Sumo and the cellular stress response

c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4

(2015) Román González-Prieto et al.   CELL CYCLE

Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes

(2015) Pierre Chymkowitch et al.   GENOME RESEARCH

The S. cerevisiae SUMO stress response is a conjugation–deconjugation cycle that targets the transcription machinery

(2015) Megan C. Lewicki et al.   Journal of Proteomics

System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome Stability

(2015) Zhenyu Xiao et al.   MOLECULAR & CELLULAR PROTEOMICS

SUMO-mediated regulation of DNA damage repair and responses

(2015) Prabha Sarangi et al.   TRENDS IN BIOCHEMICAL SCIENCES

SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage

(2015) Ivo A. Hendriks et al.   Cell Reports

Two distinct promoter architectures centered on dynamic nucleosomes control ribosomal protein gene transcription

(2014) Britta Knight et al.   GENES & DEVELOPMENT

Sumoylation regulates ER stress response by modulating calreticulin gene expression in XBP-1-dependent mode in Caenorhabditis elegans

(2014) Yunki Lim et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Important Role of SUMOylation of Spliceosome Factors in Prostate Cancer Cells

(2014) Donghua Wen et al.   JOURNAL OF PROTEOME RESEARCH

Uncovering global SUMOylation signaling networks in a site-specific manner

(2014) Ivo A Hendriks et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Proteome-Wide Identification of SUMO2 Modification Sites

(2014) T. Tammsalu et al.   Science Signaling

Large-scale analysis of lysine SUMOylation by SUMO remnant immunoaffinity profiling

(2014) Frédéric Lamoliatte et al.   Nature Communications

Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans

(2014) Federico Pelisch et al.   Nature Communications

UBC9 Regulates the Stability of XBP1, a Key Transcription Factor Controlling the ER Stress Response

(2013) Aya Uemura et al.   CELL STRUCTURE AND FUNCTION

End-joining inhibition at telomeres requires the translocase and polySUMO-dependent ubiquitin ligase Uls1

(2013) Rachel Lescasse et al.   EMBO JOURNAL

Covalent Small Ubiquitin-like Modifier (SUMO) Modification of Maf1 Protein Controls RNA Polymerase III-dependent Transcription Repression

(2013) Aarti D. Rohira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global analysis of SUMO chain function reveals multiple roles in chromatin regulation

(2013) Tharan Srikumar et al.   JOURNAL OF CELL BIOLOGY

The Nuclear Pore Regulates GAL1 Gene Transcription by Controlling the Localization of the SUMO Protease Ulp1

(2013) Lorane Texari et al.   MOLECULAR CELL

Regulation of DNA Damage Responses by Ubiquitin and SUMO

(2013) Stephen P. Jackson et al.   MOLECULAR CELL

Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation

(2013) Danielle L Swaney et al.   NATURE METHODS

Interplay between viruses and host sumoylation pathways

(2013) Roger D. Everett et al.   NATURE REVIEWS MICROBIOLOGY

The return of the nucleus: transcriptional and epigenetic control of autophagy

(2013) Jens Füllgrabe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of Arabidopsis SUMO-interacting proteins that regulate chromatin activity and developmental transitions

(2013) N. Elrouby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Group Modification and Synergy in the SUMO Pathway as Exemplified in DNA Repair

(2012) Ivan Psakhye et al.   CELL

SENP1 deficiency promotes ER stress-induced apoptosis by increasing XBP1 SUMOylation

(2012) Zhou Jiang et al.   CELL CYCLE

SUMO, a heavyweight player in plant abiotic stress responses

(2012) Pedro Humberto Castro et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A manually curated network of the PML nuclear body interactome reveals an important role for PML-NBs in SUMOylation dynamics

(2012) Ellen Van Damme et al.   International Journal of Biological Sciences

Extensive DNA Damage-Induced Sumoylation Contributes to Replication and Repair and Acts in Addition to the Mec1 Checkpoint

(2012) Catherine A. Cremona et al.   MOLECULAR CELL

SUMO-Specific Protease 1 Is Critical for Early Lymphoid Development through Regulation of STAT5 Activation

(2012) Thang Van Nguyen et al.   MOLECULAR CELL

Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation

(2012) Peter Kolesar et al.   NUCLEIC ACIDS RESEARCH

The Sumo-targeted ubiquitin ligase RNF4 regulates the localization and function of the HTLV-1 oncoprotein Tax

(2011) K. A. Fryrear et al.   BLOOD

Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control

(2011) Robbie Loewith et al.   GENETICS

Human Pathogens and the Host Cell SUMOylation System

(2011) P. Wimmer et al.   JOURNAL OF VIROLOGY

SUMO and SUMOylation in plants

(2011) Hee Jin Park et al.   MOLECULES AND CELLS

Comparative Proteomic Analysis Identifies a Role for SUMO in Protein Quality Control

(2011) M. H. Tatham et al.   Science Signaling

SUMO modification regulates the transcriptional activity of XBP1

(2010) Hui Chen et al.   BIOCHEMICAL JOURNAL

In VivoIdentification of Sumoylation Sites by a Signature Tag and Cysteine-targeted Affinity Purification

(2010) Henri A. Blomster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SUMOylation of the GTPase Rac1 is required for optimal cell migration

(2010) Sonia Castillo-Lluva et al.   NATURE CELL BIOLOGY

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SUMO E3 ligase activity of TRIM proteins

(2010) Y Chu et al.   ONCOGENE

Sumoylation and other ubiquitin-like post-translational modifications in plants

(2010) Kenji Miura et al.   TRENDS IN CELL BIOLOGY

PML Nuclear Bodies

(2010) V. Lallemand-Breitenbach et al.   Cold Spring Harbor Perspectives in Biology

Cdk1 Targets Srs2 to Complete Synthesis-Dependent Strand Annealing and to Promote Recombinational Repair

(2010) Marco Saponaro et al.   PLoS Genetics

Phospho-Regulated SUMO Interaction Modules Connect the SUMO System to CK2 Signaling

(2009) Per Stehmeier et al.   MOLECULAR CELL

Defects in DNA ligase I trigger PCNA ubiquitylation at Lys 107

(2009) Sapna Das-Bradoo et al.   NATURE CELL BIOLOGY

Global Analysis of Cdk1 Substrate Phosphorylation Sites Provides Insights into Evolution

(2009) L. J. Holt et al.   SCIENCE

System-Wide Changes to SUMO Modifications in Response to Heat Shock

(2009) F. Golebiowski et al.   Science Signaling

Small Ubiquitin-related Modifier (SUMO) Binding Determines Substrate Recognition and Paralog-selective SUMO Modification

(2008) Jianmei Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubc9 Sumoylation Regulates SUMO Target Discrimination

(2008) Puck Knipscheer et al.   MOLECULAR CELL

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY

A SIM-ultaneous role for SUMO and ubiquitin

(2008) J. Jefferson P. Perry et al.   TRENDS IN BIOCHEMICAL SCIENCES