The biological function of m6A demethylase ALKBH5 and its role in human disease
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The biological function of m6A demethylase ALKBH5 and its role in human disease
Authors
Keywords
-
Journal
Cancer Cell International
Volume 20, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-07-28
DOI
10.1186/s12935-020-01450-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The N 6 -methyladenosine (m6 A) erasers alkylation repair homologue 5 (ALKBH5) and fat mass and obesity-associated protein (FTO) are prognostic biomarkers in patients with clear cell renal carcinoma
- (2020) Alexander Strick et al. BJU INTERNATIONAL
- BMP2 Modified by the m6A Demethylation Enzyme ALKBH5 in the Ossification of the Ligamentum Flavum Through the AKT Signaling Pathway
- (2020) Hai-Feng Wang et al. CALCIFIED TISSUE INTERNATIONAL
- m6A demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling
- (2020) Bo Tang et al. Molecular Cancer
- m6A demethylase ALKBH5 inhibits tumor growth and metastasis by reducing YTHDFs-mediated YAP expression and inhibiting miR-107/LATS2–mediated YAP activity in NSCLC
- (2020) Dan Jin et al. Molecular Cancer
- An oncopeptide regulates m6A recognition by the m6A reader IGF2BP1 and tumorigenesis
- (2020) Song Zhu et al. Nature Communications
- METTL3 and ALKBH5 oppositely regulate m6A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes
- (2019) Huiwen Song et al. Autophagy
- ALKBH5 inhibited autophagy of epithelial ovarian cancer through miR-7 and BCL-2
- (2019) Hongtao Zhu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The role of m6A RNA methylation in human cancer
- (2019) Xiao-Yu Chen et al. Molecular Cancer
- ALKBH5 promotes invasion and metastasis of gastric cancer by decreasing methylation of the lncRNA NEAT1
- (2019) Jun Zhang et al. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- KIAA1429 acts as an oncogenic factor in breast cancer by regulating CDK1 in an N6-methyladenosine-independent manner
- (2019) Jia-Yi Qian et al. ONCOGENE
- A Review in Research Progress Concerning m6A Methylation and Immunoregulation
- (2019) Caiyan Zhang et al. Frontiers in Immunology
- ALKBH5 Holds Prognostic Values and Inhibits the Metastasis of Colon Cancer
- (2019) Peipei Yang et al. PATHOLOGY & ONCOLOGY RESEARCH
- The interplay between m6A RNA methylation and noncoding RNA in cancer
- (2019) Shuai Ma et al. Journal of Hematology & Oncology
- METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing
- (2019) Xiaoxiang Chen et al. MOLECULAR THERAPY
- Multiple Functions and Mechanisms Underlying the Role of METTL3 in Human Cancers
- (2019) Wenhui Zheng et al. Frontiers in Oncology
- Cancer stem cells in triple-negative breast cancer: a potential target and prognostic marker
- (2018) Christopher J O'Conor et al. Biomarkers in Medicine
- 1H, 15N, 13C backbone resonance assignment of human Alkbh5
- (2018) Jeffrey A. Purslow et al. Biomolecular NMR Assignments
- ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation
- (2018) Yuan He et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- ALKBH5-induced demethylation of mono- and dimethylated adenosine
- (2018) Timm T. Ensfelder et al. CHEMICAL COMMUNICATIONS
- Active Site Breathing of Human Alkbh5 Revealed by Solution NMR and Accelerated Molecular Dynamics
- (2018) Jeffrey A. Purslow et al. BIOPHYSICAL JOURNAL
- The evolving concept of liver cancer stem cells
- (2017) Kouki Nio et al. Molecular Cancer
- Dynamic m6A modification regulates local translation of mRNA in axons
- (2017) Jun Yu et al. NUCLEIC ACIDS RESEARCH
- ALKBH5-dependent m6A demethylation controls splicing and stability of long 3′-UTR mRNAs in male germ cells
- (2017) Chong Tang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The DEAD-Box RNA Helicase DDX3 Interacts with m6A RNA Demethylase ALKBH5
- (2017) Abdullah Shah et al. Stem Cells International
- Cancer Stem Cells: Basic Concepts and Therapeutic Implications
- (2016) Dany Nassar et al. Annual Review of Pathology-Mechanisms of Disease
- Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells
- (2016) Chuanzhao Zhang et al. Oncotarget
- N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5
- (2016) Shui Zou et al. Scientific Reports
- Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-strandedN6-Methyladenosine RNA Demethylation
- (2014) Chao Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal Structures of the Human RNA Demethylase Alkbh5 Reveal Basis for Substrate Recognition
- (2014) Chong Feng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation
- (2014) WeiShen Aik et al. NUCLEIC ACIDS RESEARCH
- Crystallization and preliminary X-ray diffraction of the RNA demethylase ALKBH5
- (2013) Bin Zhou et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
- (2012) Guanqun Zheng et al. MOLECULAR CELL
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started