Ubiquitin and Proteasomes in Transcription

Signals and Combinatorial Functions of Histone Modifications

(2011) Tamaki Suganuma et al.   Annual Review of Biochemistry

AAA+ Proteases: ATP-Fueled Machines of Protein Destruction

(2011) Robert T. Sauer et al.   Annual Review of Biochemistry

The role of FACT in making and breaking nucleosomes

(2011) Tim Formosa   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Promoter context determines the role of proteasome in ligand-dependent occupancy of retinoic acid responsive elements

(2011) Aliaa Higazi et al.   Epigenetics

Lys-63-specific Deubiquitination of SDS3 by USP17 Regulates HDAC Activity

(2011) Suresh Ramakrishna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

H3K4 Trimethylation by Set1 Promotes Efficient Termination by the Nrd1-Nab3-Sen1 Pathway

(2011) N. Terzi et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone H2B ubiquitylation and H3 lysine 4 methylation prevent ectopic silencing of euchromatic loci important for the cellular response to heat

(2011) Amy Leung et al.   MOLECULAR BIOLOGY OF THE CELL

The TFIIH Subunit Tfb3 Regulates Cullin Neddylation

(2011) Gwenaël Rabut et al.   MOLECULAR CELL

Recruitment of TIF1γ to Chromatin via Its PHD Finger-Bromodomain Activates Its Ubiquitin Ligase and Transcriptional Repressor Activities

(2011) Eleonora Agricola et al.   MOLECULAR CELL

RNF20 Inhibits TFIIS-Facilitated Transcriptional Elongation to Suppress Pro-oncogenic Gene Expression

(2011) Efrat Shema et al.   MOLECULAR CELL

WAC, a Functional Partner of RNF20/40, Regulates Histone H2B Ubiquitination and Gene Transcription

(2011) Feng Zhang et al.   MOLECULAR CELL

Cdc48/p97 Mediates UV-Dependent Turnover of RNA Pol II

(2011) Rati Verma et al.   MOLECULAR CELL

The RING Finger Protein MSL2 in the MOF Complex Is an E3 Ubiquitin Ligase for H2B K34 and Is Involved in Crosstalk with H3 K4 and K79 Methylation

(2011) Lipeng Wu et al.   MOLECULAR CELL

Ligand-Dependent Degradation of SRC-1 Is Pivotal for Progesterone Receptor Transcriptional Activity

(2011) Larbi Amazit et al.   MOLECULAR ENDOCRINOLOGY

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

(2011) Beat Fierz et al.   Nature Chemical Biology

Constructing and decoding unconventional ubiquitin chains

(2011) Christian Behrends et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dia2 Controls Transcription by Mediating Assembly of the RSC Complex

(2011) Edward J. Andress et al.   PLoS One

Cdc48: a power machine in protein degradation

(2011) Alexandra Stolz et al.   TRENDS IN BIOCHEMICAL SCIENCES

Rad23 escapes degradation because it lacks a proteasome initiation region

(2011) Susan Fishbain et al.   Nature Communications

A lysine-rich region in Dot1p is crucial for direct interaction with H2B ubiquitylation and high level methylation of H3K79

(2010) Seunghee Oh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proteolytic and non-proteolytic roles of ubiquitin and the ubiquitin proteasome system in transcriptional regulation

(2010) Kavita P. Bhat et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Proteolytic Instability and the Action of Nonclassical Transcriptional Activators

(2010) Xin Wang et al.   CURRENT BIOLOGY

The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process

(2010) Pierre Chymkowitch et al.   EMBO JOURNAL

Histone H2B ubiquitination and beyond

(2010) Mahesh B. Chandrasekharan et al.   Epigenetics

The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome

(2010) E. J. Song et al.   GENES & DEVELOPMENT

Ubiquitin-mediated mRNP dynamics and surveillance prior to budding yeast mRNA export

(2010) N. Iglesias et al.   GENES & DEVELOPMENT

Proteasomal degradation of myocardin is required for its transcriptional activity in vascular smooth muscle cells

(2010) Hao Yin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cks1, Cdk1, and the 19S Proteasome Collaborate To Regulate Gene Induction-Dependent Nucleosome Eviction in Yeast

(2010) S. Chaves et al.   MOLECULAR AND CELLULAR BIOLOGY

Mammalian SWI/SNF-A Subunit BAF250/ARID1 Is an E3 Ubiquitin Ligase That Targets Histone H2B

(2010) X. S. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Novel trans-Tail Regulation of H2B Ubiquitylation and H3K4 Methylation by the N Terminus of Histone H2A

(2010) S. Zheng et al.   MOLECULAR AND CELLULAR BIOLOGY

Structure and Basal Transcription Complex of RNA Polymerase II Core Promoters in the Mammalian Genome: An Overview

(2010) Martina Baumann et al.   MOLECULAR BIOTECHNOLOGY

Taf1 Regulates Pax3 Protein by Monoubiquitination in Skeletal Muscle Progenitors

(2010) Stéphane C. Boutet et al.   MOLECULAR CELL

A Transcriptional Activator Is Part of an SCF Ubiquitin Ligase to Control Degradation of Its Cofactors

(2010) Ikram Ouni et al.   MOLECULAR CELL

Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation

(2010) Champak Chatterjee et al.   Nature Chemical Biology

Combined chemical and genetic approach to inhibit proteolysis by the proteasome

(2010) Galen A. Collins et al.   YEAST

Roles for common MLL/COMPASS subunits and the 19S proteasome in regulating CIITA pIV and MHC class II gene expression and promoter methylation

(2010) Olivia I Koues et al.   Epigenetics & Chromatin

Structure–Activity Analysis of Semisynthetic Nucleosomes: Mechanistic Insights into the Stimulation of Dot1L by Ubiquitylated Histone H2B

(2009) Robert K. McGinty et al.   ACS Chemical Biology

Roles of proteasomal 19S regulatory particles in promoter loading of thyroid hormone receptor

(2009) Tetsurou Satoh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The 19S proteasome positively regulates histone methylation at cytokine inducible genes

(2009) Olivia I. Koues et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

RAD6-Mediated Transcription-Coupled H2B Ubiquitylation Directly Stimulates H3K4 Methylation in Human Cells

(2009) Jaehoon Kim et al.   CELL

Proteasome-Mediated Turnover of the Transcription Coactivator NPR1 Plays Dual Roles in Regulating Plant Immunity

(2009) Steven H. Spoel et al.   CELL

Damage control: DNA repair, transcription, and the ubiquitin–proteasome system

(2009) Anne Daulny et al.   DNA REPAIR

H3 lysine 4 di- and tri-methylation deposited by cryptic transcription attenuates promoter activation

(2009) Marina Pinskaya et al.   EMBO JOURNAL

Revisiting the COP9 signalosome as a transcriptional regulator

(2009) Daniel A Chamovitz   EMBO REPORTS

Tat-Binding Protein-1 (TBP-1), an ATPase of 19S Regulatory Particles of the 26S Proteasome, Enhances Androgen Receptor Function in Cooperation with TBP-1-Interacting Protein/Hop2

(2009) Tetsurou Satoh et al.   ENDOCRINOLOGY

GCN5 is a required cofactor for a ubiquitin ligase that targets NF- B/RelA

(2009) X. Mao et al.   GENES & DEVELOPMENT

Non-proteolytic Regulation of p53-mediated Transcription through Destabilization of the Activator·Promoter Complex by the Proteasomal ATPases

(2009) Young-Chan Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The 19 S Proteasome Subcomplex Establishes a Specific Protein Interaction Network at the Promoter for Stimulated Transcriptional Initiationin Vivo

(2009) Shivani Malik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Transcription Factor Atf1 Binds and Activates the APC/C Ubiquitin Ligase in Fission Yeast

(2009) Aslihan Ors et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

No Splicing, No Dicing: Non-proteolytic Roles of the Ubiquitin-Proteasome System in Transcription

(2009) Thomas Kodadek   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Bre1-Paf1 Complex Interactions and RING Finger-independent Bre1-Rad6 Interactions Mediate Histone H2B Ubiquitylation in Yeast

(2009) Jaehoon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The 19S ATPase S6a (S6′/TBP1) Regulates the Transcription Initiation of Class II Transactivator

(2009) Agnieszka D. Truax et al.   JOURNAL OF MOLECULAR BIOLOGY

Proteasome Subunits Relocalize during Human Cytomegalovirus Infection, and Proteasome Activity Is Necessary for Efficient Viral Gene Transcription

(2009) K. Tran et al.   JOURNAL OF VIROLOGY

A ubiquitin-selective AAA-ATPase mediates transcriptional switching by remodelling a repressor–promoter DNA complex

(2009) Alexander J. Wilcox et al.   NATURE CELL BIOLOGY

Breaking the chains: structure and function of the deubiquitinases

(2009) David Komander et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ubiquitination of histone H2B regulates chromatin dynamics by enhancing nucleosome stability

(2009) M. B. Chandrasekharan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of mono-ubiquitinated Smad4 in the formation of Smad transcriptional complexes

(2008) Bei Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proteasomal ATPases are associated with rDNA: The ubiquitin proteasome system plays a direct role in RNA polymerase I transcription

(2008) Károly Fátyol et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Histone chaperones in nucleosome eviction and histone exchange

(2008) Young-Jun Park et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

An Arabidopsis F-box protein acts as a transcriptional co-factor to regulate floral development

(2008) E. Chae et al.   DEVELOPMENT

Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Fumiyo Ikeda et al.   EMBO REPORTS

Activation Domain-dependent Monoubiquitylation of Gal4 Protein Is Essential for Promoter Bindingin Vivo

(2008) Chase T. Archer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mdm2 Ubiquitin Ligase Enhances Transcriptional Activity of Human Papillomavirus E2

(2008) N. Gammoh et al.   JOURNAL OF VIROLOGY

Regulation of Acetylation at the Major Histocompatibility Complex Class II Proximal Promoter by the 19S Proteasomal ATPase Sug1

(2008) O. I. Koues et al.   MOLECULAR AND CELLULAR BIOLOGY

Polyubiquitylation of Histone H2B

(2008) Fuqiang Geng et al.   MOLECULAR BIOLOGY OF THE CELL

Histone Ubiquitination: Triggering Gene Activity

(2008) Vikki M. Weake et al.   MOLECULAR CELL

H2B Ubiquitylation Plays a Role in Nucleosome Dynamics during Transcription Elongation

(2008) Alastair B. Fleming et al.   MOLECULAR CELL

Distinct Modes of Regulation of the Uch37 Deubiquitinating Enzyme in the Proteasome and in the Ino80 Chromatin-Remodeling Complex

(2008) Tingting Yao et al.   MOLECULAR CELL

Proteasome Regulation of Dynamic Transcription Factor Occupancy on the GnRH-Stimulated Luteinizing Hormone β-Subunit Promoter

(2008) Heidi E. Walsh et al.   MOLECULAR ENDOCRINOLOGY

Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation

(2008) Robert K. McGinty et al.   NATURE

Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation to H3K4 trimethylation

(2008) Adeline Vitaliano-Prunier et al.   NATURE CELL BIOLOGY

Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells

(2008) Neri Minsky et al.   NATURE CELL BIOLOGY

Modulation of RNA polymerase II subunit composition by ubiquitylation

(2008) A. Daulny et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cracking the RNA polymerase II CTD code

(2008) Sylvain Egloff et al.   TRENDS IN GENETICS

Chromatin- and Transcription-Related Factors Repress Transcription from within Coding Regions throughout the Saccharomyces cerevisiae Genome

(2008) Vanessa Cheung et al.   PLOS BIOLOGY