker diabetic fatty rats: implications for obesity control

(2018) Gumersindo Fernández Vázquez et al.   JOURNAL OF PINEAL RESEARCH

Melatonin and its metabolites vs oxidative stress: From individual actions to collective protection

(2018) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Melatonin ameliorates Aβ42 -induced alteration of βAPP-processing secretases via the melatonin receptor through the Pin1/GSK3β/NF-κB pathway in SH-SY5Y cells

(2018) Vorapin Chinchalongporn et al.   JOURNAL OF PINEAL RESEARCH

Perhydroxyl Radical (HO2•) as Inducer of the Isoprostane Lipid Peroxidation in Mitochondria

(2018) A. Panov   MOLECULAR BIOLOGY

Ubiquitin Modulates Liquid-Liquid Phase Separation of UBQLN2 via Disruption of Multivalent Interactions

(2018) Thuy P. Dao et al.   MOLECULAR CELL

A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation

(2018) Eran Kotler et al.   MOLECULAR CELL

High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies

(2018) Ji-Young Youn et al.   MOLECULAR CELL

N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications

(2018) Yang Wang et al.   NATURE NEUROSCIENCE

SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function

(2018) Yuzhang Du et al.   NUCLEIC ACIDS RESEARCH

Melatonin induces the apoptosis and inhibits the proliferation of human gastric cancer cells via blockade of the AKT/MDM2 pathway

(2018) Jun Song et al.   ONCOLOGY REPORTS

Protective roles of melatonin against the amyloid-dependent development of Alzheimer’s disease: A critical review

(2018) Bruno Vincent   PHARMACOLOGICAL RESEARCH

Chloroplast Translation: Structural and Functional Organization, Operational Control, and Regulation

(2018) Reimo Zoschke et al.   PLANT CELL

Depletion of mRNA export regulator DBP5/DDX19, GLE1 or IPPK that is a key enzyme for the production of IP6, resulting in differentially altered cytoplasmic mRNA expression and specific cell defect

(2018) Masumi Okamura et al.   PLoS One

RNA-mediated gene regulation is less evolvable than transcriptional regulation

(2018) Joshua L. Payne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome

(2018) Briana Van Treeck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The interactions of p53 with tau and Aß as potential therapeutic targets for Alzheimer’s disease

(2018) Maja Jazvinšćak Jembrek et al.   PROGRESS IN NEUROBIOLOGY

RNA buffers the phase separation behavior of prion-like RNA binding proteins

(2018) Shovamayee Maharana et al.   SCIENCE

A liquid phase of synapsin and lipid vesicles

(2018) Dragomir Milovanovic et al.   SCIENCE

Translational Control by Prion-like Proteins

(2018) Liying Li et al.   TRENDS IN CELL BIOLOGY

Protein Phase Separation: A New Phase in Cell Biology

(2018) Steven Boeynaems et al.   TRENDS IN CELL BIOLOGY

Reading m 6 A in the Transcriptome: m 6 A-Binding Proteins

(2018) Deepak P. Patil et al.   TRENDS IN CELL BIOLOGY

N6-methyladenosine links RNA metabolism to cancer progression

(2018) Dongjun Dai et al.   Cell Death & Disease

Mitochondria-associated ER membranes (MAMs) and lysosomal storage diseases

(2018) Ida Annunziata et al.   Cell Death & Disease

α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease

(2018) Marthe H. R. Ludtmann et al.   Nature Communications

Structural and functional analysis of mRNA export regulation by the nuclear pore complex

(2018) Daniel H. Lin et al.   Nature Communications

Loss of mRNA surveillance pathways results in widespread protein aggregation

(2018) Nur Hidayah Jamar et al.   Scientific Reports

TDP-43 regulation of stress granule dynamics in neurodegenerative disease-relevant cell types

(2018) Yousra Khalfallah et al.   Scientific Reports

Anti-β-sheet conformation monoclonal antibody reduces tau and Aβ oligomer pathology in an Alzheimer’s disease model

(2018) Fernando Goñi et al.   Alzheimers Research & Therapy

METTL3-mediated m6A modification is required for cerebellar development

(2018) Chen-Xin Wang et al.   PLOS BIOLOGY

Context-dependent deposition and regulation of mRNAs in P-bodies

(2018) Congwei Wang et al.   eLife

Pi-Pi contacts are an overlooked protein feature relevant to phase separation

(2018) Robert McCoy Vernon et al.   eLife

Dual roles for ATP in the regulation of phase separated protein aggregates in Xenopus oocyte nucleoli

(2018) Michael H Hayes et al.   eLife

Melatonin Mitigates Kainic Acid-Induced Neuronal Tau Hyperphosphorylation and Memory Deficits through Alleviating ER Stress

(2018) Cai Shi et al.   Frontiers in Molecular Neuroscience

The Close Encounter Between Alpha-Synuclein and Mitochondria

(2018) Mattia Vicario et al.   Frontiers in Neuroscience

Cytochrome b 5 reductase is the component from neuronal synaptic plasma membrane vesicles that generates superoxide anion upon stimulation by cytochrome c

(2018) Alejandro K. Samhan-Arias et al.   Redox Biology

YTH Domain: A Family of N 6 -methyladenosine (m 6 A) Readers

(2018) Shanhui Liao et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Translation Control by p53

(2018) Justina Kasteri et al.   Cancers

ATP enhances at low concentrations but dissolves at high concentrations liquid-liquid phase separation (LLPS) of ALS/FTD-causing FUS

(2018) Jian Kang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Aberrant cardiolipin metabolism is associated with cognitive deficiency and hippocampal alteration in tafazzin knockdown mice

(2018) Laura K. Cole et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mutant TP53 G245C and R273H promote cellular malignancy in esophageal squamous cell carcinoma

(2018) Nan Kang et al.   BMC CELL BIOLOGY

Amyloid-β Aggregation on Model Lipid Membranes: An Atomic Force Microscopy Study

(2018) Francis Hane et al.   JOURNAL OF ALZHEIMERS DISEASE

GSK3 and Tau: Two Convergence Points in Alzheimer's Disease

(2018) Felix Hernandez et al.   JOURNAL OF ALZHEIMERS DISEASE

Cardiolipin Profile Changes are Associated to the Early Synaptic Mitochondrial Dysfunction in Alzheimer's Disease

(2018) Vera F. Monteiro-Cardoso et al.   JOURNAL OF ALZHEIMERS DISEASE

The molecular language of membraneless organelles

(2018) Edward Gomes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Who's In and Who's Out—Compositional Control of Biomolecular Condensates

(2018) Jonathon A. Ditlev et al.   JOURNAL OF MOLECULAR BIOLOGY

Multiple Modes of Protein–Protein Interactions Promote RNP Granule Assembly

(2018) Tanja Mittag et al.   JOURNAL OF MOLECULAR BIOLOGY

SUMO-Mediated Regulation of Nuclear Functions and Signaling Processes

(2018) Xiaolan Zhao   MOLECULAR CELL

Melatonin protects hippocampal HT22 cells from the effects of serum deprivation specifically targeting mitochondria

(2018) Erica Cesarini et al.   PLoS One

Stress Granules and Processing Bodies in Translational Control

(2018) Pavel Ivanov et al.   Cold Spring Harbor Perspectives in Biology

Compartmentalised RNA catalysis in membrane-free coacervate protocells

(2018) Björn Drobot et al.   Nature Communications

The involvement of tau in nucleolar transcription and the stress response

(2018) Mahmoud B. Maina et al.   Acta Neuropathologica Communications

Role of the Pyruvate Dehydrogenase Complex in Metabolic Remodeling: Differential Pyruvate Dehydrogenase Complex Functions in Metabolism

(2018) Sungmi Park et al.   Diabetes & Metabolism Journal

The role of RNA adenosine demethylases in the control of gene expression

(2018) Veronika Rajecka et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

It's complicated… m6A-dependent regulation of gene expression in cancer

(2018) Christina M. Fitzsimmons et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Interplay between Membrane Curvature and Cholesterol: Role of Palmitoylated Caveolin-1

(2018) Anjali Krishna et al.   BIOPHYSICAL JOURNAL

Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

(2018) Ann Boija et al.   CELL

Relation Between Stress Granules and Cytoplasmic Protein Aggregates Linked to Neurodegenerative Diseases

(2018) Ioana Dobra et al.   Current Neurology and Neuroscience Reports

Friend or foe — post-translational modifications as regulators of phase separation and RNP granule dynamics

(2018) Mario Hofweber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome

(2018) Yuanchen Dong et al.   NATURE

m6A modification controls the innate immune response to infection by targeting type I interferons

(2018) Roni Winkler et al.   NATURE IMMUNOLOGY

Long-range regulation of p53 DNA binding by its intrinsically disordered N-terminal transactivation domain

(2018) Alexander S. Krois et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay

(2018) Marisa Kamelgarn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyperphosphorylation of Tau Associates With Changes in Its Function Beyond Microtubule Stability

(2018) Alejandra D. Alonso et al.   Frontiers in Cellular Neuroscience

Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation

(2018) Xiang Zhong et al.   Cell Reports

Real-Time Imaging of Mitochondrial ATP Dynamics Reveals the Metabolic Setting of Single Cells

(2018) Maria R. Depaoli et al.   Cell Reports

Neurodegeneration-associated FUS is a novel regulator of circadian gene expression

(2018) Xin Jiang et al.   Translational Neurodegeneration

Lowering line tension with high cholesterol content induces a transition from macroscopic to nanoscopic phase domains in model biomembranes

(2018) Wen-Chyan Tsai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

An N-methyladenosine at the transited codon 273 of p53 pre-mRNA promotes the expression of R273H mutant protein and drug resistance of cancer cells

(2018) Mohammad B. Uddin et al.   BIOCHEMICAL PHARMACOLOGY

The role of nonbilayer phospholipids in mitochondrial structure and function

(2017) Writoban Basu Ball et al.   FEBS LETTERS

RNA-binding proteins in neurodegeneration: mechanisms in aggregate

(2017) Erin G. Conlon et al.   GENES & DEVELOPMENT

Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis

(2017) Liping Li et al.   HUMAN MOLECULAR GENETICS

The crucial role of protein phosphorylation in cell signaling and its use as targeted therapy (Review)

(2017) Fatima Ardito et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Distinct modulatory role of RNA in the aggregation of the tumor suppressor protein p53 core domain

(2017) Petar Stefanov Kovachev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements

(2017) Shona A. Mookerjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs

(2017) Yuan Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions

(2017) Hoi-Shan Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tau deletion promotes brain insulin resistance

(2017) Elodie Marciniak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic alterations of m6A regulators predict poorer survival in acute myeloid leukemia

(2017) Chau-To Kwok et al.   Journal of Hematology & Oncology

Osmotic Shock Induced Protein Destabilization in Living Cells and Its Reversal by Glycine Betaine

(2017) Samantha S. Stadmiller et al.   JOURNAL OF MOLECULAR BIOLOGY

Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation

(2017) Frederik De Smet et al.   JOURNAL OF PATHOLOGY

Stress Propagation through Biological Lipid Bilayers in Silico

(2017) Camilo Aponte-Santamaría et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

“Gamete On” for m 6 A: YTHDF2 Exerts Essential Functions in Female Fertility

(2017) Boxuan Simen Zhao et al.   MOLECULAR CELL

Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control

(2017) Isaia Barbieri et al.   NATURE

The mystery of membrane organization: composition, regulation and roles of lipid rafts

(2017) Erdinc Sezgin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Oxidative Stress: Harms and Benefits for Human Health

(2017) Gabriele Pizzino et al.   Oxidative Medicine and Cellular Longevity

Changes in aggregation states of light-harvesting complexes as a mechanism for modulating energy transfer in desert crust cyanobacteria

(2017) Leeat Bar Eyal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons

(2017) Pallavi P. Gopal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ALKBH5-dependent m6A demethylation controls splicing and stability of long 3′-UTR mRNAs in male germ cells

(2017) Chong Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release

(2017) Yalikun Suofu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptation of mRNA structure to control protein folding

(2017) Guilhem Faure et al.   RNA Biology

ATP as a biological hydrotrope

(2017) Avinash Patel et al.   SCIENCE

Liquid phase condensation in cell physiology and disease

(2017) Yongdae Shin et al.   SCIENCE

Transcription and Splicing Factor TDP-43: Role in Regulation of Gene Expression in Testis

(2017) Prabhakara Reddi   SEMINARS IN REPRODUCTIVE MEDICINE

Melatonin improves survival and respiratory activity of yeast cells challenged by alpha-synuclein and menadione

(2017) Mariana A. Zampol et al.   YEAST

Uncovering the SUMOylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurification

(2017) Frédéric Lamoliatte et al.   Nature Communications

P-body proteins regulate transcriptional rewiring to promote DNA replication stress resistance

(2017) Raphael Loll-Krippleber et al.   Nature Communications

Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau

(2017) Susmitha Ambadipudi et al.   Nature Communications

Glycolytic Enzymes Coalesce in G Bodies under Hypoxic Stress

(2017) Meiyan Jin et al.   Cell Reports

Tau Oligomers: Cytotoxicity, Propagation, and Mitochondrial Damage

(2017) Scott S. Shafiei et al.   Frontiers in Aging Neuroscience

RNA stores tau reversibly in complex coacervates

(2017) Xuemei Zhang et al.   PLOS BIOLOGY

Mitochondria and lipid raft-located FOF1-ATP synthase as major therapeutic targets in the antileishmanial and anticancer activities of ether lipid edelfosine

(2017) Janny A. Villa-Pulgarín et al.   PLoS Neglected Tropical Diseases

Control of lipid domain organization by a biomimetic contractile actomyosin cortex

(2017) Sven Kenjiro Vogel et al.   eLife

Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins

(2017) Tyler S Harmon et al.   eLife

Specific Distribution of Phosphatidylglycerol to Photosystem Complexes in the Thylakoid Membrane

(2017) Koichi Kobayashi et al.   Frontiers in Plant Science

Ddx19 links mRNA nuclear export with progression of transcription and replication and suppresses genomic instability upon DNA damage in proliferating cells

(2017) Dana Hodroj et al.   Nucleus

The DEAD-Box RNA Helicase DDX3 Interacts with m6A RNA Demethylase ALKBH5

(2017) Abdullah Shah et al.   Stem Cells International

Dysregulation of RNA Binding Protein Aggregation in Neurodegenerative Disorders

(2017) Brandon Maziuk et al.   Frontiers in Molecular Neuroscience

Protein Quality Control by Molecular Chaperones in Neurodegeneration

(2017) Aaron Ciechanover et al.   Frontiers in Neuroscience

Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic Target

(2017) Amadou K. S. Camara et al.   Frontiers in Physiology

Ddx19 links mRNA nuclear export with progression of transcription and replication and suppresses genomic instability upon DNA damage in proliferating cells

(2017) Dana Hodroj et al.   Nucleus

Doxycycline induces apoptosis via ER stress selectively to cells with a cancer stem cell-like properties: importance of stem cell plasticity

(2017) Takashi Matsumoto et al.   Oncogenesis

Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice

(2017) Ulkan Kilic et al.   Redox Biology

The landscape of transcription errors in eukaryotic cells

(2017) Jean-Francois Gout et al.   Science Advances

Epitranscriptomics: Toward A Better Understanding of RNA Modifications

(2017) Xushen Xiong et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Evolution of Voltage-Dependent Anion Channel Function: From Molecular Sieve to Governator to Actuator of Ferroptosis

(2017) John J. Lemasters   Frontiers in Oncology

Hyperphosphorylated Tau is a Cause of Neuronal Dysfunction in Tauopathy

(2017) Akihiko Takashima   JOURNAL OF ALZHEIMERS DISEASE

Phosphorylated Tau: Toxic, Protective, or None of the Above

(2017) Rudy J. Castellani et al.   JOURNAL OF ALZHEIMERS DISEASE

Tau Overexpression Inhibits Cell Apoptosis with the Mechanisms Involving Multiple Viability-Related Factors

(2017) Hai-Hong Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

Chloroplastic biosynthesis of melatonin and its involvement in protection of plants from salt stress

(2017) Xiaodong Zheng et al.   Scientific Reports

Effect of head group and lipid tail oxidation in the cell membrane revealed through integrated simulations and experiments

(2017) M. Yusupov et al.   Scientific Reports

The influence of curvature on the properties of the plasma membrane. Insights from atomistic molecular dynamics simulations

(2017) Semen O. Yesylevskyy et al.   Scientific Reports

Ubiquitin-dependent and independent roles of SUMO in proteostasis

(2016) Frauke Liebelt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Distribution and dynamics of electron transport complexes in cyanobacterial thylakoid membranes

(2016) Lu-Ning Liu   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The ionization properties of cardiolipin and its variants in model bilayers

(2016) Murugappan Sathappa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A Physiological Role for Alpha-Synuclein in the Regulation of ATP Synthesis

(2016) Marthe Ludtmann et al.   BIOPHYSICAL JOURNAL

Cardiac Calcium ATPase Dimerization Measured by Cross-Linking and Fluorescence Energy Transfer

(2016) Daniel J. Blackwell et al.   BIOPHYSICAL JOURNAL

Hyperphosphorylated tau in patients with refractory epilepsy correlates with cognitive decline: a study of temporal lobe resections

(2016) Xin You Tai et al.   BRAIN

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

(2016) Saumya Jain et al.   CELL

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

(2016) Marina Feric et al.   CELL

Superoxide Ion: Generation and Chemical Implications

(2016) Maan Hayyan et al.   CHEMICAL REVIEWS

The integrated stress response

(2016) Karolina Pakos‐Zebrucka et al.   EMBO REPORTS

Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling

(2016) Martin D. Brand   FREE RADICAL BIOLOGY AND MEDICINE

Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics

(2016) Dun-Xian Tan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNA in Control of Gene Expression: An Overview of Nuclear Functions

(2016) Caterina Catalanotto et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Modulation of Intrinsically Disordered Protein Function by Post-translational Modifications

(2016) Alaji Bah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane curvature in cell biology: An integration of molecular mechanisms

(2016) Iris K. Jarsch et al.   JOURNAL OF CELL BIOLOGY

Sumoylation of eIF4A2 affects stress granule formation

(2016) Jirapas Jongjitwimol et al.   JOURNAL OF CELL SCIENCE

Oxidized phosphatidylcholine induces the activation of NLRP3 inflammasome in macrophages

(2016) Sang Hyeon Yeon et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Imaging mass spectrometry reveals loss of polyunsaturated cardiolipins in the cortical contusion, hippocampus, and thalamus after traumatic brain injury

(2016) Louis J. Sparvero et al.   JOURNAL OF NEUROCHEMISTRY

Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase

(2016) M. H. R. Ludtmann et al.   JOURNAL OF NEUROSCIENCE

Polyamine/Nucleotide Coacervates Provide Strong Compartmentalization of Mg2+, Nucleotides, and RNA

(2016) Erica A. Frankel et al.   LANGMUIR

Oxidation of Membrane Curvature-Regulating Phosphatidylethanolamine Lipid Results in Formation of Bilayer and Cubic Structures

(2016) Shalene Sankhagowit et al.   LANGMUIR

RNA-Based Coacervates as a Model for Membraneless Organelles: Formation, Properties, and Interfacial Liposome Assembly

(2016) William M. Aumiller et al.   LANGMUIR

Extracellular ATP a New Player in Cancer Metabolism: NSCLC Cells Internalize ATP In Vitro and In Vivo Using Multiple Endocytic Mechanisms

(2016) Y. Qian et al.   MOLECULAR CANCER RESEARCH

Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases

(2016) Ping Wang et al.   MOLECULAR CELL

The F0F1ATP Synthase Complex Localizes to Membrane Rafts in Gonadotrope Cells

(2016) Krystal Allen-Worthington et al.   MOLECULAR ENDOCRINOLOGY

Decoding ALS: from genes to mechanism

(2016) J. Paul Taylor et al.   NATURE

The multiple functions of RNA helicases as drivers and regulators of gene expression

(2016) Cyril F. Bourgeois et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Close Relationships Between the PSII Repair Cycle and Thylakoid Membrane Dynamics

(2016) Miho Yoshioka-Nishimura   PLANT AND CELL PHYSIOLOGY

Ultradonut topology of the nuclear envelope

(2016) Mehdi Torbati et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amplification of RNA by an RNA polymerase ribozyme

(2016) David P. Horning et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phase separation of signaling molecules promotes T cell receptor signal transduction

(2016) Xiaolei Su et al.   SCIENCE

Messenger RNA modifications: Form, distribution, and function

(2016) W. V. Gilbert et al.   SCIENCE

ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain

(2016) Alexander E. Conicella et al.   STRUCTURE

Mitochondrial Cristae: Where Beauty Meets Functionality

(2016) Sara Cogliati et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

Principles and Properties of Stress Granules

(2016) David S.W. Protter et al.   TRENDS IN CELL BIOLOGY

Elevated expression of ZNF217 promotes prostate cancer growth by restraining ferroportin-conducted iron egress

(2016) Xingkang Jiang et al.   Oncotarget

Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation

(2016) Lei-Lei Jiang et al.   Scientific Reports

Increased N 6 -methyladenosine in Human Sperm RNA as a Risk Factor for Asthenozoospermia

(2016) Ying Yang et al.   Scientific Reports

Abnormal tau induces cognitive impairment through two different mechanisms: synaptic dysfunction and neuronal loss

(2016) J. Di et al.   Scientific Reports

Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis

(2016) Michael I. Carr et al.   Cell Reports

ALS-Causing Mutations Significantly Perturb the Self-Assembly and Interaction with Nucleic Acid of the Intrinsically Disordered Prion-Like Domain of TDP-43

(2016) Liangzhong Lim et al.   PLOS BIOLOGY

ATPase activity of the DEAD-box protein Dhh1 controls processing body formation

(2016) Christopher Frederick Mugler et al.   eLife

Distinct stages in stress granule assembly and disassembly

(2016) Joshua R Wheeler et al.   eLife

Beneficial Roles of Melatonin on Redox Regulation of Photosynthetic Electron Transport and Synthesis of D1 Protein in Tomato Seedlings under Salt Stress

(2016) Xiaoting Zhou et al.   Frontiers in Plant Science

Membrane roughness as a sensitive parameter reflecting the status of neuronal cells in response to chemical and nanoparticle treatments

(2016) Chia-Wei Lee et al.   JOURNAL OF NANOBIOTECHNOLOGY

The ER stress sensor PERK luminal domain functions as a molecular chaperone to interact with misfolded proteins

(2016) Peng Wang et al.   Acta Crystallographica Section D-Structural Biology

Interplay between Ubiquitin, SUMO, and Poly(ADP-Ribose) in the Cellular Response to Genotoxic Stress

(2016) Stefania Pellegrino et al.   Frontiers in Genetics

N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5

(2016) Shui Zou et al.   Scientific Reports

Role of mitochondrial raft-like microdomains in the regulation of cell apoptosis

(2015) Tina Garofalo et al.   APOPTOSIS

Nuclear Magnetic Resonance Spectroscopy Characterization of Interaction of Tau with DNA and Its Regulation by Phosphorylation

(2015) Haoling Qi et al.   BIOCHEMISTRY

The organization of melatonin in lipid membranes

(2015) Hannah Dies et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

Coordination of m 6 A mRNA Methylation and Gene Transcription by ZFP217 Regulates Pluripotency and Reprogramming

(2015) Francesca Aguilo et al.   Cell Stem Cell

Amyloidogenicity of p53: A Hidden Link Between Protein Misfolding and Cancer

(2015) Hao Gong et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Nuclear Pore Basket Proteins Are Tethered to the Nuclear Envelope and Can Regulate Membrane Curvature

(2015) Noémi Mészáros et al.   DEVELOPMENTAL CELL

ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons

(2015) J. Lenzi et al.   Disease Models & Mechanisms

Nanodomains in biological membranes

(2015) Yuanqing Ma et al.   Essays in Biochemistry

Biological membranes

(2015) H. Watson   Essays in Biochemistry

Melatonin affects voltage-dependent calcium and potassium currents in MCF-7 cell line cultured either in growth or differentiation medium

(2015) Roberta Squecco et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The conformational plasticity of eukaryotic RNA-dependent ATPases

(2015) Sevim Ozgur et al.   FEBS Journal

LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease

(2015) Y. Y. Tyurina et al.   FREE RADICAL RESEARCH

High membrane permeability for melatonin

(2015) Haijie Yu et al.   JOURNAL OF GENERAL PHYSIOLOGY

Cardiolipin and Its Different Properties in Mitophagy and Apoptosis

(2015) Xiao-Xiao Li et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3β pathway in the mouse hippocampus

(2015) Tahir Ali et al.   JOURNAL OF PINEAL RESEARCH

Melatonin: an ancient molecule that makes oxygen metabolically tolerable

(2015) Lucien C. Manchester et al.   JOURNAL OF PINEAL RESEARCH

The p53 C Terminus Controls Site-Specific DNA Binding and Promotes Structural Changes within the Central DNA Binding Domain

(2015) Oleg Laptenko et al.   MOLECULAR CELL

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II

(2015) Kathleen A. Burke et al.   MOLECULAR CELL

Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

(2015) Timothy J. Nott et al.   MOLECULAR CELL

N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions

(2015) Nian Liu et al.   NATURE

Phosphorylation-mediated RNA/peptide complex coacervation as a model for intracellular liquid organelles

(2015) William M. Aumiller et al.   Nature Chemistry

Polymer physics of intracellular phase transitions

(2015) Clifford P. Brangwynne et al.   Nature Physics

p53 in survival, death and metabolic health: a lifeguard with a licence to kill

(2015) Flore Kruiswijk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tau in physiology and pathology

(2015) Yipeng Wang et al.   NATURE REVIEWS NEUROSCIENCE

ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

(2015) Tetsuro Murakami et al.   NEURON

Tau stabilizes microtubules by binding at the interface between tubulin heterodimers

(2015) Harindranath Kadavath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uncoupling protein 1 binds one nucleotide per monomer and is stabilized by tightly bound cardiolipin

(2015) Yang Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics

(2015) Shana Elbaum-Garfinkle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low levels of lipid oxidation radically increase the passive permeability of lipid bilayers

(2015) Kristina A. Runas et al.   Soft Matter

Structural Impact of Tau Phosphorylation at Threonine 231

(2015) Martin Schwalbe et al.   STRUCTURE

The Mechanism of ATP-Dependent Allosteric Protection of Akt Kinase Phosphorylation

(2015) Shaoyong Lu et al.   STRUCTURE

Recent Insights into the Structure, Regulation, and Function of the V-ATPases

(2015) Kristina Cotter et al.   TRENDS IN BIOCHEMICAL SCIENCES

Alterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?

(2015) Anaïs Aulas et al.   Frontiers in Cellular Neuroscience

Sumo and the cellular stress response

(2015) Jorrit M. Enserink   Cell Division

IRSp53 senses negative membrane curvature and phase separates along membrane tubules

(2015) Coline Prévost et al.   Nature Communications

p53 attenuates AKT signaling by modulating membrane phospholipid composition

(2015) Natalia Rueda-Rincon et al.   Oncotarget

Hexavalent chromium induces apoptosis in male somatic and spermatogonial stem cells via redox imbalance

(2015) Joydeep Das et al.   Scientific Reports

The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly

(2015) Carmela Sidrauski et al.   eLife

Fate by RNA methylation: m6A steers stem cell pluripotency

(2015) Boxuan Zhao et al.   GENOME BIOLOGY

SUMOylation: Novel Neuroprotective Approach for Alzheimer’s Disease?

(2015) Juliana B Hoppe et al.   Aging and Disease

Lipid peroxidation modifies the assembly of biological membranes “The Lipid Whisker Model”

(2015) Ángel Catalá   Frontiers in Physiology

Cortical tau load is associated with white matter hyperintensities

(2015) Kirsty E. McAleese et al.   Acta Neuropathologica Communications

Externalization of Cardiolipin as an “Eat-Me” Mitophageal Signal is Facilitated by NDPK-D

(2015) Zhentai Huang et al.   BIOPHYSICAL JOURNAL

Apoptosis-Associated Speck-like Protein Containing a CARD Forms Specks but Does Not Activate Caspase-1 in the Absence of NLRP3 during Macrophage Swelling

(2015) Vincent Compan et al.   JOURNAL OF IMMUNOLOGY

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

Membrane-Bound CYB5R3 Is a Common Effector of Nutritional and Oxidative Stress Response Through FOXO3a and Nrf2

(2014) Emilio Siendones et al.   ANTIOXIDANTS & REDOX SIGNALING

Functions of FUS/TLS From DNA Repair to Stress Response: Implications for ALS

(2014) Reddy Ranjith Kumar Sama et al.   ASN Neuro

Protein-Induced Membrane Curvature Alters Local Membrane Tension

(2014) Padmini Rangamani et al.   BIOPHYSICAL JOURNAL

Pathological stress granules in Alzheimer’s disease

(2014) Peter E.A. Ash et al.   BRAIN RESEARCH

Mutant p53 in Cancer: New Functions and Therapeutic Opportunities

(2014) Patricia A.J. Muller et al.   CANCER CELL

Synonymous Mutations Frequently Act as Driver Mutations in Human Cancers

(2014) Fran Supek et al.   CELL

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

Models and mechanisms of Hofmeister effects in electrolyte solutions, and colloid and protein systems revisited

(2014) Andrea Salis et al.   CHEMICAL SOCIETY REVIEWS

Purified NADH-cytochrome b5 reductase is a novel superoxide anion source inhibited by apocynin: sensitivity to nitric oxide and peroxynitrite

(2014) Alejandro K. Samhan-Arias et al.   FREE RADICAL BIOLOGY AND MEDICINE

External mitochondrial NADH-dependent reductase of redox cyclers: VDAC1 or Cyb5R3?

(2014) Anna B. Nikiforova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Limiting the power of p53 through the ubiquitin proteasome pathway

(2014) Vinod Pant et al.   GENES & DEVELOPMENT

Wrestling with stress: Roles of protein SUMOylation and deSUMOylation in cell stress response

(2014) Chun Guo et al.   IUBMB LIFE

Tau Pathology Induces Intraneuronal Cholesterol Accumulation

(2014) Frauke Glöckner et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Melatonin, energy metabolism, and obesity: a review

(2014) J. Cipolla-Neto et al.   JOURNAL OF PINEAL RESEARCH

Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physicochemical analysis

(2014) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Melatonin down-regulates MDM2 gene expression and enhances p53 acetylation in MCF-7 cells

(2014) Sara Proietti et al.   JOURNAL OF PINEAL RESEARCH

ATP/ADP ratio, the missed connection between mitochondria and the Warburg effect

(2014) Eduardo N. Maldonado et al.   MITOCHONDRION

A Cellular System that Degrades Misfolded Proteins and Protects against Neurodegeneration

(2014) Lili Guo et al.   MOLECULAR CELL

Motor and cognitive deficits in aged tau knockout mice in two background strains

(2014) Peng Lei et al.   Molecular Neurodegeneration

N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells

(2014) Yang Wang et al.   NATURE CELL BIOLOGY

Aβ promotes VDAC1 channel dephosphorylation in neuronal lipid rafts. Relevance to the mechanisms of neurotoxicity in Alzheimer’s disease

(2014) C. Fernandez-Echevarria et al.   NEUROSCIENCE

Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters

(2014) Jayne Loughery et al.   NUCLEIC ACIDS RESEARCH

Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

(2014) Antonio Ayala et al.   Oxidative Medicine and Cellular Longevity

The Interaction between Amyloid-β Peptides and Anionic Lipid Membranes Containing Cholesterol and Melatonin

(2014) Hannah Dies et al.   PLoS One

The aggregation of mutant p53 produces prion-like properties in cancer

(2014) Luciana P Rangel et al.   Prion

Self-assembled FUS binds active chromatin and regulates gene transcription

(2014) Liuqing Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination

(2014) Hong-Bin Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Feeling the hidden mechanical forces in lipid bilayer is an original sense

(2014) A. Anishkin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prion-like aggregation of mutant p53 in cancer

(2014) Jerson L. Silva et al.   TRENDS IN BIOCHEMICAL SCIENCES

Proteostasis impairment in protein-misfolding and -aggregation diseases

(2014) Mark S. Hipp et al.   TRENDS IN CELL BIOLOGY

Regulation of transcription factor activity by interconnected post-translational modifications

(2014) Theresa M. Filtz et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Oxidative stress, cardiolipin and mitochondrial dysfunction in nonalcoholic fatty liver disease

(2014) Giuseppe Paradies   WORLD JOURNAL OF GASTROENTEROLOGY

Inflammasomes

(2014) M. R. de Zoete et al.   Cold Spring Harbor Perspectives in Biology

Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance

(2014) Chi Kwan Tsang et al.   Nature Communications

Cholesterol level affects surface charge of lipid membranes in saline solution

(2014) Aniket Magarkar et al.   Scientific Reports

Localization of mRNAs to the endoplasmic reticulum

(2014) Xianying A. Cui et al.   Wiley Interdisciplinary Reviews-RNA

Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans

(2014) Jennifer T Wang et al.   eLife

Phase transitions of multivalent proteins can promote clustering of membrane receptors

(2014) Sudeep Banjade et al.   eLife

Translation and silencing in RNA granules: a tale of sand grains

(2014) Jerónimo Pimentel et al.   Frontiers in Molecular Neuroscience

P44, the ‘longevity-assurance’ isoform of P53, regulates tau phosphorylation and is activated in an age-dependent fashion

(2013) Mariana Pehar et al.   AGING CELL

Molecular Architecture and Assembly of the Eukaryotic Proteasome

(2013) Robert J. Tomko et al.   Annual Review of Biochemistry

p53 regulates glucose metabolism by miR-34a

(2013) Hwa-Ryeon Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DEAD-Box Helicases Form Nucleotide-Dependent, Long-Lived Complexes with RNA

(2013) Fei Liu et al.   BIOCHEMISTRY

Functional role of cardiolipin in mitochondrial bioenergetics

(2013) Giuseppe Paradies et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Reactive oxygen species at phospholipid bilayers: Distribution, mobility and permeation

(2013) Rodrigo M. Cordeiro   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Packing them up and dusting them off: RNA helicases and mRNA storage

(2013) Christopher Hooper et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Take the (RN)A-train: Localization of mRNA to the endoplasmic reticulum

(2013) Orit Hermesh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

SUMO-targeted ubiquitin ligases

(2013) Annie M. Sriramachandran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The role of ubiquitin modification in the regulation of p53

(2013) Andreas K. Hock et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Intrinsically disordered regions of p53 family are highly diversified in evolution

(2013) Bin Xue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation

(2013) Raffaela Santoro et al.   CARCINOGENESIS

Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function

(2013) J. Ross Buchan et al.   CELL

Higher-Order Assemblies in a New Paradigm of Signal Transduction

(2013) Hao Wu   CELL

Over-Expression of Small Ubiquitin-Related Modifier-1 and Sumoylated p53 in Colon Cancer

(2013) Hongjie Zhang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Regulation of pyruvate metabolism and human disease

(2013) Lawrence R. Gray et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The eIF2α kinases: their structures and functions

(2013) Neysan Donnelly et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Gene regulation by non-coding RNAs

(2013) Veena S. Patil et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

SUMO: A Multifaceted Modifier of Chromatin Structure and Function

(2013) Caelin Cubeñas-Potts et al.   DEVELOPMENTAL CELL

Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation

(2013) Shankar S. Iyer et al.   IMMUNITY

Detergent resistant membrane fractions are involved in calcium signaling in Müller glial cells of retina

(2013) Gopinath Krishnan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Protein SUMOylation, an emerging pathway in amyotrophic lateral sclerosis

(2013) Audrey Dangoumau et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

The ATP Costs and Time Required to Degrade Ubiquitinated Proteins by the 26 S Proteasome

(2013) Andreas Peth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress

(2013) Reddy Ranjith K. Sama et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Molecular Mechanisms of Disease-Causing Missense Mutations

(2013) Shannon Stefl et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular targets underlying SUMO-mediated neuroprotection in brain ischemia

(2013) Vasco Silveirinha et al.   JOURNAL OF NEUROCHEMISTRY

Molecular cloning and functional analysis of serotoninN-acetyltransferase from the cyanobacteriumSynechocystissp. PCC 6803

(2013) Yeong Byeon et al.   JOURNAL OF PINEAL RESEARCH

Evidence for Cardiolipin Binding Sites on the Membrane-Exposed Surface of the Cytochrome bc1

(2013) Clement Arnarez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tau binds ATP and induces its aggregation

(2013) Mina Farid et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Regulation of DNA Damage Responses by Ubiquitin and SUMO

(2013) Stephen P. Jackson et al.   MOLECULAR CELL

Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics

(2013) Desiree M Baron et al.   Molecular Neurodegeneration

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sumoylation of Critical Proteins in Amyotrophic Lateral Sclerosis: Emerging Pathways of Pathogenesis

(2013) Emily Foran et al.   NEUROMOLECULAR MEDICINE

SUMO and Parkinson’s Disease

(2013) Katrin Eckermann   NEUROMOLECULAR MEDICINE

Receptor Trafficking and the Regulation of Synaptic Plasticity by SUMO

(2013) Jia Luo et al.   NEUROMOLECULAR MEDICINE

SUMO and Alzheimer’s Disease

(2013) Linda Lee et al.   NEUROMOLECULAR MEDICINE

Adenine Nucleotide Translocase, Mitochondrial Stress, and Degenerative Cell Death

(2013) Yaxin Liu et al.   Oxidative Medicine and Cellular Longevity

The Observation of Highly Ordered Domains in Membranes with Cholesterol

(2013) Clare L. Armstrong et al.   PLoS One

Interactions between Aβ and Mutated Tau Lead to Polymorphism and Induce Aggregation of Aβ-Mutated Tau Oligomeric Complexes

(2013) Yoav Raz et al.   PLoS One

Human F1F0 ATP Synthase, Mitochondrial Ultrastructure and OXPHOS Impairment: A (Super-)Complex Matter?

(2013) Johann Habersetzer et al.   PLoS One

Stiffened lipid platforms at molecular force foci

(2013) A. Anishkin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cofactor-dependent specificity of a DEAD-box protein

(2013) C. L. Young et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monolayer curvature stabilizes nanoscale raft domains in mixed lipid bilayers

(2013) S. Meinhardt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues

(2013) R. K. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipids of mitochondria

(2013) Susanne E. Horvath et al.   PROGRESS IN LIPID RESEARCH

Melatonin directly interacts with cholesterol and alleviates cholesterol effects in dipalmitoylphosphatidylcholine monolayers

(2013) Youngjik Choi et al.   Soft Matter

Blessings in disguise: biological benefits of prion-like mechanisms

(2013) Gregory A. Newby et al.   TRENDS IN CELL BIOLOGY

Tumour-associated mutant p53 drives the Warburg effect

(2013) Cen Zhang et al.   Nature Communications

Cyclic 3-hydroxymelatonin, a key metabolite enhancing the peroxyl radical scavenging activity of melatonin

(2013) Annia Galano et al.   RSC Advances

 -Synuclein in Parkinson's Disease

(2013) L. Stefanis   Cold Spring Harbor Perspectives in Medicine

Ubiquitin and Proteasomes in Transcription

(2012) Fuqiang Geng et al.   Annual Review of Biochemistry

ATP Utilization and RNA Conformational Rearrangement by DEAD-Box Proteins

(2012) Arnon Henn et al.   Annual Review of Biophysics

Interaction of Tau Protein with Model Lipid Membranes Induces Tau Structural Compaction and Membrane Disruption

(2012) Emmalee M. Jones et al.   BIOCHEMISTRY

Effect of oxidative stress on plasma membrane fluidity of THP-1 induced macrophages

(2012) Carlos de la Haba et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Where the endoplasmic reticulum and the mitochondrion tie the knot: The mitochondria-associated membrane (MAM)

(2012) Arun Raturi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Nanoscale Electrostatic Domains in Cholesterol-Laden Lipid Membranes Create a Target for Amyloid Binding

(2012) Elizabeth Drolle et al.   BIOPHYSICAL JOURNAL

Oxidized Phosphatidylcholines Promote Phase Separation of Cholesterol-Sphingomyelin Domains

(2012) Roman Volinsky et al.   BIOPHYSICAL JOURNAL

Binding of β-Amyloid (1–42) Peptide to Negatively Charged Phospholipid Membranes in the Liquid-Ordered State: Modeling and Experimental Studies

(2012) Hasna Ahyayauch et al.   BIOPHYSICAL JOURNAL

β-Amyloid (1–40) Peptide Interactions with Supported Phospholipid Membranes: A Single-Molecule Study

(2012) Hao Ding et al.   BIOPHYSICAL JOURNAL

The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease

(2012) Oliver D. King et al.   BRAIN RESEARCH

The rebel angel: mutant p53 as the driving oncogene in breast cancer

(2012) D. Walerych et al.   CARCINOGENESIS

Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein

(2012) Weijiao Huang et al.   CELL RESEARCH

Pyruvate Dehydrogenase Kinases in the Nervous System: Their Principal Functions in Neuronal-glial Metabolic Interaction and Neuro-metabolic Disorders

(2012) Mithilesh Kumar Jha et al.   Current Neuropharmacology

Dimerization and direct membrane interaction of Nup53 contribute to nuclear pore complex assembly

(2012) Benjamin Vollmer et al.   EMBO JOURNAL

Cubic phases in membrane lipids

(2012) Boris Tenchov et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth

(2012) Claudia Fallini et al.   HUMAN MOLECULAR GENETICS

A manually curated network of the PML nuclear body interactome reveals an important role for PML-NBs in SUMOylation dynamics

(2012) Ellen Van Damme et al.   International Journal of Biological Sciences

Mutant p53 Aggregates into Prion-like Amyloid Oligomers and Fibrils

(2012) Ana P. D. Ano Bom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Oxidative Phosphorylation, Not Glycolysis, Powers Presynaptic and Postsynaptic Mechanisms Underlying Brain Information Processing

(2012) C. N. Hall et al.   JOURNAL OF NEUROSCIENCE

Contrasting Pathology of the Stress Granule Proteins TIA-1 and G3BP in Tauopathies

(2012) T. Vanderweyde et al.   JOURNAL OF NEUROSCIENCE

Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes

(2012) Dun-Xian Tan et al.   JOURNAL OF PINEAL RESEARCH

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

Regulated protein aggregation: stress granules and neurodegeneration

(2012) Benjamin Wolozin   Molecular Neurodegeneration

Phase transitions in the assembly of multivalent signalling proteins

(2012) Pilong Li et al.   NATURE

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

Functional analysis and consequences of Mdm2 E3 ligase inhibition in human tumor cells

(2012) M Wade et al.   ONCOGENE

Conformational Altered p53 as an Early Marker of Oxidative Stress in Alzheimer's Disease

(2012) Laura Buizza et al.   PLoS One

Structure and Dynamics of Amyloid-β Segmental Polymorphisms

(2012) Workalemahu M. Berhanu et al.   PLoS One

Mimicking the electron transfer chain in photosystem II with a molecular triad thermodynamically capable of water oxidation

(2012) J. D. Megiatto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the yeast F1Fo-ATP synthase dimer and its role in shaping the mitochondrial cristae

(2012) K. M. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress

(2012) S. Bursac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An unusual phosphatidylethanolamine-utilizing cardiolipin synthase is discovered in bacteria

(2012) G. M. Carman   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA helicases

(2012) George W. Owttrim   RNA Biology

The DEAD-box helicase eIF4A

(2012) Alexandra Z. Andreou et al.   RNA Biology

Human tRNASec associates with HeLa membranes, cell lipid liposomes, and synthetic lipid bilayers

(2012) T. Janas et al.   RNA

Coordination of cell growth and division by the ubiquitin–proteasome system

(2012) Jennifer A. Benanti   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Membrane raft disruption results in neuritic retraction prior to neuronal death in cortical neurons

(2012) Shawn N. Whitehead   BioScience Trends

Lipid Rafts and Alzheimer’s Disease: Protein-Lipid Interactions and Perturbation of Signaling

(2012) David A. Hicks et al.   Frontiers in Physiology

Lipid Raft Redox Signaling: Molecular Mechanisms in Health and Disease

(2011) Si Jin et al.   ANTIOXIDANTS & REDOX SIGNALING

The role of VDAC in cell death: Friend or foe?

(2011) Kyle S. McCommis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Measurement of Lipid Nanodomain (Raft) Formation and Size in Sphingomyelin/POPC/Cholesterol Vesicles Shows TX-100 and Transmembrane Helices Increase Domain Size by Coalescing Preexisting Nanodomains But Do Not Induce Domain Formation

(2011) Priyadarshini Pathak et al.   BIOPHYSICAL JOURNAL

Cardiolipin Affects the Supramolecular Organization of ATP Synthase in Mitochondria

(2011) Devrim Acehan et al.   BIOPHYSICAL JOURNAL

Astrocyte - neuron lactate shuttle may boost more ATP supply to the neuron under hypoxic conditions - in silico study supported by in vitro expression data

(2011) Seda Genc et al.   BMC Systems Biology

Human Polycomb protein 2 promotes α-synuclein aggregate formation through covalent SUMOylation

(2011) Yohan Oh et al.   BRAIN RESEARCH

Bacterial genome chimaerism and the origin of mitochondria

(2011) Ankur Abhishek et al.   CANADIAN JOURNAL OF MICROBIOLOGY

p53 Negatively Regulates Transcription of the Pyruvate Dehydrogenase Kinase Pdk2

(2011) T. Contractor et al.   CANCER RESEARCH

Free Radical Lipid Peroxidation: Mechanisms and Analysis

(2011) Huiyong Yin et al.   CHEMICAL REVIEWS

Arrangement of electron transport chain components in bovine mitochondrial supercomplex I1III2IV1

(2011) Thorsten Althoff et al.   EMBO JOURNAL

Lipid matrix plays a role in Abeta fibril kinetics and morphology

(2011) Marc-Antoine Sani et al.   FEBS LETTERS

The Dbp5 cycle at the nuclear pore complex during mRNA export I: dbp5 mutants with defects in RNA binding and ATP hydrolysis define key steps for Nup159 and Gle1

(2011) C. A. Hodge et al.   GENES & DEVELOPMENT

Shared and unique properties of ubiquitin and SUMO interaction networks in DNA repair

(2011) S. J. L. van Wijk et al.   GENES & DEVELOPMENT

Regulation of the Dbp5 ATPase cycle in mRNP remodeling at the nuclear pore: a lively new paradigm for DEAD-box proteins

(2011) S. Ledoux et al.   GENES & DEVELOPMENT

The Dbp5 cycle at the nuclear pore complex during mRNA export II: nucleotide cycling and mRNP remodeling by Dbp5 are controlled by Nup159 and Gle1

(2011) K. N. Noble et al.   GENES & DEVELOPMENT

Regulation of the Fanconi anemia pathway by a SUMO-like delivery network

(2011) K. Yang et al.   GENES & DEVELOPMENT

Rotation and structure of FoF1-ATP synthase

(2011) D. Okuno et al.   JOURNAL OF BIOCHEMISTRY

Primary Role for Endoplasmic Reticulum-bound Ribosomes in Cellular Translation Identified by Ribosome Profiling

(2011) David W. Reid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sumoylation inhibits α-synuclein aggregation and toxicity

(2011) Petranka Krumova et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial ATP synthase: architecture, function and pathology

(2011) An I. Jonckheere et al.   JOURNAL OF INHERITED METABOLIC DISEASE

p53 Requires an Intact C-Terminal Domain for DNA Binding and Transactivation

(2011) Hyunjung Kim et al.   JOURNAL OF MOLECULAR BIOLOGY

Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases

(2011) N. M. Kanaan et al.   JOURNAL OF NEUROSCIENCE

Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations

(2011) Carmen Venegas et al.   JOURNAL OF PINEAL RESEARCH

Stimulation and clustering of cytochrome b5 reductase in caveolin-rich lipid microdomains is an early event in oxidative stress-mediated apoptosis of cerebellar granule neurons

(2011) Alejandro K. Samhan-Arias et al.   Journal of Proteomics

Melatonin Induces Apoptotic Cell Death via p53 in LNCaP Cells

(2011) Chi Hyun Kim et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Are Hydrotropes Distinct from Surfactants?

(2011) Marios Hopkins Hatzopoulos et al.   LANGMUIR

Nanotechnologies for Alzheimer's disease: diagnosis, therapy, and safety issues

(2011) Davide Brambilla et al.   Nanomedicine-Nanotechnology Biology and Medicine

Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

(2011) Jie Xu et al.   Nature Chemical Biology

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Molecular aspects of bacterial pH sensing and homeostasis

(2011) Terry A. Krulwich et al.   NATURE REVIEWS MICROBIOLOGY

Effect of melatonin on α-synuclein self-assembly and cytotoxicity

(2011) Kenjiro Ono et al.   NEUROBIOLOGY OF AGING

Dynamic association of tau with neuronal membranes is regulated by phosphorylation

(2011) Amy M. Pooler et al.   NEUROBIOLOGY OF AGING

Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation

(2011) R Santoro et al.   ONCOGENE

NADPH Oxidase-Mediated Redox Signaling: Roles in Cellular Stress Response, Stress Tolerance, and Tissue Repair

(2011) F. Jiang et al.   PHARMACOLOGICAL REVIEWS

On the direct scavenging activity of melatonin towards hydroxyl and a series of peroxyl radicals

(2011) Annia Galano   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes

(2011) C. P. Brangwynne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The emerging role of RNA in the regulation of gene transcription in human cells

(2011) Kevin V. Morris   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Stress of Protein Misfolding: From Single Cells to Multicellular Organisms

(2011) T. Gidalevitz et al.   Cold Spring Harbor Perspectives in Biology

Membrane Organization and Lipid Rafts

(2011) K. Simons et al.   Cold Spring Harbor Perspectives in Biology

Mitochondrial F1Fo-ATP synthase translocates to cell surface in hepatocytes and has high activity in tumor-like acidic and hypoxic environment

(2010) Zhan Ma et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

The role of p53 in cell metabolism

(2010) Xing-ding Zhang et al.   ACTA PHARMACOLOGICA SINICA

Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death

(2010) Mariana Pehar et al.   AGING CELL

DEAD-box helicases: Posttranslational regulation and function

(2010) Eric A. Gustafson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Functional implications of the association of tau with the plasma membrane

(2010) Amy M. Pooler et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Lipid rafts: Keys to neurodegeneration

(2010) Cara-Lynne Schengrund   BRAIN RESEARCH BULLETIN

Targets and consequences of protein SUMOylation in neurons

(2010) Kevin A. Wilkinson et al.   BRAIN RESEARCH REVIEWS

Caveolae, caveolins, and cavins: complex control of cellular signalling and inflammation

(2010) J. H. Chidlow et al.   CARDIOVASCULAR RESEARCH

Neuronal cell surface ATP synthase mediates synthesis of extracellular ATP and regulation of intracellular pH

(2010) San-Li Xing et al.   CELL BIOLOGY INTERNATIONAL

RNA and transcriptional modulation of gene expression

(2010) Peter G. Hawkins et al.   CELL CYCLE

Cardiolipin Remodeling by ALCAT1 Links Oxidative Stress and Mitochondrial Dysfunction to Obesity

(2010) Jia Li et al.   Cell Metabolism

Tau in Alzheimer Disease and Related Tauopathies

(2010) K. Iqbal et al.   Current Alzheimer Research

Anti-Amyloidogenic and Anti-Apoptotic Role of Melatonin in Alzheimer Disease

(2010) Hongwen He et al.   Current Neuropharmacology

Voltage-dependent anion-selective channel (VDAC) in the plasma membrane

(2010) Vito De Pinto et al.   FEBS LETTERS

Lipid rafts and clusters of apoptotic signaling molecule-enriched rafts in cancer therapy

(2010) Faustino Mollinedo et al.   Future Oncology

Epigenetics and gene expression

(2010) E R Gibney et al.   HEREDITY

Nuclear Tau, a Key Player in Neuronal DNA Protection

(2010) Audrey Sultan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiolipin: characterization of distinct oxidized molecular species

(2010) Junhwan Kim et al.   JOURNAL OF LIPID RESEARCH

The Evolution of Fatty Acid Desaturases and Cytochrome b5 in Eukaryotes

(2010) Cene Gostinčar et al.   JOURNAL OF MEMBRANE BIOLOGY

Voltage-dependent anion channel as a resident protein of lipid rafts: post-transductional regulation by estrogens and involvement in neuronal preservation against Alzheimer’s disease

(2010) Jose Luis Herrera et al.   JOURNAL OF NEUROCHEMISTRY

SYMPOSIUM REVIEW: Lipid microdomains and the regulation of ion channel function

(2010) Caroline Dart   JOURNAL OF PHYSIOLOGY-LONDON

L-type calcium channels and cytochrome b5 reductase are components of protein complexes tightly associated with lipid rafts microdomains of the neuronal plasma membrane

(2010) Dorinda Marques-da-Silva et al.   Journal of Proteomics

Melatonin Induces Akt Phosphorylation through Melatonin Receptor- and PI3K-Dependent Pathways in Primary Astrocytes

(2010) Pil-Jae Kong et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Effect of Cholesterol on Electrostatics in Lipid−Protein Films of a Pulmonary Surfactant

(2010) Eric Finot et al.   LANGMUIR

Multiplex SILAC Analysis of a Cellular TDP-43 Proteinopathy Model Reveals Protein Inclusions Associated with SUMOylation and Diverse Polyubiquitin Chains

(2010) Nicholas T. Seyfried et al.   MOLECULAR & CELLULAR PROTEOMICS

ATP-Dependent Steps in the Binding of Ubiquitin Conjugates to the 26S Proteasome that Commit to Degradation

(2010) Andreas Peth et al.   MOLECULAR CELL

Grand Challenge Commentary: RNA epigenetics?

(2010) Chuan He   Nature Chemical Biology

Overexpression of Fto leads to increased food intake and results in obesity

(2010) Chris Church et al.   NATURE GENETICS

Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets

(2010) Lynn Bedford et al.   NATURE REVIEWS DRUG DISCOVERY

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue

(2010) Liqun Liu-Yesucevitz et al.   PLoS One

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

(2010) W. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial oxidative phosphorylation system is recruited to detergent-resistant lipid rafts during myogenesis

(2010) Bong-Woo Kim et al.   PROTEOMICS

p53 post-translational modification: deregulated in tumorigenesis

(2010) Chao Dai et al.   TRENDS IN MOLECULAR MEDICINE

The Origins of the RNA World

(2010) M. P. Robertson et al.   Cold Spring Harbor Perspectives in Biology

The Plasma Membrane Ca2+ ATPase and the Plasma Membrane Sodium Calcium Exchanger Cooperate in the Regulation of Cell Calcium

(2010) M. Brini et al.   Cold Spring Harbor Perspectives in Biology

Protein Folding in the Cytoplasm and the Heat Shock Response

(2010) R. M. Vabulas et al.   Cold Spring Harbor Perspectives in Biology

Transcriptional Regulation by P53

(2010) R. Beckerman et al.   Cold Spring Harbor Perspectives in Biology

DEAD-box proteins as RNA helicases and chaperones

(2010) Inga Jarmoskaite et al.   Wiley Interdisciplinary Reviews-RNA

Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome

(2009) Daniel Finley   Annual Review of Biochemistry

Cardiolipin membrane domains in prokaryotes and eukaryotes

(2009) Eugenia Mileykovskaya et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The mechanism of ATP-dependent RNA unwinding by DEAD box proteins

(2009) Manuel Hilbert et al.   BIOLOGICAL CHEMISTRY

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

Role of cardiolipin peroxidation and Ca2+ in mitochondrial dysfunction and disease

(2009) Giuseppe Paradies et al.   CELL CALCIUM

Ubiquitin-independent p53 proteasomal degradation

(2009) P Tsvetkov et al.   CELL DEATH AND DIFFERENTIATION

Cardiolipin-enriched raft-like microdomains are essential activating platforms for apoptotic signals on mitochondria

(2009) Maurizio Sorice et al.   FEBS LETTERS

Antioxidant Activity of Vitamin E and Trolox: Understanding of the Factors that Govern Lipid Peroxidation Studies In Vitro

(2009) Marlene Lúcio et al.   Food Biophysics

Lipid peroxidation: Physiological levels and dual biological effects

(2009) Etsuo Niki   FREE RADICAL BIOLOGY AND MEDICINE

Melatonin inhibits cardiolipin peroxidation in mitochondria and prevents the mitochondrial permeability transition and cytochrome c release

(2009) Giuseppe Petrosillo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis

(2009) G. S. Pesiridis et al.   HUMAN MOLECULAR GENETICS

Oxidative Stress Increases the Number of Stress Granules in Senescent Cells and Triggers a Rapid Decrease in p21waf1/cip1Translation

(2009) Xian Jin Lian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity

(2009) Brian S. Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integral membrane proteins Brr6 and Apq12 link assembly of the nuclear pore complex to lipid homeostasis in the endoplasmic reticulum

(2009) C. A. Hodge et al.   JOURNAL OF CELL SCIENCE

Mutations of FUS gene in sporadic amyotrophic lateral sclerosis

(2009) L. Corrado et al.   JOURNAL OF MEDICAL GENETICS

SUMOylation participates in induction of ischemic tolerance

(2009) Yang ja Lee et al.   JOURNAL OF NEUROCHEMISTRY

Eukaryotic Stress Granules: The Ins and Outs of Translation

(2009) J. Ross Buchan et al.   MOLECULAR CELL

Ribosomal Protein S7 Is Both a Regulator and a Substrate of MDM2

(2009) Yan Zhu et al.   MOLECULAR CELL

Principles of ubiquitin and SUMO modifications in DNA repair

(2009) Steven Bergink et al.   NATURE

The evolutionary consequences of erroneous protein synthesis

(2009) D. Allan Drummond et al.   NATURE REVIEWS GENETICS

Analysis of FUS gene mutation in familial amyotrophic lateral sclerosis within an Italian cohort

(2009) N. Ticozzi et al.   NEUROLOGY

Nuclear envelope and nuclear pore complex structure and organization in tobacco BY-2 cells

(2009) Jindriska Fiserova et al.   PLANT JOURNAL

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

(2009) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

(2009) H. Imamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metazoan stress granule assembly is mediated by P-eIF2 -dependent and -independent mechanisms

(2009) N. G. Farny et al.   RNA

Posttranslational Modification of p53: Cooperative Integrators of Function

(2009) D. W. Meek et al.   Cold Spring Harbor Perspectives in Biology

A Mouse Model for the Metabolic Effects of the Human Fat Mass and Obesity Associated FTO Gene

(2009) Chris Church et al.   PLoS Genetics

Structural Biology of the Tumor Suppressor p53

(2008) Andreas C. Joerger et al.   Annual Review of Biochemistry

Lipid Rafts and Caveolae and Their Role in Compartmentation of Redox Signaling

(2008) Hemal H. Patel et al.   ANTIOXIDANTS & REDOX SIGNALING

Sumoylation of amyloid precursor protein negatively regulates Aβ aggregate levels

(2008) Yu-Qian Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SUMO, hypoxia and the regulation of metabolism: Figure 1

(2008) Terence A. Agbor et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Structural and functional characterization of FoF1-ATP synthase on the extracellular surface of rat hepatocytes

(2008) Roberto Mangiullo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Lipid Localization in Bacterial Cells through Curvature-Mediated Microphase Separation

(2008) Ranjan Mukhopadhyay et al.   BIOPHYSICAL JOURNAL

Membrane Deformation under Local pH Gradient: Mimicking Mitochondrial Cristae Dynamics

(2008) Nada Khalifat et al.   BIOPHYSICAL JOURNAL

Recessive congenital methaemoglobinaemia: cytochrome b5reductase deficiency

(2008) Melanie J. Percy et al.   BRITISH JOURNAL OF HAEMATOLOGY

Cardiolipin, the heart of mitochondrial metabolism

(2008) R. H. Houtkooper et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cardiac-Specific Overexpression of Caveolin-3 Induces Endogenous Cardiac Protection by Mimicking Ischemic Preconditioning

(2008) Yasuo M. Tsutsumi et al.   CIRCULATION

Hyperphosphorylation of Microtubule-Associated Protein Tau: A Promising Therapeutic Target for Alzheimer Disease

(2008) C.-X. Gong et al.   CURRENT MEDICINAL CHEMISTRY

Association of variants in the fat mass and obesity associated (FTO) gene with polycystic ovary syndrome

(2008) T. M. Barber et al.   DIABETOLOGIA

Dimer ribbons of ATP synthase shape the inner mitochondrial membrane

(2008) Mike Strauss et al.   EMBO JOURNAL

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

(2008) Didier Soulat et al.   EMBO JOURNAL

Nuclear pore complex assembly through the cell cycle: Regulation and membrane organization

(2008) Wolfram Antonin et al.   FEBS LETTERS

Cardiolipin provides an essential activating platform for caspase-8 on mitochondria

(2008) Francois Gonzalvez et al.   JOURNAL OF CELL BIOLOGY

Shaping the endoplasmic reticulum into the nuclear envelope

(2008) D. J. Anderson et al.   JOURNAL OF CELL SCIENCE

Niacin inhibits surface expression of ATP synthase β chain in HepG2 cells: implications for raising HDL

(2008) Lin-Hua Zhang et al.   JOURNAL OF LIPID RESEARCH

The challenge of lipid rafts

(2008) Linda J. Pike   JOURNAL OF LIPID RESEARCH

Clustering of plasma membrane-bound cytochrome b5 reductase within ‘lipid raft’ microdomains of the neuronal plasma membrane

(2008) Alejandro K. Samhan-Arias et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Lipid Microdomains in Cell Nucleus

(2008) Giacomo Cascianelli et al.   MOLECULAR BIOLOGY OF THE CELL

An update on products and mechanisms of lipid peroxidation

(2008) Claus Schneider   MOLECULAR NUTRITION & FOOD RESEARCH

Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

(2008) Kyoko Arimoto et al.   NATURE CELL BIOLOGY

p53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation

(2008) Keiko Kawauchi et al.   NATURE CELL BIOLOGY

A complex barcode underlies the heterogeneous response of p53 to stress

(2008) Fiona Murray-Zmijewski et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction

(2008) Hwan-Ching Tai et al.   NATURE REVIEWS NEUROSCIENCE

The p53 family and programmed cell death

(2008) E C Pietsch et al.   ONCOGENE

Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain

(2008) M. Wells et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cooperative binding of ATP and RNA induces a closed conformation in a DEAD box RNA helicase

(2008) B. Theissen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA