Melatonin and its metabolites vs oxidative stress: From individual actions to collective protection

Diet and supplements in cancer prevention and treatment: Clinical evidences and future perspectives

(2018) Claudio Vernieri et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Computational strategies for predicting free radical scavengers' protection against oxidative stress: Where are we and what might follow?

(2018) Annia Galano et al.   INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY

A new free radical scavenging cascade involving melatonin and three of its metabolites (3OHM, AFMK and AMK)

(2018) Miguel Reina et al.   Computational and Theoretical Chemistry

Oxidative stress and the amyloid beta peptide in Alzheimer’s disease

(2018) C. Cheignon et al.   Redox Biology

Peripheral Oxidative Stress Biomarkers in Mild Cognitive Impairment and Alzheimer's Disease

(2018) Larissa Lobo Torres et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidative Stress in Alzheimer's Disease and Mild Cognitive Impairment with High Sensitivity and Specificity

(2018) Natividad López et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidative Stress and Breast Cancer Risk in Premenopausal Women

(2017) Hazel B. Nichols et al.   EPIDEMIOLOGY

Role of oxidative stress in cardiovascular disease outcomes following exposure to ambient air pollution

(2017) Frank J. Kelly et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genotoxicity of lipid oxidation compounds

(2017) Peter M. Eckl et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress contributes to hepatocyte growth factor-dependent pro-senescence activity of ovarian cancer cells

(2017) Justyna Mikuła-Pietrasik et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pathophysiology of mitochondrial lipid oxidation: Role of 4-hydroxynonenal (4-HNE) and other bioactive lipids in mitochondria

(2017) Mengqing Xiao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds

(2017) Bebiana C. Sousa et al.   FREE RADICAL BIOLOGY AND MEDICINE

In vivo ROS production and use of oxidative stress-derived biomarkers to detect the onset of diseases such as Alzheimer’s disease, Parkinson’s disease, and diabetes

(2017) Aya Umeno et al.   FREE RADICAL RESEARCH

Correlation between Oxidative Stress, Nutrition, and Cancer Initiation

(2017) Subbroto Kumar Saha et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of Melatonin Supplementation on Antioxidant Status and DNA Damage in High Intensity Trained Athletes

(2017) Manuel Ortiz-Franco et al.   INTERNATIONAL JOURNAL OF SPORTS MEDICINE

Copper increases the ability of 6-hydroxydopamine to generate oxidative stress and the ability of ascorbate and glutathione to potentiate this effect: potential implications in Parkinson's disease

(2017) Antón Cruces-Sande et al.   JOURNAL OF NEUROCHEMISTRY

Human transporters, PEPT1/2, facilitate melatonin transportation into mitochondria of cancer cells: An implication of the therapeutic potential

(2017) Xiaokui Huo et al.   JOURNAL OF PINEAL RESEARCH

Melatonin: A pleiotropic molecule that modulates DNA damage response and repair pathways

(2017) Maryam Majidinia et al.   JOURNAL OF PINEAL RESEARCH

Plant mitochondria synthesize melatonin and enhance the tolerance of plants to drought stress

(2017) Lin Wang et al.   JOURNAL OF PINEAL RESEARCH

Melatonin and sirtuins: A “not-so unexpected” relationship

(2017) Juan C. Mayo et al.   JOURNAL OF PINEAL RESEARCH

Taxon- and Site-Specific Melatonin Catabolism

(2017) Rüdiger Hardeland   MOLECULES

Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release

(2017) Yalikun Suofu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer's disease and metabolic syndrome: A link from oxidative stress and inflammation to neurodegeneration

(2017) Eduardo Rojas-Gutierrez et al.   SYNAPSE

Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways

(2017) Zorica Janjetovic et al.   Scientific Reports

Melatonin promotes ATO-induced apoptosis in MCF-7 cells: Proposing novel therapeutic potential for breast cancer

(2016) Elaheh Nooshinfar et al.   BIOMEDICINE & PHARMACOTHERAPY

Oxidative stress markers in type 2 diabetes patients with diabetic nephropathy

(2016) Su-Tze Chou et al.   Clinical and Experimental Nephrology

Sustained release of melatonin: A novel approach in elevating efficacy of tamoxifen in breast cancer treatment

(2016) Mehdi Sabzichi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

The genotoxic effects of anti-cancer drug gossypol on human lymphocytes and its mitigation by melatonin

(2016) Mandava Venkatesh Rao et al.   DRUG AND CHEMICAL TOXICOLOGY

The antioxidative property of melatonin against brain ischemia

(2016) Irene Paterniti et al.   Expert Review of Neurotherapeutics

Cancer metastasis: Mechanisms of inhibition by melatonin

(2016) Shih-Chi Su et al.   JOURNAL OF PINEAL RESEARCH

Apoptosis signaling pathways in osteoarthritis and possible protective role of melatonin

(2016) Azam Hosseinzadeh et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as an antioxidant: under promises but over delivers

(2016) Russel J. Reiter et al.   JOURNAL OF PINEAL RESEARCH

The nuclear melatonin receptor RORαis a novel endogenous defender against myocardial ischemia/reperfusion injury

(2016) Ben He et al.   JOURNAL OF PINEAL RESEARCH

Effects of combination of melatonin and laser irradiation on ovarian cancer cells and endothelial lineage viability

(2016) Maryam Akbarzadeh et al.   LASERS IN MEDICAL SCIENCE

Phenolic Melatonin-Related Compounds: Their Role as Chemical Protectors against Oxidative Stress

(2016) Annia Galano et al.   MOLECULES

Oxidative stress: A major pathogenesis and potential therapeutic target of antioxidative agents in Parkinson’s disease and Alzheimer’s disease

(2016) Tianfang Jiang et al.   PROGRESS IN NEUROBIOLOGY

The key role of the sequential proton loss electron transfer mechanism on the free radical scavenging activity of some melatonin-related compounds

(2016) Ruslán Álvarez-Diduk et al.   THEORETICAL CHEMISTRY ACCOUNTS

The preventative role of exogenous melatonin administration to patients with advanced cancer who are at risk of delirium: study protocol for a randomized controlled trial

(2016) Shirley Harvey Bush et al.   Trials

Food Antioxidants: Chemical Insights at the Molecular Level

(2016) Annia Galano et al.   Annual Review of Food Science and Technology

Effects of melatonin on liver function and lipid peroxidation in a rat model of hepatic ischemia/reperfusion injury

(2016) WEN-SHENG DENG et al.   Experimental and Therapeutic Medicine

Anthranilic acid as a secondary antioxidant: Implications to the inhibition of OH production and the associated oxidative stress

(2016) Misaela Francisco-Marquez et al.   Computational and Theoretical Chemistry

The antioxidative property of melatonin against brain ischemia

(2016) Irene Paterniti et al.   Expert Review of Neurotherapeutics

The Safety of Melatonin in Humans

(2015) Lars Peter Holst Andersen et al.   CLINICAL DRUG INVESTIGATION

Melatonin Leads to Axonal Regeneration, Reduction in Oxidative Stress, and Improved Functional Recovery Following Sciatic Nerve Injury

(2015) Yasemin Kaya et al.   CURRENT NEUROVASCULAR RESEARCH

On the Relationship Between the Light/Dark Cycle, Melatonin and Oxidative Stress

(2015) Ana Colin-Gonzalez et al.   CURRENT PHARMACEUTICAL DESIGN

Melatonin Redox Activity. Its Potential Clinical Applications in Neurodegenerative Disorders

(2015) Elzbieta Miller et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Melatonin ameliorates metabolic risk factors, modulates apoptotic proteins, and protects the rat heart against diabetes-induced apoptosis

(2015) Ali H. Amin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Synergic Effects of Doxorubicin and Melatonin on Apoptosis and Mitochondrial Oxidative Stress in MCF-7 Breast Cancer Cells: Involvement of TRPV1 Channels

(2015) Pınar Aslan Koşar et al.   JOURNAL OF MEMBRANE BIOLOGY

N-Acetylserotonin and 6-Hydroxymelatonin against Oxidative Stress: Implications for the Overall Protection Exerted by Melatonin

(2015) Ruslán Álvarez-Diduk et al.   JOURNAL OF PHYSICAL CHEMISTRY B

HDAC1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways

(2015) Chongxi Fan et al.   JOURNAL OF PINEAL RESEARCH

Melatonin reduces oxidative stress and improves vascular function in pulmonary hypertensive newborn sheep

(2015) Flavio Torres et al.   JOURNAL OF PINEAL RESEARCH

Oxidative stress-induced methemoglobinemia is the silent killer during snakebite: a novel and strategic neutralization by melatonin

(2015) Rachana D. Sharma et al.   JOURNAL OF PINEAL RESEARCH

Melatonin prevents kidney injury in a high salt diet-induced hypertension model by decreasing oxidative stress

(2015) Avshalom Leibowitz et al.   JOURNAL OF PINEAL RESEARCH

Protective effect of melatonin-supported adipose-derived mesenchymal stem cells against small bowel ischemia-reperfusion injury in rat

(2015) Chia-Lo Chang et al.   JOURNAL OF PINEAL RESEARCH

Melatonin attenuates impairments of structural hippocampal neuroplasticity in OXYS rats during active progression of Alzheimer's disease-like pathology

(2015) Natalia A. Stefanova et al.   JOURNAL OF PINEAL RESEARCH

Melatonin uptake through glucose transporters: a new target for melatonin inhibition of cancer

(2015) David Hevia et al.   JOURNAL OF PINEAL RESEARCH

Melatonin decreases muscular oxidative stress and inflammation induced by strenuous exercise and stimulates growth factor synthesis

(2015) Leandro da Silva Borges et al.   JOURNAL OF PINEAL RESEARCH

Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3β pathway in the mouse hippocampus

(2015) Tahir Ali et al.   JOURNAL OF PINEAL RESEARCH

Melatonin: an ancient molecule that makes oxygen metabolically tolerable

(2015) Lucien C. Manchester et al.   JOURNAL OF PINEAL RESEARCH

Melatonin decreases breast cancer metastasis by modulating Rho-associated kinase protein-1 expression

(2015) Thaiz Ferraz Borin et al.   JOURNAL OF PINEAL RESEARCH

Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro

(2015) Tae-Kang Kim et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Phytomelatonin: Assisting Plants to Survive and Thrive

(2015) Russel Reiter et al.   MOLECULES

Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways

(2015) Tatiana V Mishanina et al.   Nature Chemical Biology

The effect of melatonin on spinal cord after ischemia in rats

(2015) S Aydemir et al.   SPINAL CORD

The effect of melatonin on sleep and quality of life in patients with advanced breast cancer

(2015) Pasquale F. Innominato et al.   SUPPORTIVE CARE IN CANCER

Sulfation of 6-hydroxymelatonin, N-acetylserotonin and 4-hydroxyramelteon by the human cytosolic sulfotransferases (SULTs)

(2015) Lijun Luo et al.   XENOBIOTICA

The Effects of Melatonin on Oxidative Stress Parameters and DNA Fragmentation in Testicular Tissue of Rats Exposed to Microwave Radiation

(2015) Dusan Sokolovic et al.   Advances in Clinical and Experimental Medicine

Multiple sclerosis: The role of melatonin and N-acetylserotonin

(2015) George Anderson et al.   Multiple Sclerosis and Related Disorders

Oxidative Stress Markers Correlate with Renal Dysfunction and Thrombocytopenia in Severe Leptospirosis

(2014) Alan M. Araújo et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

A review of melatonin in hepatic ischemia/reperfusion injury and clinical liver disease

(2014) Yue Li et al.   ANNALS OF MEDICINE

The protective effect of melatonin against brain oxidative stress and hyperlocomotion in a rat model of mania induced by ouabain

(2014) Leandro C. Souza et al.   BEHAVIOURAL BRAIN RESEARCH

Hydroxytyrosol ameliorates oxidative stress and mitochondrial dysfunction in doxorubicin-induced cardiotoxicity in rats with breast cancer

(2014) Sergio Granados-Principal et al.   BIOCHEMICAL PHARMACOLOGY

Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow–Robin perivascular spaces

(2014) Russel J. Reiter et al.   Brain Structure & Function

Reactions of Amino Acids, Peptides, and Proteins with Oxidized Metabolites of Tris(p-carboxyltetrathiaaryl)methyl Radical EPR Probes

(2014) Christophe Decroos et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The Role of Melatonin in Multiple Sclerosis, Huntington's Disease and Cerebral Ischemia

(2014) Begona Escribano et al.   CNS & Neurological Disorders-Drug Targets

Cyclic-3-hydroxymelatonin (C3HOM), A Potent Antioxidant, Scavenges Free Radicals and Suppresses Oxidative Reactions

(2014) Dun-Xian Tan et al.   CURRENT MEDICINAL CHEMISTRY

Melatonin in the Biliary Tract and Liver: Health Implications

(2014) Russel Reiter et al.   CURRENT PHARMACEUTICAL DESIGN

The Relationship between Inflammatory and Oxidative Stress Biomarkers, Atherosclerosis and Rheumatic Diseases

(2014) Corina Serban et al.   CURRENT PHARMACEUTICAL DESIGN

Interaction of tryptophan and related compounds with oxygen- and carbon-centered radicals

(2014) R. L. Sverdlov et al.   FREE RADICAL RESEARCH

Oxidative Stress Is Associated With Increased Pulmonary Artery Systolic Pressure in Humans

(2014) Nima Ghasemzadeh et al.   HYPERTENSION

Local Melatoninergic System as the Protector of Skin Integrity

(2014) Andrzej Slominski et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oxidative Stress and Its Significant Roles in Neurodegenerative Diseases and Cancer

(2014) Raynoo Thanan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

N-Acetyl-Serotonin Offers Neuroprotection through Inhibiting Mitochondrial Death Pathways and Autophagic Activation in Experimental Models of Ischemic Injury

(2014) H. Zhou et al.   JOURNAL OF NEUROSCIENCE

Exogenous melatonin supplementation prevents oxidative stress-evoked DNA damage in human spermatozoa

(2014) Ignacio Bejarano et al.   JOURNAL OF PINEAL RESEARCH

Melatonin and its metabolites ameliorate ultraviolet B-induced damage in human epidermal keratinocytes

(2014) Zorica Janjetovic et al.   JOURNAL OF PINEAL RESEARCH

Melatonin reduces cardiac remodeling and improves survival in rats with isoproterenol-induced heart failure

(2014) Fedor Simko et al.   JOURNAL OF PINEAL RESEARCH

Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physicochemical analysis

(2014) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review

(2014) Joaquín J. García et al.   JOURNAL OF PINEAL RESEARCH

Melatonin promotes hepatic differentiation of human dental pulp stem cells: clinical implications for the prevention of liver fibrosis

(2014) Young-Ah Cho et al.   JOURNAL OF PINEAL RESEARCH

A review of metal-catalyzed molecular damage: protection by melatonin

(2014) Alejandro Romero et al.   JOURNAL OF PINEAL RESEARCH

A review of melatonin as a suitable antioxidant against myocardial ischemia-reperfusion injury and clinical heart diseases

(2014) Yang Yang et al.   JOURNAL OF PINEAL RESEARCH

Melatonin: a well-documented antioxidant with conditional pro-oxidant actions

(2014) Hong-Mei Zhang et al.   JOURNAL OF PINEAL RESEARCH

Characterization of a Cross-Linked Protein–Nucleic Acid Substrate Radical in the Reaction Catalyzed by RlmN

(2014) Alexey Silakov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia

(2014) Pallab Bhattacharya et al.   LIFE SCIENCES

Oxidative stress in rheumatoid arthritis patients: relationship to diseases activity

(2014) Mirjana Veselinovic et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Promising Role of Melatonin as Neuroprotectant in Neurodegenerative Pathology

(2014) Neeraj Joshi et al.   MOLECULAR NEUROBIOLOGY

Mechanism of the beneficial effect of melatonin in experimental Parkinson's disease

(2014) Fatos Belgin Yildirim et al.   NEUROCHEMISTRY INTERNATIONAL

Early Onset Alzheimer’s Disease and Oxidative Stress

(2014) Marco Antonio Meraz-Ríos et al.   Oxidative Medicine and Cellular Longevity

N-Acetyl-Serotonin Protects HepG2 Cells from Oxidative Stress Injury Induced by Hydrogen Peroxide

(2014) Jiying Jiang et al.   Oxidative Medicine and Cellular Longevity

Histopathological evaluation of melatonin as a protective agent in heart injury induced by radiation in a rat model

(2014) İclal Gürses et al.   PATHOLOGY RESEARCH AND PRACTICE

Oxidative stress and triglycerides as predictors of subclinical atherosclerosis in prediabetes

(2014) Hayder A. Al-Aubaidy et al.   REDOX REPORT

Essential actions of melatonin in protecting the ovary from oxidative damage

(2014) M.H.C. Cruz et al.   THERIOGENOLOGY

Anticancer effect of salidroside on A549 lung cancer cells through inhibition of oxidative stress and phospho-p38 expression

(2014) JUN WANG et al.   Oncology Letters

Oxidative stress in Alzheimer’s disease

(2014) Zhichun Chen et al.   Neuroscience Bulletin

Melatonin enhances DNA repair capacity possibly by affecting genes involved in DNA damage responsive pathways

(2013) Ran Liu et al.   BMC CELL BIOLOGY

Effects of melatonin on DNA damage induced by cyclophosphamide in rats

(2013) S.G. Ferreira et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Alzheimer´s Disease and Oxidative Stress: A Review

(2013) Miroslav Pohanka   CURRENT MEDICINAL CHEMISTRY

Oxidative stress in carcinogenesis: new synthetic compounds with dual effects upon free radicals and cancer.

(2013) Betul Tekiner-Gulbas et al.   CURRENT MEDICINAL CHEMISTRY

Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells

(2013) Tae-Kang Kim et al.   FASEB JOURNAL

Oxidative stress in atherosclerosis: The role of microRNAs in arterial remodeling

(2013) Anna Zampetaki et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative Stress and DNA Damage in Human Gastric Carcinoma: 8-Oxo-7'8-dihydro-2'-deoxyguanosine (8-oxo-dG) as a Possible Tumor Marker

(2013) Silvia Borrego et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Melatonin in Alzheimer’s Disease

(2013) Li Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oxidative Stress in Alzheimer’s Disease: Are We Connecting the Dots?

(2013) Michela Rosini et al.   JOURNAL OF MEDICINAL CHEMISTRY

Melatonin reduces oxidative stress in the erythrocytes of multiple sclerosis patients with secondary progressive clinical course

(2013) Elżbieta Miller et al.   JOURNAL OF NEUROIMMUNOLOGY

The interaction between oxidative stress and mast cell activation plays a role in acute lung injuries induced by intestinal ischemia–reperfusion

(2013) Weicheng Zhao et al.   JOURNAL OF SURGICAL RESEARCH

Oxidative damage DNA: 8-oxoGua and 8-oxodG as molecular markers of cancer

(2013) Krzysztof Roszkowski et al.   MEDICAL SCIENCE MONITOR

Melatonin ameliorates bisphenol A-induced DNA damage in the germ cells of adult male rats

(2013) Hong-Juan Wu et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Oxidative Stress and Cell Senescence Combine to Cause Maximal Renal Tubular Epithelial Cell Dysfunction and Loss in an in vitro Model of Kidney Disease

(2013) David M. Small et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: A meta-analysis

(2013) M. Schrag et al.   NEUROBIOLOGY OF DISEASE

Effects of memantine and melatonin on signal transduction pathways vascular leakage and brain injury after focal cerebral ischemia in mice

(2013) U. Kilic et al.   NEUROSCIENCE

Oxidative Stress and Nucleic Acid Oxidation in Patients with Chronic Kidney Disease

(2013) Chih-Chien Sung et al.   Oxidative Medicine and Cellular Longevity

Protective Role of Melatonin in Neonatal Diseases

(2013) Eloisa Gitto et al.   Oxidative Medicine and Cellular Longevity

Oxidative Stress and the Pathogenesis of Alzheimer's Disease

(2013) Yan Zhao et al.   Oxidative Medicine and Cellular Longevity

A physicochemical examination of the free radical scavenging activity of Trolox: mechanism, kinetics and influence of the environment

(2013) Marta E. Alberto et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Heart valve disease: The role of calcidiol deficiency, elevated parathyroid hormone levels and oxidative stress in mitral and aortic valve insufficiency

(2013) Esin Eren et al.   REDOX REPORT

Oxidative stress, a common molecular pathway for kidney disease: Role of the redox enzyme p66Shc

(2013) Shi-Kun Yang et al.   RENAL FAILURE

Roles of adiponectin and oxidative stress in obesity-associated metabolic and cardiovascular diseases

(2013) Morihiro Matsuda et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Cyclic 3-hydroxymelatonin, a key metabolite enhancing the peroxyl radical scavenging activity of melatonin

(2013) Annia Galano et al.   RSC Advances

Oxidative Stress Contributes to Lung Injury and Barrier Dysfunction via Microtubule Destabilization

(2012) Eric Kratzer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The antioxidant behaviour of melatonin and structural analogues during lipid peroxidation depends not only on their functional groups but also on the assay system

(2012) Natalia Fagali et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Copper and Oxidative Stress in the Pathogenesis of Alzheimer’s Disease

(2012) Gözde Eskici et al.   BIOCHEMISTRY

Chemistry of phospholipid oxidation

(2012) Ana Reis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Oxidative stress and pulmonary fibrosis

(2012) Paul Cheresh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Chemical Modification of Lysozyme, Glucose 6-Phosphate Dehydrogenase, and Bovine Eye Lens Proteins Induced by Peroxyl Radicals: Role of Oxidizable Amino Acid Residues

(2012) Andrea Arenas et al.   CHEMICAL RESEARCH IN TOXICOLOGY

A New Mouse Model of Dry Eye Disease

(2012) Yuichi Uchino et al.   CORNEA

Melatonin treatment protects liver of Zucker rats after ischemia/reperfusion by diminishing oxidative stress and apoptosis

(2012) Roman Kireev et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Oxidative stress and nitrosative stress are involved in different stages of proteolytic pulmonary emphysema

(2012) Manuella Lanzetti et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease

(2012) Michael H. Yan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress as a potential biomarker for determining disease activity in patients with Rheumatoid Arthritis

(2012) Sunanda Kundu et al.   FREE RADICAL RESEARCH

The role of melatonin treatment in chronic kidney disease

(2012) Marije Russcher   Frontiers in Bioscience-Landmark

Lipid peroxidation biomarkers for evaluating oxidative stress and assessing antioxidant capacity in vivo

(2012) Yasukazu Yoshida et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

In vivo and in vitro evaluation of the use of a newly developed melatonin loaded emulsion combined with UV filters as a protective agent against skin irradiation

(2012) Ana Flo Sierra et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Comparative evaluation of the antioxidant activity of melatonin and related indoles

(2012) M. Isabel Rodriguez-Naranjo et al.   JOURNAL OF FOOD COMPOSITION AND ANALYSIS

Role of oxidative stress in preeclampsia and intrauterine growth restriction

(2012) Ismail Mert et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin

(2012) Tobias W. Fischer et al.   JOURNAL OF PINEAL RESEARCH

A novel enzyme-dependent melatonin metabolite in humans

(2012) Chaoyue Li et al.   JOURNAL OF PINEAL RESEARCH

Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells

(2012) Jingshu Wang et al.   JOURNAL OF PINEAL RESEARCH

Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes

(2012) Dun-Xian Tan et al.   JOURNAL OF PINEAL RESEARCH

On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK

(2012) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Cascade Dissociations of Peptide Cation-Radicals. Part 1. Scope and Effects of Amino Acid Residues in Penta-, Nona-, and Decapeptides

(2012) Thomas W. Chung et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Biomarkers of Oxidative Stress and the Relationship to Cigarette Smoking

(2012) F. J. Lowe et al.   MINI-REVIEWS IN ORGANIC CHEMISTRY

N-Acetylserotonin

(2012) Gianluca Tosini et al.   NEUROSCIENTIST

Oxidative Stress in Alzheimer's and Parkinson's Diseases: Insights from the YeastSaccharomyces cerevisiae

(2012) Catarina Pimentel et al.   Oxidative Medicine and Cellular Longevity

On the evolution of one-electron-oxidized deoxyguanosine in damaged DNA under physiological conditions: a DFT and ONIOM study on proton transfer and equilibrium

(2012) Annia Galano et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Protective effects of melatonin against 12C6+ beam irradiation-induced oxidative stress and DNA injury in the mouse brain

(2011) Z.H. Wu et al.   ADVANCES IN SPACE RESEARCH

Free Radical Lipid Peroxidation: Mechanisms and Analysis

(2011) Huiyong Yin et al.   CHEMICAL REVIEWS

Nutritional Approaches to Modulate Oxidative Stress in Alzheimers Disease

(2011) C. B. Pocernich et al.   Current Alzheimer Research

In Vitroandin VivoAggregation of a Fragment of Huntingtin Protein Directly Causes Free Radical Production

(2011) Sarah Hands et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proton-Coupled Electron Transfer versus Hydrogen Atom Transfer: Generation of Charge-Localized Diabatic States

(2011) Andrew Sirjoosingh et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Is Caffeine a Good Scavenger of Oxygenated Free Radicals?

(2011) Jorge Rafael León-Carmona et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Reaction mechanism of melatonin oxidation by reactive oxygen species in vitro

(2011) Dominique Bonnefont-Rousselot et al.   JOURNAL OF PINEAL RESEARCH

New paradigms in chronic intestinal inflammation and colon cancer: role of melatonin

(2011) Virginia Motilva et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as a natural ally against oxidative stress: a physicochemical examination

(2011) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations

(2011) Carmen Venegas et al.   JOURNAL OF PINEAL RESEARCH

Alzheimer’s disease: pathological mechanisms and the beneficial role of melatonin

(2011) Sergio A. Rosales-Corral et al.   JOURNAL OF PINEAL RESEARCH

Radiation-induced reductive modifications of sulfur-containing amino acids within peptides and proteins

(2011) Chryssostomos Chatgilialoglu et al.   Journal of Proteomics

Oxidative Stress and β-Amyloid Protein in Alzheimer’s Disease

(2011) Zhiyou Cai et al.   NEUROMOLECULAR MEDICINE

Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation

(2011) R Santoro et al.   ONCOGENE

On the direct scavenging activity of melatonin towards hydroxyl and a series of peroxyl radicals

(2011) Annia Galano   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Antioxidant Effects of N-Acetylserotonin

(2010) GREGORY OXENKRUG   Annals of the New York Academy of Sciences

Role of oxidative stress in rheumatoid arthritis: insights from the Nrf2-knockout mice

(2010) C. J. Wruck et al.   ANNALS OF THE RHEUMATIC DISEASES

Exposure of a Monoclonal Antibody, IgG1, to UV-Light Leads to Protein Dithiohemiacetal and Thioether Cross-Links: A Role for Thiyl Radicals?

(2010) Olivier Mozziconacci et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Clinical Uses of Melatonin: Evaluation of Human Trials

(2010) E.J. Sanchez-Barcelo et al.   CURRENT MEDICINAL CHEMISTRY

Clinical Aspects of Melatonin Intervention in Alzheimers Disease Progression

(2010) Daniel P. Cardinali et al.   Current Neuropharmacology

Neurotoxins: Free Radical Mechanisms and Melatonin Protection

(2010) Russel J. Reiter et al.   Current Neuropharmacology

Anti-Amyloidogenic and Anti-Apoptotic Role of Melatonin in Alzheimer Disease

(2010) Hongwen He et al.   Current Neuropharmacology

Respiratory chain cysteine and methionine usage indicate a causal role for thiyl radicals in aging

(2010) Bernd Moosmann   EXPERIMENTAL GERONTOLOGY

The molecular basis of working mechanism of natural polyphenolic antioxidants

(2010) Monica Leopoldini et al.   FOOD CHEMISTRY

Free Radical Scavenging Activity of Ultrashort Single-Walled Carbon Nanotubes with Different Structures through Electron Transfer Reactions

(2010) Ana Martínez et al.   Journal of Physical Chemistry C

The role of melatonin in glaucoma: implications concerning pathophysiological relevance and therapeutic potential

(2010) Agorastos Agorastos et al.   JOURNAL OF PINEAL RESEARCH

Role of melatonin in mucosal gastroprotection against aspirin-induced gastric lesions in humans

(2010) P. C. Konturek et al.   JOURNAL OF PINEAL RESEARCH

Update on the use of melatonin in pediatrics

(2010) Eloisa Gitto et al.   JOURNAL OF PINEAL RESEARCH

Protective effect of melatonin against Opisthorchis viverrini-induced oxidative and nitrosative DNA damage and liver injury in hamsters

(2010) Umawadee Laothong et al.   JOURNAL OF PINEAL RESEARCH

Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease

(2010) Giuseppe Paradies et al.   JOURNAL OF PINEAL RESEARCH

Melatonin treatment normalizes plasma pro-inflammatory cytokines and nitrosative/oxidative stress in patients suffering from Duchenne muscular dystrophy

(2010) Mariam Chahbouni et al.   JOURNAL OF PINEAL RESEARCH

Melatonin ameliorates cerulein-induced pancreatitis by the modulation of nuclear erythroid 2-related factor 2 and nuclear factor-kappaB in rats

(2010) Kyung Hee Jung et al.   JOURNAL OF PINEAL RESEARCH

Oxidative stress in Alzheimer's disease hippocampus: A topographical study

(2010) F.F. Cruz-Sánchez et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Oxidative stress in Alzheimer disease: A possibility for prevention

(2010) David J. Bonda et al.   NEUROPHARMACOLOGY

Theoretical study on the chemical fate of adducts formed through free radical addition reactions to carotenoids

(2010) Ana Martínez et al.   THEORETICAL CHEMISTRY ACCOUNTS

A Reevaluation of the Ambident Reactivity of the Guanine Moiety Towards Hydroxyl Radicals

(2009) Chryssostomos Chatgilialoglu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hypochlorous Acid Reacts with the N-Terminal Methionines of Proteins To Give Dehydromethionine, a Potential Biomarker for Neutrophil-Induced Oxidative Stress

(2009) Jennifer L. Beal et al.   BIOCHEMISTRY

DNA Damage in Human Spermatozoa Is Highly Correlated with the Efficiency of Chromatin Remodeling and the Formation of 8-Hydroxy-2′-Deoxyguanosine, a Marker of Oxidative Stress1

(2009) Geoffry N. De Iuliis et al.   BIOLOGY OF REPRODUCTION

Analysis of 7,8-Dihydro-8-oxo-2′-deoxyguanosine in Cellular DNA during Oxidative Stress

(2009) Dipti Mangal et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The Role of Oxidative Stress and Inflammation in Dry Eye Disease

(2009) Murat Dogru et al.   CORNEA

Status of oxidative stress in rheumatoid arthritis

(2009) Pallinti VASANTHI et al.   International Journal of Rheumatic Diseases

Oxidative stress promotes ocular neovascularization

(2009) Aling Dong et al.   JOURNAL OF CELLULAR PHYSIOLOGY

8-hydroxy-2′ -deoxyguanosine (8-OHdG): A Critical Biomarker of Oxidative Stress and Carcinogenesis

(2009) ATHANASIOS VALAVANIDIS et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

Melatonin and its brain metabolite N1-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice

(2009) Víctor Tapias et al.   JOURNAL OF NEUROSCIENCE RESEARCH

What is Important to Prevent Oxidative Stress? A Theoretical Study on Electron-Transfer Reactions between Carotenoids and Free Radicals

(2009) Ana Martínez et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease

(2009) James M. Olcese et al.   JOURNAL OF PINEAL RESEARCH

Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines

(2009) Rüdiger Hardeland et al.   JOURNAL OF PINEAL RESEARCH

Visualization of melatonin’s multiple mitochondrial levels of protection against mitochondrial Ca2+-mediated permeability transition and beyond in rat brain astrocytes

(2009) Mei-Jie Jou et al.   JOURNAL OF PINEAL RESEARCH

Reactions of the melatonin metaboliteN1-acetyl-5-methoxykynuramine with carbamoyl phosphate and related compounds

(2009) Jana T. Kuesel et al.   JOURNAL OF PINEAL RESEARCH

Differential effects of melatonin on amyloid-β peptide 25-35-induced mitochondrial dysfunction in hippocampal neurons at different stages of culture

(2009) Weiguo Dong et al.   JOURNAL OF PINEAL RESEARCH

Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer

(2009) Brittney Jung-Hynes et al.   JOURNAL OF PINEAL RESEARCH

Guanosine + OH Radical Reaction in Aqueous Solution: A Reinterpretation of the UV−vis Data Based on Thermodynamic and Kinetic Calculations

(2009) Annia Galano et al.   ORGANIC LETTERS

The Role of Oxidative Stress in Chronic Kidney Disease

(2009) Ziad A. Massy et al.   SEMINARS IN DIALYSIS

Endogenous melatonin and oxidatively damaged guanine in DNA

(2009) Zoreh Davanipour et al.   BMC Endocrine Disorders

Oxidatively Generated Damage to the Guanine Moiety of DNA: Mechanistic Aspects and Formation in Cells

(2008) Jean Cadet et al.   ACCOUNTS OF CHEMICAL RESEARCH

Redox-Based Therapeutics for Lung Diseases

(2008) Yuma Hoshino et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidation of myosin by haem proteins generates myosin radicals and protein cross-links

(2008) Marianne N. Lund et al.   BIOCHEMICAL JOURNAL

Amyloid β−Cu2+Complexes in both Monomeric and Fibrillar Forms Do Not Generate H2O2Catalytically but Quench Hydroxyl Radicals†

(2008) Rebecca C. Nadal et al.   BIOCHEMISTRY

Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions

(2008) Angel Catalá   CHEMISTRY AND PHYSICS OF LIPIDS

Melatonin: Quantum-chemical and biochemical investigation of antioxidant activity

(2008) Zhivko A. Velkov et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair

(2008) Tobias W. Fischer et al.   EXPERIMENTAL DERMATOLOGY

Impaired Sulfur-Amino Acid Metabolism and Oxidative Stress in Nonalcoholic Fatty Liver Are Alleviated by Betaine Supplementation in Rats

(2008) Do Y. Kwon et al.   JOURNAL OF NUTRITION

Metabolism of melatonin by cytochrome P450s in rat liver mitochondria and microsomes

(2008) Igor Semak et al.   JOURNAL OF PINEAL RESEARCH

Space radiation-induced inhibition of neurogenesis in the hippocampal dentate gyrus and memory impairment in mice: ameliorative potential of the melatonin metabolite, AFMK

(2008) Kailash Manda et al.   JOURNAL OF PINEAL RESEARCH

The melatonin metaboliteN1-acetyl-5-methoxykynuramine is a potent singlet oxygen scavenger

(2008) Meike Schaefer et al.   JOURNAL OF PINEAL RESEARCH

Oxidative stress of the newborn in the pre- and postnatal period and the clinical utility of melatonin

(2008) Eloisa Gitto et al.   JOURNAL OF PINEAL RESEARCH

A Unified Perspective on the Hydrogen Atom Transfer and Proton-Coupled Electron Transfer Mechanisms in Terms of Topographic Features of the Ground and Excited Potential Energy Surfaces As Exemplified by the Reaction between Phenol and Radicals

(2008) Oksana Tishchenko et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evaluation of oxidative stress markers in neonates with intra-uterine growth retardation

(2008) Zsuzsanna Hracsko et al.   REDOX REPORT

Melatonin in the skin: synthesis, metabolism and functions

(2008) Andrzej Slominski et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Oxidative Stress and Neurotoxicity

(2007) Lawrence M. Sayre et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The Chemical Toxicology of 2-Deoxyribose Oxidation in DNA

(2007) Peter C. Dedon   CHEMICAL RESEARCH IN TOXICOLOGY