ALS-Causing Mutations Significantly Perturb the Self-Assembly and Interaction with Nucleic Acid of the Intrinsically Disordered Prion-Like Domain of TDP-43
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Title
ALS-Causing Mutations Significantly Perturb the Self-Assembly and Interaction with Nucleic Acid of the Intrinsically Disordered Prion-Like Domain of TDP-43
Authors
Keywords
Prions, Aqueous solutions, Amyloid proteins, Fluorescence, NMR spectroscopy, Amyotrophic lateral sclerosis, Hydrogen bonding, Point mutation
Journal
PLOS BIOLOGY
Volume 14, Issue 1, Pages e1002338
Publisher
Public Library of Science (PLoS)
Online
2016-01-07
DOI
10.1371/journal.pbio.1002338
References
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