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Title
Tau in physiology and pathology
Authors
Keywords
-
Journal
NATURE REVIEWS NEUROSCIENCE
Volume 17, Issue 1, Pages 22-35
Publisher
Springer Nature
Online
2015-12-03
DOI
10.1038/nrn.2015.1
References
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Note: Only part of the references are listed.- PART, a distinct tauopathy, different from classical sporadic Alzheimer disease
- (2015) Kurt A. Jellinger et al. ACTA NEUROPATHOLOGICA
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- (2015) Nicole Maphis et al. BRAIN
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- (2015) V. Corsetti et al. HUMAN MOLECULAR GENETICS
- Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau
- (2015) Ismael Santa-Maria et al. JOURNAL OF CLINICAL INVESTIGATION
- Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy
- (2015) Asami Kondo et al. NATURE
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- (2015) Sang-Won Min et al. NATURE MEDICINE
- Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice
- (2015) Meaghan Morris et al. NATURE NEUROSCIENCE
- Spreading of pathology in neurodegenerative diseases: a focus on human studies
- (2015) Johannes Brettschneider et al. NATURE REVIEWS NEUROSCIENCE
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- (2015) Eve Peeraer et al. NEUROBIOLOGY OF DISEASE
- Tau stabilizes microtubules by binding at the interface between tubulin heterodimers
- (2015) Harindranath Kadavath et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms
- (2015) Maxime Derisbourg et al. Scientific Reports
- Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca++ dysregulation
- (2015) Jochen Martin Decker et al. Acta Neuropathologica Communications
- Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau
- (2015) Katja Hochgräfe et al. Acta Neuropathologica Communications
- Are cases with tau pathology occurring in the absence of Aβ deposits part of the AD-related pathological process?
- (2014) Heiko Braak et al. ACTA NEUROPATHOLOGICA
- Primary age-related tauopathy (PART): a common pathology associated with human aging
- (2014) John F. Crary et al. ACTA NEUROPATHOLOGICA
- Tau reduction prevents disease in a mouse model of Dravet syndrome
- (2014) Ania L. Gheyara et al. ANNALS OF NEUROLOGY
- Myelination of the Nervous System: Mechanisms and Functions
- (2014) Klaus-Armin Nave et al. Annual Review of Cell and Developmental Biology
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- (2014) Kristen E. Funk et al. BIOCHEMICAL JOURNAL
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- (2014) Ludovic Collin et al. BRAIN
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- (2014) G. Elif Karagöz et al. CELL
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- (2014) Laura J Blair et al. EXPERT OPINION ON THERAPEUTIC TARGETS
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- (2014) Claire H. Michel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2014) Clara S. R. Grüning et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2014) Katharina Moschner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2014) Joëlle Rosseels et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prion-like Properties of Tau Protein: The Importance of Extracellular Tau as a Therapeutic Target
- (2014) Brandon B. Holmes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2014) Katharina Tepper et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2014) Kaoru Yamada et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2014) Scott A. Yuzwa et al. JOURNAL OF MOLECULAR BIOLOGY
- Activity-Dependent Tau Protein Translocation to Excitatory Synapse Is Disrupted by Exposure to Amyloid-Beta Oligomers
- (2014) M. L. Frandemiche et al. JOURNAL OF NEUROSCIENCE
- Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles
- (2014) D. L. Castillo-Carranza et al. JOURNAL OF NEUROSCIENCE
- Proteostasis and the Aging Proteome in Health and Disease
- (2014) R. I. Morimoto et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial
- (2014) Adam L Boxer et al. LANCET NEUROLOGY
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- (2014) Peng Lei et al. Molecular Neurodegeneration
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- (2014) Günter U. Höglinger et al. MOVEMENT DISORDERS
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- (2014) Marta Fernández-Nogales et al. NATURE MEDICINE
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- (2014) Zhentao Zhang et al. NATURE MEDICINE
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- (2014) Tariq Ahmed et al. NEUROBIOLOGY OF AGING
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- (2014) David W. Sanders et al. NEURON
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- (2014) Julius Bruch et al. PLoS One
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- (2014) Hong-Bin Luo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2014) J. Giustiniani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2013) Hans Zempel et al. EMBO JOURNAL
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- (2013) J. K. Holth et al. JOURNAL OF NEUROSCIENCE
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- (2013) S. L. DeVos et al. JOURNAL OF NEUROSCIENCE
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- (2013) Einar M. Sigurdsson Neurodegenerative Diseases
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- (2013) Kiran Yanamandra et al. NEURON
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- (2013) T. Kimura et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
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- (2013) Sefika Ozcelik et al. PLoS One
- Tau Passive Immunotherapy in Mutant P301L Mice: Antibody Affinity versus Specificity
- (2013) Cristina d’Abramo et al. PLoS One
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- (2013) Chang Liu et al. PLoS One
- Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
- (2013) B. B. Holmes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
- (2013) E.-M. Mandelkow et al. Cold Spring Harbor Perspectives in Medicine
- Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau
- (2012) Ann Van der Jeugd et al. ACTA NEUROPATHOLOGICA
- Lack of Tau Proteins Rescues Neuronal Cell Death and Decreases Amyloidogenic Processing of APP in APP/PS1 Mice
- (2012) Karelle Leroy et al. AMERICAN JOURNAL OF PATHOLOGY
- Degradation of tau protein by autophagy and proteasomal pathways: Figure 1
- (2012) Yipeng Wang et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Loss of fused in sarcoma (FUS) promotes pathological Tau splicing
- (2012) Denise Orozco et al. EMBO REPORTS
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- (2012) Cristian A. Lasagna-Reeves et al. FASEB JOURNAL
- Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease
- (2012) Michael H. Yan et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2012) Daniah Trabzuni et al. HUMAN MOLECULAR GENETICS
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- (2012) Giovanni Coppola et al. HUMAN MOLECULAR GENETICS
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- (2012) Chronis Fatouros et al. HUMAN MOLECULAR GENETICS
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- (2012) Siddhartha Mondragón-Rodríguez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Qi Zhong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Katharina Flach et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Celeste M. Karch et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Y. Yoshiyama et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export
- (2012) Peng Lei et al. NATURE MEDICINE
- The fuzzy coat of pathological human Tau fibrils is a two-layered polyelectrolyte brush
- (2012) Susanne Wegmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective tau tyrosine nitration in non-AD tauopathies
- (2011) Juan F. Reyes et al. ACTA NEUROPATHOLOGICA
- Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration
- (2011) Xiaoyu Li et al. EMBO JOURNAL
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- (2011) Pascal Y. Smith et al. HUMAN MOLECULAR GENETICS
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- (2011) Jing L. Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2011) Dennis W. Dickson et al. JOURNAL OF MOLECULAR NEUROSCIENCE
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- (2011) N. M. Kanaan et al. JOURNAL OF NEUROSCIENCE
- Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant
- (2011) A. Sydow et al. JOURNAL OF NEUROSCIENCE
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- (2011) K. Yamada et al. JOURNAL OF NEUROSCIENCE
- Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
- (2011) Stuart A. Sievers et al. NATURE
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- (2011) Ulrike Krüger et al. NEUROBIOLOGY OF AGING
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- (2011) Ludovic Martin et al. NEUROCHEMISTRY INTERNATIONAL
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- (2010) Lars M. Ittner et al. CELL
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- (2010) Audrey Sultan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) K. R. Brunden et al. JOURNAL OF NEUROSCIENCE
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- (2010) H. Zempel et al. JOURNAL OF NEUROSCIENCE
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- (2010) Alix de Calignon et al. NATURE
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- (2010) Sarika Garg et al. NEUROBIOLOGY OF AGING
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- (2010) Sang-Won Min et al. NEURON
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- (2010) Brian R. Hoover et al. NEURON
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- (2009) Stephanie J. Adams et al. AMERICAN JOURNAL OF PATHOLOGY
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- (2009) Alberto Gómez-Ramos et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
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- (2009) Almudena Fuster-Matanzo et al. FEBS LETTERS
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- (2009) Xiao-Ping Hong et al. HIPPOCAMPUS
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- (2009) Chris R. Guthrie et al. HUMAN MOLECULAR GENETICS
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- (2009) Yipeng Wang et al. HUMAN MOLECULAR GENETICS
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- (2009) Lars M. Ittner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) I. T. Whiteman et al. JOURNAL OF NEUROSCIENCE
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- (2009) Walter Nickel et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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- (2009) Diane P. Hanger et al. TRENDS IN MOLECULAR MEDICINE
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- (2009) Marco D Mukrasch et al. PLOS BIOLOGY
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- (2008) C. Hugh Reynolds et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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